Small Methods最新文献

{"title":"Improving HER2 Diagnostics with Digital Real-Time PCR for Ultrafast, Precise Prediction of Anti-HER2 Therapy Response in Patients with Breast Cancer.","authors":"Hee-Joo Choi, Soo Young Park, Minsik Song, Jinhyuk Chang, YoonSik Kim, Hosub Park, Chihwan David Cha, Sohyeon Yang, Nam Hun Heo, Min Ji Song, Da Sol Kim, Hayeon Kim, Minuk Kim, Jae Eun Park, Yesung Lee, EunChae Ji, Heekyoung Chung, Ilecheon Jeong, Mineui Hong, Jin-Wu Nam, Mee-Hye Oh, Ji-Hye Lee, Jinwoo Seol, Hee-Young Won, Hyun-Woo Song, Jaewon Eom, Do Young Lee, Han Suk Ryu, Si-Hyong Jang, Jeong-Yeon Lee","doi":"10.1002/smtd.202500599","DOIUrl":"https://doi.org/10.1002/smtd.202500599","url":null,"abstract":"<p><p>While human epidermal growth factor receptor (HER2) has emerged as a tumor-agnostic biomarker, standard HER2 testing for anti-HER2 therapies using immunohistochemistry (IHC) and in situ hybridization (ISH) assays remains subjective, time-consuming, and often inaccurate. To address these limitations, an ultrafast and precise HER2 testing method is developed using Lab-On-An-Array (LOAA) digital real-time PCR (drPCR), a fully automated digital PCR enabling real-time absolute quantification. A multicenter study involving four independent breast cancer cohorts cross-validates the high diagnostic accuracy of drPCR-based HER2 assessment. Comparative analyses with artificial intelligence algorithms, next-generation sequencing, and droplet digital PCR demonstrate that drPCR is faster, simpler, and more accurate than conventional assays for assessing HER2 status, while IHC/ISH frequently yields false positives. Importantly, in patients initially diagnosed as HER2-positive and treated with neoadjuvant anti-HER2 therapy, the HER2 drPCR(+)/IHC-ISH(+) group achieves high pathological complete response rates, while HER2 drPCR(-)/IHC-ISH(+) cases exhibit poor treatment responses, highlighting the superior predictive accuracy of drPCR for anti-HER2 therapy response. Additionally, drPCR identifies patients with chromosome 17 centromere abnormalities, HER2-zero/ERBB2 hemizygous deletion, and ERBB2 hyperamplification who respond favorably to anti-HER2 therapy. Collectively, these findings establish drPCR as a clinically feasible, standardized, and ultrafast HER2 testing method for improved prediction of anti-HER2 therapy response in patients with cancer.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e00599"},"PeriodicalIF":9.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electronic Structure of Ni-Based Reconstructed Surface for Electrocatalytic Alkaline Oxygen Evolution Reaction.","authors":"Zichao Shen, Ke Wang, Yutong Yuan, Fan Gao, Xinqiang Wang, Wengang Cui, Fulai Qi, Xiangrong Ren, Jian Chen, Chunhui Xiao, Hongge Pan","doi":"10.1002/smtd.202500736","DOIUrl":"https://doi.org/10.1002/smtd.202500736","url":null,"abstract":"<p><p>The sluggish kinetics of the oxygen evolution reaction (OER) in alkaline water electrolysis lead to high overpotentials, limiting cost-effective green hydrogen production. Ni-based catalysts, recognized as promising OER electrocatalysts, require electronic structure modulation to enhance performance. However, under oxidizing conditions, Ni-based materials undergo surface reconstruction with significant electronic alterations, rendering bulk-phase studies less practical. Recent efforts focus on regulating reconstructed surface electronic structures for improved efficiency, underscoring the need for a systematic review on this critical topic. This review highlights the fundamental progress regarding the electronic structure regulation of reconstructed surface of Ni-based OER electrocatalysts for better understanding the surface reconstruction process and the structure-activity relationship, including the basic understanding of OER mechanism and surface reconstruction of Ni-based materials, the principles and practical applications of key electronic structure descriptors with their respective advantages and limitations, and recent advancements and developing bottle-necks in surface reconstruction chemistry across diverse Ni-based OER catalyst systems. Finally, the challenges facing surface reconstruction of Ni-based OER catalysts are summarized, and several future prospects are proposed to guide the in-depth analysis of the reconstruction mechanism and the rational design of Ni-based OER catalysts.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2500736"},"PeriodicalIF":9.