Microchemical Journal最新文献_第10页

Nanomaterials as signal amplifiers in CRISPR/Cas biosensors: A path toward multiplex point-of-care diagnostics 作为 CRISPR/Cas 生物传感器信号放大器的纳米材料：通向多重护理点诊断的道路

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-10-02 DOI: 10.1016/j.microc.2024.111826

Fareeha Arshad, Bong Jing Yee, Koo Pey Ting, Arifah Arina Syairah Janudin, Muhammad Nadzre Adzremeen bin Amir, Minhaz Uddin Ahmed

{"title":"Nanomaterials as signal amplifiers in CRISPR/Cas biosensors: A path toward multiplex point-of-care diagnostics","authors":"Fareeha Arshad, Bong Jing Yee, Koo Pey Ting, Arifah Arina Syairah Janudin, Muhammad Nadzre Adzremeen bin Amir, Minhaz Uddin Ahmed","doi":"10.1016/j.microc.2024.111826","DOIUrl":"10.1016/j.microc.2024.111826","url":null,"abstract":"<div><div>With the recent shift in perspective in compacting diagnostic laboratories to recreate miniaturised and portable diagnostic tools that can perform rapid, on-site detection, novel nanomaterials have been explored for their application in developing unique point-of-care systems. Upon integration with CRISPR/Cas, it can perform large-scale screening and potentially be applied even under remote conditions, especially in sudden outbreaks and pandemics. Despite the high <em>trans</em>-cleavage activity of the CRISPR/Cas system to give a rapid fluorometric response, their application towards detecting target analytes from complex samples suffers from limited stability and sensitivity. On the contrary, nanomaterials demonstrate robust activity and versatile properties, including rapid optical and electrocatalytic activity, which places them in an ideal position to be applied as signal amplifier systems along with CRISPR/Cas. With the integration of <em>trans</em>-cleavage activity of CRISPR/Cas and nanomaterials, it is possible to develop the next generation of diagnostics that can detect various kinds of biomarkers using different optical and electrochemical transduction methods, which play a crucial role in personalised medicine and precision agriculture. Through this review, we aim to explore the recent advances in the field of CRISPR/Cas – nanomaterial-based biosensors that offer the promising potential to be applied in the highly sensitive and selective detection of multiple target analytes. The potential of applying such biosensors towards developing multiplex biosensors will also be explored, followed by the outlook of this promising diagnostic technology.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111826"},"PeriodicalIF":4.9,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging trends: Smartphone-assisted aptasensors enabling detection of pathogen and chemical contamination 新趋势：能检测病原体和化学污染的智能手机辅助灵敏传感器

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-10-01 DOI: 10.1016/j.microc.2024.111736

Priyanka Garg , Ritika Gupta , Nitesh Priyadarshi , Poonam Sagar , Vishakha Bisht , Naveen K. Navani , Nitin Kumar Singhal

{"title":"Emerging trends: Smartphone-assisted aptasensors enabling detection of pathogen and chemical contamination","authors":"Priyanka Garg , Ritika Gupta , Nitesh Priyadarshi , Poonam Sagar , Vishakha Bisht , Naveen K. Navani , Nitin Kumar Singhal","doi":"10.1016/j.microc.2024.111736","DOIUrl":"10.1016/j.microc.2024.111736","url":null,"abstract":"<div><div>The timely and rapid detection of pathogens and environmental contaminants is critical in safeguarding human health and preventing crises. Pathogens, antibiotic residues, pesticides, and heavy metals pose significant threats to human lives and the economy due to their rapid spread. Developing effective methods for detecting and preventing contaminant spread remains a major challenge. Researchers have been exploring innovative sensing approaches to enable easy, portable, and cost-effective detection using smartphones as versatile sensing tools in recent years. Integrating smartphones with detection assays allows for convenient result acquisition through a simple photograph. Aptamers, with their high affinity and selectivity, have gained substantial interest in biosensing, and they are increasingly employed in the design of novel detection assays based on optical or electrochemical principles. Additionally, smartphone applications can be developed to process images and analyze results based on optical or electrochemical signals, accurately determining pathogen loads. Apart from aptamers, smartphone-based detection platforms also utilize other sensing elements, such as antibodies, carbohydrates, and proteins. Coupling smartphones with detection assays simplifies the detection procedure, making it portable and highly sensitive. This review focuses on the latest technological advancements in smartphone-based devices for biosensing applications, highlighting their potential for rapid pathogen and contaminant detection.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111736"},"PeriodicalIF":4.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive review of state-of-the-art biosensors for detection of allergenic substance lysozyme: A structured recent review and update 用于检测致敏物质溶菌酶的最先进生物传感器综述：近期结构性综述与更新

