Materials & Design最新文献_第9页

Dispersoid evolution in Al–Zn–Mg alloys by combined addition of Hf and Zr: A mechanistic approach 通过联合添加 Hf 和 Zr 实现 Al-Zn-Mg 合金中的分散演变：力学方法

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-11-01 DOI: 10.1016/j.matdes.2024.113366

V. Wessely , U. Töpfer , I. Basu , R.E. Schäublin , S. Pogatscher , P.J. Uggowitzer , J.F. Löffler

{"title":"Dispersoid evolution in Al–Zn–Mg alloys by combined addition of Hf and Zr: A mechanistic approach","authors":"V. Wessely , U. Töpfer , I. Basu , R.E. Schäublin , S. Pogatscher , P.J. Uggowitzer , J.F. Löffler","doi":"10.1016/j.matdes.2024.113366","DOIUrl":"10.1016/j.matdes.2024.113366","url":null,"abstract":"<div><div>Coherent Al<sub>3</sub>X-type L1<sub>2</sub>-structured dispersoids have the potential of effectively stabilizing the grain structure and increasing strength. This concept has been successfully demonstrated for non-hardenable and rapidly solidified Al alloys. In precipitation-hardened Al alloys, effective dispersoid addition requires both controlling their high-temperature stability and minimizing their impact on precipitation hardening. The current study focuses on dispersoid-modified AlZn5.0Mg1.2 alloys, which exhibit MgZn precipitation upon age-hardening and include less than 1 wt% of Zr and Hf for dispersoid formation. Heat treatments between 350 °C and 500 °C for varying times were applied to evaluate dispersoid formation, thermal stability and the related strengthening potential. The microstructure was assessed using transmission electron microscopy (TEM) and atom probe tomography (APT), and the mechanical response was evaluated by hardness testing. TEM after heating at 500 °C reveals Ostwald ripening for the dispersoids. APT results on the dispersoids reveal a core–shell structure development upon longer annealing times. The Zr–Hf-modified alloy exhibits a higher initial strength than the Zr-modified alloy but the latter displays greater strength retention even after prolonged exposure to 500 °C. This effect is attributed to a destabilization of the mixed Zr–Hf dispersoids that arises from lower enthalpic benefits of Al<sub>3</sub>Hf formation over Al<sub>3</sub>Zr.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113366"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of porosity on the tensile strength and Micromechanisms of laminated stitched C/C-SiC composites 孔隙率对层压缝合 C/C-SiC 复合材料拉伸强度和微观机理的影响

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-11-01 DOI: 10.1016/j.matdes.2024.113429

Zhuoyu Song , Kaiyin Xiao , Shijian Xiao , Kaifan Du , Zebei Mao , Tong Li , Bo Wang

{"title":"Effect of porosity on the tensile strength and Micromechanisms of laminated stitched C/C-SiC composites","authors":"Zhuoyu Song , Kaiyin Xiao , Shijian Xiao , Kaifan Du , Zebei Mao , Tong Li , Bo Wang","doi":"10.1016/j.matdes.2024.113429","DOIUrl":"10.1016/j.matdes.2024.113429","url":null,"abstract":"<div><div>This study examines how pore defects affect the tensile strength of laminated stitched carbon fiber reinforced carbon and silicon carbide (C/C-SiC) composites. Using computed tomography (CT) technology, internal characteristic parameters were obtained, and a representative volume cell contains pore (RVC-CP) defects was established. The homogenization method and strength estimation technique were applied to connect material properties from the microscopic to the mesoscopic scale. Progressive damage analysis of the representative volume cell (RVC) yielded tensile strength results within 2% of the average tensile test measurements, validating finite element models for strength prediction. The study found that pores create stress concentrations, leading to the failure of transverse and longitudinal fiber bundles, as well as the matrix. Additionally, it was observed that 8.9% pore content results in a 27.2% reduction in tensile strength compared to non-porous material. Based on these findings, empirical formulas for predicting tensile strength reduction due to pores are proposed. This paper presents a mesoscale computational model with pores that enhances the efficiency and accuracy of strength design for stitched C/C-SiC materials. In engineering, the model can be combined with non-destructive testing to quickly assess local strength reduction, offering valuable insights for designing C/C-SiC materials in aircraft and high-speed trains.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113429"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New insights into the kinetics of dynamic and post-dynamic softening in Alloy 718 engine disks 对合金 718 发动机盘动态软化和后动态软化动力学的新认识

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-11-01 DOI: 10.1016/j.matdes.2024.113423

