Materials & Design最新文献_第8页

Self-locking Fe-based shape memory couplers: Insights into SME and interface contact mechanics 自锁铁基形状记忆耦合器：对SME和界面接触力学的见解

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-16 DOI: 10.1016/j.matdes.2025.114219

Ali Jafarabadi , Maryam Mohri , Elyas Ghafoori , Eleni Chatzi , Christian Leinenbach , Christoph Czaderski

{"title":"Self-locking Fe-based shape memory couplers: Insights into SME and interface contact mechanics","authors":"Ali Jafarabadi , Maryam Mohri , Elyas Ghafoori , Eleni Chatzi , Christian Leinenbach , Christoph Czaderski","doi":"10.1016/j.matdes.2025.114219","DOIUrl":"10.1016/j.matdes.2025.114219","url":null,"abstract":"<div><div>Fe-based Shape memory alloys (Fe-SMAs) have been extensively utilized in a variety of innovative engineering applications. Notably, Fe-based shape memory couplers present an alternative to welded and machined mechanical joints, offering advantages such as self-locking assembly and reduction of stress concentrations. However, further characterization in terms of multiaxial shape memory effect (SME) and, geometrical as well as implementation parameters is crucial for the purpose of reliable strength evaluation. While significant progress has been made toward understanding the uniaxial characteristics of the SME—driven by major developments and widespread use of such materials—the behaviour of Fe-SMAs under complex loading conditions, such as those involving multiaxial phase transformations, remains less well understood. During the pre-straining process of Fe-SMA tubes, non-uniform biaxial stress-state leads to a complex stress-induced martensite formation, posing challenges in the assessment of SME. Nonetheless, it is feasible to interpret the overall SME performance based on the resultant pressure exerted by the Fe-SMA tube on a substance, thereby limiting its free recovery. This study explores the impact of heat-treatment, pre-straining level, activation temperature and wall-thickness on interface contact pressure, providing insights into the gripping capacity in Fe-SMA tubes, which is crucial for evaluating the strength of shape memory joints. Via coupling of analytical models with results extracted from an experimental campaign, the resultant pressure at the interface throughout the course of activation is quantified, aiding to assess the SME performance. The obtained results highlight the complex interaction between post-processing and structural parameters, shedding light on the design and implementation of Fe-SMA coupling components with enhanced SME performance.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"256 ","pages":"Article 114219"},"PeriodicalIF":7.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144291662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conditional generative AI for high-fidelity synthesis of hydrating cementitious microstructures 高保真水化胶凝微观结构合成的条件生成人工智能

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-16 DOI: 10.1016/j.matdes.2025.114251

Minfei Liang , Kun Feng , Jinbao Xie , Yuyang Wei , Sonia Contera , Erik Schlangen , Branko Šavija

{"title":"Conditional generative AI for high-fidelity synthesis of hydrating cementitious microstructures","authors":"Minfei Liang , Kun Feng , Jinbao Xie , Yuyang Wei , Sonia Contera , Erik Schlangen , Branko Šavija","doi":"10.1016/j.matdes.2025.114251","DOIUrl":"10.1016/j.matdes.2025.114251","url":null,"abstract":"<div><div>Portland cement paste has a highly heterogenous evolving microstructure that complicates the development of stronger and greener cementitious materials. Microstructure is the fundamental input of multiscale studies on material behaviors. Herein, we propose a conditional generative AI framework for synthesizing high-fidelity 3D microstructures of hydrating cement paste (1–28 days) with varying water-to-cement ratios and Blaine fineness values. A latent diffusion transformer, operating within a compact two-stage latent space derived via a vector quantized variational autoencoder, efficiently captures and reproduces experimentally measured microstructural patterns. Statistical analyses confirm strong consistency in grey value distributions, micromechanical properties, hydration phase evolution, and particle size distributions, with only minor boundary-related discrepancies. Validation using a pretrained classifier further corroborates the fidelity of generated microstructures. This approach provides a robust tool for realistic cement paste microstructure generation, supporting multiscale modeling and advancing the design of sustainable cementitious materials.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"256 ","pages":"Article 114251"},"PeriodicalIF":7.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristic analysis of innermost layer of ITZ of cement paste based on modelling the spatial distribution of calcium hydroxide 基于氢氧化钙空间分布模型的水泥浆体ITZ最内层特性分析

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-16 DOI: 10.1016/j.matdes.2025.114249

Yuting Chu , Qijun Yu , Yang Yu , Peng Gao , Binggen Zhan

引用次数: 0

PLLA/PEO blend as self-curing material for a biodegradable Eustachian tube stent PLLA/PEO共混自固化材料用于可生物降解耳咽管支架

