Advances in Colloid and Interface Science最新文献_第2页

Comprehensive strategies for constructing efficient CRISPR/Cas based cancer therapy: Target gene selection, sgRNA optimization, delivery methods and evaluation

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-25 DOI: 10.1016/j.cis.2025.103497

Sathishbabu Paranthaman , Chinnappa A. Uthaiah , Shadab Md , Huda Mohammed Alkreathy

{"title":"Comprehensive strategies for constructing efficient CRISPR/Cas based cancer therapy: Target gene selection, sgRNA optimization, delivery methods and evaluation","authors":"Sathishbabu Paranthaman , Chinnappa A. Uthaiah , Shadab Md , Huda Mohammed Alkreathy","doi":"10.1016/j.cis.2025.103497","DOIUrl":"10.1016/j.cis.2025.103497","url":null,"abstract":"<div><div>Cancer is a complicated disease that results from the interplay between specific changes in cellular genetics and diverse microenvironments. The application of high-performance and customizable clustered regularly interspaced palindromic repeats/associated protein (CRISPR/Cas) nuclease systems has significantly enhanced genome editing for accurate cancer modeling and facilitated simultaneous genetic modification for cancer therapy and mutation identification. Achieving an effective CRISPR/Cas platform for cancer treatment depends on the identification, selection, and optimization of specific mutated genes in targeted cancer tissues. However, overcoming the off-target effects, specificity, and immunogenicity are additional challenges that must be addressed while developing a gene editing system for cancer therapy. From this perspective, we briefly covered the pipeline of CRISPR/Cas cancer therapy, identified target genes to optimize gRNAs and sgRNAs, and explored alternative delivery modalities, including viral, non-viral, and extracellular vesicles. In addition, the list of patents and current clinical trials related to this unique cancer therapy method is discussed. In summary, we have discussed comprehensive start-to-end pipeline strategies for CRISPR/Cas development to advance the precision, effectiveness, and safety of clinical applications for cancer therapy.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103497"},"PeriodicalIF":15.9,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomimetic materials for efficient emulsion separation: Based on the perspective of energy

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-24 DOI: 10.1016/j.cis.2025.103486

Hanpeng Gao , Haiyu Qian , Zong Meng , Siyu Chang , Xi Wang , Zhiwu Han , Yan Liu

{"title":"Biomimetic materials for efficient emulsion separation: Based on the perspective of energy","authors":"Hanpeng Gao , Haiyu Qian , Zong Meng , Siyu Chang , Xi Wang , Zhiwu Han , Yan Liu","doi":"10.1016/j.cis.2025.103486","DOIUrl":"10.1016/j.cis.2025.103486","url":null,"abstract":"<div><div>Purifying emulsified oily wastewater is particularly crucial for solving environmental pollution and water scarcity. Membrane separation shows great potential for emulsified wastewater treatment. However, realizing continued effective emulsion separation remains a significant challenge. Fortunately, various kinds of creative schemes have been proposed to overcome the current dilemma. In this paper, biomimetic emulsion separation materials with unique wettability are introduced. Besides, This article summarizes the recently advanced emulsion separation strategies. First, we analyze the typical wettability theory and explore the trade-off between separation flux and efficiency. After that, based on emulsion types, the current common emulsion separation materials are summarized and analyzed. Notably, the integration of natural biological inspiration has made separation materials full of potential. Further, from the perspective of external energy input or no-external energy input, this article provides an overview of advanced emulsion separation materials and analyzes the potential separation mechanism. Encouragingly, efficient emulsion separation can be realized by membrane characteristics (microstructure, superwettability, electrostatic interaction) or the appropriate external stimulus (photo, electricity, magnetic). Finally, the challenges and trends are summarized. We hope that this article will provide inspiration for the advancement of novel generations of separation materials.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103486"},"PeriodicalIF":15.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143734842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimating fluid-solid interfacial free energies for wettabilities: A review of molecular simulation methods

