Microchemical Journal最新文献

A portable electrolyte concentration and driven microfluidic electrochemical sensing chip for rapid in-situ detection of trace lead ions 一种便携式电解液浓度驱动微流控电化学传感芯片，用于痕量铅离子的快速原位检测

IF 5.2 2区化学

Microchemical Journal Pub Date : 2026-10-16 DOI: 10.1016/j.microc.2026.120021

Qing Zhang, Shangshang Ma, Wei Zhao, Puyu Miao, Ming Yang, Xin Zhuo, Hongwei Shi, Cong Wang, Keying Zhang

{"title":"A portable electrolyte concentration and driven microfluidic electrochemical sensing chip for rapid in-situ detection of trace lead ions","authors":"Qing Zhang, Shangshang Ma, Wei Zhao, Puyu Miao, Ming Yang, Xin Zhuo, Hongwei Shi, Cong Wang, Keying Zhang","doi":"10.1016/j.microc.2026.120021","DOIUrl":"10.1016/j.microc.2026.120021","url":null,"abstract":"<div><div>Heavy metal ions can cause significant damage to food, environment and human health because of their high toxicity, bioaccumulation and non degradability. Therefore, a highly portable microfluidic sensing system was developed for rapid on-site detection of heavy metal ion (Pb<sup>2+</sup> was chosen as a model). Herein, the microfluidic electrochemical sensor utilized the photothermal evaporation effect to accelerate evaporation of water, resulting in formation of concentrated electrolyte solution. Moreover, the photothermal effect can trigger the occurrence of thermocapillary convection, accelerate the capture of Pb<sup>2+</sup> and promote the electrochemical oxidation-reduction process, which can eliminate traditional pre-enrichment process and further improve the electrochemical signals. And the 3D AgNPs-RGO-Ni(OH)<sub>2</sub>@NF with porous and photothermal properties was prepared as a working electrode by one-step hydrothermal method to provide more active sites and electron transfer channels, and coupled with photothermal effect to improve detection performance. The sensor possessed a low detection limit of 0.61 ng/L and a wide detection range (0.001 μg/L–2500 μg/L) for Pb<sup>2+</sup>, and has also achieved excellent test results in actual and spiked samples detection (tap water, fish and human serum). The microfluidic sensor integrated a stable and easy-to-operate photothermal evaporation system into a highly integrated 3D printing device, which was compact, simple and portable, and has broad prospects in the field of heavy metal ions detection.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"231 ","pages":"Article 120021"},"PeriodicalIF":5.2,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D-printed portable dual-mode sensor for sST2 detection in heart failure 用于心衰患者sST2检测的3d打印便携式双模传感器

2区化学

Microchemical Journal Pub Date : 2026-08-29 DOI: 10.1016/j.microc.2026.119558

Xinzhu Huang, Jiaxuan Pu, Yang liu, Yidi Zhang, Guanghua Li, Li Ma

引用次数: 0

Ni-MOF@MIP based fluorescence biomimetic sensor for high selective recognition and sensitive detection of carbendazim in fruit, vegetable, and grain samples 基于Ni-MOF@MIP的荧光仿生传感器，用于水果、蔬菜和谷物样品中多菌灵的高选择性识别和敏感检测

2区化学

Microchemical Journal Pub Date : 2026-08-25 DOI: 10.1016/j.microc.2026.119505

Yueru Ma, Yuqing Yang, Zhiwei Liu, Hongyu Shi, Zixin Jin, Ziwuzhen Wang, Sheng Wei

引用次数: 0

A triblock polyadenine-based dual-signal electrochemical aptasensor for simultaneous detection of zearalenone and ochratoxin A 同时检测玉米赤霉烯酮和赭曲霉毒素A的三阻断块聚腺嘌呤双信号电化学感应传感器

2区化学

Microchemical Journal Pub Date : 2026-08-22 DOI: 10.1016/j.microc.2026.119484

Junjie Huang, Huiqi Yang, Bowen Li, Yihao Li, Yonghong Wang, Ge Ning

引用次数: 0

Smart paper-based chip sensor based on Mn-CeO₂@ persistent-luminescence nanomaterials for tri-modality detection of sarcosine 基于Mn-CeO 2 @持续发光纳米材料的三模态肌氨酸检测智能纸基芯片传感器

2区化学

Microchemical Journal Pub Date : 2026-08-12 DOI: 10.1016/j.microc.2026.119342

Xu-yang Guo, Renagul Abdurahman, Xing-Hong Pan, Rui Zhang, Ling-Hua Zuo, Rui-hong Xu, Tao Li, Xue-Bo Yin, Ming Guan

