Advances in Colloid and Interface Science最新文献

{"title":"Supramolecular self-assembly of enzymatically hydrolyzed food protein polypeptides: Versatile architecture for enhancing the intestinal absorption of natural bioactive compounds","authors":"Jin Feng ,&nbsp;Songbai Liu ,&nbsp;Wuyang Huang ,&nbsp;Ying Li","doi":"10.1016/j.cis.2025.103734","DOIUrl":"10.1016/j.cis.2025.103734","url":null,"abstract":"<div><div>Nanotechnology has been widely utilized to enhance the intestinal absorption of natural bioactive compounds (BCs). However, the complicated and dynamic environment in the gastrointestinal tract (GIT) – characterized by digestive enzymes, mucus matrix, epithelial cell layer, and extensive metabolic activity – presents notable challenges to the oral delivery of BCs. To address these limitations, nanocarriers based on enzymatically hydrolyzed food protein polypeptides (EH-FPPs) have been developed, which exhibit high biocompatibility, loading capacity, and capacity to overcome different absorption barriers. This review provides a comprehensive summary of recent advancements in EH-FPP-assembled nanocarriers, including their self-assembly mechanisms, supramolecular structures, and loading approaches for natural BCs. Besides, it elucidates the how these nanocarriers enhance the intestinal absorption of BCs from the perspectives of controlled release, mucus penetration, transcytosis, and paracellular transport. Furthermore, it critically assesses the role of these nanocarriers in improving the overall bioavailability and therapeutic efficacy of encapsulated BCs, while also addressing their current limitations and future research directions. This review seeks to elucidate the complex relationships between the self-assembly process, multi-scale structure, and GIT fate of EH-FPP-based vehicles, which highlights their potential as advanced BC delivery systems for precision nutrition and individualized health.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103734"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145760481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in molecular simulations of clays: From slit pore to clay matrix nanopore","authors":"Jiangtao Pang ,&nbsp;Qi Li ,&nbsp;Yunfeng Liang ,&nbsp;Takeshi Tsuji","doi":"10.1016/j.cis.2025.103767","DOIUrl":"10.1016/j.cis.2025.103767","url":null,"abstract":"<div><div>Clays play a critical role in natural and engineered systems due to their unique layered structures, surface reactivity, and capacity to regulate fluid and solute behavior. From carbon sequestration and contaminant containment to enhanced oil recovery and subsurface energy storage, understanding clay–fluid interactions is essential for predicting system performance of sediment complex. However, most atomistic studies have relied on idealized infinite-sheet models, which overlook critical features such as edge terminations, finite particle size, and morphological heterogeneity—elements that dominate in real clay aggregates. This review addresses this knowledge gap by synthesizing recent advances in finite-particle modeling, which capture edge chemistry, stacking disorder, and confinement-driven transport dynamics. We examine the structural construction of finite clay models, discuss key force field developments, and highlight how finite systems alter hydration, ion adsorption, and molecular diffusion. Particular focus is placed on the emergence of anisotropic pore geometries, dynamic confinement effects, and size-dependent mechanical behavior. By bridging infinite and finite modeling paradigms, this review aspires to contribute to on-going efforts in modeling, experimentation, and multiscale integration toward more representative depictions of clay behavior across diverse applications.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103767"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145881621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Programming superlyophobic interfaces via fine-tuning surface chemistry: From controllable fabrication to intelligent manipulation","authors":"Lu Tie,&nbsp;Ran Lei,&nbsp;Dandan Xi","doi":"10.1016/j.cis.2025.103765","DOIUrl":"10.1016/j.cis.2025.103765","url":null,"abstract":"<div><div>Recent advances have expanded superwetting system from single to multiple superlyophobicity, enabling diverse superlyophobic interfaces. However, current research lacks a comprehensive understanding of how surface chemistry governs superlyophobic properties-knowledge that is essential for rationally designing superwetting behaviors. This article highlights design principles of fine-tuning surface chemistry, fabrication strategies and multifunctional applications of diverse superlyophobic interfaces, emphasizing how lyophobic and lyophilic components of surface govern single and multiple superlyophobicity. Based on surface thermodynamics, the preparation methods, regulation strategies and underlying mechanism for various types of superlyophobic interfaces are systematically analyzed. Furthermore, the article distills representative applications that align with various single and multiple superlyophobic interfaces under complex environmental conditions and functional requirements, offering a foundational framework for their practical utilization. By establishing surface chemistry design criteria, we provide insights into the rational control of single or multiple superlyophobicity and the integration of additional functionalities, thereby enabling the exploration of novel wetting states and multifunctional interfaces. Finally, we outline future challenges and emerging trends, including advances in multiple superlyophobic mechanisms, innovative fabrication techniques, and next-generation performance enhancements for these interfaces.