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-30 DOI: 10.1016/j.microc.2024.111805

Alireza Ebrahimi , Reza Abedi-Firoozjah , Ali Ehsani , Hamed Hamishehkar , Milad Tavassoli

{"title":"A comprehensive review of state-of-the-art biosensors for detection of allergenic substance lysozyme: A structured recent review and update","authors":"Alireza Ebrahimi , Reza Abedi-Firoozjah , Ali Ehsani , Hamed Hamishehkar , Milad Tavassoli","doi":"10.1016/j.microc.2024.111805","DOIUrl":"10.1016/j.microc.2024.111805","url":null,"abstract":"<div><div>Lysozyme (LZM) is a major allergenic protein found in different foods, such as chicken eggs, primarily in the egg white. It can cause adverse reactions in sensitive individuals, leading to symptoms ranging from mild hives to life-threatening anaphylactic shock. Therefore, it’s crucial for those with allergies to avoid any contact with LZM and foods containing it. Reliable analytical methods are essential to ensure consumer safety and improve food production through hazard analysis and good manufacturing practices. The following review article provides an overview of recent progress in biosensors used for the detection of LZM. This article developed a comprehensive review of the main applications of LZM detection, emphasizing the advantages and disadvantages of common analytical techniques such as conventional methods (DNA-based methods and ELISA/Immunochromatography assay/Immunoassay/Mass spectrometry) and modern methods (biosensors such as electrochemical, optical, molecularly imprinted polymers and magnetoelastic sensing). Subsequently, it delves into the developments in biosensors pertaining to the detection mechanisms, including the utilization of nanomaterials as signal probes and carriers for loading signal probes, while also addressing their sensitivity and performance evaluation. Lastly, it discusses the challenges and potential opportunities in the advancement of biosensors for LZM detection.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111805"},"PeriodicalIF":4.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developments and trends in mycotoxin analysis: A review with bibliometric research 霉菌毒素分析的发展与趋势：文献计量学研究综述

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-27 DOI: 10.1016/j.microc.2024.111774

Chuang Wang , Ying Huang , YunYun Wang , Jing Zhang , MengYue Guo , ChangYong Chen , HuiRu Zhang , BinYang Yue , DanDan Kong , JiaoYang Luo , MeiHua Yang

{"title":"Developments and trends in mycotoxin analysis: A review with bibliometric research","authors":"Chuang Wang , Ying Huang , YunYun Wang , Jing Zhang , MengYue Guo , ChangYong Chen , HuiRu Zhang , BinYang Yue , DanDan Kong , JiaoYang Luo , MeiHua Yang","doi":"10.1016/j.microc.2024.111774","DOIUrl":"10.1016/j.microc.2024.111774","url":null,"abstract":"<div><div>Food safety is crucial for human health, and mycotoxins, produced by fungi, can contaminate food, posing a serious health threat. Understanding mycotoxin production, toxicity mechanisms, and accurate detection is essential for food safety. While many studies have explored these aspects, there is still room for improvement in detection methods for mycotoxins. Taking mycotoxins as an entry point, this paper systematically collected and analyzed mycotoxin-related literatures from mainstream databases by combining bibliometric analysis, revealing the development trend and research focuses in this field, confirming mycotoxin detection methods as the core of this review, and further discussing chromatography-based, spectrometry-based, immunoassay-based, biosensor-based, and other. Research advances and limitations of mycotoxin detection methods, such as high sensitivity versus cumbersome processing for chromatography, low cost for spectroscopy, and high specificity for immunoassays, were further discussed. Emerging technologies like immunoassays and biosensors show promise for rapid and portable detection. Challenges in sample preparation and matrix effects are also discussed. Meanwhile, by analyzing the development trend of mycotoxin detection methods, it is predicted that the future research focus will be mainly on the two aspects of highly sensitive and accurate detection and rapid and accurate on-site detection. This review aims to provide insights for the field’s development, predict future trends in mycotoxin analysis, and enhance food safety and public health protection.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111774"},"PeriodicalIF":4.9,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic profiling of plant and other natural products: Platforms, applications and quality evaluation 植物和其他天然产品的代谢分析：平台、应用和质量评估

