Small Methods最新文献_第10页

Rolling Circle Amplification Boosts Ultrasensitive Liquid Biopsy. 滚动圈放大提高超灵敏液体活检。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-13 DOI: 10.1002/smtd.202501156

Jiaen You, Yingying Tan, Defu Kong, Honglv Yang, Yixiao Huang, Junru Li, Chen Ji, Yongming Han, Kang He, Fengqin Li, Peifeng Liu

{"title":"Rolling Circle Amplification Boosts Ultrasensitive Liquid Biopsy.","authors":"Jiaen You, Yingying Tan, Defu Kong, Honglv Yang, Yixiao Huang, Junru Li, Chen Ji, Yongming Han, Kang He, Fengqin Li, Peifeng Liu","doi":"10.1002/smtd.202501156","DOIUrl":"https://doi.org/10.1002/smtd.202501156","url":null,"abstract":"Liquid biopsy is a minimally invasive and convenient diagnostic and monitoring method for diseases, involving the collection and analysis of samples such as blood, urine, and cerebrospinal fluid. However, due to the intricate matrix composition of biological samples, there remains a need for further enhancement of sensitivity and specificity in current liquid biopsy methods to adequately meet clinical requirements. Rolling circle amplification (RCA) is an efficient isothermal enzymatic reaction capable of rapidly producing numerous ultra-long single-stranded DNA molecules with repetitive sequences. By custom-designing the DNA template sequence, RCA can generate functional products that integrate with various functional groups, achieving signal amplification and output with exceptional specificity and sensitivity in liquid biopsy. In this review, the fundamental principles and classifications of RCA are first introduced. Then, the coupling strategies of RCA with various detection technologies are systematically summarized, along with their prospects and challenges of clinical applications that have not been addressed in previous reviews, and the recent developments of RCA-based biosensors in liquid biopsy are explored. Finally, the challenges associated with the integration of RCA in liquid biopsy are discussed and potential directions for future advancements are proposed.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01156"},"PeriodicalIF":9.1,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145051530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conductive and Semiconductive 2D Materials for Neural Interfaces, Biosensors, and Therapeutic Modulation. 用于神经接口、生物传感器和治疗调制的导电和半导体二维材料。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-12 DOI: 10.1002/smtd.202501330

Chan Jae Shin, Kihyun Lee, Logan Langford, Wubin Bai

{"title":"Conductive and Semiconductive 2D Materials for Neural Interfaces, Biosensors, and Therapeutic Modulation.","authors":"Chan Jae Shin, Kihyun Lee, Logan Langford, Wubin Bai","doi":"10.1002/smtd.202501330","DOIUrl":"https://doi.org/10.1002/smtd.202501330","url":null,"abstract":"Due to population aging, the surge in chronic diseases, and recent pandemics, healthcare is increasingly shifting from hospital-centered models toward digital care. However, widespread adoption is impeded by signal degradation under physiological motion, biofouling, stringent power and data constraints. Effectively overcoming these challenges will require clinically robust devices providing precise, reliable, and reproducible performance. 2D materials address these demands through high carrier mobility that can improve signal-to-noise ratios, low-defect lattices for uniformity, and mechanical pliability that maintains intimate tissue contact and stable impedance during motion. These traits have fueled the rapid growth of 2D-material bioelectronics for remote care in lightweight, stretchable devices. This review surveys flexible, low-impedance neural electrodes of graphene, transition-metal dichalcogenides, and MXenes that integrate electrophysiological recording with optical imaging to provide high-resolution brain interfaces. It then examines their roles in biosensing and autonomous therapy, including sub-picomolar biomarker detection in complex fluids and photothermal, genetic, and antibacterial interventions. Open questions regarding long-term biocompatibility, scalable manufacturing, and protocol harmonization are highlighted. By aligning recent breakthroughs with persistent challenges, the review outlines the prospects of conductive and semiconductive 2D materials for neural interfacing, biosensing, and therapeutic delivery, and maps a pathway toward practical clinical translation.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01330"},"PeriodicalIF":9.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145038775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Additive-Free Crystallization Modulation for Efficient Perovskite Solar Cells by a Transverse Pulsed Electric Field. 横向脉冲电场对高效钙钛矿太阳能电池的无添加剂结晶调制。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-11 DOI: 10.1002/smtd.202501431

