Microchemical Journal最新文献

{"title":"Cu2-xSe-based light-controlled LAMP combined Photothermal lateral flow assay for highly sensitive screen of antibiotic resistance gene mecA","authors":"Xin-Lei Hu ,&nbsp;Liu-Feng Yu ,&nbsp;Jie Zhou ,&nbsp;Qing Huang ,&nbsp;Yue Huang ,&nbsp;Yi Zhang ,&nbsp;Li-Xia Yan","doi":"10.1016/j.microc.2026.117324","DOIUrl":"10.1016/j.microc.2026.117324","url":null,"abstract":"<div><div>The detection of antibiotic resistance genes (ARGs) in food is crucial for public health, yet conventional methods like PCR and qPCR are ill-suited for rapid, on-site monitoring due to their complexity and need for specialized equipment. To address this gap, we developed a novel, integrated biosensing platform that combines light-controlled loop-mediated isothermal amplification (LAMP) with a photothermal lateral flow assay (LFA) using dual-functional Cu_2-xSe nanoparticles. This system leverages the high photothermal conversion efficiency of Cu_2-xSe to precisely initiate amplification and generate a quantifiable temperature signal for detection. For the model <em>mecA</em> gene in milk, the method achieved a wide linear range (6.9 to 1.4 × 10⁷ copies μL⁻¹), a low detection limit (1.1 copies μL⁻¹), and satisfactory recoveries within 30 min. This work establishes a strategy that merges photothermal nanomaterial-mediated control with simplified endpoint detection, delivering a sensitive, quantitative, and instrument-minimized solution. It thus represents a significant advance in analytical methodology for point-of-need food safety surveillance.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117324"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous quantification and identification of pesticide and mycotoxin residues via a custom high-resolution tandem mass spectral library and machine learning","authors":"Adeeba Khadim ,&nbsp;Alexey Tarabarov ,&nbsp;Zubia Gulzar ,&nbsp;Sajid Hussain ,&nbsp;Ali Raza ,&nbsp;Syed Ghulam Musharraf ,&nbsp;Chuanguang Qin","doi":"10.1016/j.microc.2026.117296","DOIUrl":"10.1016/j.microc.2026.117296","url":null,"abstract":"<div><div>The persistent accumulation of pesticides and mycotoxins in agricultural products underscores a widespread health issue closely linked to modern diseases. Rapid, multiplexed screening of mycotoxins and pesticides in food is crucial. An open-access HR-MS² library containing 318 pesticides and 58 mycotoxins was developed using QTOF-LC-MS/MS with stepped collision energies (10–60 eV) for [M + H]⁺, [M + Na]⁺, [M + NH₄]⁺, and [M-H]⁻ precursors. Curated spectra and retention-time fingerprints identified 42 pesticides and 6 mycotoxins in food samples. Quantitative analysis revealed concentrations from 0.00125 to 0.0495 mg/kg, with average recoveries of 82% to 118% at 0.01 and 0.1 mg/kg. Differences in contaminant profiles, analyzed using stoichiometric models, uncovered spectral variations among food samples, with some groups showing partial overlap. Four classification models, including random forest (RF), AdaBoost (AB), gradient boosting (GB), and support vector machine (SVM), were applied, and their performance was monitored. A random forest classifier achieved 100% training accuracy and 100% validation accuracy on external data. An open-access HR-MS² library with machine-learning analytics provides scalable, untargeted food-hazard screening for regulators and producers.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117296"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ZIF-derived Cu-Cu3P nanoparticles anchored on N,P co-doped carbon nanocages for efficient detection of hydrazine in food samples","authors":"Ziyu Pu ,&nbsp;Maoyuan Hu ,&nbsp;Jianlong Li ,&nbsp;Qiang Li ,&nbsp;Sheng Li ,&nbsp;Chao Tan ,&nbsp;Xiaoli Xiong","doi":"10.1016/j.microc.2026.117342","DOIUrl":"10.1016/j.microc.2026.117342","url":null,"abstract":"<div><div>The improper use and discharge of hydrazine (HZ) can cause severe environmental pollution and pose threats to human health. Therefore, developing a simple, rapid, sensitive, and low-cost detection method is of great significance for environmental monitoring. In this study, a novel ZIF-derived Cu-Cu₃P nanoparticles anchored on N,P-co-doped hollow carbon nanocages (Cu-Cu₃P/N,P-HCs) was prepared using Zn-ZIF as a self-sacrificial template via a multi-step templating strategy combining template etching and cation exchange methods. The designed catalyst integrates the advantages of the porous and hollow characteristics of metal-organic frameworks (MOFs) derivatives, exhibiting excellent electrocatalytic activity. Using Cu-Cu₃P/N,P-HCs/CP as the working electrode, an efficient and sensitive electrochemical hydrazine sensor was constructed. Experimental results show that the sensor exhibits a wide linear range (5 μM–1 mM and 1 mM–7 mM), with corresponding sensitivities of 5675 μA mM⁻¹ cm⁻² and 2975 μA mM⁻¹ cm⁻², a low detection limit (0.072 μM, S/N = 3) and a fast response (t&lt;3 s). Moreover, the sensor was also successfully applied to the detection of HZ in actual food samples and achieved satisfactory recovery rates. This strategy opens a new avenue for constructing electrochemical sensing electrodes for the detection of food organic pollutants using MOF derivatives.