Small Methods最新文献

{"title":"Machine Learning-Assisted Survey on Charge Storage of MXenes in Aqueous Electrolytes.","authors":"Kosuke Kawai, Yasunobu Ando, Masashi Okubo","doi":"10.1002/smtd.202400062","DOIUrl":"10.1002/smtd.202400062","url":null,"abstract":"<p><p>Pseudocapacitance is capable of both high power and energy densities owing to its fast chemical adsorption with substantial charge transfer. 2D transition-metal carbides/nitrides (MXenes) are an emerging class of pseudocapacitive electrode materials. However, the factors that dominate the physical and chemical properties of MXenes are intercorrelated with each other, giving rise to challenges in the quantitative assessment of their discriminating importance. In this perspective, literature data on the specific capacitance of MXene electrodes in aqueous electrolytes is comprehensively surveyed and analyzed using machine-learning techniques. The specific capacitance of MXene electrodes shows strong dependency on their interlayer spacing, where confined H₂O in the interlayer space should play a key role in the charge storage mechanism. The electrochemical behavior of MXene electrodes is overviewed based on atomistic insights obtained from data-driven approaches.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400062"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140287879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma Membrane-Derived Biomimetic Apoptotic Nanovesicles Targeting Inflammation and Cartilage Degeneration for Osteoarthritis.","authors":"Zongyi Li, Quhan Cheng, Luoyao Lin, Xiaoling Fu, Yingjun Wang","doi":"10.1002/smtd.202400660","DOIUrl":"10.1002/smtd.202400660","url":null,"abstract":"<p><p>Osteoarthritis (OA) is a degenerative whole-joint disease in which the synovium and joint cartilage become inflamed and damaged. The essential role of inflammation in the development of OA has been recognized recently. Accordingly, simultaneous regulation of local inflammation and tissue degeneration is proposed as a promising therapeutic strategy. Herein, multifunctional biomimetic apoptotic nanovesicles (Apo-NVs) are constructed with plasma membrane derived from apoptotic T cells. The anti-inflammatory microRNA-124 is further encapsulated into Apo-NVs in the hope of achieving an enhanced immunomodulatory effect. It is found that apoptotic nanovesicles, including Apo-NVs and Apo-NVs-miR-124, both efficiently promote the M2 repolarization of M1 macrophages and inhibit the degenerative phenotype of chondrocytes. Further in vivo studies show that Apo-NVs and Apo-NVs-miR-124 alleviate synovial inflammation and protect cartilage tissue from degeneration in OA mice. The study highlights the potential of Apo-NVs in treating OA and other inflammation-related diseases.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400660"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scalable Copper Sulfide Formulations for Super-Resolution Optoacoustic Brain Imaging in the Second Near-Infrared Window.","authors":"Lin Tang, Daniil Nozdriukhin, Sandeep Kumar Kalva, Quanyu Zhou, Çağla Özsoy, Shuxin Lyu, Michael Reiss, Anxo Vidal, Ana Torres, Xosé Luís Deán-Ben, Daniel Razansky","doi":"10.1002/smtd.202400927","DOIUrl":"10.1002/smtd.202400927","url":null,"abstract":"<p><p>Optoacoustic imaging offers label-free multi-parametric characterization of cerebrovascular morphology and hemodynamics at depths and spatiotemporal resolution unattainable with optical microscopy. Effective imaging depth can greatly be enhanced by employing photons in the second near-infrared (NIR-II) window. However, diminished absorption by hemoglobin along with a lack of suitable contrast agents hinder an efficient application of the technique in this spectral range. Herein, copper sulfide (CuS) micro- and nano-formulations for multi-scale optoacoustic imaging in the NIR-II window are introduced. Dynamic contrast enhancement induced by intravenously administered CuS nanoparticles facilitated visualization of blood perfusion in murine cerebrovascular networks. The individual calcium carbonate microparticles carrying CuS are further shown to generate sufficient responses to enable super-resolution microvascular imaging and blood flow velocity mapping with localization optoacoustic tomography.