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103765"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145881620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrokinetic transport in saturated and unsaturated porous media: A pore-scale view","authors":"Yunfan Huang,&nbsp;Zhiguo Tian,&nbsp;Hangyu Chen,&nbsp;Wei Liu,&nbsp;Moran Wang","doi":"10.1016/j.cis.2025.103755","DOIUrl":"10.1016/j.cis.2025.103755","url":null,"abstract":"<div><div>Electrokinetic transports in porous media play a crucial role in diverse applications such as geophysical exploration, nuclear waste disposal, water desalination, soil and groundwater remediation, low-salinity waterflooding, and ionic battery operation. This review systematically examines electrokinetic mechanisms in single-phase and multiphase flows in porous media, with a special focus on multiscale and multiphysico-chemical coupling effects. After briefly introducing fundamental theories on microscale electrokinetic transports, we highlight the impact of nanoscale confinement and geometric regulation at first on single-phase electrokinetic flows and ion transport. Next, we discuss the influences of non-uniform ionic concentration and temperature fields on electrokinetic transports, encompassing the impact of surface chemical reactions via charge regulation and reactive transports, and thermodiffusion effects. Furthermore, we provide a concise overview of the current understanding of electrokinetics in multiphase flows, including interfacial charging, wettability alteration, and electrokinetic multiphase dynamics. Finally, we try to outline future research directions, addressing statistics-based theories, multiscale simulations, and advanced experimental designs for electrokinetic transports in porous media.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103755"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lignin nanoparticles as Pickering stabilizers: Emulsion engineering through physicochemical design and meta-analysis","authors":"Ronald Marquez ,&nbsp;Roberto J. Aguado ,&nbsp;Quim Tarrés ,&nbsp;Laura Tolosa ,&nbsp;Blaise L. Tardy ,&nbsp;Orlando J. Rojas ,&nbsp;Martin A. Hubbe ,&nbsp;Marc Delgado-Aguilar","doi":"10.1016/j.cis.2025.103752","DOIUrl":"10.1016/j.cis.2025.103752","url":null,"abstract":"<div><div>This review systematically examines the principal physicochemical parameters that govern the formation, stability, and properties of Pickering emulsions stabilized by lignin nanoparticles (LNPs). We consider the role of particle size, charge and concentration, oil volume fraction, as well as emulsification variables (pH and shearing method). We demonstrate the broad applicability of fundamental physical chemistry principles in explaining the long-term stability of LNP-stabilized Pickering emulsions. LNPs with diameters of 25–50 nm, at concentrations between 0.2 and 2 wt%, generally yield emulsions stable for over six months. This suggests that rapid interfacial coverage by smaller particles, facilitated by high-energy emulsification, is critical for preventing initial coalescence. Such emulsions are generally more stable at acidic to neutral pH (pH 3–7). In addition, more negative LNP zeta potentials (up to −64 mV) correlate with enhanced colloidal stability due to the electrostatic repulsion between oil droplets. Furthermore, LNP modification such as acetylation and polymer grafting can significantly enhance emulsion stability by balancing surface wettability (hydrophilicity/hydrophobicity) and interfacial activity. A meta-analysis and support vector regressor with Bayesian optimization and eXplainable artificial intelligence (AI) analysis confirmed high-energy emulsification (ultrasonication, high-shear mixing), pH, and packing parameter (LNP_size/LNP_conc ratio) as the main features that can influence the formulation of emulsions and lead to smaller droplets and larger lifetimes. Finally, we propose heuristics to tailor LNP-stabilized Pickering emulsions that require stability and functionality, including those used in agriculture and crop protection, food, nutraceuticals, stimuli-responsive and energy systems, as well as coatings.