Clocks & Sleep最新文献_第8页

34th Annual Meeting of the Society for Light Treatment and Biological Rhythms (SLTBR), 30 May-1 June, Lausanne, Switzerland. 第34届光处理与生物节律学会年会，5月30日至6月1日，瑞士洛桑。

IF 2.1

Clocks & Sleep Pub Date : 2023-08-24 DOI: 10.3390/clockssleep5030031

Christian Cajochen

引用次数: 0

Social Deprivation and Ethnicity Are Associated with More Problematic Sleep in Middle-Aged and Older Adults. 社会剥夺和种族与中老年睡眠问题有关

IF 3.1

Clocks & Sleep Pub Date : 2023-08-07 DOI: 10.3390/clockssleep5030030

John A Groeger, Piril Hepsomali

{"title":"Social Deprivation and Ethnicity Are Associated with More Problematic Sleep in Middle-Aged and Older Adults.","authors":"John A Groeger, Piril Hepsomali","doi":"10.3390/clockssleep5030030","DOIUrl":"https://doi.org/10.3390/clockssleep5030030","url":null,"abstract":"Objectives: We test the hypothesis that the incidence of sleep problems is influenced by socio-demographic variables, particularly social deprivation and ethnicity. Methods: Self-reports of sleep duration and sleep difficulties (waking in the night, sleeping in the day, difficulty waking and snoring), personal wealth (household income, property-owning, etc.), ethnic group, employment, education, as well as post-code-based Townsend Social Deprivation, were extracted from UK Biobank's cohort of c500,000 British-domiciled adults (40-70 years). Analyses contrasted the incidence of different sleep problems and a composite measure of these (the Problematic Sleep Index) across groups. Results: Almost one-third of participants reported sleeping shorter (24.7%), or longer (7.7%) than age-corrected recommended sleep durations. The incidence of shorter or longer sleep increased with social deprivation and varied with ethnicity. Snoring, waking during the night, finding it difficult to get up in the morning and sleeping in the daytime were subject to similar effects. The Problematic Sleep Index showed being younger, male, employed, home-owning, having a higher household income, having a higher level of educational achievement, and time in education were all associated with better sleep, as was living in a more affluent area and being White. Conclusions: Sleep problems in Britain show a social gradient, independently of a range of other demographic and social influences, suggesting that sleep quality differs with and between ethnic groups. These sleep inequalities suggest that the protective and recuperative effects of sleep are disproportionately distributed across society and should encourage us to consider the potential benefits of community-specific sleep interventions.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 3","pages":"399-413"},"PeriodicalIF":3.1,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10443366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10114353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of Evidence for the Involvement of the Circadian Clock Genes into Malignant Transformation of Thyroid Tissue. 生物钟基因参与甲状腺组织恶性转化的证据综述。

IF 3.1

Clocks & Sleep Pub Date : 2023-07-13 DOI: 10.3390/clockssleep5030029

Arcady A Putilov, Elena V Budkevich, Roman O Budkevich

{"title":"A Review of Evidence for the Involvement of the Circadian Clock Genes into Malignant Transformation of Thyroid Tissue.","authors":"Arcady A Putilov, Elena V Budkevich, Roman O Budkevich","doi":"10.3390/clockssleep5030029","DOIUrl":"https://doi.org/10.3390/clockssleep5030029","url":null,"abstract":"(1) Background: In 2013, the results of a pioneer study on abnormalities in the levels and circadian rhythmicity of expression of circadian clock genes in cancerous thyroid nodules was published. In the following years, new findings suggesting the involvement of circadian clockwork dysfunction into malignant transformation of thyroid tissue were gradually accumulating. This systematic review provides an update on existing evidence regarding the association of these genes with thyroid tumorigenesis. (2) Methods: Two bibliographic databases (Scopus and PubMed) were searched for articles from inception to 20 March 2023. The reference lists of previously published (nonsystematic) reviews were also hand-searched for additional relevant studies. (3) Results: Nine studies published between 2013 and 2022 were selected. In total, 9 of 12 tested genes were found to be either up- or downregulated. The list of such genes includes all families of core circadian clock genes that are the key components of three transcriptional-translational feedback loops of the circadian clock mechanism (BMAL1, CLOCK, NPAS2, RORα, REV-ERBα, PERs, CRYs, and DECs). (4) Conclusions: Examination of abnormalities in the levels and circadian rhythmicity of expression of circadian clock genes in thyroid tissue can help to reduce the rate of inadequate differential preoperative diagnosis for thyroid carcinoma.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 3","pages":"384-398"},"PeriodicalIF":3.1,"publicationDate":"2023-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9872242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Better Mental Health and Sleep under Behavioral Restrictions Due to COVID-19 in Japanese University Students: A Cross-Sectional Survey. 日本大学生在COVID-19行为限制下更好的心理健康和睡眠:一项横断面调查。