E. Farabi , V.V. Rielli , F. Godor , C. Gruber , A. Stanojevic , B. Oberwinkler , S. Primig

{"title":"New insights into the kinetics of dynamic and post-dynamic softening in Alloy 718 engine disks","authors":"E. Farabi , V.V. Rielli , F. Godor , C. Gruber , A. Stanojevic , B. Oberwinkler , S. Primig","doi":"10.1016/j.matdes.2024.113423","DOIUrl":"10.1016/j.matdes.2024.113423","url":null,"abstract":"<div><div>The dynamic and post-dynamic recrystallisation (DRX and PDRX) kinetics of Alloy 718 are known to be dependent on the strain rate, deformation temperature, and the fraction of the δ-phase in the heterogeneous starting materials. Better control of these regimes is required for direct ageing (DA), to unlock superior high-temperature strength in next-generation aeroengine disks. There are gaps in the current understanding of the (post-)dynamic regime and its effect on γʹ and γʹʹ co-precipitation. Our aim is to reveal the critical parameters controlling the grain size and recrystallised fractions after thermo-mechanical processing (TMP) to model the post-dynamic microstructure evolution.</div><div>Two initial microstructures with different δ-phase fractions are subjected to 1.4 strain with 0.1–10 s<sup>−1</sup> strain rates to simulate industrial conditions. A short isothermal ost-deformation annealing is applied to assess the restoration behaviour. DRX is suppressed at strain rates >1 s<sup>−1</sup> at 950 °C due to limited time for dynamic restoration, while PDRX become predominant due to higher stored energy. At 1000°C, a fully recrystallised microstructure is achieved in all conditions. The presence of δ-phase increases DRX and PDRX rates and promotes microstructure stability. Our results are underpinned by models that predict PDRX and precipitation kinetics during DA.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113423"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microstructure evolution and hydrogen absorption characteristics of gradient-hydrogenated Ti-4.5Al-3V-2Mo-2Fe alloys 梯度氢化 Ti-4.5Al-3V-2Mo-2Fe 合金的微观结构演变和吸氢特性

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-11-01 DOI: 10.1016/j.matdes.2024.113436

Jinyuan Zhang , Shaosong Jiang , Yong Jia , Peng Peng , Yang Li , Shang Yang , Zhen Lu

{"title":"Microstructure evolution and hydrogen absorption characteristics of gradient-hydrogenated Ti-4.5Al-3V-2Mo-2Fe alloys","authors":"Jinyuan Zhang , Shaosong Jiang , Yong Jia , Peng Peng , Yang Li , Shang Yang , Zhen Lu","doi":"10.1016/j.matdes.2024.113436","DOIUrl":"10.1016/j.matdes.2024.113436","url":null,"abstract":"<div><div>Ti-4.5Al-3V-2Mo-2Fe rolled material is a dual-phase titanium alloy with an average grain size of less than 3 μm; its optimal superplastic forming temperature of 760 °C is at least 50 °C lower than the temperature required for diffusion bonding, making it challenging to carry out superplastic forming/diffusion bonding within a process window. The promotion of hydrogen on the low-temperature diffusion bonding of the alloy was verified through thermohydrogen processing, and the absorption characteristics of hydrogen in the alloy at various temperatures, holding times, and pressures were investigated. Subsequently, a mathematical model for achieving standardized hydrogen content was developed. X-ray polycrystalline diffractometer (XRD) analysis was utilized to preliminarily explore phase differences in samples with varying levels of hydrogen content. Furthermore, scanning electron microscopy (SEM), transmission electron microscopy (TEM), electron back scatter diffraction (EBSD) and time of flight secondary ion mass spectrometry (TOF-SIMS) were employed to analyze microstructure changes and hydrogen distribution in both the surface and core regions of the titanium alloy following hydrogenation, demonstrating its feasibility for surface hydrogenation treatment of titanium alloy sheets.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113436"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142651856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Balancing the strength and toughness in delignified bamboo through the changing of silicon composition 通过改变硅成分平衡脱木素竹材的强度和韧性

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-11-01 DOI: 10.1016/j.matdes.2024.113408