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conductive Hydrogel-Enabled Electrode for Scalp Electroencephalography Monitoring.","authors":"Zichong Ji, Leqi Li, Meiqiong Zheng, Xinyuan Ye, Wenqing Yan, Zonglei Wang, Yi Liu, Yuli Wang, Yujie Zhang, Pengcheng Zhou, Jiawei Yang, Mingzhe Wang, Shihong Lin, Hossam Haick, Yan Wang","doi":"10.1002/smtd.202501242","DOIUrl":"https://doi.org/10.1002/smtd.202501242","url":null,"abstract":"<p><p>Scalp electroencephalography (EEG) serves as a pivotal technology for the noninvasive monitoring of brain functional activity, diagnosing neurological disorders, and assessing cognitive states. However, inherent compatibility barriers between traditional rigid electrodes and the hairy scalp interface significantly compromise signal quality, long-term monitoring comfort, and user compliance. This review examines conductive hydrogel electrodes' pivotal role in advancing scalp EEG, particularly their unique capacity to overcome hair-interface barriers. The superiority of scalp EEG is first established over forehead/ear EEG for capturing diverse neural signals and defining core requirements for hair-compatible interfaces: scalp conformability, electrical conductivity, low contact impedance, and interfacial stability. Conductive hydrogel electrode applications are then detailed in alpha wave detection, sleep monitoring, event-related potential studies, and brain-computer interfaces. Finally, persisting challenges and future opportunities are discussed.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01242"},"PeriodicalIF":9.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Record Open-Circuit Voltage in Perovskite/PERC Tandem Solar Cells via Novel a-Si Interlayer Passivation.","authors":"Young Im Noh, Chan Ul Kim, Youngseok Lee, Md Halim Hossain, Hyungju Ahn, Doh-Kwon Lee, Keunkee Hong, Inho Kim, Kyoung Jin Choi","doi":"10.1002/smtd.202500808","DOIUrl":"https://doi.org/10.1002/smtd.202500808","url":null,"abstract":"<p><p>Monolithic perovskite/silicon tandem (PST) solar cells are rapidly emerging as next-generation solar cells with significant potential for commercialization. This study presents a proof of concept for a silicon diffused junction-based PST cell, utilizing a passivated emitter rear contact (PERC) cell with a low-temperature (<200 °C) laser-fired contact process to minimize thermal damage. By introducing amorphous silicon to the emitter surface of PERC bottom cell, the open circuit voltage (V_oc) improve from 0.58 V to 0.61 V due to the passivation effect, which reduces silicon surface recombination. Perovskite is passivated using ammonium salts with varying alkyl chain lengths, including n-Butylammonium bromide, n-Hexylammonium bromide, and n-Octylammonium bromide (OABr). OABr is the most effective, increasing the V_oc of the perovskite top cell from 1.18 V to 1.22 V by reducing non-radiative recombination. The best-performing PST cell achieves a power conversion efficiency (PCE) of 25.71%, with a current density of 17.62 mA cm^- ², V_oc of 1.810 V, and fill factor of 80.62%. This represents the highest V_oc and PCE reported for PST cells with PERC-based p-type silicon bottom cell technology. Even after 1000 hours of damp heat testing at 85 °C and 85% relative humidity, the device with dual passivation maintained 90.70% of its initial PCE.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e00808"},"PeriodicalIF":9.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural Flexibility of Hydrated RHO Nanosized Zeolite Synthesized via Green Synthesis Approach at Subfreezing Conditions.","authors":"Sajjad Ghojavand, Giorgia Confalonieri, Stoyan P Gramatikov, Edwin B Clatworthy, Aymeric Magisson, Diógenes Honorato Piva, Francesco Dalena, Riccardo Fantini, Rossella Arletti, PetkoSt Petkov, Georgi N Vayssilov, Svetlana Mintova","doi":"10.1002/smtd.202501376","DOIUrl":"https://doi.org/10.1002/smtd.202501376","url":null,"abstract":"<p><p>Understanding the structural flexibility of zeolites under cryogenic conditions is essential for optimizing gas separation and storage performance. This study investigates nanosized RHO zeolite synthesized via green synthesis (without organic structural directing agent) upon hydration and cooling to low temperatures (<273 K) using in situ XRPD, in situ FTIR spectroscopy, and DFT simulations. Template-free synthesis is performed at low temperature (363 K), avoiding calcination or postsynthetic activation, yielding highly crystalline nanosized zeolite with minimal energy consumption and no toxic by-products. Upon hydration at 300 K, nanosized RHO zeolite adopts a two-phase expanded-contracted structure due to distinct water-cation interactions. Upon cooling to 248 K, the hydrated zeolite transitions into a single expanded phase, remaining stable after reheating to 300 K, forming a metastable state. In situ FTIR analysis indicates freezing-induced water molecule rearrangement leads to persistent hydrogen-bonding networks, preventing structural reversion. This metastable state exhibits CO₂ adsorption capacities comparable to conventionally activated RHO zeolite (623 K), achieved through significantly lower energy input. This performance underscores the viability of mild, green chemistry-aligned activation approaches eliminating energy-intensive high-temperature treatments. This novel approach contributes to sustainable separation processes and provides a blueprint for future innovation in porous materials guided by green chemistry principles.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01376"},"PeriodicalIF":9.