{"title":"Genetically modified organoids for tissue engineering and regenerative medicine","authors":"Qinmeng Zhang, Jin He, Danji Zhu, Yunxuan Chen, Mengdie Fu, Shifan Lu, Yuesheng Qiu, Guodong Zhou, Guoli Yang, Zhiwei Jiang","doi":"10.1016/j.cis.2024.103337","DOIUrl":"10.1016/j.cis.2024.103337","url":null,"abstract":"<div><div>To date, genetically modified organoids are emerging as a promising 3D modeling tool aimed at solving genetically relevant clinical and biomedical problems for regenerative medicine and tissue engineering. As an optimal vehicle for gene delivery, genetically modified organoids can enhance or reduce the expression of target genes through virus and non-virus-based gene transfection methods to achieve tissue regeneration. Animal experiments and preclinical studies have demonstrated the beneficial role of genetically modified organoids in various aspects of organ regeneration, including thymus, lacrimal glands, brain, lung, kidney, photoreceptors, <em>etc.</em> Furthermore, the technology offers a potential treatment option for various diseases, such as Fabry disease, non-alcoholic steatohepatitis, and Lynch syndrome. Nevertheless, the uncertain safety of genetic modification, the risk of organoid application, and bionics of current genetically modified organoids are still challenging. This review summarizes the researches on genetically modified organoids in recent years, and describes the transfection methods and functions of genetically modified organoids, then introduced their applications at length. Also, the limitations and future development directions of genetically modified organoids are included.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"335 ","pages":"Article 103337"},"PeriodicalIF":15.9,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuai Zhang , Shuye Zhang , Pengyu Zhu , Jiayi Li , Yifei Li , Chenglong Zhou , Qingyang Qiu , Xinyi Jing , Kyung-Wook Paik , Peng He
{"title":"Recent achievements and performance of nanomaterials in microwave absorption and electromagnetic shielding","authors":"Shuai Zhang , Shuye Zhang , Pengyu Zhu , Jiayi Li , Yifei Li , Chenglong Zhou , Qingyang Qiu , Xinyi Jing , Kyung-Wook Paik , Peng He","doi":"10.1016/j.cis.2024.103336","DOIUrl":"10.1016/j.cis.2024.103336","url":null,"abstract":"<div><div>Due to the swift advancement of the electronic industry and information technology, electromagnetic wave absorption materials are gaining significance in the field of intelligent equipment and weaponry. Nanomaterials were developed to investigate wave absorbing materials that can achieve both impedance matching and attenuation balance. Nanomaterials possess the properties of being thin, lightweight, and capable of absorbing microwave radiation across a wide range of frequencies. This work aims to present a systematic overview of the recent advancements in core-shell materials, specifically carbon, oxide, and sulfide nanomaterials, with regards to their applications in electromagnetic absorption and electromagnetic shielding. This review intends to emphasize the core principles of electromagnetic interference (EMI) shielding and microwave absorption in different systems documented in the literature, along with diverse methods of synthesis and fabrication for creating effective wideband electromagnetic absorbers/shields. Lastly, we also endeavor to offer a comprehensive view and insight into the areas where future research will thrive. This study provides a comprehensive assessment of the current advancements in the field of microwave absorption and electromagnetic shielding of nanomaterials.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"335 ","pages":"Article 103336"},"PeriodicalIF":15.9,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Viscoelastic properties of colloidal systems with attractive solid particles at low concentration: A review, new results and interpretations","authors":"Philippe Martinoty , Antoni Sánchez-Ferrer","doi":"10.1016/j.cis.2024.103335","DOIUrl":"10.1016/j.cis.2024.103335","url":null,"abstract":"<div><div>This paper concerns the viscoelastic properties and the resulting structure of colloidal systems with short-range attractions in the regime where the volume fraction f is small. Unlike the high ϕ regime, which is well understood in terms of mode-coupling theory (MCT), the low ϕ regime is still the subject of a debate based on different concepts such as percolation, diffusion-limited colloidal aggregation (DLCA), jamming, or cluster mode-coupling approach. Prior to the analysis of three examples of attractive systems at low ϕ values, a summary of concepts relevant to understanding the formation and properties of such attractive particles is discussed in the present study. Afterwards, we re-analyze the behaviour at a low ϕ of i) suspensions of carbon black (CB) particles, ii) suspensions of poly(methyl methacrylate) (PMMA) hard spheres with a depletion attraction induced by the addition of polystyrene (PS), and iii) suspensions of amino acid organogelator molecules which form rod-like objects. The rheological properties of these systems have been studied in detail and their response has been interpreted as being due either to a solid network discussed in relation to the jamming state diagram or to a suspension formed by jamming of clusters. Our analysis shows that these three systems are in fact cluster fluids and that their solid-like response corresponds to a change in their viscoelastic response, the elastic component G' becoming greater than the viscous component G\" at low frequencies. Due to the presence of weak interparticle interactions in the tens range from 1 to 15 k<sub>B</sub>T, a liquid-like state is reversibly achieved at high frequencies, as indicated by the crossover of G' and G\" as a function of frequency for a given concentration. Moreover, all these attractive particle systems at low ϕ show for both moduli a master curve which characterizes these cluster fluids and allows for the classification of these attractive particle systems.