Hai-Fang Li, Pengkun Zhu, Zhiyu Zhang, Xin Sun, Shuailin Chen, Teng Xu, Bingbing Fan, Peng Cui, Liang Li, Lihua Chu, Meicheng Li

{"title":"Additive-Free Crystallization Modulation for Efficient Perovskite Solar Cells by a Transverse Pulsed Electric Field.","authors":"Hai-Fang Li, Pengkun Zhu, Zhiyu Zhang, Xin Sun, Shuailin Chen, Teng Xu, Bingbing Fan, Peng Cui, Liang Li, Lihua Chu, Meicheng Li","doi":"10.1002/smtd.202501431","DOIUrl":"https://doi.org/10.1002/smtd.202501431","url":null,"abstract":"Controlling the migration and spatial distribution of ionic constituents during perovskite growth represents a powerful approach to modulate the crystallization process and achieve optimal film morphology. However, the well-controlled regulation of specific ionic species and its consequences for oriented growth and defect suppression have received limited attention. Herein, a transverse pulsed electric field (e-field) is introduced to guide the directional migration of perovskite constituents, offering an alternative to crystallization control that is typically achieved with chemical additives. The MAPbI3 (where MA+ is CH3NH3 +) films exhibit a lateral gradient in iodine species distribution, which correlates with improved crystal orientation, decreased iodide loss, and reduced formation of iodide vacancies. The e-field-assisted thermal annealing enables the facile migration of unanchored iodides in perovskite films, allowing mobile I- ions to fill vacancies and passivate undercoordinated Pb2+ sites. This e-field-driven ion migration and self-filling of iodide vacancies in MAPbI3 could mitigate iodine-related defects caused by iodine loss and lower non-radiative recombination, leading to perovskite solar cells with improved efficiency and stability. Furthermore, this strategy is adaptable to the perovskites with mixed A-site cations and halides, delivering an efficiency of over 24%. These results provide new insights into defect self-passivation mediated with controlled e-field for high-performance devices.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01431"},"PeriodicalIF":9.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electron Paramagnetic Resonance Spectroscopy in Carbon Materials for Energy Storage: A Review. 碳储能材料的电子顺磁共振波谱研究进展

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-11 DOI: 10.1002/smtd.202501362

Yan Zhang, Yi Wan, Deyu Kong, Yujie Xu, Jinhao Pan, Qiang Li, Bin Wang, Mingbo Wu, Han Hu

{"title":"Electron Paramagnetic Resonance Spectroscopy in Carbon Materials for Energy Storage: A Review.","authors":"Yan Zhang, Yi Wan, Deyu Kong, Yujie Xu, Jinhao Pan, Qiang Li, Bin Wang, Mingbo Wu, Han Hu","doi":"10.1002/smtd.202501362","DOIUrl":"https://doi.org/10.1002/smtd.202501362","url":null,"abstract":"Given that carbon-based materials serve as the crucial electrode materials in electrochemical energy storage devices, it is of significance to comprehensively understand their energy storage mechanisms and optimize the performance of electrodes. In recent years, a diverse array of characterization techniques, including synchrotron radiation, have been employed to elucidate the complex structure-property relationships in these carbon electrodes. Among these techniques, electron paramagnetic resonance (EPR) spectroscopy stands out due to its high sensitivity to unpaired electrons, making it a powerful tool for characterizing the electronic structures of complex carbons and tracking electron transfer characteristics at the carbon electrode/electrolyte interface during electrochemical processes. In this review, the spectral differences resulting from molecular structural variations in carbon materials used for energy storage are systematically explored and the storage mechanisms based on ex situ analyses are interpreted. The significant advancements in in situ electrochemical characterization using EPR technology, providing new insights into the behavior of carbon electrodes are highlighted. Additionally, the current challenges facing EPR spectroscopy in the context of carbon-based energy storage are discussed and potential solutions are proposed. This review aims to serve as a valuable resource for understanding the complex structures and energy storage mechanisms of carbon materials through EPR spectroscopy.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01362"},"PeriodicalIF":9.1,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phase-Controlled Multi-Element Oxide-Sulfide Heterostructure Toward High-Efficiency Electro-Fenton Oxidation. 面向高效电fenton氧化的相控多元素氧化物-硫化物异质结构。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-10 DOI: 10.1002/smtd.202501652