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stimuli-Responsive Nanomaterials for Wireless and Precise Neuromodulation.","authors":"Yamin Liu, Bowen Li, Dao Shi, Ruixue Xiao, Heemin Kang, Fangyuan Li, Daishun Ling","doi":"10.1002/smtd.202501275","DOIUrl":"https://doi.org/10.1002/smtd.202501275","url":null,"abstract":"<p><p>Neuromodulation is a highly promising technology for controlling neural circuits, treating nervous system diseases, and manipulating brain function. Conventional approaches, such as direct electrical stimulation or optogenetics, face challenges from their unstable therapeutic outcomes, invasive nature, and potential tissue damage. The emergence of stimuli-responsive nanomaterial-based wireless neuromodulation techniques offers tunability, minimal invasiveness, highly specific targeting, and long-term biocompatibility and stability. In this review, recent advancements in stimuli-responsive nanomaterials activated by either external physical stimuli or internal biological cues for neuromodulation, including energy conversion materials, artificial catalytic nanomaterials, neuro-bioactive nanomaterials, and multifunctional nanomaterials, which have not been comprehensively covered in previous reviews, are highlighted. It begins with the significance of neuromodulation, and the conventional strategies employed for it. Subsequently, the intricate landscape of structural design, modulation mechanisms, and therapeutic outcomes of the related neurological disorders presented by these nanomaterials is navigated through. Finally, the challenges are outlined and illuminate the prospects within this field, aiming to steer future innovations in the design of more applicable nanomaterials for neuromodulation. It is anticipated that this systematic review will advance the development of next-generation wireless neuromodulation platforms, facilitating their clinical translation for neurological disorders.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01275"},"PeriodicalIF":9.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Sol-Gel Processed Spinel HTL Combined with an Amphiphilic Polymer Interlayer for Stable and Scalable Tin-perovskite Solar Modules.","authors":"Yin-Fai Wang, Wun-Yu Chen, Chien-Hung Chiang, Chun-Guey Wu","doi":"10.1002/smtd.202501127","DOIUrl":"https://doi.org/10.1002/smtd.202501127","url":null,"abstract":"<p><p>A new, readily accessible inorganic hole transporting material (HTM), Cu²⁺ doped SnCo₂O₄ (Cu-SCO), is developed for inverted tin-perovskite solar modules (TPSMs). To overcome the intrinsic defect of inorganic solid-state material Cu-SCO and potential interfacial incompatibility with TPsk, an amphiphilic neutral donor-acceptor copolymer (PTSN) is rationally designed as a surface/interface modification agent. TPSMs based on Cu²⁺ doped SnCo₂O₄ HTLs integrated with PTSN surface/interface modification achieved the highest conversion efficiency of 10.4%. In contrast, the conversion efficiencies of TPSMs based on Cu-SCO HTL without interface passivation or using conventional PEDOT:PSS HTL are 8.69% and 7.99%, respectively. A large-area, high-quality Cu-SCO film is fabricated using a simple and scalable sol-gel method, enabling favorable transparency and hole mobility. The amphiphilic PTSN comprises a hydrophobic iso-propyltriphenylamine (i-Pr-TPA) unit that contributes to hole transport, and a hydrophilic cyclopentadithiophene derivative bearing alkylamine side chains (CPDT-A), which assists hole extraction and transport to the Cu-SCO layer. The amine nitrogen and thiophene sulfur in PTSN can coordinate with metal ions in both TPsk and Cu-SCO, while the π-electrons from its aromatic backbone can further interact with Cu-SCO, as evidenced by IR and XPS spectroscopy. Functionally, PTSN serves as a co-HTL, interfacial cross-linker, and defect passivator for both the HTL and the perovskite absorber. Additional advantages of PTSN include its neutral character-eliminating ion migration issues-dense film formation due to the D-A copolymer structure, and strong substrate adhesion enabled by multiple anchoring groups. Moreover, its amphiphilic nature facilitates the formation of uniform, high-quality perovskite films via solution processing. This study highlights a promising strategy that combines the sol-gel process with a molecularly engineered interfacial layer, paving the way for utilizing a wide range of solution-processable inorganic HTLs in large-area tin-based perovskite photovoltaic devices with good efficiency and stability.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01127"},"PeriodicalIF":9.