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"335 ","pages":"Article 103335"},"PeriodicalIF":15.9,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guangyi Kan , Lijia Chen , Wenjie Zhang , Qiqi Bian , Xichang Wang , Jian Zhong
{"title":"Recent advances in the development and application of curcumin-loaded micro/nanocarriers in food research","authors":"Guangyi Kan , Lijia Chen , Wenjie Zhang , Qiqi Bian , Xichang Wang , Jian Zhong","doi":"10.1016/j.cis.2024.103333","DOIUrl":"10.1016/j.cis.2024.103333","url":null,"abstract":"<div><div>The application of curcumin in food science is challenged by its poor water solubility, easy degradation under processing and within the gastrointestinal tract, and poor bioavailability. Micro/nanocarrier is an emerging and efficient platform to overcome these drawbacks. This review focuses on the recent advances in the development and application of curcumin-loaded micro/nanocarriers in food research. The recent development advances of curcumin-loaded micro/nanocarriers could be classified into ten basic systems: emulsions, micelles, dendrimers, hydrogel polymeric particles, polymer nanofibers, polymer inclusion complexes, liposomes, solid lipid particles, structured lipid carriers, and extracellular vesicles. The application advances of curcumin-loaded micro/nanocarriers for food research could be classified into four types: coloring agents, functional active agents, preservation agents, and quality sensors. This review demonstrated that micro/nanocarriers were excellent carriers for the fat-soluble curcumin and the obtained curcumin-loaded micro/nanocarriers had promising application prospects in the field of food science.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"335 ","pages":"Article 103333"},"PeriodicalIF":15.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biohybrid nano-platforms manifesting effective cancer therapy: Fabrication, characterization, challenges and clinical perspective","authors":"Mayur Aalhate , Srushti Mahajan , Anish Dhuri, Pankaj Kumar Singh","doi":"10.1016/j.cis.2024.103331","DOIUrl":"10.1016/j.cis.2024.103331","url":null,"abstract":"<div><div>Nanotechnology-based delivery systems have brought a paradigm shift in the management of cancer. However, the main obstacles to nanocarrier-based delivery are their limited circulation duration, excessive immune clearance, inefficiency in interacting effectively in a biological context and overcoming biological barriers. This demands effective engineering of nanocarriers to achieve maximum efficacy. Nanocarriers can be maneuvered with biological components to acquire biological identity for further regulating their biodistribution and cell-to-cell cross-talk. Thus, the integration of synthetic and biological components to deliver therapeutic cargo is called a biohybrid delivery system. These delivery systems possess the advantage of synthetic nanocarriers, such as high drug loading, engineerable surface, reproducibility, adequate communication and immune evasion ability of biological constituents. The biohybrid delivery vectors offer an excellent opportunity to harness the synergistic properties of the best entities of the two worlds for improved therapeutic outputs. The major spotlights of this review are different biological components, synthetic counterparts of biohybrid nanocarriers, recent advances in hybridization techniques, and the design of biohybrid delivery systems for cancer therapy. Moreover, this review provides an overview of biohybrid systems with therapeutic and diagnostic applications. In a nutshell, this article summarizes the advantages and limitations of various biohybrid nano-platforms, their clinical potential and future directions for successful translation in cancer management.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"335 ","pages":"Article 103331"},"PeriodicalIF":15.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wensi Jiang , Farzad Seidi , Yuqian Liu , Chengcheng Li , Yang Huang , Huining Xiao