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-26 DOI: 10.1016/j.microc.2024.111779

Adeyemi O. Adeeyo , Isaac O. Amao , Yvan A.T. Ngandjui , Mercy A. Alabi , Titus A.M. Msagati

引用次数: 0

An advanced early warning technology for coral bleaching crisis based on the electrochemical biosensing of coral-symbiotic zooxanthellae eDNA 基于珊瑚-共生贝藻 eDNA 电化学生物传感的珊瑚白化危机高级预警技术

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-26 DOI: 10.1016/j.microc.2024.111775

Chaoxin Zhang , Hongjie Liu , Shaopeng Wang , Man Zhang , Jiayuan Liang , Hao Fu , Yingmei Wei , Kefu Yu , Liwei Wang

{"title":"An advanced early warning technology for coral bleaching crisis based on the electrochemical biosensing of coral-symbiotic zooxanthellae eDNA","authors":"Chaoxin Zhang , Hongjie Liu , Shaopeng Wang , Man Zhang , Jiayuan Liang , Hao Fu , Yingmei Wei , Kefu Yu , Liwei Wang","doi":"10.1016/j.microc.2024.111775","DOIUrl":"10.1016/j.microc.2024.111775","url":null,"abstract":"<div><div>The symbiotic <em>zooxanthellae</em> in corals are extremely sensitive to the marine environment, and corals bleach rapidly when the symbiotic <em>zooxanthellae</em> are detached from their coral hosts. Currently, ecological monitoring techniques face many problems in coral health assessment, especially coral reef destruction during sampling. In this paper, an electrochemical eDNA biosensor based on ECM/MoS<sub>2</sub> nanocomposites constructed with specific DNA probes was developed to detect the environmental DNA of free <em>zooxanthellae</em> at a low limit of detection (LOD = 0.223 pM) and limit of quantification (LOQ = 0.743 pM) under the experimentally optimized conditions, demonstrating excellent specificity and steadiness. Over and above, the electrochemical response of the biosensor to <em>zooxanthellae</em> DNA was significantly higher than that of other interferent targets, proving its high selectivity. On this basis, the dependability and precision of the biosensor were further verified by comparing the biosensor with ddPCR (<em>P</em> > 0.05, RSD < 5 %). Hence, this electrochemical biosensor can dynamically monitor community changes in <em>zooxanthellae</em> without destroying coral reefs and may serve as a non-invasive method for early warning of coral reef crises. The technique can also be upgraded with portable capabilities in future studies to provide greater convenience in the field analysis of coral bleaching.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111775"},"PeriodicalIF":4.9,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-mode colorimetric–fluorometric immunoassay for foodborne parasitic infection 食源性寄生虫感染的比色-荧光双模式免疫分析法

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-26 DOI: 10.1016/j.microc.2024.111778

Yao Yu , Xiaolei Liu , Ning Xu , Lin Li , Yaming Yang , Mingyuan Liu , Lianjing Zhao , Xue Bai