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Over 19% Efficiency Polymer Solar Cells Enabled by Selectively Tuning Bulkheterojunction Morphology via a Dual-Heating Strategy.","authors":"Yi Chen, Kun Li, Jing Zhang, Jichu Wu, Tiantian Zhu, Jinpeng Zhang, Haiyang Li, Yishi Wu, Donghong Yu, Chuanlang Zhan","doi":"10.1002/smtd.202501159","DOIUrl":"https://doi.org/10.1002/smtd.202501159","url":null,"abstract":"<p><p>Photovoltaic performance of bulkheterojunction (BHJ)-based organic solar cells is critically governed by morphologies of donor:acceptor blends as light-harvesting layers. However, ideal morphological control remains challenging due to the systems' complexity. In this work, a sequential dual-heating (DH) strategy is presented to precisely tailor the BHJ morphology in a D18-Cl:Y6 system, achieving a remarkable 19.23% power conversion efficiency with enhanced device stability. The DH approach integrates a warm solution (WS) deposition and follow-on solvent-vapor annealing (SVA) by using carbon disulfide (CS₂). The results show that the WS process enlarges π-π distance, enhances photoluminescence, reduces energy loss, and accelerates hole transfer, while the subsequent SVA process increases π-π displacement, thereby reducing both bimolecular and trap-assisted recombination, balancing carrier mobilities, and accelerating hole transport as well. Sequential application of WS and SVA induces synergetic effects on the BHJ morphology by selectively suppressing lamellar ordering while enhancing π-π ordering, yielding simultaneous improvement in all key device parameters. The universal applicability of this approach is further validated through successful implementation in binary D18:Y6, D18-Cl:N3-BO, and ternary D18-Cl:D18:Y6 systems. The findings demonstrate this DH strategy as an effective pathway for precise BHJ morphology engineering, offering a new route for fabricating highly efficient and stable BHJ organic solar cells.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01159"},"PeriodicalIF":9.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fullerenes as Unique Modular Carbon Building Blocks for Advanced Electrocatalysis.","authors":"Wenhao Yang, Qi Huang, Ping Peng, Fang-Fang Li","doi":"10.1002/smtd.202501278","DOIUrl":"https://doi.org/10.1002/smtd.202501278","url":null,"abstract":"<p><p>Electrocatalytic reactions play a pivotal role in advancing sustainable energy technologies, particularly in the conversion of renewable resources into clean fuels. Achieving high-efficiency and durable electrocatalysts is essential for overcoming kinetic barriers in key processes. In this context, fullerenes have emerged as promising building blocks for catalyst design, owing to their unique structural and electronic characteristics. Unlike conventional carbon materials, fullerenes feature well-defined molecular frameworks, enabling precise modulation of active sites and facilitating structure-activity relationship studies. Their electron-buffering capacity enables dynamic modulation of active sites, while strong metal adsorption and spatial confinement facilitate the formation of stable, high-loading single-atom or cluster catalysts. Furthermore, their activated carbon cage surface allows flexible functionalization, offering a tunable platform for catalytic design. This review highlights the role of fullerenes in the rational design of next-generation electrocatalysts, providing mechanistic insights and recent advancements in fullerene-based systems.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01278"},"PeriodicalIF":9.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling Surface Reconstruction of MOF-Derived La, P-Co₃O₄ for Energy-Efficient Water and Urea Electrolysis.","authors":"Bharathi Arumugam, Pandian Mannu, Ranjith Kumar Darman, Ramkumar Vanaraj, Krishnapandi Alagumalai, Chi-Liang Chen, Tae Hwan Oh, Chung-Li Dong, Seong-Cheol Kim","doi":"10.1002/smtd.202500938","DOIUrl":"https://doi.org/10.1002/smtd.202500938","url":null,"abstract":"<p><p>Constructing robust electrocatalysts and shedding light on the processes of surface reconstruction is crucial for sustained hydrogen production and a deeper understanding of catalytic behavior. Here, a novel ZIF-67-derived lanthanum- and phosphorus-co-doped Co₃O₄ catalyst (La, P-Co₃O₄) has been reported. X-ray absorption spectroscopy (XAS) confirms that the La and P co-doping reduces the coordination number (CN), improves oxygen vacancies (O_v), and leads to lattice distortion. Soft XAS confirms that Co²⁺ exists predominantly in La, P-Co₃O₄ than in Co₃O₄. Investigation of surface reconstruction with in situ Raman spectroscopy_, revealing that La, P-Co₃O₄ reconstructs earlier into catalytically active γ-CoOOH during the oxygen evolution reaction (OER) process. As a result, La, P-Co₃O₄ exhibits commendable electrocatalytic performance with minimal overpotentials of 351 mV for the OER, 222 mV for the hydrogen evolution reaction (HER), and 1.46 V for the urea oxidation reaction (UOR) to achieve a current density of 50 mA cm^-2. A two-electrode electrolyzer using La, P-Co₃O₄ as anode and cathode, achieving 19.4% energy savings during urea electrolysis compared to overall water electrolysis while maintaining stability for 72 h. This study provides a new perspective for understanding the mechanism and co-doping impact on the physicochemical properties of spinel Co₃O₄ for sustainable energy conversion.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2500938"},"PeriodicalIF":9.1,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}