Microchemical Journal最新文献_第2页

High-sensitivity label-free electrochemical genosensors for carbon nanotube plasmon-assisted detection of somatic mutations in nucleic acids from formalin-fixed paraffin-embedded tissues

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-26 DOI: 10.1016/j.microc.2024.112234

V.P. Egorova , H.V. Grushevskaya , N.G. Krylova , E.V. Vaskovtsev , A.S. Babenka , I.V. Anufreyonak , S.Yu. Smirnov , G.G. Krylov

{"title":"High-sensitivity label-free electrochemical genosensors for carbon nanotube plasmon-assisted detection of somatic mutations in nucleic acids from formalin-fixed paraffin-embedded tissues","authors":"V.P. Egorova , H.V. Grushevskaya , N.G. Krylova , E.V. Vaskovtsev , A.S. Babenka , I.V. Anufreyonak , S.Yu. Smirnov , G.G. Krylov","doi":"10.1016/j.microc.2024.112234","DOIUrl":"10.1016/j.microc.2024.112234","url":null,"abstract":"<div><div>Currently, molecular genetic testing of somatic point mutations in the genome of cancer tumors for targeted therapy requires high-performance tools for studies of spatial gene expression and spatial genome profiling in formalin-fixed paraffin-embedded (FFPE) tissue samples. We offer new high-performance label-free electrochemical impedimetric deoxyribonucleic-acid (DNA) nanosensors. The sensors based on a platform of crystalline carbon nanotube plasmonic assemblies are fabricated by the Langmuir–Blodgett deposition technique. The carbon-nanotube assemblies are suspended on nanoporous supports. Incorporation of fast Fourier transforms in the impedance spectroscopy led to the introduction of a new information parameter, the integral value of capacitance changes. The allele-sensitive assay based on plasmon-assisted effects in the assemblies of electrically active conjugates between DNA and few-walled carbon nanotubes has been used for discrimination of allele single-nucleotide polymorphisms (SNPs) of Kirsten Rat Sarcoma viral oncogene homologue (KRAS gene). Using 19- and 20-mer single-stranded (ss) probe oligonucleotides and 35- and 47-mer toehold probes, we explored the probe length and the target location. The genotyping technology allows discrimination of single-nucleotide variations in the target 35-base oligonucleotide at the attomolar concentration level. Human genomic DNAs were isolated from FFPE colorectal cancer tumor tissue samples. The KRAS-gene exon 2, codon 12, c.35G<span><math><mo>></mo></math></span>A mutation has been successfully discriminated in the genomic DNAs with a significance level, P, of 0.001–0.02. The assay has a sensitivity with 0.33-ng/ml limit of detection (LOD) for native genomic DNA.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"208 ","pages":"Article 112234"},"PeriodicalIF":4.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142743793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colorimetric reversibility: Aqueous phase recognition of cyanide using smart phone-based device with real sample analysis

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-26 DOI: 10.1016/j.microc.2024.112259

Jyoti Jangir , Kiran , Anju Ranolia , Priyanka , Sandhya Chahal , Snigdha Singh , Anil Duhan , Rahul Kumar Dhaka , Devender Singh , Parvin Kumar , Jayant Sindhu

{"title":"Colorimetric reversibility: Aqueous phase recognition of cyanide using smart phone-based device with real sample analysis","authors":"Jyoti Jangir , Kiran , Anju Ranolia , Priyanka , Sandhya Chahal , Snigdha Singh , Anil Duhan , Rahul Kumar Dhaka , Devender Singh , Parvin Kumar , Jayant Sindhu","doi":"10.1016/j.microc.2024.112259","DOIUrl":"10.1016/j.microc.2024.112259","url":null,"abstract":"<div><div>A novel colorimetric 2-hydrazinobenzothiazole based probe (<strong>BTHP</strong>) was successfully synthesized and employed as an optical cyanide sensor. The interaction of CN<sup>−</sup> with <strong>BTHP</strong> produced a distinct color variation (dark pink color) with a red shift (96 nm) in its absorption spectra. The probe was selective, sensitive and robust towards cyanide ion sensing even in the presence of other competing ions. It could detect cyanide ion upto 0.77 µM, even lower than the limit recommended by WHO (1.9 µM). The binding stoichiometry for <strong>BTHP-CN<sup>−</sup></strong> complex (1:1) was confirmed <em>via</em> Job’s plot. A binding constant of 3.19*10<sup>2</sup> M<sup>−1</sup> was calculated in the recognition process. The cyanide ion recognition mechanism was confirmed using <sup>1</sup>H NMR titration and DFT calculation. The probe coated filter paper test strips displayed dark pink color upon cyanide exposure. <strong>BTHP</strong> can be used reversibly for the visible detection of cyanide in liquid (real water) as well as solid phase (soil). Further, the practical applications of the developed sensor include smartphone based sensing, logic gate fabrication, molecular keypad lock and write-read-erase-read devices.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"208 ","pages":"Article 112259"},"PeriodicalIF":4.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dispersive solid phase extraction and quadruple isotope dilution–mass spectrometry combination for the accurate and sensitive quantification of capsaicin in pepper, domestic wastewater and human saliva samples by GC–MS system

