Advances in Colloid and Interface Science最新文献

{"title":"Toward green and sustainable dielectric nanofluids: surfactant impacts on stability, properties, and regulations","authors":"Rizwan A. Farade ,&nbsp;Noor Izzi Abdul Wahab ,&nbsp;Zafar Said ,&nbsp;T.M. Yunus Khan ,&nbsp;C. Ahamed Saleel","doi":"10.1016/j.cis.2025.103668","DOIUrl":"10.1016/j.cis.2025.103668","url":null,"abstract":"<div><div>Transformer fluids face major limitations in the dielectric strength and thermal conductivity of fluids, which hinders effective application in high-voltage applications. Adding nanoparticles holds potential for enhancement, but it is challenging to accomplish and maintain a stable dispersion because of a tendency toward agglomeration. Surfactants are found to act as critical stabilizing agents that aid in the dispersion of nanoparticles and temporal stability through steric and electrostatic interactions at the oil-nanoparticle interface. This review closely evaluates the preparation methodologies of dielectric nanofluids, paying specific attention to the functionality of surfactants and temporal stability effects. Surfactant-treated nanofluids showed temporal stability from a few weeks to a few months along with significant enhancements: breakdown voltage (up to 93.17%), dielectric constant (up to 47.4%), decrease in dissipation factor (up to 97.3%), increase in resistivity (up to 917.93%), and enhancement in thermal conductivity (up to 216.2%). These enhancements are necessarily connected to interfacial alterations that control charge trapping, polarization, and phonon conduction. Gaps between theoretical models of dielectric constant (like Maxwell-Garnett and Loyang models and others) and experimental findings are resolved to recommend enhancement considering surfactant-induced interfacial effects. Also, sustainability aspects such as biodegradability, toxicity, recyclability, and regulatory compliance are discussed. This review's uniqueness lies in a detailed discussion of interfacial mechanisms, model enhancements, and eco-friendly surfactant design, and suggestions for entering into molecular dynamics and interfacial modelling to rationally design environmentally sustainable, high-performance dielectric nanofluids.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103668"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biopolymer-based membranes and their application in per- and polyfluorinated substances removal: Perspective review","authors":"Roham Ghanbari ,&nbsp;Ratish Permala ,&nbsp;Stefan Iglauer ,&nbsp;Masoumeh Zargar","doi":"10.1016/j.cis.2025.103669","DOIUrl":"10.1016/j.cis.2025.103669","url":null,"abstract":"<div><div>Over the past 2 decades, <em>per</em>- and polyfluoroalkyl substances (PFAS) have attracted considerable attention due to their widespread occurrence and adverse effects on both the environment and human health. PFAS possess strong carbon‑fluorine bonds that confer exceptional chemical stability and resistance to natural degradation; their fluorinated chains are highly hydrophobic and oleophobic, while their polar functional groups contribute to amphiphilic behavior and water solubility. Certain PFAS thus pose serious risks to living organisms, especially mammals. Membrane filtration is recognized as a particularly effective technique, achieving removal efficiencies greater than 99 % for long-chain-PFAS (including anionic, cationic, and zwitterionic PFAS molecules). However, many conventional membrane processes rely on petroleum-based polymers and non-biodegradable materials which lead to significant sustainability concerns. The disposal of these materials harms the environment and contributes to secondary pollution. In this review, biopolymers are presented as alternatives and their different sources are categorized and discussed in detail. Further, the latest applications of commercial membranes for PFAS removal are discussed and compared with those of biopolymer-based membranes (BBMs). Finally, recommendations for advancing PFAS removal using BBMs are provided, and current knowledge gaps are highlighted. This manuscript therefore underscores the importance of evolving membrane technology within a circular economy framework.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103669"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isothermal microcalorimetry for scaffold design and characterization: Assessing bacterial and host cell interactions and physicochemical stability","authors":"Carmen Alvarez-Lorenzo,&nbsp;Angel Concheiro","doi":"10.1016/j.cis.2025.103681","DOIUrl":"10.1016/j.cis.2025.103681","url":null,"abstract":"<div><div>Scaffolds used in regenerative medicine are increasingly expected to address personalization, bioactivity, and sustainability, underscoring the need for characterization methods that reliably predict safety and efficacy. Isothermal microcalorimetry (IMC) offers a highly sensitive, label-free, real-time measurement of heat flow from energy-generating or -consuming process at scaffold interfaces. By monitoring microbial activity, host cell metabolism, material stability, and responses to environmental or therapeutic factors, IMC provides physiologically relevant insight into scaffold performance over extended periods. Its non-destructive, low-preparation, and passive nature preserves samples for complementary analyses, making it a versatile yet underutilized tool in biomedical research. This review introduces IMC for scaffold design and characterization, emphasizing its capacity to evaluate vulnerability to biofilm formation and the effectiveness of anti-biofilm strategies. It further explores applications in tracking scaffold formation, assessing host cell-material interactions and tissue development, and probing the antitumor potential of engineered scaffolds. The review concludes with a perspective on IMC's role in advancing scaffold translation within the evolving regulatory landscape shaped by the FDA Modernization Acts 2.0 and 3.0.