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-16 DOI: 10.1016/j.matdes.2025.114255

Stefan Oschatz , Selina Schultz , Nicklas Fiedler , Jana Markhoff , Michael Teske , Daniela Koper , Volkmar Senz , Christoph Brandt-Wunderlich , Klaus-Peter Schmitz , Niels Grabow , Kerstin Lebahn

{"title":"PLLA/PEO blend as self-curing material for a biodegradable Eustachian tube stent","authors":"Stefan Oschatz , Selina Schultz , Nicklas Fiedler , Jana Markhoff , Michael Teske , Daniela Koper , Volkmar Senz , Christoph Brandt-Wunderlich , Klaus-Peter Schmitz , Niels Grabow , Kerstin Lebahn","doi":"10.1016/j.matdes.2025.114255","DOIUrl":"10.1016/j.matdes.2025.114255","url":null,"abstract":"<div><div>Within this work, blending of high molecular weight (HMW) PLLA with HMW polyethylene oxide (PEO) as self-curing biodegradable stent material for potential treatment of Eustachian tube dysfunction (ETD) is reported. Blending with PEO significantly enhances the material’s mechanical properties, enabling the stent to conform to the non-circular, tapered cross-sectional shape of the Eustachian tube (ET). Elution of PEO leads to self-curing of the stent, enabling long-term support of the ET. The PLLA/PEO stents were able to withstand radial deformation of up to 33 % and up to 12 %. Radial strength of the stent prototypes (90/10: 203 ± 37 kPa and 80/20: 232 ± 52 kPa) was slightly lower compared to the benchmarked commercial Absorb, Elixir and RevaMedical stents (250/218/318 kPa), but exceeded the values of the former two after 7 d post-curing <em>in vitro</em> (90/10: 301 ± 59 kPa and 80/20: 324 ± 12 kPa). Radial stiffness (90/10: 7.63 ± 2.74 kPa and 80/20: 9.15 ± 3.03 kPa) was also comparable (Absorb/Elixir/RevaMedical stents: 6.08/5.31/6.99), but increased to 15.07 ± 2.57 kPa (90/10) and 15.89 ± 1.53 kPa (80/20) after PEO elution over 7d <em>in vitro</em>, substantially increasing scaffolding properties.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"256 ","pages":"Article 114255"},"PeriodicalIF":7.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrospun piezoresistive pressure sensor integrated into a soft ball for portable, battery-free monitoring of hand grip strength 电纺丝压阻式压力传感器集成在一个软球中，用于便携式，无电池监测手的握力

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-16 DOI: 10.1016/j.matdes.2025.114257

Abdulkadir Sanli

引用次数: 0

Injectable hyaluronic acid hydrogel for corneal neovascularization management by inhibiting oxidative stress, inflammation and neovascularization 注射透明质酸水凝胶通过抑制氧化应激，炎症和新生血管管理角膜

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-15 DOI: 10.1016/j.matdes.2025.114248

Yingying Wei , Jiahao Xu , Xu Yang , Qing Wang , Linyu Long , Daihua Fu , Fanjun Zhang , Shibo Tang , Yunbing Wang

{"title":"Injectable hyaluronic acid hydrogel for corneal neovascularization management by inhibiting oxidative stress, inflammation and neovascularization","authors":"Yingying Wei , Jiahao Xu , Xu Yang , Qing Wang , Linyu Long , Daihua Fu , Fanjun Zhang , Shibo Tang , Yunbing Wang","doi":"10.1016/j.matdes.2025.114248","DOIUrl":"10.1016/j.matdes.2025.114248","url":null,"abstract":"<div><div>Corneal neovascularization (CNV) represents a significant global contributor to vision impairment and blindness. Nonetheless, existing therapeutic modalities, including surgical interventions and pharmacological treatments, face challenges related to limited efficacy and potential adverse effects. In this study, we developed a hydrogel formulation for the targeted delivery of the anti-angiogenic peptide KV11 leveraging multiple physicochemical interactions among adipic dihydrazide-modified hyaluronic acid (AHA), protocatechuic aldehyde (PA), and MnO<sub>2</sub>. The incorporation of PA and MnO<sub>2</sub> conferred antioxidant properties to the hydrogel, enabling it to effectively scavenge DPPH free radicals and hydroxyl radicals. Therefore, the hydrogel demonstrated notable antioxidant and anti-apoptotic effects in human corneal epithelial cells (HCECs) and effectively inhibited M1 macrophage polarization <em>in vitro</em>. Additionally, the hydrogel formulation was capable of suppressing the migration and proliferation of endothelial cells. Treatment with the KV11-loaded hydrogel significantly ameliorated pathological corneal injury in a rat model of alkali burn-induced CNV. Furthermore, the hydrogel material demonstrated safety and non-toxicity to the ocular surface. This study designed a multifunctional HA hydrogel formulation by integrating materials with antioxidant properties, specifically PA and MnO<sub>2</sub>, along with KV11, effectively addressing the complex challenges posed by oxidative stress, acute inflammatory responses, and neovascularization, providing a promising strategy for the treatment of CNV.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"256 ","pages":"Article 114248"},"PeriodicalIF":7.6,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatiotemporal Regulation of Ferrocene-Based MOFs: Harnessing Photothermal “Local Storm” and “Systemic Immune Cruise 二茂铁mof的时空调控：利用光热“局部风暴”和“系统免疫巡航”