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-23 DOI: 10.1016/j.microc.2024.112246

Süleyman Bodur , Sezin Erarpat Bodur , Selim Gürsoy , Merve Fırat Ayyıldız , Bedrihan Kartoğlu , Hilal Akbıyık , Ömer Tahir Günkara , Sezgin Bakırdere

{"title":"Dispersive solid phase extraction and quadruple isotope dilution–mass spectrometry combination for the accurate and sensitive quantification of capsaicin in pepper, domestic wastewater and human saliva samples by GC–MS system","authors":"Süleyman Bodur , Sezin Erarpat Bodur , Selim Gürsoy , Merve Fırat Ayyıldız , Bedrihan Kartoğlu , Hilal Akbıyık , Ömer Tahir Günkara , Sezgin Bakırdere","doi":"10.1016/j.microc.2024.112246","DOIUrl":"10.1016/j.microc.2024.112246","url":null,"abstract":"<div><div>In the presented study, reduced graphene oxide/Fe<sub>3</sub>O<sub>4</sub> (rGO/Fe<sub>3</sub>O<sub>4</sub>) nanocomposites based dispersive solid phase extraction (DSPE) – gas chromatography–mass spectrometry (GC–MS) method was developed for the determination of capsaicin in domestic wastewater (DW), pepper (PP) and human saliva (HS) samples. All important parameters of the DSPE method affected the preconcentration factor were carefully optimized to achieve high signal to noise ratio for the analyte. After the optimization studies, the system analytical performance of DSPE-GC–MS system was evaluated using the aqueous standard solution of capsaicin. Limit of detection (LOD), limit of quantitation (LOQ) and dynamic range were figured out to be 0.54 µg/kg, 1.80 µg/kg and 2.66 – 487.35 µg/kg, respectively. Under the optimum experimental conditions, recovery studies were conducted with the spiked DW, PP and HS samples, and percent recovery results were recorded between 52.6 % and 183.6 % via matrix matching calibration strategy. After the implementation of ID<sup>4</sup> strategy, percent recovery results for the spiked DW, PP and HS samples were calculated as 98.2 %–99.3 %, 99.7 %–100.7 % and 99.4 %–99.8 %, respectively. In addition, capsaicin content in Sivri (S)-PP, Kıl (K)-PP and Samandağ (SA)-PP samples were found to be 309.5 ± 11.8 mg/kg, 873.7 ± 26.7 mg/kg and 165.3 ± 5.1 mg/kg via DSPE-GC-ID<sup>4</sup>-MS method, respectively. As a result, the combination of quadruple isotope dilution (ID<sup>4</sup>) strategy and the DSPE-GC–MS method were successfully performed to boost the accuracy and precision of developed DSPE-GC–MS method.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"208 ","pages":"Article 112246"},"PeriodicalIF":4.9,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142743674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances regarding development of effervescence reaction-assisted microextraction techniques for determination of organic pollutants in complex media 开发用于测定复杂介质中有机污染物的逸出反应辅助微萃取技术的最新进展

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-23 DOI: 10.1016/j.microc.2024.112249

Tingting Liu , Mizero Gloria , Xiaofeng Hou , Siyu Shen , Wondimu Andualem Ayele , Hongbing Qin , Qinqin Ma , Hailong Gong , Xuedong Wang

