Materials & Design最新文献_第8页

Al alloying-driven spinodal decomposition enables ultra-strong cast refractory high-entropy alloys 铝合金驱动的spinodal分解使超高强度铸造难熔高熵合金成为可能

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-14 DOI: 10.1016/j.matdes.2025.114736

Yongkang Zhou , Ziyan Zhao , Yuanyuan Wang , Hong Li , Haifeng Zhang , Zhengwang Zhu

{"title":"Al alloying-driven spinodal decomposition enables ultra-strong cast refractory high-entropy alloys","authors":"Yongkang Zhou , Ziyan Zhao , Yuanyuan Wang , Hong Li , Haifeng Zhang , Zhengwang Zhu","doi":"10.1016/j.matdes.2025.114736","DOIUrl":"10.1016/j.matdes.2025.114736","url":null,"abstract":"<div><div>Strengthening in refractory high-entropy alloys (RHEAs) can be achieved through the formation of “compositional heterogeneity” at the atomic scale. Here, we chose Zr<sub>45</sub>Ti<sub>15</sub>Nb<sub>20</sub>Ta<sub>20</sub> alloy with a single-phase body-centered cubic (BCC) structure as a matrix and added a small amount of Al to promote a unique spinodal decomposition. The results show that the introduction of Al-X negative mixing enthalpy induces the RHEAs spinodal decomposition to form a nanocubic structure in the form of a basket-like fabric morphology with a characteristic periodicity of 12 nm. Nanocubic structures consist of (Nb, Ta)-rich cubes and Zr-rich channels as well as generate strong localized strain fields at the interfaces. Spinodal decomposition strengthening enables the as-cast RHEA to achieve a yield strength of 1405 MPa. Periodically distributed nanostructures make dislocations move slowly, causing plugging and cross-slip, facilitating dislocation interactions, multiplication, and accumulation. In summary, the chemical heterostructure produced by spinodal decomposition has been remarkably effective in improving the strength of RHEAs.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114736"},"PeriodicalIF":7.9,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synergistic strength and conductivity enhancement via Induced 〈0 0 1〉-textured ultrafine grains in Al2O3/Cu composites 通过诱导< 0 0 1 >织构的超细晶粒增强Al2O3/Cu复合材料的协同强度和电导率

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-14 DOI: 10.1016/j.matdes.2025.114748

Song Liu , Shaolin Li , Kexing Song , Xiaowen Peng , Xiuhua Guo , Zhenhan Zhou , Shuaibin Li , Fuxiao Chen

{"title":"Synergistic strength and conductivity enhancement via Induced 〈0 0 1〉-textured ultrafine grains in Al2O3/Cu composites","authors":"Song Liu , Shaolin Li , Kexing Song , Xiaowen Peng , Xiuhua Guo , Zhenhan Zhou , Shuaibin Li , Fuxiao Chen","doi":"10.1016/j.matdes.2025.114748","DOIUrl":"10.1016/j.matdes.2025.114748","url":null,"abstract":"<div><div>Overcoming the strength–conductivity trade-off in Al<sub>2</sub>O<sub>3</sub>/Cu composites remains a key challenge. Here, we propose a microstructural design strategy that combines 〈0 0 1〉 texture with elongated ultrafine grains. Room-temperature rotary swaging (RS), assisted by the pinning effect of Al<sub>2</sub>O<sub>3</sub> particles, promotes the selective formation of 〈0 0 1〉-oriented grains through compressive–shear deformation and enhances grain aspect ratios. The resulting structure provides texture-dominated conductive paths while reducing transverse grain boundary density. Consequently, the composite achieves a yield strength of 342 MPa and an electrical conductivity of 95.3 % IACS—representing a 56.8 % strength increase over the Cu matrix without sacrificing conductivity. This work demonstrates a scalable, room-temperature route to high-performance Cu-based composites with an exceptional strength–conductivity balance for advanced electrical applications.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114748"},"PeriodicalIF":7.9,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of dielectric properties, radiation shielding, and electrical resistivity of alkali-activated blast furnace slag and Portland cement binders 碱活化高炉矿渣与硅酸盐水泥粘结剂介电性能、辐射屏蔽性能和电阻率的比较

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-14 DOI: 10.1016/j.matdes.2025.114763