You Wang , Shuyu Jia , Zhe Ling , Jianfeng Ma , Xinxin Ma , Changhua Fang

{"title":"Balancing the strength and toughness in delignified bamboo through the changing of silicon composition","authors":"You Wang , Shuyu Jia , Zhe Ling , Jianfeng Ma , Xinxin Ma , Changhua Fang","doi":"10.1016/j.matdes.2024.113408","DOIUrl":"10.1016/j.matdes.2024.113408","url":null,"abstract":"<div><div>The partial removal of lignin from bamboo materials, a prevalent method to soften the material for plastic forming. It increases bending toughness and improves forming quality, albeit at the expense of load-bearing capacity. This study employs an innovative approach using deep eutectic solvent pretreatment on bamboo green strips (BGS) to establish a balance between strength and toughness, resulting in a significant enhancement of the elastic modulus. The mechanical properties of the DES-treated BGS displayed notable improvements compared to bamboo timber strips (BTS) and bamboo yellow strips (BYS), which either showed no enhancement or suffered degradation after extended treatment durations. Notably, BGS treated for one hour exhibited increases of 8.22 % in flexural toughness and 33.45 % in elastic modulus, while strength diminished by a mere 5.72 %. Concurrently, its porosity increased by 29.36 %, predominantly in the mesopore range. In addition, the crystallinity of the treated BGS increased, whereas the grain size decreased. Silicon-aluminum compounds form on the outer surface of BGS, along with an increase in silicon oxide content, contributed to the observed improvements in stiffness and toughness. These works suggest a novel method for balancing modulus and strength of bamboo structural units, with potential applications in architecture, furniture and transportation sectors.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113408"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-physics coupled simulation and experimental investigation of alternating stray current corrosion of buried gas pipeline adjacent to rail transit system 轨道交通系统附近埋地燃气管道交变杂散电流腐蚀的多物理场耦合模拟与实验研究

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-11-01 DOI: 10.1016/j.matdes.2024.113394

Chengtao Wang , Shaoyi Xu , Wei Li , Yuqiao Wang , Guanyi Shen , Shuchen Wang

{"title":"Multi-physics coupled simulation and experimental investigation of alternating stray current corrosion of buried gas pipeline adjacent to rail transit system","authors":"Chengtao Wang , Shaoyi Xu , Wei Li , Yuqiao Wang , Guanyi Shen , Shuchen Wang","doi":"10.1016/j.matdes.2024.113394","DOIUrl":"10.1016/j.matdes.2024.113394","url":null,"abstract":"<div><div>As the gradual emergence of alternating current (AC) electrified rail transit system in urban areas, buried gas pipeline adjacent to the system will be seriously corroded by induced alternating stray current. These buried gas pipelines are at serious risk of electrochemical corrosion, which leads to safety and environmental threaten. In order to study the distribution of alternating stray current corrosion on pipeline surface on a larger spatial scale, this paper conducted numerical simulation and experimental validation of alternating stray current corrosion of buried gas pipeline. In the numerical simulation model, coupling between different physical fields are realized through the relationship between current density of pipe-to-soil interface, electrolyte, and electrodes. Proposed numerical method based on coupled multi-physics in this paper are in good agreement with experimental results under different influencing factors. A novel evaluation index was proposed to assess the corrosion risk within different zones on the pipeline surface. Results show that corrosion distribution is greatly influenced by spatial interaction between buried pipeline and rail transit system including crossing angle and parallel distance. Besides, alternating stray current corrosion on buried gas pipeline are proved to be both affected by dynamic characteristics due to AC fluctuation and operation mode of locomotive.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113394"},"PeriodicalIF":7.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microstructural evolution and 1500 °C oxidation resistance of Mo(Al,Si)2 fabricated via an innovative two-step SHS-SPS technique 通过创新的两步 SHS-SPS 技术制造的 Mo(Al,Si)2 的微结构演化和 1500 °C 抗氧化性

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-10-24 DOI: 10.1016/j.matdes.2024.113397

Nana Zhu , Lu Zhu , Baojing Zhang , Peizhong Feng , Shiheng Li , Philipp V. Kiryukhantsev-Korneev , Evgeny A. Levashov , Xuanru Ren , Xiaohong Wang