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103752"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applications and advances in characterizing pore-interface structures in coal using small angle scattering technology: A review","authors":"Yixin Zhao ,&nbsp;Chengxi Wang ,&nbsp;Xiaodong Guo ,&nbsp;Shuaipeng Zhu ,&nbsp;Yingfeng Sun","doi":"10.1016/j.cis.2025.103769","DOIUrl":"10.1016/j.cis.2025.103769","url":null,"abstract":"<div><div>The multiscale pore-fracture interface in coal forms the fundamental physical basis governing both coalbed methane (CBM) storage-transport behavior and CO₂ geological storage efficiency. This review systematically discusses the principle of small angle scattering (SAS) technology in the analysis of coal matrix pore interface, and focuses on the frontier application of coal-fluid interface in terms of geometry, physicochemical properties and dynamic evolution. Results indicate that SAS can nondestructively quantify the entire pore system, including closed pores. Moreover, the predominance of closed pores in quantity and distribution is strongly affected by coal type and tectonic stress. The unique advantages of in-situ SAS technology in real-time tracking of interface dynamics and complex response mechanisms (such as expansion/contraction, pore damage and structural rearrangement of coal matrix under external fields such as gas adsorption, stress loading and pyrolysis) are analyzed. Through the interface fractal, SAS provides key parameters for quantitative description of interface complexity and its internal correlation with coal chemical composition. The application of “contrast-matching small-angle neutron scattering” (CM-SANS) in visualization of fluid accessibility, the key role of time-resolved small angle scattering technology in capturing instantaneous dynamic structural response of rock mass, and the cutting-edge technology of multi-scale and multi-dimensional data fusion are systematically discussed. The purpose of this review is to provide robust micromechanical support for understanding the coal-fluid interaction, thereby promoting innovation in energy and environmental engineering technologies such as CBM efficient development and carbon capture, utilization, and storage (CCUS).</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103769"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145866688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From non-porous to highly porous homogeneous and heterogeneous structures: The evolving role of deep eutectic solvents in customizing chitosan-based materials – A review","authors":"Roberto Castro-Muñoz ,&nbsp;Rene Cabezas","doi":"10.1016/j.cis.2025.103756","DOIUrl":"10.1016/j.cis.2025.103756","url":null,"abstract":"<div><div>To date, chitosan (CS) is the most investigated biopolymer due to its interesting physicochemical features and versatility in several applications. Due to its multiple chemical functionalities and adaptable ability toward several shapes, structures, materials and networks, CS is still explored by the research community and extends it to new applications. In this regard, deep eutectic solvents (DESs), a new generation of green solvents and additives, have recently been investigated in tuning the properties of CS derived materials and structures. In starting pioneering works, the use of DES was mainly focused on their complete blending with CS phases to generate fully miscible non-porous structured materials. However, the versatility of DES systems, depending on their nature, has turned into tailoring CS networks into highly porous structures with adjusted porosities according to the target application. The role of the DES in customizing CS structures has evolved from producing non-porous to the design of highly porous structures. Therefore, this review paper lays out the core successful applications of implementing distinct types of DESs into CS networks to improve specific properties (such as encapsulation capacity, drug delivery ability, mechanical and thermal stability, water absorption, porosity, tuned hydrophobicity, adhesive and self-healable properties, among others) in the resulting customized structures, including flat non-porous structures, eutectogels, aerogels, beads, monoliths, among other derivative structures. Apart from elucidating the modification protocols of CS networks assisted by DESs, we also pinpoint the key interactions between the polymer and the DES system, resulting in the desired structure. In addition, we also provide key findings on the role of DES in the chemical functionalization, quaternization, methylation and polymerization reaction of specific CS derivatives. After revising the current literature, we finally declare perspectives and future scopes of research in the field.