引用次数: 0

Implantable nanosensor with thin-layer hydrogel antifouling interface for ultrasensitive detection of hydrogen peroxide at the single-cell level 具有薄层水凝胶防污界面的可植入纳米传感器，用于单细胞水平过氧化氢的超灵敏检测

2区化学

Microchemical Journal Pub Date : 2026-07-17 DOI: 10.1016/j.microc.2026.119111

Ziyi Yang, Y W Li, Guanxia Qiu, Qi Xu, Z W Wu, Xi Zhang, S Q Wang, Wei Wen

引用次数: 0

A ratio fluorescence assay for acid phosphatase based on 4-mercaptobenzoic acid templated copper nanoclusters 基于4-巯基苯甲酸模板铜纳米团簇的酸性磷酸酶比例荧光测定

2区化学

Microchemical Journal Pub Date : 2026-07-16 DOI: 10.1016/j.microc.2026.119050

Zhongzhou Si, Haodong Chen, Shakoor Kashif, Ting Li, Fanghui Ma, Minghui Yang

引用次数: 0

Extraction of polysaccharides from Paeoniae Radix Rubra using natural deep eutectic solvents: process optimization, characterization, and neuroprotective effect against MPP+-induced SH-SY5Y cell injury 天然深共熔溶剂提取赤芍多糖：工艺优化、表征及对MPP+诱导的SH-SY5Y细胞损伤的神经保护作用

2区化学

Microchemical Journal Pub Date : 2026-07-14 DOI: 10.1016/j.microc.2026.119070

Fanying Deng, Jinhong Xue, Yu Wang, Yue Sun, Peng Jiang, Yumeng Luo, Zhenqiang Liu, Zhichao Hao, Mengmeng Li, Wei Guan, Qingshan Chen, Lili Zhang, Xiaochi Ma, Haixue Kuang, Yan Liu

引用次数: 0

Direct analysis of illicit drugs in urine by cellulose fiber spray ionization mass spectrometry (CFSI-MS) 纤维素纤维喷雾电离质谱（CFSI-MS）直接分析尿液中违禁药物

IF 5.2 2区化学

Microchemical Journal Pub Date : 2026-07-01 DOI: 10.1016/j.microc.2026.118912

Nathália dos S. Conceição, Bruna C. Pires, Sara Joaquina I. Dionisio, Alan R. Pereira, João Victor M. de Almeida, Sidnei de B.G. Junior, Eclair Venturini Filho, Bruno D. Sabino, Hildegardo S. França, Keyller Bastos Borges, Wanderson Romão, Nayara A. dos Santos

{"title":"Direct analysis of illicit drugs in urine by cellulose fiber spray ionization mass spectrometry (CFSI-MS)","authors":"Nathália dos S. Conceição, Bruna C. Pires, Sara Joaquina I. Dionisio, Alan R. Pereira, João Victor M. de Almeida, Sidnei de B.G. Junior, Eclair Venturini Filho, Bruno D. Sabino, Hildegardo S. França, Keyller Bastos Borges, Wanderson Romão, Nayara A. dos Santos","doi":"10.1016/j.microc.2026.118912","DOIUrl":"10.1016/j.microc.2026.118912","url":null,"abstract":"<div><div>The detection of illicit drugs and their metabolites in human biological samples remains a critical demand in analytical toxicology. The implementation of fast, simple, and selective methods can significantly enhance the efficiency of forensic analyses. In this study, a method was developed for the simultaneous analysis of illicit drugs using an LTQ XL mass spectrometer operated in Selected Ion Monitoring (SIM) and Selected Reaction Monitoring (SRM) modes, coupled with an ambient ionization technique known as Cellulose Fiber Spray Ionization–Mass Spectrometry (CFSI-MS). A fractional factorial design revealed that, in the CFSI(+)LTQ MS mode, voltage and distance were the most influential variables for ionization efficiency. In the CFSI(−)LTQ MS mode, all three tested parameters—substrate mass, voltage, and distance—showed significant effects. Using a central composite design, the optimal experimental conditions were determined: for positively ionizing compounds, the optimal values were 3.367 mm for distance, 5 kV for voltage, and 13.67 mg for substrate mass; for negatively ionizing compounds, the optimal conditions were 6.633 mm, 2 kV, and 13.67 mg, respectively. The findings indicate that the proposed method holds strong potential for the direct and simultaneous analysis of various illicit drugs in biological matrices, with a particular focus on urine.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"228 ","pages":"Article 118912"},"PeriodicalIF":5.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148559257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of an integrated pipeline for characterizing morphological and chemical features of organic crystals in plants 植物有机晶体形态与化学特征综合表征管道的建立

2区化学

Microchemical Journal Pub Date : 2026-06-28 DOI: 10.1016/j.microc.2026.118882

Shipeng Sun, Yue Wang, Weiwei Tang, Ping Li, Bin Li

引用次数: 0