Mehedi Rabbil , Mikko Kokkonen , Elijah Adesanya , Otto Mankinen , Mohammad Bhuyan , Sherif Hegazy , Sami Myllymäki , Juho Yliniemi , Tero Luukkonen

{"title":"Comparison of dielectric properties, radiation shielding, and electrical resistivity of alkali-activated blast furnace slag and Portland cement binders","authors":"Mehedi Rabbil , Mikko Kokkonen , Elijah Adesanya , Otto Mankinen , Mohammad Bhuyan , Sherif Hegazy , Sami Myllymäki , Juho Yliniemi , Tero Luukkonen","doi":"10.1016/j.matdes.2025.114763","DOIUrl":"10.1016/j.matdes.2025.114763","url":null,"abstract":"<div><div>Alkali-activated materials (AAMs) are increasingly explored for sustainable construction, yet their electromagnetic and radiation-related properties remain largely unknown. This study explored the radio wave propagation, gamma-ray shielding efficiency, and electrical resistivity of alkali-activated blast furnace slag (BFS-AAM) compared to hydrated Portland cement (PC). BFS-AAM demonstrated superior relative permittivity (ε<sub>r</sub> ≈ 7.6 at 2.4 GHz) and loss tangent (∼0.33) at lower radio frequencies (0.02–10 GHz), leading to enhanced signal attenuation compared to PC (ε<sub>r</sub> ≈ 5.6, loss tangent ≈ 0.07). BFS-AAM showed similar performance to PC at frequencies between 10–20 GHz, while its characteristics below 10 GHz make it suitable for secure signal environments. In terahertz spectrum (0.2–2 THz), relevant for 6G wireless communication, both materials displayed comparable permittivity (∼5.3 and ∼4.2) and loss tangent (∼0.09 and ∼0.04), indicating compatibility with residential and commercial applications. Simulations at 0.7, 2.4, and 6.0 GHz confirmed higher signal attenuation by BFS-AAM. Additionally, BFS-AAM exhibited higher resistivity (26–110 Ω·m), greater compressive strength (60 MPa), and lower porosity (∼11 %), contributing to its favorable dielectric properties. Although BFS-AAM demonstrated slightly lower gamma-ray shielding efficiency (at 0.661 MeV) than PC, its multifunctional properties position it as promising material for advanced electromagnetic and radiation shielding technologies.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114763"},"PeriodicalIF":7.9,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DNN-based shape optimization of gradient-index phononic crystals with sensitivity analysis for tunable focal position and robust energy harvesting 基于dnn的梯度折射率声子晶体形状优化及其可调焦位和鲁棒能量收集的灵敏度分析

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-14 DOI: 10.1016/j.matdes.2025.114723

Mary Kim , Sangryun Lee

{"title":"DNN-based shape optimization of gradient-index phononic crystals with sensitivity analysis for tunable focal position and robust energy harvesting","authors":"Mary Kim , Sangryun Lee","doi":"10.1016/j.matdes.2025.114723","DOIUrl":"10.1016/j.matdes.2025.114723","url":null,"abstract":"<div><div>Gradient-index (GRIN) phononic crystals (PnCs) enable energy harvesting (EH) by focusing elastic waves into electrical energy. Efficient EH requires maximizing focused wave intensity, typically achieved by tuning the GRIN PnCs unit-cell shape. However, existing designs often exhibit energy concentration near the GRIN lens boundary and incorporate narrow gaps and sharp corners, making them susceptible to manufacturing errors and limiting their practical applicability. Understanding the potential performance changes caused by manufacturing errors is important because geometrical alterations can compromise wave-focusing performance. Therefore, this study aims to optimize the unit-cell shape toward maximum focused intensity at the desired locations for EH devices. To assess manufacturability, the effects of minor geometric variations on the focal position and focused intensity are evaluated via a sensitivity analysis. The optimal shape is derived using a deep neural network (DNN) surrogate model trained to predict focal position and focused intensity. This model accelerates a genetic algorithm (GA) used to perform the optimization. Our optimized designs exhibit 1.5 to 2.0 times higher focused intensity across the target focal positions compared with the conventional design. Thus, these optimal shapes, along with their sensitivity analysis results, provide practical guidelines for defining manufacturing tolerances and achieving consistent, efficient EH performance.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114723"},"PeriodicalIF":7.9,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D-printed barriers with machine learning powered image analysis for enhanced wound healing assays 3d打印屏障与机器学习驱动的图像分析，增强伤口愈合分析