{"title":"Microstructural evolution and 1500 °C oxidation resistance of Mo(Al,Si)2 fabricated via an innovative two-step SHS-SPS technique","authors":"Nana Zhu , Lu Zhu , Baojing Zhang , Peizhong Feng , Shiheng Li , Philipp V. Kiryukhantsev-Korneev , Evgeny A. Levashov , Xuanru Ren , Xiaohong Wang","doi":"10.1016/j.matdes.2024.113397","DOIUrl":"10.1016/j.matdes.2024.113397","url":null,"abstract":"<div><div>An innovative two-step approach of self-propagating high-temperature synthesis (SHS) and spark plasma sintering (SPS) was developed to rapidly fabricate MoSi<sub>2</sub> and Mo(Al,Si)<sub>2</sub> ceramics for high-temperature anti-oxidation applications. The SHS process predominantly promoted the synthesis of high-purity and high-yield MoSi<sub>2</sub> and Mo(Si,Al)<sub>2</sub> phases in the alloyed powders. Subsequently, dense and crack-free MoSi<sub>2</sub> and Mo(Al,Si)<sub>2</sub> ceramics were produced using SPS. 1500 °C oxidation tests of the ceramics (100 h) revealed the formation of a protective SiO<sub>2</sub> oxide layer on the surface of MoSi<sub>2</sub> ceramics, while an Al-Si-O composite glassy oxide layer formed on Mo(Si,Al)<sub>2</sub> ceramics, which exhibited better thermal stability and lower oxygen permeability compared to the single SiO<sub>2</sub> oxide layer. However, an excessive Al content (>0.05 at.%) compromised the oxidation resistance due to the emergence of a Si-depleted Mo<sub>5</sub>(Si,Al)<sub>3</sub> layer with inferior oxidation resistance, which was caused by the high-temperature diffusion of Si. Therefore, via this novel two-step SHS-SPS technique compact and crack-free Mo(Si,Al)<sub>2</sub> ceramics can be rapidly synthesized at high temperatures. When trace amount of Al was added (0.05 at.%), Mo(Si<sub>0.95</sub>Al<sub>0.05</sub>)<sub>2</sub> showed optimum high-temperature oxidation resistance.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113397"},"PeriodicalIF":7.6,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mesenchymal stem cells derived extracellular vesicles modified PLGA electrospinning nanofibrous scaffolds for corneal and retinal repair 用于角膜和视网膜修复的间充质干细胞衍生细胞外囊泡修饰聚乳酸（PLGA）电纺纳米纤维支架

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-10-24 DOI: 10.1016/j.matdes.2024.113389

Jingfan Wang , Xingxing Wang , Xiying Ma , Ting Pan , Qiang Fu , Xinsheng Li , Jie Lei , Yan Wu , Changlin Xu , Qinyuan Gu , Yuanyuan Fan , Tianhao Xiao , Zhangqi Feng , Ping Xie , Zizhong Hu

{"title":"Mesenchymal stem cells derived extracellular vesicles modified PLGA electrospinning nanofibrous scaffolds for corneal and retinal repair","authors":"Jingfan Wang , Xingxing Wang , Xiying Ma , Ting Pan , Qiang Fu , Xinsheng Li , Jie Lei , Yan Wu , Changlin Xu , Qinyuan Gu , Yuanyuan Fan , Tianhao Xiao , Zhangqi Feng , Ping Xie , Zizhong Hu","doi":"10.1016/j.matdes.2024.113389","DOIUrl":"10.1016/j.matdes.2024.113389","url":null,"abstract":"<div><div>Tissue self-renewal is crucial for ocular diseases such as corneal damage and retinal holes. In this study, a novel Poly (lactic-co-glycolic acid) (PLGA) electrospinning nanofibrous scaffold (PLGA<sup>ENS</sup>), loaded with mesenchymal stem cells-derived extracellular vesicles (MSC-EVs), was developed to accelerate the healing of the cornea and retina. <em>In-vitro</em> experiments confirmed the supportive properties of PLGA<sup>ENS</sup>, demonstrating its ability to promote cellular proliferation, migration, and extension. In the rat corneal alkali burn model and rabbit retinal hole model, MSC-EVs modified PLGA<sup>ENS</sup> (PLGA<sup>MSC-EVs</sup>) accelerated the restoration of the corneal epithelium and stroma, as well as the closure of retinal holes. Additionally, miR-21-5p was identified as being enriched in MSC-EVs. Mechanistically, miR-21-5p suppressed scar formation by targeting the programmed cell death protein 4 (PDCD4) gene, reducing fibrosis and the expression of collagen-related genes, which helped maintain corneal transparency and retinal integrity. Overall, these findings underscored the potential of PLGA<sup>MSC-EVs</sup> in promoting ocular wound healing and suggested a promising new therapeutic strategy for the clinical treatment of corneal damage and retinal holes.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113389"},"PeriodicalIF":7.6,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bayesian-neural-network accelerated design of multispectral-compatible camouflage layer with wide-band microwave absorption, customized infrared emission and visible transparency 贝叶斯神经网络加速设计具有宽带微波吸收、定制红外发射和可见光透明性的多光谱兼容伪装层