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-15 DOI: 10.1016/j.matdes.2025.114246

Bing Gao , Lili Tu , Fulin Liu , Jianping Li , Jing Fu

{"title":"Spatiotemporal Regulation of Ferrocene-Based MOFs: Harnessing Photothermal “Local Storm” and “Systemic Immune Cruise","authors":"Bing Gao , Lili Tu , Fulin Liu , Jianping Li , Jing Fu","doi":"10.1016/j.matdes.2025.114246","DOIUrl":"10.1016/j.matdes.2025.114246","url":null,"abstract":"<div><div>Ovarian cancer ranks among the most prevalent gynecologic malignancies, characterized by a high incidence and poor prognosis. However, the efficacy of conventional chemotherapy is often compromised by systemic toxicity and insufficient immune activation. To address these challenges, a zirconium-ferrocenyl metal–organic framework modified with the immune adjuvant glucan (Zr-Fc-MOF@Glu) was rationally designed to enable spatiotemporally controlled photothermal immunotherapy. Upon near-infrared (NIR) irradiation, Zr-Fc-MOF@Glu generates a localized photothermal effect, inducing tumor cell apoptosis and triggering an inflammatory “storm” within the tumor microenvironment. Concurrently, the glucan component acts as an immunomodulator, amplifying immune activation and initiating a robust systemic immune response, thereby enabling a “systemic immune cruise.” Both in vitro and in vivo evaluations demonstrated that this approach effectively inhibited tumor growth, enhanced immune responses, and minimized adverse effects. By integrating photothermal-induced local inflammatory activation with systemic immune mobilization, this strategy presents a promising avenue for precise and efficacious ovarian cancer therapy.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"256 ","pages":"Article 114246"},"PeriodicalIF":7.6,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144322450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formation and deformation mechanisms of gradient structures: The role of strain hardening 梯度结构的形成和变形机制：应变硬化的作用

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-15 DOI: 10.1016/j.matdes.2025.114245

Taifeng Cao , Zhouzhu Mao , Shiyu Du , Xiaofeng Qin , Aiguo Pi , Tuanwei Zhang , Zhihua Wang

{"title":"Formation and deformation mechanisms of gradient structures: The role of strain hardening","authors":"Taifeng Cao , Zhouzhu Mao , Shiyu Du , Xiaofeng Qin , Aiguo Pi , Tuanwei Zhang , Zhihua Wang","doi":"10.1016/j.matdes.2025.114245","DOIUrl":"10.1016/j.matdes.2025.114245","url":null,"abstract":"<div><div>Gradient structures (GS) have emerged as a focal point due to their capability to overcome the performance limitations of homogeneous materials. In this study, GS was prepared using the cyclic torsion method for low-carbon (LC) and twinning-induced plasticity (TP) steel, aiming to investigate the effect of strain hardening ability on the formation and deformation mechanisms of GS. The TP-GS steels exhibit a significant gradient distribution of hardness, dislocation cells (DCs), subgrains, stacking faults (SFs), and deformation twins (DTs). In contrast, LC-GS steels display only a dislocation density gradient. Finite element modelling (FEM) revealed the difference in stress gradient between two steels. After tensile deformation, denser, finer, and multi-level DTs are observed at the edge region of TP-GS steels, whereas the DCs in the center region evolve into dense SFs and DTs, preserving the significant gradient microstructure. Hardness and microstructure distributions reveal a “dynamic-enhanced gradient effect” at both the edge and center regions of TP-GS steels, leading to an excellent synergy of strength, plasticity, and work hardening ability. In contrast, LC-GS steels rely solely on the deformation potential of the center region, resulting in a “dynamic-weakened gradient effect”. This finding offers valuable insights for the design and preparation of GS.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"256 ","pages":"Article 114245"},"PeriodicalIF":7.6,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144291664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Piezoelectric copper-doped bioactive glass composite dressing for antibacterial-immune synergistic regulation and wound healing 压电铜掺杂生物活性玻璃复合敷料抗菌免疫协同调节及伤口愈合