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103756"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial reactions at gas–liquid and solid–liquid interfaces in underground hydrogen storage","authors":"Gloire Imani ,&nbsp;Lei Zhang ,&nbsp;Eike Marie Thaysen ,&nbsp;David A. Wood ,&nbsp;Aliakbar Hassanpouryouzband ,&nbsp;Dongyan Fan ,&nbsp;Shuaishi Fu ,&nbsp;Yongfei Yang ,&nbsp;Jun Yao ,&nbsp;Hai Sun","doi":"10.1016/j.cis.2025.103762","DOIUrl":"10.1016/j.cis.2025.103762","url":null,"abstract":"<div><div>Underground hydrogen storage (UHS) in porous formations is a promising technology for large-scale energy systems, but microbial activity poses potential risks to hydrogen purity, injectivity and recovery. This review examines the interfacial processes that govern microbial behavior in UHS, focusing on interactions at gas–liquid and solid–liquid interfaces where hydrogenotrophic metabolism, biofilm formation, and colloidal adhesion occur. Microbial colonization at rock-water interfaces alters key physicochemical properties, including wettability, interfacial tension, and capillarity, which in turn affect hydrogen retention and multiphase flow dynamics. We synthesize current knowledge on microbial attachment mechanisms to rock, mass transfer limitations for hydrogen consumption, and biofilm-induced pore modifications. Special emphasis is given to the impact of microbial activity on interfacial phenomena, such as bubble disconnection, wettability shifts, and surface fouling, which are relevant to hydrogen loss and system performance. This review aims to bridge that gap by providing an interdisciplinary synthesis of microbial interfacial dynamics relevant to UHS.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103762"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Machine learning for nanoparticle-based imaging: From rational design to precision diagnosis","authors":"Nan Kang ,&nbsp;Zengyue Li ,&nbsp;Fu Tan ,&nbsp;Zimei Liu ,&nbsp;Yao Yang ,&nbsp;Xiaoqing Qian ,&nbsp;Qian Zhang","doi":"10.1016/j.cis.2025.103773","DOIUrl":"10.1016/j.cis.2025.103773","url":null,"abstract":"<div><div>Nanoparticles have become essential in nanomedicine due to their tunable physicochemical properties and multifunctional capabilities, particularly in biomedical imaging for early disease detection and real-time therapeutic monitoring. Nevertheless, the rational design of nanoparticles with predictable behavior in complex biological environments remains significant challenges. Recent advances in machine learning have created novel paradigms for the precise design and efficient application of nanoparticle-based imaging platforms. This review summarizes recent progress in this area, covering machine learning-guided nanoparticle design and fabrication, elucidating their dynamic behavior in biological systems, optimizing cellular uptake and intracellular delivery, and improving imaging sensitivity alongside quantitative analytical precision through intelligent signal processing methodologies. Overall, the integration of machine learning has accelerated the development of intelligent nanoparticulate systems by establishing critical correlations between material parameters and biological performance, thereby driving innovation in precision imaging technologies.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103773"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145881623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The surface-first paradigm: Engineering nanocarriers for infection-responsive drug delivery","authors":"Rohan M. Shah ,&nbsp;Indu Pal Kaur ,&nbsp;Snehal R. Jadhav","doi":"10.1016/j.cis.2025.103761","DOIUrl":"10.1016/j.cis.2025.103761","url":null,"abstract":"<div><div>The surface of a nanocarrier is the frontline interface between its therapeutic cargo and the complex biological milieu it encounters. While traditional drug delivery research has focused on payload optimisation, emerging challenges, such as antimicrobial resistance, chronic inflammation, and site-specific pathology, demand a strategic pivot toward a surface-first paradigm. This review proposes a <em>surface-first</em> framework for nanocarrier engineering - prioritising dynamic, responsive, and selective surface interactions over conventional passive shielding. It critically evaluates the limitations of conventional surface modifications (e.g.<em>,</em> PEGylation) and spotlights zwitterionic coatings and platelet-cloaked nanoparticles as flagship examples of next-generation stealth and targeting. Using infection-responsive systems as exemplars, we show how surface chemistry not only improves pharmacokinetics and biodistribution but also serves as a precision trigger (e.g., pH-activated charge reversal and MMP-cleavable linkers) for on-demand activation at the site of need. We highlight the need for standardised surface-characterisation protocols, modular manufacturing schemes, and integrated diagnostic–therapeutic interfaces to support clinical translation. Embracing a surface-first approach is both timely and essential to drive the future of targeted therapy. While interfacial principles are well established, we focus on an infection-centred, mechanism-first synthesis that links core–surface co-design to controlled release.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"349 ","pages":"Article 103761"},"PeriodicalIF":19.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}