{"title":"Cellulose-based functional textiles through surface nano-engineering with MXene and MXene-based composites","authors":"Wensi Jiang , Farzad Seidi , Yuqian Liu , Chengcheng Li , Yang Huang , Huining Xiao","doi":"10.1016/j.cis.2024.103332","DOIUrl":"10.1016/j.cis.2024.103332","url":null,"abstract":"<div><div>The emergence of smart textiles with the ability to regulate body temperature, monitor human motion, exhibit antibacterial properties, sound fire alarms, and offer fire resistance has sparked considerable interest in recently. MXene displays remarkable attributes like high metallic conductivity, electromagnetic shielding capability, and photothermal/electrothermal properties. Furthermore, due to the highly polar surface groups, MXene nanosheets show exceptional hydrophilic properties and are able to establish strong connections with the polar surfaces of natural fabrics. This review focuses on the most recent developments in altering the surface of cellulosic textiles with MXene and MXene-based composites. The combination of MXene with other modifier agents, such as phosphorous compounds, graphene, carbon nanotube, conductive polymers, antibacterial macromolecules, superhydrophobic polymers, and metal or metal oxide nanoparticles, imparts diverse functionalities to textiles, such as self-cleaning and fire resistance. Moreover, the synergistic effects between these modifier agents with MXenes can improve MXene-related properties like antibacterial, photothermal, electrothermal, and motion- and fire-sensing characteristics.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"335 ","pages":"Article 103332"},"PeriodicalIF":15.9,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent progress and current status of surface engineered magnetic nanostructures in cancer theranostics","authors":"Bijaideep Dutta , K.C. Barick , P.A. Hassan , A.K. Tyagi","doi":"10.1016/j.cis.2024.103320","DOIUrl":"10.1016/j.cis.2024.103320","url":null,"abstract":"<div><div>Cancer theranostic is the combination of diagnosis and therapeutic modalities for cancer treatment. It realizes a more flexible, precise and non-invasive treatment of patients. In this aspect, magnetic nanostructures (MNSs) have gained paramount importance and revolutionized the cancer management due to their unique physicochemical properties and inherent magnetic characteristics. MNSs have amazing theranostic ability starting from drug delivery to magnetic hyperthermia and magnetic resonance imaging to multimodal imaging in association with radioisotopes or fluorescent probes. Precise regulation over the synthetic process and their consequent surface functionalization makes them even more fascinating. The ultimate goal is to develop a platform that combines multiple diagnostic and therapeutic functionalities based on MNSs. This perspective has provided an overview of the state-of-art of theranostic applications of MNSs. Special emphasis has been dedicated towards the importance of synthetic approaches of MNSs as well as their subsequent surface engineering and integration with biological/therapeutic molecules that decide the final outcomes of the efficacy of MNSs in theranostic applications. Moreover, the recent advancements, opportunities and allied challenges towards clinical applications of MNSs in cancer management have been demonstrated.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"334 ","pages":"Article 103320"},"PeriodicalIF":15.9,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin Xu , Pan Xue , Meng Gao , Yibin Li , Zijun Xu , Yu Wei , Zhengjian Zhang , Yang Liu , Lei Wang , Hongbin Liu , Bowen Cheng
{"title":"Assembled one-dimensional nanowires for flexible electronic devices via printing and coating: Techniques, applications, and perspectives","authors":"Xin Xu , Pan Xue , Meng Gao , Yibin Li , Zijun Xu , Yu Wei , Zhengjian Zhang , Yang Liu , Lei Wang , Hongbin Liu , Bowen Cheng","doi":"10.1016/j.cis.2023.102987","DOIUrl":"10.1016/j.cis.2023.102987","url":null,"abstract":"<div><p><span><span><span>The rapid progress in flexible electronic devices has necessitated continual research into nanomaterials, structural design, and fabrication processes. One-dimensional </span>nanowires, characterized by their distinct structures and exceptional properties, are considered essential components for various flexible electronic devices. Considerable attention has been directed toward the assembly of nanowires, which presents significant advantages. Printing and </span>coating techniques can be used to assemble nanowires in a relatively simple, efficient, and cost-competitive manner and exhibit potential for scale-up production in the foreseeable future. This review aims to provide an overview of nanowire assembly using printing and coating techniques, such as bar coating, </span>spray<span> coating, dip coating, blade coating, 3D printing, and so forth. The application of assembled nanowires in flexible electronic devices is subsequently discussed. Finally, further discussion is presented on the potential and challenges of flexible electronic devices based on assembled nanowires via printing and coating.</span></p></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"321 ","pages":"Article 102987"},"PeriodicalIF":15.