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-24 DOI: 10.1016/j.cis.2025.103482

Yafan Yang , Arun Kumar Narayanan Nair , Shuyu Sun , Denvid Lau

{"title":"Estimating fluid-solid interfacial free energies for wettabilities: A review of molecular simulation methods","authors":"Yafan Yang , Arun Kumar Narayanan Nair , Shuyu Sun , Denvid Lau","doi":"10.1016/j.cis.2025.103482","DOIUrl":"10.1016/j.cis.2025.103482","url":null,"abstract":"<div><div>Fluid-solid interfacial free energy (IFE) is a fundamental parameter influencing wetting behaviors, which play a crucial role across a broad range of industrial applications. Obtaining reliable data for fluid-solid IFE remains challenging with experimental and semi-empirical methods, and the applicability of first-principle theoretical methods is constrained by a lack of accessible computational tools. In recent years, a variety of molecular simulation methods have been developed for determining the fluid-solid IFE. This review provides a comprehensive summary and critical evaluation of these techniques. The developments, fundamental principles, and implementations of various simulation methods are presented from mechanical routes, such as the contact angle approach, the technique using Bakker's equation, and the Wilhelmy simulation method, as well as thermodynamic routes, including the cleaving wall method, the Frenkel-Ladd technique, and the test-volume/area methods. These approaches can be applied to compute various fluid-solid interfacial properties, including IFE, relative IFE, surface stress, and superficial tension, although these properties are often used without differentiation in the literature. Additionally, selected applications of these methods are reviewed to provide insight into the behavior of fluid-solid interfacial energies in diverse systems. We also illustrate two interpretations of the fluid-solid IFE based on the theory of Navascués and Berry and Bakker's equation. It is shown that the simulation methods developed from these two interpretations are identical. This review advocates for the broader adoption of molecular simulation methods in estimating fluid-solid IFE, which is essential for advancing our understanding of wetting behaviors in various chemical systems.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103482"},"PeriodicalIF":15.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Next-generation stimuli-responsive smart membranes: Developments in oil/water separation

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-24 DOI: 10.1016/j.cis.2025.103487

Aamal Rehman , Manzar Sohail , Nadeem Baig , Kai Yuan , Ahmed Abdala , Md A. Wahab

{"title":"Next-generation stimuli-responsive smart membranes: Developments in oil/water separation","authors":"Aamal Rehman , Manzar Sohail , Nadeem Baig , Kai Yuan , Ahmed Abdala , Md A. Wahab","doi":"10.1016/j.cis.2025.103487","DOIUrl":"10.1016/j.cis.2025.103487","url":null,"abstract":"<div><div>Effective treatment of oil-contaminated wastewater is essential due to its severe environmental and health impacts. The membrane-based separation is cost-effective, energy-efficient, and eco-friendly; however, fouling has remained a pressing issue. Stimuli-responsive membranes, which adjust their pore structure and surface properties in response to external triggers such as light, pH, and temperature, offer enhanced fouling resistance and improved separation performance. This review provides a comprehensive analysis of stimuli-responsive membranes for oil/water separation, emphasizing the role of smart polymeric materials engineered for controllable separation processes. We critically assess the strengths of these advanced membranes, including their tuneable wettability and energy-efficient operation, while identifying key limitations such as long-term stability, response time, scalability, and cost-effectiveness. Furthermore, the review explores various polymer types, synthesis methods, and fabrication techniques, evaluating their effectiveness in separation applications. Finally, the review concludes by outlining the challenges and proposing future directions to enhance the performance of stimuli-responsive membranes. By offering valuable insights into the dynamic control of membrane structures and properties, this study aims to inspire the development of next-generation stimuli-responsive membranes, drive their commercialization, and promote sustainable water treatment solutions.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103487"},"PeriodicalIF":15.9,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143740081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review on asphaltene precipitation and deposition kinetics and CO2 interactions