{"title":"Dual-mode colorimetric–fluorometric immunoassay for foodborne parasitic infection","authors":"Yao Yu , Xiaolei Liu , Ning Xu , Lin Li , Yaming Yang , Mingyuan Liu , Lianjing Zhao , Xue Bai","doi":"10.1016/j.microc.2024.111778","DOIUrl":"10.1016/j.microc.2024.111778","url":null,"abstract":"<div><div>Immunoassays are the primary method used for detection of foodborne parasitic infection. The nanomaterials used in these assays often present challenges such as complex preparation requirements and low stability during long-term storage and transport. Herein, based on cost-effective K<sub>3</sub>[Fe(CN)<sub>6</sub>]-mediated in-situ generated CuFe Prussian blue analogues (CuFe-PBA) and quinoxaline derivatives with high fluorescence, a dual-mode immunoassay was proposed for foodborne parasitic infection. This platform is relied on the restoration of K<sub>3</sub>[Fe(CN)<sub>6</sub>] by ascorbic acid (AA). In addition to this process, K<sub>4</sub>[Fe(CN)<sub>6</sub>]-triggered the generation of CuFe-PBA, and the enhanced fluorogenic reaction of dehydrogenated AA and <em>o</em>-phenylenediamine (OPD) occur sequentially. Without complex probes preparation, the assay enabled the rapid on-site detection of ALP and foodborne parasitic infection through a colorimetric mode accessible via smartphone and offered enhanced sensitivity through a fluorescent mode. The method was used for the detection of ALP, achieving detection limits of 0.38 U/L and 0.03 U/L for colorimetric and fluorescence modes, respectively. Subsequently, the dual-mode immunoassay was applied to <em>Trichinella spiralis</em> infection. The sensitivity and specificity of both the colorimetric and fluorescence modes were 100 % in 950 pig serum samples. This immunosensor provides a universal analysis tool for the accurate, cost-effective and highly sensitive detection of foodborne parasitic infection.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111778"},"PeriodicalIF":4.9,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combination aquaphotomics study and LF-NMR to monitor the drying process of honey pills 结合水生生物组学研究和 LF-NMR 监测蜜丸的干燥过程

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-26 DOI: 10.1016/j.microc.2024.111772

Mengyin Tian , Xiaobo Ma , Lian Li , Aoli Wu , Xue Gao , Zhaoqing Meng , Guiyun Cao , Yi Luo , Lei Nie , Hengchang Zang

{"title":"Combination aquaphotomics study and LF-NMR to monitor the drying process of honey pills","authors":"Mengyin Tian , Xiaobo Ma , Lian Li , Aoli Wu , Xue Gao , Zhaoqing Meng , Guiyun Cao , Yi Luo , Lei Nie , Hengchang Zang","doi":"10.1016/j.microc.2024.111772","DOIUrl":"10.1016/j.microc.2024.111772","url":null,"abstract":"<div><div>As one of the factors affecting the quality of honey pills (HP), there are few researches on its quality control and solutions. But water can directly affect the appearance, stability and potency of the HP. In this study, near-infrared spectroscopy was used to monitor the moisture content of HP with different drying conditions, and multiple linear regression analysis was carried out to establish the moisture content prediction model, and the R<sup>2</sup> of the model prediction is 0.9532. The visualization of HP drying process were carried out by aquaphotomics method characterizes the status of the water molecular network at different drying stages. At the same time, low-field nuclear magnetic resonance (LF-NMR) information was carried out to analyze the water distribution in the drying process, and further verified the water solvent shell action in the water balance process of aquaphotomics analysis. The surface water of the pill disperses to the air, and the internal water diffuses outwards. We adopted the techniques such as rheology to comprehensively characterize the state of HP, and to evaluate the quality of them by using the dissolution test. The quality state of the pills was analyzed by the aquaphotomics analysis of water species. The above research system provided the scientific basis for revealing the drying process of HP from the viewpoint of aquaphotomics, as well as showed potential for expansion and application to other Chinese traditional medicine products.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111772"},"PeriodicalIF":4.9,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

pH sensitive indicator film based intelligent packaging systems of perishables: Developments and challenges of last decade 基于 pH 值敏感指示膜的易腐食品智能包装系统：过去十年的发展与挑战

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-26 DOI: 10.1016/j.microc.2024.111732

Anika Panwar , Satish Kumar , Atul Dhiman , Vikas Kumar , Dharmesh Gupta , Ajay Sharma