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-14 DOI: 10.1016/j.matdes.2025.114746

Alfredo De Cillis , Valeria Garzarelli , Alessia Foscarini , Giuseppe Gigli , Antonio Turco , Elisabetta Primiceri , Maria Serena Chiriacò , Francesco Ferrara

{"title":"3D-printed barriers with machine learning powered image analysis for enhanced wound healing assays","authors":"Alfredo De Cillis , Valeria Garzarelli , Alessia Foscarini , Giuseppe Gigli , Antonio Turco , Elisabetta Primiceri , Maria Serena Chiriacò , Francesco Ferrara","doi":"10.1016/j.matdes.2025.114746","DOIUrl":"10.1016/j.matdes.2025.114746","url":null,"abstract":"<div><div>Wound healing assay is a standard method enabling investigation of cell proliferation and migration through a cell-free gap in a cell monolayer. Despite very common, it shows several weaknesses: lack of reproducibility and manual and time-based image analysis. Based on novel approach founded on innovative materials and AI-assisted processing of biological images, a promising automated barrier-wound healing assay is realized, achieving consistent results while retaining cells integrity. To increase assay accuracy, biocompatible 3D-printed resin inserts have been developed, facilitating precise control over shape and size of the wound. In parallel, a new image-detection algorithm powered by Deep Learning models was developed to identify cell-free area during the healing process, exceeding limitations of manual analysis. 3D-resin inserts combined with automated image analysis allowed the elimination of subjective errors and provided reproducible quantification of cell-free areas across multiple experiments.</div><div>Moreover, a dataset to train a Convolutional Neural Network for monitor healing over time was developed.</div><div>As proof of concept, this algorithm was tested on a cancer cell line stimulated by TGF-β, a drug stimulating cell migration.</div><div>Innovative design of biocompatible materials combined with Deep Learning for automatically processing high-throughput data enables standardized wound healing assay, increasing efficiency, reliability, and accuracy of results.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114746"},"PeriodicalIF":7.9,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioactive nerve conduit enhance peripheral nerve regeneration through dual functions of ion-regulated dedifferentiation and particle-anchored migration 生物活性神经导管通过离子调节去分化和粒子锚定迁移的双重功能促进周围神经再生

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-14 DOI: 10.1016/j.matdes.2025.114764

Haohui Huang , Shijing Xu , Yulian Yang , Yonghao Qiu , Yujuan Liu , Xiaofeng Chen , Huichang Gao , Fujian Zhao

{"title":"Bioactive nerve conduit enhance peripheral nerve regeneration through dual functions of ion-regulated dedifferentiation and particle-anchored migration","authors":"Haohui Huang , Shijing Xu , Yulian Yang , Yonghao Qiu , Yujuan Liu , Xiaofeng Chen , Huichang Gao , Fujian Zhao","doi":"10.1016/j.matdes.2025.114764","DOIUrl":"10.1016/j.matdes.2025.114764","url":null,"abstract":"<div><div>The regeneration of long-segment peripheral nerve defects remains a critical and challenging clinical problem. The key step in nerve regeneration involves the dedifferentiation of Schwann cells into a repair phenotype, followed by their orderly migration to form Büngner bands that guide axonal elongation. However, due to the lack of bioactive factors for stimulation, the repair of current nerve conduits is generally slow. In this study, we designed a bioactive glass microspheres-embedded nerve conduit. The ions released from these microspheres activate c-Jun to induce Schwann cell dedifferentiation. Meanwhile, the microspheres coated onto the conduit surface provide physical anchoring sites, which accelerate integrin-<em>β</em>1-mediated Schwann cell adhesion and orderly migration to facilitate Büngner bands assembly. This study confirms that dual-function bioactive glass microspheres promote nerve regeneration through ion-regulated dedifferentiation and particle-anchored migration, offering a novel approach for the design of nerve conduits.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114764"},"PeriodicalIF":7.9,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145061508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An ex vivo porcine urethral model for investigating intermittent catheter-associated urethral microtrauma 研究间歇性导尿管相关尿道微创伤的猪离体尿道模型

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-14 DOI: 10.1016/j.matdes.2025.114727

Jane Burns , Robyn N. Irwin , James Quinn , Jessica V. Moore , David Pollard , Ased Ali , James Hands , Colin P. McCoy , Louise Carson , Matthew P. Wylie