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-22 DOI: 10.1016/j.cis.2025.103488

Kwamena Ato Quainoo, Bai Baojun, Wei Mingzhen

{"title":"Review on asphaltene precipitation and deposition kinetics and CO2 interactions","authors":"Kwamena Ato Quainoo, Bai Baojun, Wei Mingzhen","doi":"10.1016/j.cis.2025.103488","DOIUrl":"10.1016/j.cis.2025.103488","url":null,"abstract":"<div><div>The precipitation and deposition of asphaltenes during enhanced oil recovery (EOR) and flow assurance operations, creates a huge problem that impacts operational efficiency during crude oil production. The changing of operating parameters such as composition of the oil system, including the impact of kinetics during production can lead to asphaltene related challenges such as reduced reservoir permeability, increased oil viscosity, and plugged pipelines. Understanding the complexities of asphaltene precipitation and deposition in the presence of CO<sub>2</sub> and the complex kinetic behavior is key to mitigating the related problems of asphaltenes. In this review, an effort was made to examine all relevant articles concerning asphaltene precipitation during CO<sub>2</sub> interactions with oil and their kinetics, aiming to enhance our understanding of asphaltene behavior in crude or model oil systems. Additionally, the review discusses current remediation strategies used to address asphaltene-related issues, including several field cases. The insights obtained highlight the critical role of kinetics in monitoring asphaltene behavior including predicting asphaltene formation within production systems that involves the use of CO<sub>2</sub> to boost oil recovery. Consequently, short-term evaluations and model systems are not representative enough for accurately predicting asphaltene precipitation although common in open literature. With the increase in CO<sub>2</sub> EOR, accurate prediction of asphaltene precipitation is crucial for designing carbon dioxide flooding plans. This review brings together various viewpoints, providing industry stakeholders with a detailed understanding of the challenges linked to asphaltenes, especially in the context of promoting CO2 utilization for EOR. This insight underscores the necessity for precise research to develop effective prevention and treatment methods.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103488"},"PeriodicalIF":15.9,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143696556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progress in heterostructures for photoelectrocatalytic reduction of carbon dioxide into fuels and value-added products 将二氧化碳光电催化还原为燃料和增值产品的异质结构研究进展

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-22 DOI: 10.1016/j.cis.2025.103483

Hubdar Ali Maitlo , Sherif A. Younis , Caroline Sunyong Lee , Ki-Hyun Kim

{"title":"Progress in heterostructures for photoelectrocatalytic reduction of carbon dioxide into fuels and value-added products","authors":"Hubdar Ali Maitlo , Sherif A. Younis , Caroline Sunyong Lee , Ki-Hyun Kim","doi":"10.1016/j.cis.2025.103483","DOIUrl":"10.1016/j.cis.2025.103483","url":null,"abstract":"<div><div>Carbon capture and utilization (CCU) technology offers a sustainable option to simultaneously address both energy crisis and environmental pollution such as catalytic reduction of carbon dioxide (CO<sub>2</sub>) into value-added fuel products (e.g., C<sub>1</sub>–C<sub>3</sub>). Among diverse CCU strategies, the light-irradiated photoelectrocatalytic (PEC) approach is recognized as a cutting-edge option for efficient CO<sub>2</sub> reduction reaction (RR) through the integration of photocatalysis and electrocatalysis within a one-stage hybridized catalytic system. Therefore, this review is meticulously structured to elucidate the potential utility of advanced composite catalysts (e.g., titanium dioxide, metal-organic frameworks, and organic/miscellaneous heterostructure materials) in PEC-CO<sub>2</sub>RR. It also examines the factors and processes governing their PEC-CO<sub>2</sub>RR activites in relation to their reduction pathways, electronic structures, charge-carrier dynamics, types of electrolytes, mass transfer, light-adsorption potential, and the viability of active sites. The fundamental principles and working mechanisms of diverse catalytic materials in PEC-CO<sub>2</sub>RR are also outlined to help establish the advanced catalytic systems based on performance assessments (e.g., in terms of CO<sub>2</sub> conversion rate, quantum yield, and space-time yield). Overall, this review is expected to deliver the new path for the construction of the next-generation PEC-CO<sub>2</sub>RR systems that are upscalable, stable, and reusable with enhanced catalytic activity.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103483"},"PeriodicalIF":15.9,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143696124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanocatalysts encapsulated in metal-organic frameworks: Size control and positive influences