{"title":"Recent advances regarding development of effervescence reaction-assisted microextraction techniques for determination of organic pollutants in complex media","authors":"Tingting Liu , Mizero Gloria , Xiaofeng Hou , Siyu Shen , Wondimu Andualem Ayele , Hongbing Qin , Qinqin Ma , Hailong Gong , Xuedong Wang","doi":"10.1016/j.microc.2024.112249","DOIUrl":"10.1016/j.microc.2024.112249","url":null,"abstract":"<div><div>The effervescence reaction-assisted microextraction (EAM) technology can enhance the efficiency of dispersion technology. The in-situ generation of CO<sub>2</sub> resulting from the reaction between a CO<sub>2</sub> donor and a proton donor forms the basis for the EAM process, effectively dispersing the extractant phase into the sample through the gas produced. After being developed in 2011, EAM technology quickly gained much popularity. Numerous studies have employed it to improve pretreatment procedures. Due to its practical application, low operational cost, reduced solvent usage, excellent extraction efficiency, and environmental friendliness, the EAM technique has garnered significant attention. This article provides a comprehensive overview of the fundamental principles, influencing factors, and methodologies involved in the development of EAM technology in conjunction with large-scale instruments. It specifically focuses on the construction of diverse extractant-based methods for detecting organic pollutants in complex matrices such as environmental samples, food products, and biological specimens. The advantages and disadvantages of these methods are discussed in relation to their practical applications. Furthermore, this review elucidates the effective utilization of this approach for enriching and detecting pollutants within intricate matrices. By conducting a systematic analysis of recent advancements and research cases, this review serves as a valuable reference for advancing environmentally friendly, rapid, and convenient sample pretreatment techniques.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112249"},"PeriodicalIF":4.9,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deciphering versatile electrode materials in the electrochemical progressive processes for flutamide detection: A systematic review 解密氟他胺检测电化学递进过程中的多功能电极材料：系统综述

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-22 DOI: 10.1016/j.microc.2024.112244

Chellapandi Bhuvaneswari , Karuppaiya Palpandi , Boopathi Shagunthala Hariprasad , Chettipalayam Arunasalam Dhayanithi , Natarajan Raman , Periakaruppan Prakash , Sundaram Ganesh Babu

{"title":"Deciphering versatile electrode materials in the electrochemical progressive processes for flutamide detection: A systematic review","authors":"Chellapandi Bhuvaneswari , Karuppaiya Palpandi , Boopathi Shagunthala Hariprasad , Chettipalayam Arunasalam Dhayanithi , Natarajan Raman , Periakaruppan Prakash , Sundaram Ganesh Babu","doi":"10.1016/j.microc.2024.112244","DOIUrl":"10.1016/j.microc.2024.112244","url":null,"abstract":"<div><div>Excess of flutamide causes diseases, therefore excess of anything is undesirable. In order to safeguard human health and the environment, the scientific community battled to monitor hazardous and deadly substances, bacteria, gases, and radiation. So, we focus on the detection of Flutamide (FLT), a non-steroidal anti-androgen drug that is widely used in the treatment of prostatic carcinoma are rapidly attracted interest in the field of medical sciences because it is cherished in monitoring health and environmental conditions and their absurd negative effects when used in excess. This review article focuses on the important advancement in developing mixed and clinical nano samples-based on electrochemical sensors for simultaneous electrochemical sensing of FLT. The fabrication of different electrodes such as Diamond Electrode, Screen Printed Carbon Electrodes (SPCE), Glassy Carbon Electrode (GCE), Gold Electrode (AuE), Carbon Paste Electrode (CPE), and Graphite Pencil Lead Electrode used to detect FLT are highlighted. Furthermore, the challenges of translating different kinds of electrodes with supported nanomaterials-based sensors from the laboratory to the market are considered in future perspectives. This review discusses the selective reports on the different kinds of electrodes to discuss the application of FLT sensors during the period from 2012 to 2024. This review will be a useful tool for researchers, providing new perspectives and ideas for exciting new directions to explore.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112244"},"PeriodicalIF":4.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142720752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of method for SARS-CoV-2 spike protein determination in saliva samples at fg mL−1 levels using electrochemically controlled preconcentration and molecularly imprinted polypyrrole sensor

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-22 DOI: 10.1016/j.microc.2024.112236

Milena do Prado Ferreira , Felipe Augusto Gorla , Mariana Gava Segatelli , Sueli Fumie Yamada Ogatta , Eduardo Costa Figueiredo , César Ricardo Teixeira Tarley

