{"title":"Hydrogel adhesives for tissue recovery","authors":"Haohao Cui , Jingguo Li","doi":"10.1016/j.cis.2025.103496","DOIUrl":null,"url":null,"abstract":"<div><div>Hydrogel adhesives (HAs) are promising and rewarding tools for improving tissue therapy management. Such HAs had excellent properties and potential applications in biological tissues, such as suture replacement, long-term administration, and hemostatic sealing. In this review, the common designs and the latest progress of HAs based on various methodologies are systematically concluded. Thereafter, how to deal with interfacial water to form a robust wet adhesion and how to balance the adhesion and non-adhesion are underlined. This review also provides a brief description of gelation strategies and raw materials. Finally, the potentials of wound healing, hemostatic sealing, controlled drug delivery, and the current applications in dermal, dental, ocular, cardiac, stomach, and bone tissues are discussed. The comprehensive insight in this review will inspire more novel and practical HAs in the future.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103496"},"PeriodicalIF":15.9000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Colloid and Interface Science","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0001868625001071","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Hydrogel adhesives (HAs) are promising and rewarding tools for improving tissue therapy management. Such HAs had excellent properties and potential applications in biological tissues, such as suture replacement, long-term administration, and hemostatic sealing. In this review, the common designs and the latest progress of HAs based on various methodologies are systematically concluded. Thereafter, how to deal with interfacial water to form a robust wet adhesion and how to balance the adhesion and non-adhesion are underlined. This review also provides a brief description of gelation strategies and raw materials. Finally, the potentials of wound healing, hemostatic sealing, controlled drug delivery, and the current applications in dermal, dental, ocular, cardiac, stomach, and bone tissues are discussed. The comprehensive insight in this review will inspire more novel and practical HAs in the future.
期刊介绍:
"Advances in Colloid and Interface Science" is an international journal that focuses on experimental and theoretical developments in interfacial and colloidal phenomena. The journal covers a wide range of disciplines including biology, chemistry, physics, and technology.
The journal accepts review articles on any topic within the scope of colloid and interface science. These articles should provide an in-depth analysis of the subject matter, offering a critical review of the current state of the field. The author's informed opinion on the topic should also be included. The manuscript should compare and contrast ideas found in the reviewed literature and address the limitations of these ideas.
Typically, the articles published in this journal are written by recognized experts in the field.