Yemima Purba, Fitri Nur Indah Sari, Xuan-Yu Wei, Yen-Hsun Su, Jyh-Ming Ting

{"title":"Phase-Controlled Multi-Element Oxide-Sulfide Heterostructure Toward High-Efficiency Electro-Fenton Oxidation.","authors":"Yemima Purba, Fitri Nur Indah Sari, Xuan-Yu Wei, Yen-Hsun Su, Jyh-Ming Ting","doi":"10.1002/smtd.202501652","DOIUrl":"https://doi.org/10.1002/smtd.202501652","url":null,"abstract":"Electron Fenton (EF) degradation often suffers from low in situ H2O2 electrosynthesis and Fe2+ regeneration. Herein, a novel multi-element oxide-sulfide heterostructure is reported, (FeVCoCuMn)2O3/(CuFeVCoMn)S, for efficient and stable EF degradation. The oxide-sulfide phase ratio is optimized through temperature control during the synthesis. Experimental data and theoretical calculations highlight the advantages of multi-metal doping in enhancing the H2O2 selectivity and Fe2⁺ regeneration. The multi-element oxide-sulfide heterostructure outperforms its subsystems by providing enhanced H2O2 electrosynthesis. Among the elements, the Cu, Co, Mn, V, and S donate electrons to the trivalent Fe3⁺ cations, thus enhancing the Fe2⁺ regeneration. Density functional theory calculations show that the characteristics of the heterostructure can be optimized based on the phase ratio, resulting in enhanced charge transfer and optimized intermediate binding strength. The (FeVCoCuMn)2O3/(CuFeVCoMn)S catalyst achieves 98% tetracycline degradation in 120 min and maintains 87% efficiency over ten cycles. This work provides an insight into the coexistence of multi-metal doping and heterostructure in obtaining an efficient and selective heterogeneous EF catalyst for wastewater treatment.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01652"},"PeriodicalIF":9.1,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of High-Entropy Materials in Promoting Electrocatalytic Nitrogen Cycle. 高熵材料在促进电催化氮循环中的应用。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-09 DOI: 10.1002/smtd.202501303

Yiwen Su, Shurong Li, XinZhong Wang, Jiashu Chen, Fujing Xu, Lehlogonolo Rudolf Kanyane, Nicholus Malatji, Jing Yang, Guangping Zheng