IF 3.1

Clocks & Sleep Pub Date : 2023-07-05 DOI: 10.3390/clockssleep5030028

Hideki Shimamoto, Masataka Suwa, Hiroyoshi Adachi, Manabu Adachi, Koh Mizuno

{"title":"Better Mental Health and Sleep under Behavioral Restrictions Due to COVID-19 in Japanese University Students: A Cross-Sectional Survey.","authors":"Hideki Shimamoto, Masataka Suwa, Hiroyoshi Adachi, Manabu Adachi, Koh Mizuno","doi":"10.3390/clockssleep5030028","DOIUrl":"https://doi.org/10.3390/clockssleep5030028","url":null,"abstract":"Coronavirus disease (COVID-19) is a global pandemic, which is not only a severe public health issue but also significantly impacts the physical activity, sleep habits, and mental health of university students. Thus, we examined the association between behavioral restrictions due to COVID-19 and sleep patterns and mental health in first-year Japanese university students. Four hundred and twenty-two students (253 males and 169 females; age, 18.7 ± 1.0 years) participated in our questionnaire study. Under the behavioral restrictions due to COVID-19, 193 students (127 males and 66 females) responded to the questionnaire online from home. The participants did not visit the university during the survey period. The data acquired the year before the COVID-19 pandemic (2018 and 2019) were used as control data (126 males and 103 females). The questionnaire consisted of four sections: (1) demographic and lifestyle variables, (2) the Pittsburgh Sleep Quality Index, (3) the Japanese version of the Epworth Sleepiness Scale, and (4) the Patient Health Questionnaire-9. Our data revealed that self-restraint due to COVID-19 was associated with better sleep and mental health. In addition, mental health was independent of sleep, while sleep was related to mental health. These differences were more pronounced in male than in female students. This finding could be due to physical activity at night, part-time work, and long commuting times during the pre-pandemic period.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 3","pages":"373-383"},"PeriodicalIF":3.1,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9872245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Time Spent Outdoors and Associations with Sleep, Optimism, Happiness and Health before and during the COVID-19 Pandemic in Austria. 在奥地利COVID-19大流行之前和期间，户外活动时间与睡眠、乐观、幸福和健康的关系

IF 3.1

Clocks & Sleep Pub Date : 2023-06-25 DOI: 10.3390/clockssleep5030027

Simon Schamilow, Isabel Santonja, Jakob Weitzer, Susanne Strohmaier, Gerhard Klösch, Stefan Seidel, Eva Schernhammer, Kyriaki Papantoniou

{"title":"Time Spent Outdoors and Associations with Sleep, Optimism, Happiness and Health before and during the COVID-19 Pandemic in Austria.","authors":"Simon Schamilow, Isabel Santonja, Jakob Weitzer, Susanne Strohmaier, Gerhard Klösch, Stefan Seidel, Eva Schernhammer, Kyriaki Papantoniou","doi":"10.3390/clockssleep5030027","DOIUrl":"https://doi.org/10.3390/clockssleep5030027","url":null,"abstract":"Social restriction measures (SRM) implemented during the COVID-19 pandemic led to a reduction in time spent outdoors (TSO). The aim of this study was to describe TSO and evaluate its association with sleep outcomes, optimism, happiness and health-status before and during SRM. Two online surveys were conducted in 2017 (N = 1004) and 2020, during SRM (N = 1010), in samples representative of the age, sex and region of the Austrian population. Information on the duration of TSO, sleep, optimism, happiness and health-status was collected. Multivariable-adjusted logistic regression models were used to study the association of TSO with chronic insomnia, short sleep, late chronotype, optimism, happiness and self-rated health-status. The mean TSO was 3.6 h (SD: 2.18) in 2017 and 2.6 h (SD: 1.87) during times of SRM. Men and participants who were older, married or in a partnership and lived in a rural area reported longer TSO. Participants who spent less time outdoors were more likely to report short sleep or a late chronotype in both surveys and, in 2020, also chronic insomnia. Less TSO was associated with lower happiness and optimism levels and poor health-status. Our findings suggest that TSO may be a protective factor for sleep, mood and health, particularly during stressful and uncertain times.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 3","pages":"358-372"},"PeriodicalIF":3.1,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9877565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Timing of the Melatonin Onset and Phase Angle to Sleep Onset in Older Adults after Uncontrolled vs. Controlled Lighting Conditions. 老年人在不受控制与受控制的照明条件下褪黑激素的起始时间和与睡眠起始时间的相位角。