{"title":"Development of method for SARS-CoV-2 spike protein determination in saliva samples at fg mL−1 levels using electrochemically controlled preconcentration and molecularly imprinted polypyrrole sensor","authors":"Milena do Prado Ferreira , Felipe Augusto Gorla , Mariana Gava Segatelli , Sueli Fumie Yamada Ogatta , Eduardo Costa Figueiredo , César Ricardo Teixeira Tarley","doi":"10.1016/j.microc.2024.112236","DOIUrl":"10.1016/j.microc.2024.112236","url":null,"abstract":"<div><div>The present study describes a novel approach for designing a highly sensitive and selective electrochemical sensor for the detection of SARS-CoV-2 in saliva samples by sensing the S-protein, using an electrochemically controlled preconcentration. The sensor is based on electropolymerized molecularly imprinted polypyrrole (PPy) onto a screen-printed carbon electrode (MIP/PPy). The morphology of the MIP/PPy sensor was evaluated by SEM and AFM. The selectivity of the MIP/PPy compared to NIP/PPy was assessed by rebinding S-protein, followed by the monitoring of the redox probe ([Fe(CN)<sub>6</sub>]<sup>3−/4−</sup>). A substantial decrease in the anodic peak current of the redox probe was noticed when using the MIP/PPy. The detectability of the sensor was greatly improved (c.a 1,000,000 fold) by using controlled electrochemical preconcentration of S-protein at +0.6 V for 1.0 min in the rebinding process. Under this condition, a low limit of detection of 6.8fg mL<sup>−1</sup> and an analytical curve in the range of 50.0–125.0 fg mL<sup>−1</sup> (R<sup>2</sup> = 0.996) was obtained. The reproducibility for 10 authentic sensors was highly satisfactory with a relative standard deviation (%,RSD) of 2.8 %. Upon preparation, the sensor can be stored for up to 14 days under refrigeration, with a response efficiency greater than 85 %. The MIP/PPy exhibited high selectivity toward S-protein compared to antitrypsin, human serum albumin (HAS), transferrin, HIgG, and lysozyme. The sensor was applied for detecting SARS-CoV-2 virus through S-protein in infected patients’ saliva samples and validated by RT-PCR. In addition, the satisfactory recovery (91 to 103 %) in S-protein spiked negative samples attested to the free-interference analysis.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"208 ","pages":"Article 112236"},"PeriodicalIF":4.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142743618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nuclear magnetic resonance (NMR) applications in biodiesel characterization and quality – A review 核磁共振 (NMR) 在生物柴油表征和质量中的应用 - 综述

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-19 DOI: 10.1016/j.microc.2024.112226

Alisson Geraldo Alves Ferreira, William Xavier Paula Lima, Rafael Cardoso Rial

{"title":"Nuclear magnetic resonance (NMR) applications in biodiesel characterization and quality – A review","authors":"Alisson Geraldo Alves Ferreira, William Xavier Paula Lima, Rafael Cardoso Rial","doi":"10.1016/j.microc.2024.112226","DOIUrl":"10.1016/j.microc.2024.112226","url":null,"abstract":"<div><div>This manuscript highlights the role of nuclear magnetic resonance (NMR) in assessing the quality and purity of biodiesel. NMR has proven to be an indispensable tool for biodiesel characterization, allowing for precise identification of key physicochemical properties such as methyl ester content, oxidative stability, free fatty acids, and glycerin residues. The ability of 1H NMR to detect impurities, adulterants, and structural changes during production and storage ensures compliance with international standards like ASTM D6751 and EN 14214, which are essential for maintaining biodiesel quality and performance. The study comprehensively compares the application of NMR in analyzing biodiesel from various feedstocks, including vegetable oils, animal fats, and waste oils. NMR’s capacity to discriminate biodiesel sources through specific chemical shifts, such as the methoxy group at 3.6 ppm, and identify contaminants, like water and residual catalysts, highlights its superiority over other analytical techniques like gas chromatography (GC) and Fourier-transform infrared spectroscopy (FTIR). Additionally, the manuscript underscores the importance of NMR in optimizing production processes by evaluating conversion efficiency and identifying by-products. The key contributions of this study lie in its detailed comparison of biodiesel from different feedstocks and its focus on the role of impurities and additives in affecting biodiesel quality. This work confirms NMR’s effectiveness as a reliable, non-destructive tool for ensuring biodiesel purity, making it an essential technique in advancing biodiesel production, improving process efficiency, and promoting the use of sustainable biofuels.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112226"},"PeriodicalIF":4.9,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142706635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanosorbents in solid-phase extraction techniques for bioanalysis: A review 用于生物分析的固相萃取技术中的纳米吸附剂：综述