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400927"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142491781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoted Hydrogen Peroxide Production from Pure Water on g-C₃N₄ with Nitrogen Defects Constructed through Solvent-Precursor Interactions: Exploring a Complex Story in Piezo-Photocatalysis.","authors":"Phan Pham Duc Minh, Duc-Viet Nguyen, Minh Chien Nguyen, Nguyen Hoai Anh, Huynh Phuoc Toan, Pho Phuong Ly, Ngoc Linh Nguyen, Tiep Van Nguyen, Minh-Thuan Pham, Thuy Dieu Thi Ung, Do Danh Bich, Pham Thu Hue, Nguyen Thi Ngoc Hue, Van-Han Dang, Woo Jong Yu, Seung Hyun Hur, Quang Hung Nguyen, Luu Anh Tuyen, Hoai-Thanh Vuong","doi":"10.1002/smtd.202400797","DOIUrl":"10.1002/smtd.202400797","url":null,"abstract":"<p><p>Hydrogen peroxide (H₂O₂) production via oxygen (O₂) reduction reaction (ORR) in pure water (H₂O) through graphitic carbon nitrides (g-C₃N₄)-based piezo-photocatalysts is an exciting approach in many current studies. However, the low Lewis-acid properties of g-C₃N₄ limited the catalytic performance because of the low O₂ adsorption efficacy. To overcome this challenge, the interaction of g-C₃N₄ precursors with various solvents are utilized to synthesize g-C₃N₄, possessing multiple nitrogen-vacant species via thermal shocking polymerization. These results suggest that the lack of nitrogen in g-C₃N₄ and the incident introduction of oxygen-functional groups enhance the Lewis acid-base interactions and polarize the g-C₃N₄ lattices, leading to the enormous enhancement. Furthermore, the catalytic mechanisms are thoroughly studied, with the formation of H₂O₂ proceeding via radical and water oxidation pathways, in which the roles of light and ultrasound are carefully investigated. Thus, these findings not only reinforce the potential view of metal-free photocatalysts, accelerating the understanding of g-C₃N₄ working principles to generate H₂O₂ based on the oxygen reduction and water oxidation reactions, but also propose a facile one-step way for fabricating highly efficient and scalable photocatalysts to produce H₂O₂ without using sacrificial agents, pushing the practical application of in situ solar H₂O₂ toward real-world scenarios.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400797"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling Generally-ignored Co-substrate Effect of Catalase-inherent Peroxidase Mimic for Self-verifiable Detection of High-concentration Hydrogen Peroxide.","authors":"Haiwei Hou, Weijuan Jia, Aoxue Zhang, Minyang Su, Yazhong Bu, Lan Liu, Baoji Du","doi":"10.1002/smtd.202400847","DOIUrl":"10.1002/smtd.202400847","url":null,"abstract":"<p><p>One nanoparticle possessing both peroxidase (POD) and catalase (CAT) activities is a prevalent co-substrate nanozyme system, distinct from the extensively researched cascade nanozyme system. During the sensing of hydrogen peroxide by POD, the impact of CAT is actually ignored in most studies. In this study, the CAT effect on hydrogen peroxide detection is thoroughly investigated based on POD catalysis by finely tuning the relative activity of POD and CAT. It is discovered that the CAT effect can be changed by delaying the injection of chromogenic substrate after adding hydrogen peroxide and that the linear range grows with the delayed time. Then, a theoretical mechanism showed that the time-delay mediated CAT effect magnification does not change the V_max, but it causes K_m to linearly increase with delayed time, consistent with the experiment results. Furthermore, the detection of high concentrations of hydrogen peroxide is successfully realized in contact lens care solutions by utilizing time-delay-mediated POD/CAT nanozyme. On the other hand, its linear range-tunable characteristic is used to produce multiple standard curves, then enabled self-verifying hydrogen peroxide detection. Overall, this work investigates the role of CAT in CAT-inherent POD nanozymes both theoretically and experimentally, and confirms POD/CAT nanozyme's priority in developing high-performance sensors.