IF 2.1

Clocks & Sleep Pub Date : 2023-06-25 DOI: 10.3390/clockssleep5030026

Arturo Arrona-Palacios, Jung-Hie Lee, Charles A Czeisler, Jeanne F Duffy

{"title":"The Timing of the Melatonin Onset and Phase Angle to Sleep Onset in Older Adults after Uncontrolled vs. Controlled Lighting Conditions.","authors":"Arturo Arrona-Palacios, Jung-Hie Lee, Charles A Czeisler, Jeanne F Duffy","doi":"10.3390/clockssleep5030026","DOIUrl":"10.3390/clockssleep5030026","url":null,"abstract":"The main aim of this study was to explore how melatonin onset timing and phase angle to bedtime in healthy older adults are impacted by prior light exposure. A total of 13 healthy older (ages 56-74) individuals were studied on two successive evenings. Prior to the first evening, the participants were in self-selected lighting conditions for the first 4-6 h of the day and then were in dim light (3 lux) until their scheduled bedtime. On the second day, individuals from Project A remained in the dim lighting conditions throughout the entire day but those in Project B were in more typical indoor lighting (~90 lux) throughout the day. On both evenings, hourly blood samples were collected and assayed for melatonin, and melatonin onset timing and phase angle to sleep onset was determined. Overall, melatonin onset was earlier and the phase angle was larger on Night 1 than on Night 2. In Project A there was no significant difference between melatonin onset on night 1 vs. night 2. However, in Project B melatonin onset was significantly later on Night 2 (in typical indoor lighting) than on Night 1 (in dim lighting). Our results suggest that in older people, uncontrolled bright light early in the day did not impact the timing of dim light melatonin onset (DLMO) when assessed later that same evening. However, in older adults, exposure to ordinary room light during melatonin phase assessment appeared to suppress melatonin, leading to a later observed time of melatonin onset, as has been reported previously for young adults.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 3","pages":"350-357"},"PeriodicalIF":2.1,"publicationDate":"2023-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10366720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9875448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Burden of Comorbidities in Obstructive Sleep Apnea and the Pathophysiologic Mechanisms and Effects of CPAP. 阻塞性睡眠呼吸暂停合并症的负担及CPAP的病理生理机制和作用。

IF 3.1

Clocks & Sleep Pub Date : 2023-06-19 DOI: 10.3390/clockssleep5020025

Victoria Sircu, Silvia-Iaroslava Colesnic, Serghei Covantsev, Olga Corlateanu, Anna Sukhotko, Cristian Popovici, Alexandru Corlateanu

{"title":"The Burden of Comorbidities in Obstructive Sleep Apnea and the Pathophysiologic Mechanisms and Effects of CPAP.","authors":"Victoria Sircu, Silvia-Iaroslava Colesnic, Serghei Covantsev, Olga Corlateanu, Anna Sukhotko, Cristian Popovici, Alexandru Corlateanu","doi":"10.3390/clockssleep5020025","DOIUrl":"https://doi.org/10.3390/clockssleep5020025","url":null,"abstract":"Micro-arousals and the repeated desaturation of oxyhemoglobin, which are typical in obstructive sleep apnea syndrome (OSAS), have adverse effects on the health of patients, leading to a wide range of complications such as cardiovascular (arterial hypertension, pulmonary hypertension, chronic heart failure, arrhythmias, myocardial infarction), cerebrovascular (strokes), metabolic (insulin resistance, obesity, diabetes mellitus, metabolic syndrome), gastrointestinal (non-alcoholic liver disease), urinary (chronic renal failure), and neuropsychiatric complications as well as a wide range of malignancies. These, in turn, have multilateral effects on familial, occupational, and social life, as well as increasing the risks of road traffic accidents and accidents at the workplace. Awareness, timely screening, and the prevention of complications play important roles in diagnosing and treating comorbid conditions. This review focuses on comorbidities in OSAS and the effect of Continuous Positive Airway Pressure (CPAP) therapy on their prognoses.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 2","pages":"333-349"},"PeriodicalIF":3.1,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9721392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Mindfulness, Subjective Cognitive Functioning, Sleep Timing and Time Expansion during COVID-19 Lockdown: A Longitudinal Study in Italy. 正念、主观认知功能、睡眠时间和时间扩张在COVID-19封锁期间:意大利的一项纵向研究。