{"title":"An ex vivo porcine urethral model for investigating intermittent catheter-associated urethral microtrauma","authors":"Jane Burns , Robyn N. Irwin , James Quinn , Jessica V. Moore , David Pollard , Ased Ali , James Hands , Colin P. McCoy , Louise Carson , Matthew P. Wylie","doi":"10.1016/j.matdes.2025.114727","DOIUrl":"10.1016/j.matdes.2025.114727","url":null,"abstract":"<div><div>Catheter-associated urethral microtrauma is a significant complication of intermittent catheterisation, compromising patient quality of life (QOL) and increasing urinary tract infection risk. Current research is hindered by the lack of robust physiological models to evaluate the mechanical interactions between catheter materials and urethral tissue during intermittent catheterisation. This study introduces the first <em>ex vivo</em> porcine urethral model to investigate tribological performance and material-tissue interactions during intermittent catheter (IC) use, enabling more informed catheter design. We examined four commercial hydrophilic polyvinylpyrrolidone (PVP)-coated ICs and a coating-free integrated amphiphilic surfactant (IAS) IC. ICs were inserted into porcine urethras using a texture analyser, held for two minutes, and withdrawn while measuring force and work done. Post-catheterisation, urethras were examined for microtrauma. Three of four PVP-coated catheters required significantly greater withdrawal force compared to the IAS catheter, correlating with increased urethral transitional membrane damage post-catheterisation. <em>Ex vivo</em> findings suggest that IAS catheters may lower the risk of complications compared with PVP-coated catheters in intermittent catheterisation. This study provides a new platform for comprehensive evaluation of IC-tissue interactions. It underscores the importance of tribological design in medical devices, aiding future innovation in device design and ultimately improve the QOL of patients undergoing intermittent catheterisation.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114727"},"PeriodicalIF":7.9,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anisotropic electrospun poly(ε-caprolactone)/polycarbonate urethane scaffolds with improved fatigue performance for tissue-engineered heart valves 各向异性静电纺丝聚（ε-己内酯）/聚碳酸酯聚氨酯支架在组织工程心脏瓣膜中的抗疲劳性能

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-13 DOI: 10.1016/j.matdes.2025.114762

Zeping Zhang , Rizheng Han , Caihao Huang , Yueen Liu , Guixue Wang , Yun Bai , Rui Yang , Tao Jin , Xing Zhang

{"title":"Anisotropic electrospun poly(ε-caprolactone)/polycarbonate urethane scaffolds with improved fatigue performance for tissue-engineered heart valves","authors":"Zeping Zhang , Rizheng Han , Caihao Huang , Yueen Liu , Guixue Wang , Yun Bai , Rui Yang , Tao Jin , Xing Zhang","doi":"10.1016/j.matdes.2025.114762","DOIUrl":"10.1016/j.matdes.2025.114762","url":null,"abstract":"<div><div>In this study, poly(ε-caprolactone) (PCL) and polycarbonate urethane (PCU) were used to fabricate electrospun scaffolds for tissue-engineered heart valves (TEHVs). The PCL/PCU scaffold containing 25 % PCU (named as 75%PCL-O) with oriented fibers exhibited pronounced anisotropy, with elastic moduli of 53.47 ± 0.93 MPa (X-axis) and 4.19 ± 0.70 MPa (Y-axis), and tensile strength of 14.21 ± 1.16 MPa (X-axis) and 1.59 ± 0.09 MPa (Y-axis), respectively, close to native heart valves. The 75%PCL-O scaffold showed good cell viability and guided cell alignment along the fibers, and no obvious hemolysis or thrombus formation. Hydrodynamic tests showed an effective orifice area (<em>EOA</em>) of 2.42 ± 0.12 cm<sup>2</sup> and a regurgitant fraction (<em>RF</em>) of 5.98 ± 2.31 % for a 25 mm surgical pulmonary valve, meeting the ISO 5840-2 standard. The accelerated fatigue testing demonstrated that the <em>EOA</em> and <em>RF</em> remained stable throughout 50 million cycles. Additionally, finite element analysis (FEA) revealed that mechanical stress concentrated at the free edge for the 75%PCL-O valve leaflet during the opening-closing cycles, correlating well with the observed fiber degradation in these regions during fatigue tests. In summary, the 75%PCL-O scaffold exhibits favorable mechanical performance, good biocompatibility and improved durability, showing great potential for TEHV applications.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114762"},"PeriodicalIF":7.9,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-assembly of bortezomib nanofibers for solid tumor and bone metastasis therapy 硼替佐米纳米纤维自组装用于实体瘤和骨转移治疗