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-15 DOI: 10.1016/j.microc.2024.112170

Noorfatimah Yahaya , Nur Nadhirah Mohamad Zain , Ahmad Husaini Mohamed , Grasianto , Sazlinda Kamaruzaman , Mazidatulakmam Miskam , Rajeev Jain , Muggundha Raoov , Wan Nazwanie Wan Abdullah

引用次数: 0

Electrochemical methods for the detection of heavy metal ions: From sensors to biosensors 检测重金属离子的电化学方法：从传感器到生物传感器

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-13 DOI: 10.1016/j.microc.2024.112086

Hany Abd El-Raheem , Rabiaa Helim , Rabeay Y.A. Hassan , Ahmed F.A. Youssef , H. Korri-Youssoufi , Charoenkwan Kraiya

{"title":"Electrochemical methods for the detection of heavy metal ions: From sensors to biosensors","authors":"Hany Abd El-Raheem , Rabiaa Helim , Rabeay Y.A. Hassan , Ahmed F.A. Youssef , H. Korri-Youssoufi , Charoenkwan Kraiya","doi":"10.1016/j.microc.2024.112086","DOIUrl":"10.1016/j.microc.2024.112086","url":null,"abstract":"<div><div>Naturally occurring heavy metals (HMs) present a serious risk to human health and the environment because of their toxicity, persistence, and tendency to bioaccumulate. Their presence in air, water, soil, and food can lead to a multitude of adverse effects, from acute poisoning to chronic health problems. The rapid expansion of industrialization and technology has increased HMs contamination from industrial emissions, mining, agriculture, urbanization, and e-waste, posing serious risks to ecosystems and public health. To tackle this increasing challenge, it is essential to develop highly robust, sensitive, and selective electrochemical detection methods for the rapid identification of heavy metal ions (HMIs) contaminants. This review investigates a variety of electrochemical sensors and biosensors utilizing voltammetric techniques for HMIs detection. It covers voltammetric methods such as cyclic voltammetry (CV), square wave voltammetry (SWV), differential-pulse voltammetry (DPV), normal pulse voltammetry (NPV), staircase voltammetry (SV), linear sweep voltammetry (LSV), hydrodynamic voltammetry (HV), anodic stripping voltammetry (ASV), cathodic stripping voltammetry (CSV), and adsorptive stripping voltammetry (AdSV). The review also emphasizes recent advancements in the electrochemical detection of HMIs through various sensor and biosensor platforms, including different nanomaterials and DNA aptamers. These innovations have potential applications in environmental monitoring, food and water safety, industrial waste management, and public health protection, making them vital tools for safeguarding human health and the environment from HMIs contamination.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112086"},"PeriodicalIF":4.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in zearalenone clean-up approaches from polluted food and feed: A mini-review of the State-of-the-art developments 受污染食品和饲料中玉米赤霉烯酮清除方法的最新进展：最新进展小回顾

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-11-13 DOI: 10.1016/j.microc.2024.112182

M.A. Diab , Heba A. El-Sabban , Kwang-Hyun Baek

{"title":"Recent advances in zearalenone clean-up approaches from polluted food and feed: A mini-review of the State-of-the-art developments","authors":"M.A. Diab , Heba A. El-Sabban , Kwang-Hyun Baek","doi":"10.1016/j.microc.2024.112182","DOIUrl":"10.1016/j.microc.2024.112182","url":null,"abstract":"<div><div>Zearalenone (ZEN), a mycotoxin generated by fusarium species, is often found in food and feed and can be extremely harmful to human and animal health. Warranting food safety requires effective extraction of ZEN from contaminated matrices. This mini-review concisely summarizes the most recent ZEN extraction techniques from contaminated food and feed. It highlights firstly various extraction techniques, including liquid–liquid extraction (LLE), solid phase extraction using molecularly imprinted polymers (SPE-MIPs), [Quick, Easy, Cheap, Effective, Rugged, and Safe method (QUEChERS)], green extraction methods such as ultrasound-assisted extraction (UAE), and microwave-assisted extraction (MAE) to improve extraction approaches. Secondly, it discusses recent advanced methods of ZEN detection. This review also discusses the challenges associated with ZEN extraction such as matrix effects, co-contaminants, and the need for standardization method. It emphasizes the importance of continued research to refine existing techniques and develop novel strategies that ensure high efficiency, specificity, and environmental sustainability.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 112182"},"PeriodicalIF":4.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0