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-15 DOI: 10.1016/j.matdes.2025.114247

Jungang Luo , Difeng Zheng , Biao Lu , Xianqiang Ding , Miaofeng Wang , Bin Fang , Sunyang Fang , Haijiang Qiu

{"title":"Piezoelectric copper-doped bioactive glass composite dressing for antibacterial-immune synergistic regulation and wound healing","authors":"Jungang Luo , Difeng Zheng , Biao Lu , Xianqiang Ding , Miaofeng Wang , Bin Fang , Sunyang Fang , Haijiang Qiu","doi":"10.1016/j.matdes.2025.114247","DOIUrl":"10.1016/j.matdes.2025.114247","url":null,"abstract":"<div><div>The core mechanism underlying infection-related wound healing difficulties is closely linked to the disruption of the local immune microenvironment. Macrophages, as central cells in immune regulation, play a pivotal role, and their functional imbalance is a critical factor contributing to healing impairment. Hence, we designed and fabricated a multifunctional electrospun dressing—PLLA@Cu—by incorporating copper-doped bioactive glass (Cu-MBG) nanoparticles into polarized PLLA fibers, resulting in a composite material with piezoelectric properties. Under the synergistic effect of ultrasound (US) and copper ions (Cu<sup>2+</sup>), PLLA@Cu exhibited remarkable antibacterial activity. Additionally, it effectively promoted M1 macrophage polarization, significantly enhancing their phagocytic and bactericidal capabilities. In vivo experiments demonstrated that PLLA@Cu could rapidly eliminate infecting bacteria, while modulating macrophage polarization to improve the immune microenvironment of the wound. This resulted in increased collagen deposition and enhanced angiogenesis, significantly accelerating wound healing. Furthermore, the material promoted cell adhesion and accelerated re-epithelialization by increasing surface energy and roughness. Therefore, the multifunctional electrospun dressing developed in this study holds great potential for treating infected wounds and shows promise as a novel candidate material for wound healing applications.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"256 ","pages":"Article 114247"},"PeriodicalIF":7.6,"publicationDate":"2025-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144331436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multimodal analysis of aluminum-steel dissimilar joint interface: Strength improvement mechanism through Ni addition 铝-钢异种接头界面的多模态分析：添加Ni提高强度的机理

IF 7.6 2区材料科学

Materials & Design Pub Date : 2025-06-14 DOI: 10.1016/j.matdes.2025.114236

Kiyoaki T. Suzuki , Shun Tokita , Sylvain Dancette , Yutaka S. Sato

{"title":"Multimodal analysis of aluminum-steel dissimilar joint interface: Strength improvement mechanism through Ni addition","authors":"Kiyoaki T. Suzuki , Shun Tokita , Sylvain Dancette , Yutaka S. Sato","doi":"10.1016/j.matdes.2025.114236","DOIUrl":"10.1016/j.matdes.2025.114236","url":null,"abstract":"<div><div>To reduce vehicle weight and CO<sub>2</sub> emissions, multi-material automotive structures combining Al alloys with steel are in high demand. However, dissimilar joining of Al alloys to steel is still challenging due to the formation of a brittle intermetallic layer (IML) at the joint interface, which deteriorates joint strength. In this study, the effect of Ni on the joint strength, microstructure, and local mechanical properties of the IML of Al/steel joints was examined. Although the Ni increased the IML thickness, it significantly increased the joint strength by 138%. Multimodal analysis revealed that Fe (α) incorporated into the IML had a greater effect on joint strength than on the local IML properties: the presence of α promoted the formation of voids in the IML, deteriorating joint strength. FIB-SEM serial sectioning showed that Ni addition resulted in the formation of a dense IML with minimal α content, thereby suppressing void formation and improving joint strength. Local mechanical properties of the IML were unaffected by Ni, indicating that strength improvement was not due to changes in intrinsic mechanical properties. The findings suggest that Ni improved joint strength by modifying IML morphology rather than reducing its thickness, providing insights for designing robust Al/steel joints.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"255 ","pages":"Article 114236"},"PeriodicalIF":7.6,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144279325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0