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-13 DOI: 10.1016/j.matdes.2025.114758

Dongjie Fu , Yuerong Wang , Jiaqi Xuan , Dingchang Liu , Jiawei Zhao , Yang Lei , Tianwen Xi , Hui Yang , Leming Sun

{"title":"Self-assembly of bortezomib nanofibers for solid tumor and bone metastasis therapy","authors":"Dongjie Fu , Yuerong Wang , Jiaqi Xuan , Dingchang Liu , Jiawei Zhao , Yang Lei , Tianwen Xi , Hui Yang , Leming Sun","doi":"10.1016/j.matdes.2025.114758","DOIUrl":"10.1016/j.matdes.2025.114758","url":null,"abstract":"<div><div>To overcome challenges including insufficient drug loading capacity, limited targeting accuracy, and the complex preparation of conventional nanomedicine, self-assembled nanomaterials have emerged as a viable solution. To explore the peptide self-assembly theory and overcome limitations, this study used bortezomib (BTZ) as the base material, and a novel peptide self-assembly strategy utilizing Zn(II) coordination was employed to prepare cancer cell-targeting nanofiber drugs (cRGD-BTZNDs). The therapeutic efficacy was evaluated in different types of tumors. The results demonstrated that cRGD-BTZNDs effectively entered cancer cells and exhibited enhanced cytotoxic effects against cancer cells compared to BTZ. Moreover, cRGD-BTZNDs exhibited excellent therapeutic efficacy against solid tumors, significantly inhibiting 4 T1 tumor growth while reducing biological toxicity. Additionally, in the treatment of bone metastases, cRGD-BTZNDs demonstrated excellent therapeutic potency, effectively alleviating bone damage in mice with high biocompatibility. This study not only self-assembled nanomaterials with great potential in cancer therapy, but also affirmed the correctness and universality of the Zn(II) coordination peptide self-assembly theory, providing a theoretical basis for the improvement of peptide-based nanomedicine.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114758"},"PeriodicalIF":7.9,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of γ′ phase on the microstructural evolution and compressive properties of Ni-based single crystal superalloys γ′相对ni基单晶高温合金组织演变及压缩性能的影响

IF 7.9 2区材料科学

Materials & Design Pub Date : 2025-09-13 DOI: 10.1016/j.matdes.2025.114760

Shunyong Zhang , Bin Zhang , Fengpeng Zhao , Jicheng Li , Dong Jia , Xicheng Huang

{"title":"Influence of γ′ phase on the microstructural evolution and compressive properties of Ni-based single crystal superalloys","authors":"Shunyong Zhang , Bin Zhang , Fengpeng Zhao , Jicheng Li , Dong Jia , Xicheng Huang","doi":"10.1016/j.matdes.2025.114760","DOIUrl":"10.1016/j.matdes.2025.114760","url":null,"abstract":"<div><div>To facilitate the evaluation and prediction of hot-end component performance, scanning electron microscopy and quasi-static compression tests were carried out on Ni-based single crystal superalloys, and the influence of γ′ phase on microstructural evolution and compressive properties was systematically investigated. Results show that γ′ phases exhibit spherical, cubic, or lath-like morphologies, and their average size increases from ∼ 180 nm to ∼ 450 nm after thermal exposure; and superalloys with higher volume fraction of γ′ phase gradually precipitate topologically close-packed (TCP) phase. The compressive properties display pronounced anisotropy, governed by both microstructure and loading direction. For superalloys with lower volume fraction of γ′ phase, yield strength decreases from 670 MPa to 505 MPa and ultimate compressive strength from 4690 MPa to 4240 MPa as the γ′ phase coarsens. In contrast, for superalloys with higher volume fraction of γ′ phase, ultimate compressive strength initially decreases and then increases, accompanied by rise in failure strain from 22 % to 46 % after thermal exposure. With increasing loading angle, ultimate compressive strength initially decreases and then rises, whereas yield strength, failure strain and hardening modulus exhibit more complex trends. These variations are closely related to γ′ and TCP phase, and microstructure and loading direction collectively affect mechanical behavior.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"259 ","pages":"Article 114760"},"PeriodicalIF":7.9,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0