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103681"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145217110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacteriogenic metallic and semiconducting nano-system as a potential sustainable solution for one health complexities","authors":"Vishal Chaudhary ,&nbsp;Sonu Sonu ,&nbsp;Pankaj Raizada ,&nbsp;Ajeet Kaushik","doi":"10.1016/j.cis.2025.103648","DOIUrl":"10.1016/j.cis.2025.103648","url":null,"abstract":"<div><div>Considering the complexities of electronics waste management to meet the requirements of digital-age technologies, this article underscores the pressing need for eco-friendly, economical, and sustainable engineering solutions. Here, it uniquely focuses on bacteriogenic metallic and semiconducting nano-systems as a promising yet underexplored solution for sustainable materials innovation. Unlike conventional green nanofabrication methods involving plants or eukaryotic microbes, bacteria possess numerous merits for fabrication, including ease of cultivation, a wide spectrum of genera, abundance, prompt cell division efficacy, genetic elasticity, and high bio-reduction/oxidation efficacy that make them highly adaptable platforms for engineered nanostructures. This article provides a comprehensive and first-of-its-kind framework integrating bacterial synthesis pathways (intercellular and extracellular), bacterial class (Monoderm and Diderm), reaction parameters (pH, temperature, precursor concentration), and molecular precursors (proteins, enzymes, exopolysaccharides, redox mediators). It further highlights emerging applications of bacteriogenic nanomaterials across medicine, energy, environment, and food sectors, enabled by their antipathogenic, catalytic, anticancer, antioxidant, photocatalytic, and biocompatible properties, contributing to the betterment of One Health. Besides, this article emphasizes exploring challenges like cytotoxicity, scalability, and stability, which restrict their transformative aspects. To address these obstacles, systematic studies including in-vitro/in-vivo toxicity, lifecycle, biodistribution and bioaccumulation analyses, and predictive modelling by adopting contemporary technologies like artificial intelligence (AI), complex systems, bioinformatics, and biotechnology to bridge the laboratory-to-market gap are suggested to enrich the suggested class of nano-systems. Overall, this article not only consolidates the state-of-the-art but also presents a novel interdisciplinary vision where bacterial complexity drives next-generation nanoengineering, aligning with the United Nations' sustainability goals.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103648"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144997403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accelerating the discovery and optimization of metal-organic framework materials via machine learning","authors":"Hong Wang ,&nbsp;Liang Yang ,&nbsp;Deying Leng ,&nbsp;Yurun Du ,&nbsp;Hao Ning","doi":"10.1016/j.cis.2025.103671","DOIUrl":"10.1016/j.cis.2025.103671","url":null,"abstract":"<div><div>As a novel class of porous materials, metal-organic frameworks (MOFs) have attracted considerable attention due to their extensive applications in gas storage, separation, catalysis, and other fields. Traditional methods for the synthesis and optimization of MOFs are often hindered by time-consuming processes and high costs. With the rapid advancement of machine learning (ML) technology, innovative solutions have been provided to accelerate the design, screening, and performance prediction of MOFs. This paper systematically reviews the progress of ML applications in MOF research, covering multiple aspects from fundamental theories to practical implementations. It first introduces commonly used ML algorithms, including regression analysis, classification algorithms, clustering analysis, deep learning, and reinforcement learning, and discusses methods for data acquisition and preprocessing, as well as their impact on model performance. It also examines model evaluation metrics and strategies for enhancing model interpretability. Subsequently, the paper focuses on how ML can drive the progress of MOF research through material design, high-throughput screening, structure-property relationship analysis, and performance prediction. Finally, it systematically identifies the current challenges and future development directions, emphasizing the importance of interdisciplinary collaboration. The significant value of this review lies in integrating the latest ML technologies with advancements in MOF research, providing researchers with a comprehensive perspective to understand the role of ML in accelerating the development of new materials. Additionally, this paper is of great significance in promoting communication between academia and industry, guiding experimental scientists to more effectively utilize computational tools for MOF-related research, thereby accelerating the development of new materials, advancing green chemistry and technology, and meeting the growing demands for energy and environmental sustainability.