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400847"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142102746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adsorption Dynamics of Disodium Octaborate Tetrahydrate on Clay Minerals: Implications for Construction Wood Protection.","authors":"Patrick Brisebois, Meriam Aouinti, Maziar Jafari, Mohamed Siaj, Claudiane Ouellet-Plamondon","doi":"10.1002/smtd.202400753","DOIUrl":"10.1002/smtd.202400753","url":null,"abstract":"<p><p>The wood preservative disodium octaborate tetrahydrate (DOT) migration is studied in clay. Using boron analysis by inductively coupled plasma optical emission spectroscopy (ICP-OES), DOT spatial and temporal dynamics are surveyed to show how DOT permeates into the wood and the clay using concentration profiles as a function of depth, initial wood moisture, and direction of filling. Atomic force microscopy and chemical imaging using photoinduced force microscopy are used to show the morphology of the wood samples and the distribution of DOT on their surface. ICP-OES results show that the average DOT concentration in the wood samples is originally 0.8 and 1.5 wt% in the bulk and at the surface, respectively. Conditioning of the wood to a moisture content of 19% in a climatic chamber reduces DOT concentration by 8% for the fir and 17% for the spruce. After one week of contact with the clays, the results showed a rapid decrease of 25-40% in DOT concentration in wood. On longer periods (5 months), the spruce shows a tendency to reabsorb the DOT from the clay and the DOT migration stabilizes at 20%. These results contribute to defining the dosage of DOT when the wood is exposed to clay.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400753"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microheater Controlled Crystal Phase Engineering of Nanowires Using In Situ Transmission Electron Microscopy.","authors":"Christopher R Y Andersen, Marcus Tornberg, Sebastian Lehmann, Daniel Jacobsson, Kimberly A Dick, Kristian S Mølhave","doi":"10.1002/smtd.202400728","DOIUrl":"10.1002/smtd.202400728","url":null,"abstract":"<p><p>Crystal Phase Quantum Dots (CPQDs) offer promising properties for quantum communication. How CPQDs can be formed in Au-catalyzed GaAs nanowires using different precursor flows and temperatures by in situ environmental transmission electron microscopy (ETEM) experiments is studied. A III-V gas supply system controls the precursor flow and custom-built micro electro-mechanical system (MEMS) chips with monocrystalline Si-cantilevers are used for temperature control, forming a micrometer-scale metal-organic vapor phase epitaxy (µMOVPE) system. The preferentially formed crystal phases are mapped at different precursor flows and temperatures to determine optimal growth parameters for either crystal phase. To control the position and length of CPQDs, the time scale for crystal phase change is investigated. The micrometer size of the cantilevers allows temperature shifts of more than 100 °C within 0.1 s at the nanowire growth temperature, which can be much faster than the growth time for a single lattice layer. For controlling the crystal phase, the temperature change is found to be superior to precursor flow, which takes tens of seconds for the crystal phase formation to react. This µMOVPE approach may ultimately provide faster temperature control than bulk MOVPE systems and hence enable engineering sequences of CPQDs with quantum dot lengths and positions defined with atomic precision.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400728"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142277647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-Effective Synthesis Method: Toxic Solvent-Free Approach for Stable Mixed Cation Perovskite Powders in Photovoltaic Applications.","authors":"Balagowtham Nambiraj, Acchutharaman Kunka Ravindran, Senthil Pandian Muthu, Ramasamy Perumalsamy","doi":"10.1002/smtd.202400768","DOIUrl":"10.1002/smtd.202400768","url":null,"abstract":"<p><p>Organometallic lead halide perovskite powders have gained widespread attention for their intriguing properties, showcasing remarkable performance in the optoelectronic applications. In this study, formamidinium lead iodide (α-FAPbI₃) microcrystals (MCs) is synthesized using retrograde solubility-driven crystallization. Additionally, methylammonium lead bromide (MAPbBr₃) and cesium lead iodide (δ-CsPbI₃) MCs are prepared through a sonochemical process, employing low-grade PbX₂ (X = I & Br) precursors and an eco-friendly green solvent (γ-Valerolactone). The study encompasses an analysis of the structural, optical, thermal, elemental, and morphological characteristics of FAPbI_3, MAPbBr₃, and CsPbI₃ MCs. Upon analysing phase stability, a phase transition in FAPbI₃ MCs is observed after 2 weeks. To address this issue, a powder-based mechanochemical method is employed to synthesize stable mixed cation perovskite powders (MCPs) by subjecting FAPbI₃ and MAPbBr₃ MCs with varying concentrations of CsPbI₃. Furthermore, the performance of mixed cation perovskites are examined using the Solar Cell Capacitance Simulator (SCAPS-1D) software. The impact of cesium incorporation in the photovoltaic characteristics is elucidated. All mixed cation absorbers exhibited optimal device performance with a thickness ranging between 0.6-1.5 µm. It's worth noting that the MCPs exhibit impressive ambient stability, remaining structurally intact and retaining their properties without significant degradation for 70 days of ambient exposure.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400768"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141454297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flexible Perovskite Solar Cells: A Futuristic IoTs Powering Solar Cell Technology, Short Review.","authors":"Jai Prakash Tiwari","doi":"10.1002/smtd.202400624","DOIUrl":"10.1002/smtd.202400624","url":null,"abstract":"<p><p>The perovskite solar cells (PSCs) technology translated on flexible substrates is in high demand as an alternative powering solution to the Internet of Things (IOTs). An efficiency of ∼26.1% on rigid and ∼25.09% on flexible substrates has been achieved for the PSCs. Further, it is also reported that F-PSC modules have a surface area of ∼900 cm², with a PCE of ∼16.43%. This performance is a world record for an F-PSC device more significant than ∼100 cm². The process optimization, and use of new transport materials, interface, and compositional engineering, as well as passivation, have helped in achieving such kind of performance of F-PSCs. Hence, the review focuses mainly on the progress of F-PSCs and the low-temperature fabrication methods for perovskite films concerning their full coverage, morphological uniformity, and better crystallinity. The transmittance, band gap matching, carrier mobility, and ease of low-temperature processing are the key figures of merit of interface layers. Electrode material's flexible and transparent nature has enhanced the device's mechanical stability. Stability, flexibility, and scalable F-PSC fabrication challenges are also addressed. Finally, an outlook on F-PSC applications for their commercialization based on cost will also be discussed in detail.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400624"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142102743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism and Control Strategies of Lithium-Ion Battery Safety: A Review.","authors":"Tingrun Lai, Hong Zhao, Youzhi Song, Li Wang, Yude Wang, Xiangming He","doi":"10.1002/smtd.202400029","DOIUrl":"10.1002/smtd.202400029","url":null,"abstract":"<p><p>Lithium-ion batteries (LIBs) are extensively used everywhere today due to their prominent advantages. However, the safety issues of LIBs such as fire and explosion have been a serious concern. It is important to focus on the root causes of safety accidents in LIBs and the mechanisms of their development. This will enable the reasonable control of battery risk factors and the minimization of the probability of safety accidents. Especially, the chemical crosstalk between two electrodes and the internal short circuit (ISC) generated by various triggers are the main reasons for the abnormal rise in temperature, which eventually leads to thermal runaway (TR) and safety accidents. Herein, this review paper concentrates on the advances of the mechanism of TR in two main paths: chemical crosstalk and ISC. It analyses the origin of each type of path, illustrates the evolution of TR, and then outlines the progress of safety control strategies in recent years. Moreover, the review offers a forward-looking perspective on the evolution of safety technologies. This work aims to enhance the battery community's comprehension of TR behavior in LIBs by categorizing and examining the pathways induced by TR. This work will contribute to the effective reduction of safety accidents of LIBs.</p>","PeriodicalId":229,"journal":{"name":"Small Methods","volume":" ","pages":"e2400029"},"PeriodicalIF":10.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141282537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}