{"title":"pH sensitive indicator film based intelligent packaging systems of perishables: Developments and challenges of last decade","authors":"Anika Panwar , Satish Kumar , Atul Dhiman , Vikas Kumar , Dharmesh Gupta , Ajay Sharma","doi":"10.1016/j.microc.2024.111732","DOIUrl":"10.1016/j.microc.2024.111732","url":null,"abstract":"<div><div>Consumers’ demand for novel and non-destructive systems to assess food freshness in real time has led to the development of halochromic or pH-sensitive dyes based freshness indicators (FI) as affordable technique for intelligent monitoring of perishable food. However, the genuine concern regarding the toxicity and deleterious health effect of incorporating conventional synthetic dyes in commercially available halochromic freshness indicators (i.e. fresh tag, checkpoint, and sensorQ) and their sole purpose of monitoring the freshness status of muscle foods (i.e. fish, meat, beef, and shrimp) have led to the revolutionary idea of developing a non-toxic, chemical-free, and sustainable FI based on natural pH-sensitive dyes and polymer matrix. This review delves into significant advances in the chemistry, composition, production, food interaction, stabilization and broad applications of pH-sensitive dyes in the food sector. Unfortunately, the pH-sensitive dyes have reported limited applications in fresh fruit and vegetable industry due to challenges like erratic fluctuations in pH as influenced by factors i.e. high respiration, faster ripening, and environmental changes, inability to distinguish ripening from spoilage, and complex standardization process for specific commodities. These issues merit the demand for further investigations to ensure the utilization of these smart monitoring systems in the modern industry for perishables. The use of FI can potentially play a significant role in reforming food industry, enhance consumer safety, reduce the risk of foodborne illnesses, and aid in the development of a more efficient and sustainable food supply system. Exploration of new natural ingredients and high sensitivity indicators for both animal and plant food products shall drive the innovations in FI for the food industry.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111732"},"PeriodicalIF":4.9,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142418659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorine and boron co doped porous carbon materials as an electrochemical platform in trace-level sodium nitrite sensing 氟和硼共掺杂多孔碳材料作为痕量亚硝酸钠传感的电化学平台

IF 4.9 2区化学

Microchemical Journal Pub Date : 2024-09-25 DOI: 10.1016/j.microc.2024.111769

Nuerbiya Yalikun, Hongzhou gong, Chaofan Liu, Yingshuang Zhang

{"title":"Fluorine and boron co doped porous carbon materials as an electrochemical platform in trace-level sodium nitrite sensing","authors":"Nuerbiya Yalikun, Hongzhou gong, Chaofan Liu, Yingshuang Zhang","doi":"10.1016/j.microc.2024.111769","DOIUrl":"10.1016/j.microc.2024.111769","url":null,"abstract":"<div><div>Sodium nitrite (NaNO<sub>2</sub>) is a common chemical oilfield tracer in the field of reservoir geological analysis. A simple, sensitive, and accurate electrochemical detection method for detection of NaNO<sub>2</sub> has been studied. The electrode carbon porous material was based on coal tar pitch n-pentane insoluble extractants (CTPNI) and doped with the elements of fluorine (F) and boron (B) and labeled as FB-CTPNI-PC and an electrochemical sensor modified with FB-CTPNI-PC material was constructed for rapid detection of NaNO<sub>2</sub>. The characterization results of SEM and TEM indicate that this material has certain number of pore structures, also the BET analysis showed that has main pore size distribution is around the range of 2–20 nm, with abundant mesoporous structure. Moreover, the modified electrode has a good electrocatalytic effect on NaNO<sub>2</sub>. The electrochemical reaction mechanism of NaNO<sub>2</sub> on the surface of the modified electrode was a diffusion-controlled process involving protons. The detection range of NaNO<sub>2</sub> can reach 0.1 mM–9.5 mM. When the S/N is 3, the sensitivity is 219.8592 A·L·cm<sup>2</sup>·mol<sup>−1</sup> and the detection limit (LOD) is 0.011 μM. The constructed electrochemical sensor has been applied to the rapid detection of NaNO<sub>2</sub> in real oilfield water, with recovery rates ranging from 99.7 % to 103.4 %. It is also roughly consistent with the results of ion chromatography (IC) in detecting NaNO<sub>2</sub> in oilfield water, indicating that the sensor has high accuracy. This has provided a new prospect for oil filed tracer and detection technologies.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"207 ","pages":"Article 111769"},"PeriodicalIF":4.9,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0