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103671"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145061110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart Pickering emulsions stabilized by functionalized nanoparticles: Innovative applications in advanced food packaging","authors":"Yi'er Lou ,&nbsp;Yuanxin Ouyang ,&nbsp;Hangyu Xie ,&nbsp;Honghong Tian ,&nbsp;Siting Li ,&nbsp;Min Wu ,&nbsp;Xueping Song","doi":"10.1016/j.cis.2025.103673","DOIUrl":"10.1016/j.cis.2025.103673","url":null,"abstract":"<div><div>Pickering emulsions (PEs) are dispersions stabilized by solid particles, have excellent stability and the ability to efficiently encapsulate and protect active ingredients sensitive to environment. Solid particles play a critical role in ensuring the stability and functionality of emulsions. Smart PEs with stimuli-responsive can respond to external stimuli such as pH, CO₂, temperature, light and magnetism to regulate the stability of the emulsion (emulsification or demulsification) and smartly control the release of the encapsulated active ingredient, making them highly valued across multiple industries, exceptionally in the preparation of advanced packaging materials. But conventional solid particles cannot endow the ability with stimuli-response to PEs. As a result, surface functionalization emerges as an essential approach for introducing stimuli responsiveness for nanoparticles as stabilizers of Smart PEs. This review introduces the stabilization mechanism and influencing factors of PEs, summarizes the stimuli-responsive mechanisms of nanoparticles for smart PEs and focus on functionalization employed to introduce stimuli responsiveness for nanoparticles. There has been a significant advance in surface modification of nanoparticles, employing the approaches of chemical grafting, electrostatic adsorption, self-assembly, co-precipitation and encapsulation. Meanwhile, the applications of smart PEs in active packaging, indicator packaging, self-healing packaging, and degradable packaging are presented. The current challenges and future directions of smart PEs applying to advanced packaging materials are also outlined. These insights will be invaluable for optimizing functions of smart PEs and broadening their application potential across various fields.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103673"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145088245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cationic antibacterial polymers for development of bactericidal materials: Strategies, mechanisms, and applications","authors":"Zhaochuan Yu ,&nbsp;Chao Deng ,&nbsp;Tong Lei ,&nbsp;Huijie Wang ,&nbsp;Yuqian Liu ,&nbsp;Chao Liu ,&nbsp;Farzad Seidi ,&nbsp;Qiang Yong ,&nbsp;Huining Xiao","doi":"10.1016/j.cis.2025.103658","DOIUrl":"10.1016/j.cis.2025.103658","url":null,"abstract":"<div><div>The worldwide consumption of antibiotics has significantly contributed to the escalating challenge of antibiotic resistance over the past decades. Therefore, there is a tremendous interest in the development of new non-antibiotic antibacterial agents as alternatives to traditional antimicrobial drugs, which could exhibit prolonged action, enhanced efficacy, and reduced toxicity. Among various antibacterial agents, cationic antibacterial polymers (CAPs) have been particularly appearing due to their plenty of positive-charged groups or segments, enabling them to interact effectively with the negatively charged surfaces of microorganisms, thereby inhibiting their growth. This review paper begins by summarizing the different types and features of CAPs including quaternary ammonium salt (QAS) polymers, guanidine salt (GS) polymers, and quaternary phosphonium salt (QPS) polymers, originating from both natural and synthetic polymers. Subsequently, the antimicrobial mechanisms of CAPs are further discussed, including electrostatic interactions, cell membrane damage, protein precipitation, and DNA damage, and it was pointed out that the synergistic effect of these mechanisms confers strong antimicrobial capabilities to CAPs. Additionally, the article extensively discusses the applications of CAPs in key areas such as textiles, medical care, food packaging, and water treatment, and identifies current challenges, such as the development of resistance, environmental impact, and potential biotoxicity. Moreover, this review summarizes the latest literature on the antibacterial activity of various CAPs combined with different polymers as substrates and provides future directions for exploring the novel non-antibiotic antibacterial agents for various applications.