{"title":"Application of High-Entropy Materials in Promoting Electrocatalytic Nitrogen Cycle.","authors":"Yiwen Su, Shurong Li, XinZhong Wang, Jiashu Chen, Fujing Xu, Lehlogonolo Rudolf Kanyane, Nicholus Malatji, Jing Yang, Guangping Zheng","doi":"10.1002/smtd.202501303","DOIUrl":"https://doi.org/10.1002/smtd.202501303","url":null,"abstract":"Nitrogen cycle is a fundamental biogeochemical loop existed for millions of years, which involves the transformation of nitrogen-containing chemicals in the environment. However, human activities, especially those since the Industrial Revolution, have significantly disrupted this balance, leading to environmental and energy challenges. Electrocatalysis nitrogen cycle (ENC) offers a promising alternative for the sustainable transformation of nitrogen compounds en route toward rebalancing, with reactions such as the electrocatalytic nitrogen reduction reaction (eNRR) and nitrate/nitrite reduction reaction (eNO3RR/eNO2RR) emerging as sustainable alternatives to the traditional Haber-Bosch process. However, conventional catalysts are handicapped by instability and linear scaling relationships. High-entropy materials (HEM), characterized by a high entropy of mixing due to the presence of multiple principal elements in nearly equal proportions, have garnered significant attention due to the synergistic effects among different elements, making them attractive candidates for applications in ENC. This review delves into the realm of HEMs and their applications in ENC, which elucidates the nitrogen cycle, the issues of conventional catalysts, definition of HEMs, and their employment in the ENC process. Critical characterizations, especially in situ technologies, are highlighted, and the prospects in this emerging field are discussed. This review could be a reference for future development of HEMs in catalysis.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01303"},"PeriodicalIF":9.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conductive Microneedle Patch with Mitochondria-Localized Generation of Nitric Oxide Promotes Heart Repair after Ischemia-Reperfusion Therapy. 线粒体定位生成一氧化氮的导电微针贴片促进缺血再灌注治疗后心脏修复。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-09 DOI: 10.1002/smtd.202500818

Yi-An Mao, Pingyuan Sun, Xiaohang Yin, Wensi Wan, Hang Chen, Xiya Wang, Renxiang Gui, Junwen Tang, Xiaozhou Shi, Yanjia Jin, Zihan Pan, Xu Wang, Tingting Yang, Hongdong Wang, Xuerui Chen, Junjie Xiao

{"title":"Conductive Microneedle Patch with Mitochondria-Localized Generation of Nitric Oxide Promotes Heart Repair after Ischemia-Reperfusion Therapy.","authors":"Yi-An Mao, Pingyuan Sun, Xiaohang Yin, Wensi Wan, Hang Chen, Xiya Wang, Renxiang Gui, Junwen Tang, Xiaozhou Shi, Yanjia Jin, Zihan Pan, Xu Wang, Tingting Yang, Hongdong Wang, Xuerui Chen, Junjie Xiao","doi":"10.1002/smtd.202500818","DOIUrl":"https://doi.org/10.1002/smtd.202500818","url":null,"abstract":"Timely blood resupply is a clinical strategy to treat myocardial infarction, which unavoidably causes myocardial ischemia-reperfusion injury. With disturbed electrical conduction and oxidative stress in infarcted myocardium, injured heart experiences a negative ventricle remodeling process, and finally leads to heart failure. Nitric oxide (NO) is a short-lived signaling molecule regulating cardiovascular homeostasis, while vasodilation of systemic vasculature is accompanied by its exogenous supplementation. Meanwhile, connexin 43 (Cx43), a gap junction protein for electrical propagation in myocardium, is downregulated by NO derived from inducible nitric oxide synthase (iNOS). The seesaw-like relationship of Cx43 and NO in cardiac repair raises an intractable issue of how to address localized-specific NO administration and simultaneously reconstruct electrical conduction. Given that both iNOS accumulation and NO metabolism affected by oxidative stress occur in mitochondria, mitochondria-specific l-arginine (l-Arg) delivery systems are developed and are encapsulated in conductive microneedle patches. When implanted onto myocardium, l-Arg is catalyzed by iNOS to synthesize NO in mitochondria, which contributes to sustained NO administration and alleviates oxidative stress. Functional patch with equivalent conductivity to myocardium repairs electrophysiological properties of heart and upregulates Cx43 expression. This study proposes integration of in situ NO generation and electrical conduction reconstruction in cardiac repair.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e00818"},"PeriodicalIF":9.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetic Implantable Devices and Materials for the Brain. 脑部磁性植入装置与材料。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-09 DOI: 10.1002/smtd.202501460