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-22 DOI: 10.1016/j.cis.2025.103485

Lijun Liao, Ruting Yuan, Zhenzi Li, Wei Zhou

{"title":"Nanocatalysts encapsulated in metal-organic frameworks: Size control and positive influences","authors":"Lijun Liao, Ruting Yuan, Zhenzi Li, Wei Zhou","doi":"10.1016/j.cis.2025.103485","DOIUrl":"10.1016/j.cis.2025.103485","url":null,"abstract":"<div><div>Beyond traditional porous materials, metal-organic frameworks (MOFs) have attracted considerable attention for fabricating encapsulated nanocatalysts in the pores/cavities/channels of MOFs due to the high surface area, porous structure, and a large variety of organic linkers. As the host for nanocatalyst encapsulation, MOFs can provide uniform hierarchical pores and channels that can accelerate the mass transfer and migration of reactants or products and various metal‑oxygen clusters and organic linkers, which may interact strongly with nanocatalysts. Herein, state-of-the-art advancements in the encapsulation of nanocatalysts, including catalyst nanoparticles, clusters, quantum dots, and single-atom catalysts, have been summarized. The synthetic methods for nanocatalysts in MOFs and the enhanced properties are especially discussed. Then, positive effects upon the encapsulation of nanocatalysts in MOFs, including tunable chemical environment and encapsulation effects have been explored. Notably, the catalytic activity and product selectivity can be much improved by regulating the chemical environment around nanocatalysts and the interaction between the active nanocatalysts and metal nodes or organic linkers. Finally, challenges and future perspectives in encapsulated nanocatalysts in MOFs are proposed. This review could shed light on the construction of stable nanocatalysts encapsulation in MOFs with maximum exposed active sites and excellent activity in significant reactions.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103485"},"PeriodicalIF":15.9,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular insights: How counterions determine surfactant aggregation

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-22 DOI: 10.1016/j.cis.2025.103484

Lili Zhou , Zhang Liu , Yilin Wang

{"title":"Molecular insights: How counterions determine surfactant aggregation","authors":"Lili Zhou , Zhang Liu , Yilin Wang","doi":"10.1016/j.cis.2025.103484","DOIUrl":"10.1016/j.cis.2025.103484","url":null,"abstract":"<div><div>The morphology of surfactant aggregates inherently determines their properties and functions. Hence, the modulation of morphology holds significant importance in their applications. Opting for an appropriate counterion emerges as an efficient and convenient method to shape the aggregate morphology of ionic surfactants. Both inorganic and organic counterions exert influence on surfactant aggregation by neutralizing the repulsive headgroup charges and synergistically adjusting the hydrophobic association among the alkyl tails. In this process, the charge property, polarizability, hydrophobicity, configuration, and functional groups of counterions are of pivotal influencing factors. A delicate adjustment of counterion structures can yield dramatic differences in the aggregation behavior of ionic surfactants. This review provides a comprehensive overview of the fundamental principles governing the impact of inorganic and organic counterions on the formation of diverse surfactant aggregates, encompassing spherical micelles, wormlike micelles, vesicles, coacervates, and other aggregates. It aims at providing insightful understanding on how to select counterions for surfactants to achieve desired aggregate structures and properties.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103484"},"PeriodicalIF":15.9,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanism and design strategy of ice-phobic surface: A comprehensive review 疏冰表面的机理和设计策略：全面综述