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103658"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145046490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A guide to soft colloidal lithography: Advances in microgels at fluid interfaces, preparation methods and applications of 2D microgel monolayers","authors":"Antonio Rubio-Andrés,&nbsp;Delfi Bastos-González,&nbsp;Miguel Angel Fernandez-Rodriguez","doi":"10.1016/j.cis.2025.103684","DOIUrl":"10.1016/j.cis.2025.103684","url":null,"abstract":"<div><div>Nanostructured surfaces have gained significant attention over recent decades due to their diverse technological applications across multiple fields. The fabrication of artificial nanostructures typically relies on lithographic approaches, yet conventional lithography techniques face challenges related to scalability and high costs, prompting the emergence of soft colloidal lithography (SCL) as a promising alternative for designing large-scale crystalline nanostructures. SCL exploits the rapid and large scale self-assembly of microgels at fluid interfaces and their subsequent transfer to solid substrates. Despite its potential, SCL remains underused in most clean room facilities, hindering its implementation in industrial processes. This review addresses this gap by providing both soft matter and materials science communities with tools to effectively design SCL-based materials. We start presenting an updated overview of microgel behavior at fluid interfaces, which is the platform providing the better tools to tune the final monolayer pattern. We then present a comprehensive guidance on preparation procedures, encompassing both direct assembly methods and interface-assisted approaches. Finally, we review applications of SCL-fabricated materials, including those where deposited microgels serve as functional elements and those where monolayers function as either positive masks for nanowire fabrication or negative masks for nanohole production. Throughout the review, we identify promising research directions to advance the SCL technique and propose applications where this methodology could enhance existing technologies.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103684"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145314354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fusogenic lipid nanocarriers: Nature-inspired design for advanced drug delivery systems","authors":"Gennaro Balenzano ,&nbsp;Numan Eczacioglu ,&nbsp;Nunzio Denora ,&nbsp;Andreas Bernkop-Schnürch","doi":"10.1016/j.cis.2025.103667","DOIUrl":"10.1016/j.cis.2025.103667","url":null,"abstract":"<div><div>Lipid nanocarriers are a useful tool for intracellular delivery of drugs that are otherwise unable to enter their target cells. Most of these nanocarriers are designed for an endocytotic uptake, although this route of intracellular drug delivery has a number of shortcomings. A promising alternative is fusogenic lipid nanocarriers, since by this uptake mechanism lysosomal degradation problems being associated with endocytosis can be excluded and drug release into the target cell can be synchronized with the fusion process. Various mechanisms being responsible for biological fusion events, including fertilization, exocytosis, viral infection and plasma membrane repair can be copied and transferred to nanocarriers enabling them to fuse with target cells. In particular, curvature, fluidity and surface charge of nanocarriers are key parameters for fusogenic properties. Furthermore, lipid nanocarriers can be decorated with fusogenic (poly)peptides such as viral fusion peptides or SNARE-derived lipopeptides. Within this review we provide an overview about the underlying mechanisms being responsible for cell membrane fusion processes, we demonstrate how this knowledge can be utilized for the design of fusogenic lipid nanocarriers and we summarize most promising applications of fusogenic nanocarriers for treatment of different diseases.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103667"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cyclodextrins-amphiphile molecules supramolecular self-assemblies: Mechanisms, characterization, and applications in advanced functional materials","authors":"Xingran Kou ,&nbsp;Nan Gao ,&nbsp;Jiamin Zhu ,&nbsp;Hui Wang ,&nbsp;Xin Huang ,&nbsp;Yunchong Zhang ,&nbsp;Feng Chen ,&nbsp;Qinfei Ke ,&nbsp;Qingran Meng","doi":"10.1016/j.cis.2025.103676","DOIUrl":"10.1016/j.cis.2025.103676","url":null,"abstract":"<div><div>Cyclodextrins and their derivatives (CDs) have become ideal host for constructing various self-assemblies due to their unique external hydrophilic and internal hydrophobic cavities. The primary supramolecular inclusion complexes (ICs) fabricated by CDs and amphiphilic molecules are able to further self-assemble into different high-order supramolecular self-assemblies with more complex structure and more diverse functions under various non-covalent interactions. Hence, in-depth understanding of the assembly mechanisms &amp; modulating factors of amphiphilic molecules-CDs ICs and supramolecular self-assemblies (aggregates) as well as multiscale characterization methodologies is crucial for the design, construction, and application of novel CDs-based functional materials. Therefore, this paper systematically reviewed the latest research progress in supramolecular aggregates of CDs and amphiphilic molecules, and the influences of host, guest, and auxiliaries on the host-guest interaction and supramolecular aggregation were mainly discussed. Moreover, the relevant characterization methods of CDs-based supramolecular aggregates and their potential application prospect in different fields were also reviewed. Finally, the limitations and possible countermeasures of the current research on CDs-based supramolecular aggregates were briefly sorted out, in order to provide guidance for scientific research and practical applications in the field of CDs-based supramolecular self-assemblies.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"346 ","pages":"Article 103676"},"PeriodicalIF":19.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}