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117342"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-sensitive optical Fiber-based IoT-enabled sensor for HIV detection in smart biomedical monitoring ecosystem","authors":"Md. Anowar Kabir ,&nbsp;Tanusree Saha ,&nbsp;Md. Lutfor Rahaman ,&nbsp;Mst Deloara Khushi ,&nbsp;Md Masud Rana ,&nbsp;Md. Selim Hossain ,&nbsp;Shuvo Sen","doi":"10.1016/j.microc.2026.117318","DOIUrl":"10.1016/j.microc.2026.117318","url":null,"abstract":"<div><div>The Human Immunodeficiency Virus (HIV) is a retroviral pathogen that infects CD₄⁺ T lymphocytes of the human immune system. It leads to immune system suppression. It is also reducing the body's capacity to defend against infections and various diseases. Yet, the existing diagnostic methods of HIV is faced challenges in terms of speed and on-time testing in remote areas. We have designed a Terahertz (THz) based Photonic Crystal Fiber (PCF) sensor with integrating Internet of Things (IoT) for detecting following virus to address this challenge. By analyzing the refractive index changes in infected blood samples, the proposed sensor is detected the virus. It is designed at COMSOL Multiphysics software by following finite element method (FEM) with Maxwell's equations. In the proposed system, the optical output of the PCF sensor is connected to low-power microcontrollers such as the ESP32 or Raspberry Pi Pico W. These microcontrollers convert the sensor signal into digital data and send it to the cloud using IoT technologies like Wi-Fi, MQTT, or LoRaWAN for real-time monitoring. The proposed THz-PCF sensor demonstrates a maximum relative sensitivity (RS) of 96.22% and 96.61% for the x- and y-polarizations, respectively, at the operating frequency of 2.20 THz. Additionally, it achieves low confinement loss (CL) values around 10⁻³ dB/m. Besides, numerical aperture (NA) is bellow than 0.34 operated frequency. The PCF-based IoT integrated biosensor offers a rapid test and non-invasive diagnostic tool. Accurate and efficient detection could significantly advance diagnostic capabilities and therapeutic strategies. The integration of this sensor within an IoT framework enhances its practical utility by enabling remote monitoring and rapid testing. In summary, this innovation opens new avenues in healthcare diagnostics and treatment opportunities.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117318"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146173063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemometric monitoring of critical parameters in rice wine fermentation using near-infrared spectroscopy with ultrasound-assisted S. cerevisiae cultivation","authors":"Jing Hao ,&nbsp;Mengyuan Yang ,&nbsp;Benjamin Kumah Mintah ,&nbsp;Chunhua Dai ,&nbsp;Rong Zhang ,&nbsp;Zhaoli Zhang ,&nbsp;Haile Ma ,&nbsp;Ronghai He","doi":"10.1016/j.microc.2026.117397","DOIUrl":"10.1016/j.microc.2026.117397","url":null,"abstract":"<div><div>This study implemented real-time monitoring of critical process parameters in rice wine fermentation by integrating near-infrared (NIR) spectroscopy with chemometrics. The fermentation process was enhanced through fixed-frequency ultrasound-assisted cultivation of <em>S. cerevisiae</em>, an approach that extends beyond conventional NIR monitoring by incorporating a defined physical pretreatment to actively modify the fermentation system. The conditions for ultrasound-assisted cultivation of <em>S. cerevisiae</em> were logarithmic metaphase, 28 kHz, 20 min and 45 W/L. After screening the feature wavelengths by using the competitive adaptive reweighted sampling (CARS), the <em>Rc</em>, <em>RMSEC</em>, <em>Rp</em> and <em>RMSEP</em> of the correction and prediction models obtained on the basis of the synergy interval partial least square method were as follows: alcohol strength, 0.974, 0.42 and 0.959, 0.51; total sugar content, 0.959, 10.23 and 0.946, 11.55; total acid content, 0.948, 0.25 and 0.939, 0.28; and pH value, 0.960, 0.13 and 0.942, 0.33. The results indicated that the established models are accurate and stable, validating their applicability for real-time bioprocess monitoring in rice wine fermentation with ultrasound-assisted cultivation of <em>S. cerevisiae</em>. These findings highlight the potential of NIR spectroscopy as a rapid, non-destructive tool for optimizing fermentation control in biotechnology applications.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117397"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-enhanced biomechanical analysis of joints during motion and 3D printing of bionic implants","authors":"Sidan Zhang ,&nbsp;Shaojie Shen ,&nbsp;Chen Zhang","doi":"10.1016/j.microc.2026.117112","DOIUrl":"10.1016/j.microc.2026.117112","url":null,"abstract":"<div><div>To address the poor implant integration caused by the mismatch between cross-scale transmission of mechanical signals and inadequate simulation of the cellular microenvironment during joint motion, this paper proposes a gradient multi-material 3D printing method guided by multiscale biomechanical modeling. In the specific implementation, a multiscale finite element model driven by gait data is used to analyze mechanical transmission laws