Xinyan Chen, Denghua Wu, Kangle Li, Mengdi Han

{"title":"Magnetic Implantable Devices and Materials for the Brain.","authors":"Xinyan Chen, Denghua Wu, Kangle Li, Mengdi Han","doi":"10.1002/smtd.202501460","DOIUrl":"https://doi.org/10.1002/smtd.202501460","url":null,"abstract":"Understanding the brain's complexity and developing treatments for its disorders necessitates advanced neural technologies. Magnetic fields can deeply penetrate biological tissues-including bone and air-without significant attenuation, offering a compelling approach for wireless, bidirectional neural interfacing. This review explores the rapidly advancing field of magnetic implantable devices and materials designed for modulation and sensing of the brain. Key modulation strategies include: magnetoelectric (ME) materials that convert magnetic into electric fields for stimulation; magnetothermal (MT) effects, where heating of nanoparticles activates thermosensitive ion channels; and magnetomechanical (MM) approaches that use magnetic forces to gate mechanosensitive channels. Methods for magnetic-based detection encompass: implantable magnetoresistive probes for the reference-free measurement of weak local neural magnetic fields; magnetic resonance needles that enhance metabolic profiling; and magnetoelastic systems where external magnetic fields vibrate magnetic implants to sense biophysical and biochemical conditions. The breadth of these magnetic transduction mechanisms promises future technologies that provide less invasive and more precise methods for understanding and regulating brain function.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01460"},"PeriodicalIF":9.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrafast Al³⁺ Conduction through Cooperative Bonding in Disordered Polycarbonate-Polyether Electrolytes. Al3 +在无序聚碳酸酯-聚醚电解质中通过协同键传导。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-09 DOI: 10.1002/smtd.202501397

Hongquan Pan, Changde Hu, Qiwen Sun, Zhanyu Li

{"title":"Ultrafast Al3⁺ Conduction through Cooperative Bonding in Disordered Polycarbonate-Polyether Electrolytes.","authors":"Hongquan Pan, Changde Hu, Qiwen Sun, Zhanyu Li","doi":"10.1002/smtd.202501397","DOIUrl":"https://doi.org/10.1002/smtd.202501397","url":null,"abstract":"As a new generation of high-energy-density energy storage system, solid-state aluminum-ion batteries have attracted much attention. Nowadays polyethylene oxide (PEO)-based electrolytes have been initially applied to Lithium-ion batteries due to their flexible processing and good interfacial compatibility, their application in aluminum-ion batteries still faces problems. To overcome the limitations in aluminum-ion batteries-specifically, strong Al3+ coordination suppressing ion dissociation, high room-temperature crystallinity, and inadequate mechanical strength-this study develops a blended polymer electrolyte (BPE) of polypropylene carbonate (PPC) and PEO. The PPC disrupts PEO crystallization, creating continuous amorphous channels that boost Al3+ mobility to 0.597 and enhance ionic conductivity. Simultaneously, rigid PPC chains form a dual-network structure with flexible PEO, increasing tensile strength to 672 kPa to effectively suppress aluminum dendrites. Crucially, PPC's carbonyl groups (─C═O) strongly adsorb Al3+ (-1.49 eV), partially displacing PEO's ether-oxygen coordination. This decouples ion pairs, elevates free Al3+ concentration, and improves interfacial kinetics. Consequently, Al//Al symmetric cells achieve stable 200-h cycling (0.1 mA cm-2, overpotential <0.4 V), and Al//benzo[i]benzo[6,7]quinoxalino[2,3,9,10]phenanthrol[4,5-abc]phenazine-5,10,16,21-tetraone (BQPT) cells retained 130 mAh g-1 after 120 cycles at 1 A g-1, demonstrating a promising high-safety electrolyte.","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e01397"},"PeriodicalIF":9.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145022560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioinspired DNA Framework-Programmed Heteroligation for Affinity-Enhanced Biodetection. 用于亲和增强生物检测的生物启发DNA框架编程异交。

IF 9.1 2区材料科学

Small Methods Pub Date : 2025-09-09 DOI: 10.1002/smtd.202500822

Shuai Yang, Chenghao Xi, Xiaolei Zuo, Min Li

引用次数: 0