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-10-24 DOI: 10.1016/j.matdes.2024.113400

Hui-Ting Sun , Jun Wang , Jie Yang , Rui-Chao Zhu , Jie Zhang , Sai Sui , Zhao-Tang Liu , Zun-Tian Chu , Yi-Na Cui , Shao-Bo Qu , Jia-Fu Wang

{"title":"Bayesian-neural-network accelerated design of multispectral-compatible camouflage layer with wide-band microwave absorption, customized infrared emission and visible transparency","authors":"Hui-Ting Sun , Jun Wang , Jie Yang , Rui-Chao Zhu , Jie Zhang , Sai Sui , Zhao-Tang Liu , Zun-Tian Chu , Yi-Na Cui , Shao-Bo Qu , Jia-Fu Wang","doi":"10.1016/j.matdes.2024.113400","DOIUrl":"10.1016/j.matdes.2024.113400","url":null,"abstract":"<div><div>Metasurfaces with customizable multi-spectrum compatibility have attracted a great deal of attention due to the increasing applications of stealth and camouflage. Compared with single-spectrum and fixed-scene camouflage metasurfaces, a camouflage metasurface with the designability and spectral-independence can adapt to more complex environments. However, this drastically increases the design complexity and time cost of metasurfaces. Here, we propose a method to design multispectral compatible function layer of camouflage which can achieve customizable wideband microwave absorption, visible transparency and selective infrared emission, simultaneously. The design of the camouflage layer is optimized and accelerated by Bayesian-neural network, which can be implemented based on a very limited amount of prior data and can greatly reduce the design complexity and time. To verify our method, an optical-transparent metasurface with digital infrared camouflage and low backward scattering was designed and fabricated. The simulation and experimental results well demonstrate the performance of multispectral compatible camouflage of the metasurface. We further explore the angular stability of the camouflage layer to the incident angle varying from 0 to 60° at microwaves. Our proposed design scheme provides a novel method to design spectrum-individual and devisable metasurfaces, which can be applied to camouflage in complex spectrum background.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113400"},"PeriodicalIF":7.6,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-drug loaded manganese dioxide nanoparticles coated with bacterial outer-membrane vesicles for chemo-immunotherapy in lung cancer 涂有细菌外膜囊泡的双药负载二氧化锰纳米粒子用于肺癌化疗免疫疗法

IF 7.6 2区材料科学

Materials & Design Pub Date : 2024-10-23 DOI: 10.1016/j.matdes.2024.113406

Lixu Xie , Shichang Jiang , Changwen Zhang , Miao Liu , Yiqing Qu

{"title":"Dual-drug loaded manganese dioxide nanoparticles coated with bacterial outer-membrane vesicles for chemo-immunotherapy in lung cancer","authors":"Lixu Xie , Shichang Jiang , Changwen Zhang , Miao Liu , Yiqing Qu","doi":"10.1016/j.matdes.2024.113406","DOIUrl":"10.1016/j.matdes.2024.113406","url":null,"abstract":"<div><div>Lung cancer is the most leading cause of cancer death. Traditional chemotherapy has unavoidable drawbacks of nonspecific tumor targeting, high toxicity, and poor therapeutic efficiency. Nanocarriers can achieve accurate delivery and reduce adverse reactions of drugs, which have received extensive attention. In this work, hollow manganese dioxide (HMnO<sub>2</sub>) nanoparticle (NP) that is highly responsive to tumor microenvironment, was simultaneously loaded with paclitaxel (PTX), a chemotherapy drug, and imiquimod (R837), a toll-like receptor 7 agonist. Those NPs were then coated with bacterial outer-membrane vesicles (OMVs-HMnO<sub>2</sub>@PTX + R837 NPs), whose surface proteins could act as tumor-specific antigens. The obtained nanovaccine inherited superior tumor-targeting capacity of OMVs and promoted retention in tumors. As a result, intravenous injection of the nanovaccine led to remarkable tumor growth inhibition. Furthermore, we found that the nanovaccine effectively boosted dendritic cells maturation and increased cytotoxic T lymphocytes infiltration. Taken together, these results demonstrated the great potential in applying OMVs-enveloped nano-activator in cancer chemo-immunotherapy.</div></div>","PeriodicalId":383,"journal":{"name":"Materials & Design","volume":"247 ","pages":"Article 113406"},"PeriodicalIF":7.6,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142535617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0