IF 3.1

Clocks & Sleep Pub Date : 2023-05-30 DOI: 10.3390/clockssleep5020024

Marco Fabbri

{"title":"Mindfulness, Subjective Cognitive Functioning, Sleep Timing and Time Expansion during COVID-19 Lockdown: A Longitudinal Study in Italy.","authors":"Marco Fabbri","doi":"10.3390/clockssleep5020024","DOIUrl":"https://doi.org/10.3390/clockssleep5020024","url":null,"abstract":"During the COVID-19 lockdown, a distortion of time passage has been widely reported in association with a change in daily rhythm. However, several variables related to these changes have not been considered. The purpose of the present study was to assess the changes in dispositional mindfulness, time experience, sleep timing and subjective memory functioning. A longitudinal study was conducted on 39 Italian adults (53.85% males; 35.03 ± 14.02 years) assessing mindfulness, ad hoc questions of sleep habits during workdays and free days, chronotypes, subjective time experience, and memory functioning before (December 2019-March 2020) and during (April 2020-May 2020) the first Italian COVID-19 lockdown. Participants reported delayed sleep timing, a slowdown in the perception of the present time, a decrease of time pressure, and an increase in the feeling of time expansion/boredom. In addition to correlations between mindfulness, memory functioning, and subjective sleep duration during workdays, a mediation model showed that changes in the dispositional mindfulness determined a delay of bedtime during workdays through the mediation effect of increased feeling of time expansion/boredom. This finding highlighted the role of mindfulness in reducing the feeling of time expansion/boredom for regulating the sleep timing. The theoretical and practical implications of the findings are discussed.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 2","pages":"313-332"},"PeriodicalIF":3.1,"publicationDate":"2023-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10297565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9721393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Devastating Effects of Sleep Deprivation on Memory: Lessons from Rodent Models. 睡眠剥夺对记忆的破坏性影响:来自啮齿动物模型的教训。

IF 3.1

Clocks & Sleep Pub Date : 2023-05-15 DOI: 10.3390/clockssleep5020022

Pinqiu Chen, Weikang Ban, Wenyan Wang, Yuyang You, Zhihong Yang

引用次数: 3

The Relationship between Sleep, Chronotype, and Dental Caries-A Narrative Review. 睡眠、睡眠类型和龋齿之间的关系——一个叙述性的回顾。

IF 3.1

Clocks & Sleep Pub Date : 2023-05-15 DOI: 10.3390/clockssleep5020023

Anamaria Kurtović, Jasminka Talapko, Sanja Bekić, Ivana Škrlec

{"title":"The Relationship between Sleep, Chronotype, and Dental Caries-A Narrative Review.","authors":"Anamaria Kurtović, Jasminka Talapko, Sanja Bekić, Ivana Škrlec","doi":"10.3390/clockssleep5020023","DOIUrl":"https://doi.org/10.3390/clockssleep5020023","url":null,"abstract":"This article provides an overview of how sleep and circadian rhythm disturbances mutually influence the occurrence of dental caries and how it is possible to reduce the risk of circadian rhythm disturbances, sleep, and associated adverse effects. Dental caries is a global problem worldwide that contributes to sociological limitations. Numerous factors influence the occurrence of dental caries, from socioeconomic factors to cariogenic bacteria, dietary habits, and oral hygiene. However, sleep disorders and circadian rhythm disturbances represent a new approach in the fight against the increasing prevalence of dental caries worldwide. Bacteria in the oral cavity and the oral microbiome are mainly responsible for the development of caries, and saliva plays an important role in their regulation. The circadian rhythm regulates numerous physiological functions, including sleep and saliva production. Disturbances in sleep and circadian rhythms affect saliva production, which impacts the development of dental caries, as saliva is necessary for regulating and maintaining oral health, especially for controlling oral infections. A person's preference for a particular time of day depends on the circadian rhythm called chronotype. Individuals with an evening chronotype have a less healthy lifestyle that can lead to a higher caries risk than individuals with a morning chronotype. Because circadian rhythms are critical to maintaining sleep homeostasis and oral health, sleep disturbances can disrupt circadian rhythms and lead to a vicious cycle.","PeriodicalId":33568,"journal":{"name":"Clocks & Sleep","volume":"5 2","pages":"295-312"},"PeriodicalIF":3.1,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10204555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9515231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0