from the tissue to the cellular level during joint movement, and the mechanical window that maintains cellular homeostasis is extracted in reverse by combining atomic force microscopy and molecular pathway analysis. Based on this, a biomimetic design is constructed that couples the elastic modulus index gradient with the distribution of biological factors. Through the fusion process of DLP and inkjet printing, the exposure time and ceramic concentration are controlled to achieve gradient molding of PEGDA/β-TCP composite materials. This paper uses the level set method to optimize the interface topology, generate an interpenetrating network that resists stress concentration, and verify geometric accuracy through confocal imaging, thereby enabling the precise manufacturing of structurally and functionally integrated bionic joint implants. Experiments demonstrate that the proposed method achieves a mean gradient smoothness of at least 4.59 × 10³ μm and a mean stress concentration factor of no more than 1.23 under both loading conditions, effectively mitigating mechanical mismatch at interfaces.</div><div>Furthermore, the proposed method demonstrates the highest compliance matching coverage (average 88.5%–93.7%) across various physiologically relevant interface states, with respect to the accuracy of mechanical parameter reconstruction of the cell microenvironment. The error range is minimal (average range is 3.8 kPa–5.1 kPa), effectively simulating the cellular microenvironment. This work provides a new, programmable, and verifiable path to address the challenge of functional integration between implants and host tissues.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117112"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146147316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isothermal-amplified nucleic acid biosensors for environmental ARG monitoring: principles, platforms, and field readiness","authors":"Qing Lu ,&nbsp;Yu Chang ,&nbsp;Yu Zhou ,&nbsp;Weiying Li","doi":"10.1016/j.microc.2026.117391","DOIUrl":"10.1016/j.microc.2026.117391","url":null,"abstract":"<div><div>As the issue of antibiotic resistance becomes increasingly severe, there is a growing demand for point-of-care testing of resistance genes. Isothermal nucleic acid amplification biosensors, characterized by their efficiency and convenience, have been garnering considerable attention. In this review, we summarize the development of these biosensors over two decades, categorize them into enzyme-assisted and enzyme-free pathways, and systematically analyze their principles, coupling strategies with clustered regularly interspaced short palindromic repeats (CRISPR)/Cas systems, and practical applications in environmental antibiotic resistance gene (ARG) detection. Additionally, we compare the performance, advantages, and disadvantages of different detection systems, such as fluorescence and electrochemical methods, in various application scenarios based on the structural composition of the biosensors. In recent years, the in-depth development of coupling technologies, including CRISPR/Cas systems, DNAzymes, aptamers, has enabled biosensors based on isothermal nucleic acid amplification strategies to achieve detection levels reaching attomolar concentrations. A significant number of studies have demonstrated the feasibility of completing detection processes within minutes, highlighting the potential for real-time or near-real-time testing. However, as an emerging technology, these biosensors face a series of challenges in addressing complex environmental matrices, reducing research and development costs, and enhancing the versatility of devices. Therefore, this review establishes a systematic comparative framework for enzyme-assisted and enzyme-free isothermal amplification strategies, evaluating their performance in environmental ARG detection from the perspectives of sensitivity, inhibitor tolerance, and operational complexity. Meanwhile, it acts as a bridge between technological advances and environmental application demands, focusing on how to address the unique challenges posed by complex environmental matrices and on-site deployability.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117391"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147385965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Matrix-tunable Eu3+/1,10-phenanthroline silica nanomaterials for high-resolution fingerprint development","authors":"Haotian Zhang,&nbsp;Li Liu,&nbsp;Juntong Liu","doi":"10.1016/j.microc.2026.117368","DOIUrl":"10.1016/j.microc.2026.117368","url":null,"abstract":"<div><div>In this study, 1,10-phenanthroline (OP) was employed as an organic sensitizing ligand for Eu³⁺, and three Eu³⁺/OP silica gel fluorescent nanomaterials were prepared via a sol-gel route using tetramethoxysilane (TMOS), tetraethoxysilane (TEOS), and phenyltrimethoxysilane (TMPS) as silica matrices. The enhanced fingerprint developing performance is attributed to combined effects: (1) OP acts as an efficient “antenna” to absorb UV light and transfer energy to Eu³⁺, which allows high-intensity characteristic red emission; (2) Encapsulation in the silica gel forms a microenvironment around the Eu³⁺/OP complexes, which can reduce quenching effects of the surrounding environment; and (3) the surface of the silica gel provides numerous adhesion sites for sebaceous residues, which promotes selective deposition on ridge details and enhances contrast. Using both powder and suspension methods, fingerprints were developed with clear ridge patterns and visible level 2 and level 3 features on various porous/nonporous and smooth/rough substrates. The fingerprints aged (up to 100 days) or soaked in water (up to 50 days) were also successfully developed. These materials show great potential for forensic fingerprint development.