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-21 DOI: 10.1016/j.cis.2025.103478

Tong Wang , Huimeng Feng , Lin Cao , Zhipeng Zhao , Wen Li , Shougang Chen

{"title":"Mechanism and design strategy of ice-phobic surface: A comprehensive review","authors":"Tong Wang , Huimeng Feng , Lin Cao , Zhipeng Zhao , Wen Li , Shougang Chen","doi":"10.1016/j.cis.2025.103478","DOIUrl":"10.1016/j.cis.2025.103478","url":null,"abstract":"<div><div>Ice accumulation on the surface can significantly impact the normal operation of industrial facilities and even lead to damage, resulting in economic losses. Modifying the physical structure and chemical state of the surface can effectively mitigate ice nucleation, growth, and adhesion processes. Building upon previous definitions of ice-phobic surfaces, this review provides a refined definition of ice-phobicity and reviews recent advancements in ice-phobic surfaces research. Firstly, ice-phobic mechanisms are summarized, which including principles of ice formation, theory of solid-liquid wettability of interface, and theory of solid-solid interface mechanics. Subsequently, strategies for developing near-term ice-phobic surfaces are discussed encompassing superhydrophobic surfaces, interfacial water induced surfaces, low adhesion surfaces, as well as thermal de-icing surfaces. Furthermore, a comparison is made regarding test detail definitions and commonly used test methods in researching ice-phobic surfaces to promote methodological uniformity. Lastly, the latest research findings on four distinct ice-phobic surfaces are highlighted, while also prospecting the challenges to be considered in future ice-phobic surface design.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103478"},"PeriodicalIF":15.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined treatment strategy of hydrogel dressing and physiotherapy for rapid wound healing

IF 15.9 1区化学

Advances in Colloid and Interface Science Pub Date : 2025-03-20 DOI: 10.1016/j.cis.2025.103477

Xiaofei Xie , Chenhui Zhu , Jing Zhao , Yanru Fan , Huan Lei , Daidi Fan

{"title":"Combined treatment strategy of hydrogel dressing and physiotherapy for rapid wound healing","authors":"Xiaofei Xie , Chenhui Zhu , Jing Zhao , Yanru Fan , Huan Lei , Daidi Fan","doi":"10.1016/j.cis.2025.103477","DOIUrl":"10.1016/j.cis.2025.103477","url":null,"abstract":"<div><div>Wound care for open wounds is essential for reducing pain, protecting open wounds, speeding up the healing process and avoiding scar formation. Among the various three-dimensional (3D) carrier biomaterials such as films, sponges, and hydrogels, hydrogels are chemically and physically most similar to the natural extracellular matrix (ECM). Meanwhile, hydrogels are also common 3D carriers that can be efficiently loaded with drugs or cells. In addition, it forms a protective barrier on the wound surface to prevent secondary external infections and has the effect of directing skin cell expansion, tissue infiltration, and wound closure. However, the role of functional drugs in wound healing also faces a number of issues such as resistance, dosage, activity, and stability; therefore, a richer array of therapies is needed for wound repair and other areas of development. Physiotherapy, also known as nonpharmacological therapy, is a commonly used clinical treatment. Recently, more and more physiotherapy have been used for wound repair due to their high efficiency and low irritation. In recent reports, many researchers have tended to use hydrogel dressings in combination with physiotherapy, and this combination therapy is beneficial because it can both protect the wound microenvironment and accelerates wound healing. Therefore, this paper reviews the combined use of hydrogel dressings and physiotherapy in wound healing. We present the characteristics of hydrogel and physiotherapy and focus on the progress and problems of these two combined therapies in recent years.</div></div>","PeriodicalId":239,"journal":{"name":"Advances in Colloid and Interface Science","volume":"341 ","pages":"Article 103477"},"PeriodicalIF":15.9,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0