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Monolayers of amino acid-type amphiphiles","authors":"D. Vollhardt , G. Brezesinski , R. Rudert","doi":"10.1016/j.cis.2023.103001","DOIUrl":"10.1016/j.cis.2023.103001","url":null,"abstract":"<div><p><span>The monolayer characteristics of selected N-alkanoyl substituted α-amino acid are studied with the objective to demonstrate the specific effect of the chemical structure of the polar head group which is highlighted with the D- and L-enantiomers of the following selected examples: R-alanine, R-serine, R-threonine, R-allo-threonine, and R-aspartic acid (R = C</span><sub>16</sub>, C<sub>18</sub><span>). The thermodynamic effect of the head group variation is studied. Experimental π-A isotherms of the N-tetradecyl-L-alanine monolayers show similar behavior as those of usual amphiphiles. The -CH</span><sub>3</sub>-group in R-alanine with the simplest head group structure is substituted by a -CH<sub>2</sub><span>-OH group in R-serine and serine methylester and by a -CH- CH</span><sub>3</sub><span><span>-OH group in R-threonine (or allo-threonine) and threonine methylester. The introduction of the </span>methyl group<span> in 3-position of serine (serine to 3-methyl-serine = threonine) shifts the characteristic temperatures by >20 K to lower values determined for N-C16-D</span></span><span>l</span>-serine. The formation of the corresponding methylester decreases these temperatures by 15 K for serine with the shorter (C16) alkyl chain and only by ∼5 K for threonine with the longer chain (C18). The π–A curves of the enantiomeric and racemic allo-forms show similar features to those of N-stearoyl-threonine. The absolute T<sub>0</sub>-values (disappearance of the LE/LC-transition) are 4–5 K larger compared with the corresponding N-stearoyl-threonines, but the ΔT<sub>0</sub> between the enantiomeric (D) and the racemic (DL) forms is only slightly larger than that of N-stearoyl-threonine.</p><p><span>Monolayers of different N-alkanoyl substituted α-amino acid amphiphiles have been mesoscopically characterized. Substantial topological differences are observable at the condensed phase domains of several amino acid amphiphiles, such as, N-palmitoyl </span>aspartic acid<span><span>, N-palmitoyl- or N-stearoyl serine methyl ester, N-stearoyltyrosine, N-palmitoyl or N-myristoyl </span>alanine. Many fascinating domain shapes are found, but always the curvatures of the two enantiomeric forms are directed in an opposite sense. The domain shape of the 1:1 racemic mixtures is usually different, but very often oppositely curved texture elements are observable.</span></p><p><span>GIXD is used to study the characteristic features of the lattice structure of condensed monolayer phases on the Angstrom scale. Specific for all structures is the large tilt angle with respect to the surface normal, which decreases only marginally by compression. The large size of the head groups and strong interactions between them dominate the monolayer structure. As presented for N</span><img>C16<img> and N-C18-threonine, N-C16-DL -serine, N-C16-L -serine, N<img>C16<img> DL -serine-ME, N<img>C16<img> L -serine-ME, N<img>C18<img> DL -threonine-ME, and N<img>C18<img><span><span>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"321 ","pages":"Article 103001"},"PeriodicalIF":15.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suliman Khan , Mojtaba Falahati , William C. Cho , Yasaman Vahdani , Rabeea Siddique , Majid Sharifi , Laila Abdulmohsen Jaragh-Alhadad , Setareh Haghighat , Xiaoju Zhang , Timo L.M. ten Hagen , Qian Bai
{"title":"Core–shell inorganic NP@MOF nanostructures for targeted drug delivery and multimodal imaging-guided combination tumor treatment","authors":"Suliman Khan , Mojtaba Falahati , William C. Cho , Yasaman Vahdani , Rabeea Siddique , Majid Sharifi , Laila Abdulmohsen Jaragh-Alhadad , Setareh Haghighat , Xiaoju Zhang , Timo L.M. ten Hagen , Qian Bai","doi":"10.1016/j.cis.2023.103007","DOIUrl":"10.1016/j.cis.2023.103007","url":null,"abstract":"<div><p>It is well known that metal–organic framework (MOF) nanostructures have unique characteristics such as high porosity, large surface areas and adjustable functionalities, so they are ideal candidates for developing drug delivery systems (DDSs) as well as theranostic platforms in cancer treatment. Despite the large number of MOF nanostructures that have been discovered, conventional MOF-derived nanosystems only have a single biofunctional MOF source with poor colloidal stability. Accordingly, developing core–shell MOF nanostructures with good colloidal stability is a useful method for generating efficient drug delivery, multimodal imaging and synergistic therapeutic systems. The preparation of core–shell MOF nanostructures has been done with a variety of materials, but inorganic nanoparticles (NPs) are highly effective for drug delivery and imaging-guided tumor treatment. Herein, we aimed to overview the synthesis of core–shell inorganic NP@MOF nanostructures followed by the application of core–shell MOFs derived from magnetic, quantum dots (QDs), gold (Au), and gadolinium (Gd) NPs in drug delivery and imaging-guided tumor treatment. Afterward, we surveyed different factors affecting prolonged drug delivery and cancer therapy, cellular uptake, biocompatibility, biodegradability, and enhanced permeation and retention (EPR) effect of core–shell MOFs. Last but not least, we discussed the challenges and the prospects of the field. We envision this article may hold great promise in providing valuable insights regarding the application of hybrid nanostructures as promising and potential candidates for multimodal imaging-guided combination cancer therapy.</p></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"321 ","pages":"Article 103007"},"PeriodicalIF":15.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0001868623001744/pdfft?md5=f62f4039dedbe2ce49e65629fbee4499&pid=1-s2.0-S0001868623001744-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41184476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}