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117368"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147385995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of trace amount quercetin with magnetic molecularly imprinted electrochemical sensor sensitized by graphene oxide","authors":"Yanhong Liu ,&nbsp;Xuyang Qin ,&nbsp;Jie Ma ,&nbsp;Qianren Shen ,&nbsp;Qianhuan Wang ,&nbsp;Sixu Chen ,&nbsp;Chunlin Yang ,&nbsp;Wei Li ,&nbsp;Sha Luo ,&nbsp;Chunhui Ma ,&nbsp;Shouxin Liu","doi":"10.1016/j.microc.2026.117332","DOIUrl":"10.1016/j.microc.2026.117332","url":null,"abstract":"<div><div>Molecularly imprinted polymer-based electrochemical sensors (MIP/ECS) have emerged as a promising platform for trace-level pollutant detection, particularly in food safety and environmental monitoring. However, their practical applications are frequently limited by inefficient collection of imprinted materials and sluggish electron-transfer kinetics, which ultimately compromise both selectivity and sensitivity. In this study, we report an innovative MIP/ECS design that integrates Fe₃O₄, graphene oxide (GO), and a molecularly imprinted polymer layer for the ultrasensitive and highly selective detection of quercetin (QR). Systematic investigations demonstrate that the incorporation of Fe₃O₄ enables rapid analyte adsorption under magnetic guidance, while GO significantly enhances electron-transfer efficiency. The polyacrylamide-based imprinted layer provides exceptional recognition specificity toward QR through hydrogen bonding and π–π stacking interactions. As a result, the fabricated sensor exhibits an ultralow LOD of 0.50 nM and a wide dynamic linear range from 0.01 to 1000 μM, comprising two linear regions (0.01–25 μM and 25–1000 μM) with excellent correlation coefficients (R₁² = 0.9973 and R₂² = 0.9997), along with outstanding stability and reliable performance in real-sample analysis. Moreover, the sensor was successfully applied to the determination of QR in <em>Sophora japonica</em> L. buds, onions, and apples, achieving satisfactory recovery values. This work provides a viable and effective strategy for developing high-performance MIP/ECS systems for the precise detection of QR in environmental and food-related samples.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117332"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147386003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanistic insights and environmental validation of a lead dioxide-based sono-electrochemical process for pesticide-contaminated wastewater treatment: Optimization of parameters, kinetic study, and intermediates identification","authors":"Mengxia Wu","doi":"10.1016/j.microc.2026.117330","DOIUrl":"10.1016/j.microc.2026.117330","url":null,"abstract":"<div><div>The persistence of phenylurea herbicides in aquatic systems necessitates innovative treatment strategies that combine efficiency with environmental safety. In this work, a sono–electrochemical approach was developed by coupling low-frequency ultrasound with a PbO₂-coated titanium anode to degrade the model compound Karmex. The electrocatalyst was fabricated and structurally characterized, and its performance was systematically assessed through response surface methodology. The optimized operating conditions (pH 5.7, density 22.35 mA cm⁻², Na₂SO₄ 0.04 mM, 90 min) resulted in nearly complete elimination of the herbicide. Compared with electro-oxidation alone, the hybrid system achieved markedly faster kinetics and higher mineralization efficiency due to the synergistic generation of hydroxyl radicals, supported by electron spin resonance analysis. Degradation intermediates identified by Liquid chromatography–mass spectrometry (LC–MS) pointed to hydroxylation, demethylation, and dehalogenation routes. Trials on agricultural drainage and pesticide-industry effluents confirmed high removal of Karmex (&gt;91%), substantial decreases in chemical oxygen demand (COD) and Biochemical oxygen demand (BOD₅) (&gt;80%), and improved biodegradability without pre-treatment. Acute toxicity assays using <em>Vibrio fischeri</em> demonstrated a significant reduction in ecotoxicity, while the PbO₂ anode exhibited excellent reusability with negligible lead leaching under discharge limits. These findings establish the sono–electrochemical PbO₂ process as a scalable platform for detoxifying pesticide-polluted waters, bridging mechanistic insights with application in sustainable wastewater management.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"223 ","pages":"Article 117330"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}