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Efficacy of pharmacological interventions for ADHD: protocol for an updated systematic review and dose-response network meta-analysis. 药物干预多动症的疗效:最新系统综述和剂量反应网络荟萃分析方案。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-12 DOI: 10.1186/s13643-024-02675-1
Mikail Nourredine, Lucie Jurek, Georgia Salanti, Andrea Cipriani, Fabien Subtil, Orestis Efthimiou, Tasnim Hamza, Samuele Cortese
{"title":"Efficacy of pharmacological interventions for ADHD: protocol for an updated systematic review and dose-response network meta-analysis.","authors":"Mikail Nourredine, Lucie Jurek, Georgia Salanti, Andrea Cipriani, Fabien Subtil, Orestis Efthimiou, Tasnim Hamza, Samuele Cortese","doi":"10.1186/s13643-024-02675-1","DOIUrl":"10.1186/s13643-024-02675-1","url":null,"abstract":"<p><strong>Background: </strong>Attention-deficit/hyperactivity disorder (ADHD) affects approximately 5% of children globally, with symptoms often persisting into adulthood. While pharmacological interventions are commonly employed for management, understanding the optimal dosing for efficacy and tolerability remains crucial. This study aims to conduct a dose-response network meta-analysis to estimate the efficacy of pharmacological treatments across different doses, aiming to inform clinical decision-making and improve treatment outcomes.</p><p><strong>Methods: </strong>This updated systematic review will include randomized controlled trials evaluating ADHD medication efficacy in children, adolescents, and adults. An updated search from a 2018 NMA will be conducted across multiple electronic databases with no language restrictions, using specific eligibility criteria focused on randomized controlled trials. The primary outcome will assess the severity of ADHD core symptoms, while secondary outcomes will consider treatment tolerability. A dose-response Bayesian hierarchical model will be used to estimate dose-response curves for each medication, identifying optimal dosing strategies.</p><p><strong>Discussion: </strong>With this dose-response network meta-analysis, we aim to better understand the dose-response relationship of pharmacological treatment in ADHD, which could help clinician to the identification of optimal doses.</p><p><strong>Systematic review registration: </strong>OSF https://doi.org/10.17605/OSF.IO/3MY4A .</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"256"},"PeriodicalIF":6.3,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11470584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Teledermatology: an evidence map of systematic reviews. 远程皮肤病学:系统回顾证据图。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-12 DOI: 10.1186/s13643-024-02655-5
Aloysius Chow, Helen Elizabeth Smith, Lorainne Tudor Car, Jing Wen Kong, Kay Wee Choo, Angeline Ai Ling Aw, Marie Ann Mae En Wong, Christian Apfelbacher
{"title":"Teledermatology: an evidence map of systematic reviews.","authors":"Aloysius Chow, Helen Elizabeth Smith, Lorainne Tudor Car, Jing Wen Kong, Kay Wee Choo, Angeline Ai Ling Aw, Marie Ann Mae En Wong, Christian Apfelbacher","doi":"10.1186/s13643-024-02655-5","DOIUrl":"10.1186/s13643-024-02655-5","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Although the number of teledermatology studies is increasing, not all variables have been researched in equal depth, so there remains a lack of robust evidence for some teledermatology initiatives. This review describes the landscape of teledermatology research and identifies knowledge gaps and research needs. This evidence map can be used to inform clinicians about the current knowledge about teledermatology and guide researchers for future studies.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Our evidence map was conducted according to the Campbell Collaboration checklist for evidence and gap maps. Eight databases were searched (CINAHL, Embase, PubMed, Scopus, Web of Science, Cochrane Library, JBI Database of Systematic Reviews and Implementation Reports, and OpenGray), and only included systematic reviews of teledermatology involving humans published in English; while excluding non-systematic reviews (i.e., abstracts, conference proceedings, editorials, commentaries, or letters). From 909 records, 14 systematic reviews published between 2004 and 2022 were included. Our analysis focused on the systematic reviews' characteristics, dermatological conditions studied, rate of overlap and quality assessment of primary studies reviewed, and main findings reported.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Teledermatology was reportedly comparable with clinic dermatology and generally accepted by patients as a mode of care delivery for dermatological conditions. However, there are concerns about privacy, communication, completeness of information transmitted, familiarity with the technology, and technical problems. Healthcare professionals were generally satisfied with teledermatology but found telemedicine consultations longer than face-to-face consultations, and less confident in asynchronous teledermatology than conventional consultations. Teledermatology was reportedly more cost-effective than clinic dermatology; especially considering the distance traveled by patients, referral volume to teledermatology, and clinic dermatology costs. Although patients and providers are satisfied with teledermatology, face-to-face dermatology has higher diagnostic and management accuracy. Teledermatology was also used for training medical professionals. Regarding the validity and reliability of teledermatology outcome measures, no significant discussions were found.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;COVID-19 spotlighted telemedicine in clinical care, and we must ensure telemedicine continually improves with robust research. Further research is necessary for establishing a standardized outcome set, enhancing accuracy, concordance, cost-effectiveness, and safety, comparing teledermatology with non-dermatologist care, examining its effectiveness in non-Western low and middle-income countries, and incorporating patient involvement for improved study design.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Systematic review registration: &lt;/strong&gt;https://www.researchregistry.com/ (Unique Iden","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"258"},"PeriodicalIF":6.3,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endovascular thrombectomy after anterior circulation large vessel ischemic stroke: an updated meta-analysis. 前循环大血管缺血性卒中后的血管内血栓切除术:最新荟萃分析。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-12 DOI: 10.1186/s13643-024-02670-6
Seraj Makkawi, Jawad I Bukhari, Hassan K Salamatullah, Osama A Alkulli, Abdulrahman E Alghamdi, Asim Bogari, Naif M Aloufi, Mohammed Albadri, Fay N Alnafisi, Saeed Alghamdi
{"title":"Endovascular thrombectomy after anterior circulation large vessel ischemic stroke: an updated meta-analysis.","authors":"Seraj Makkawi, Jawad I Bukhari, Hassan K Salamatullah, Osama A Alkulli, Abdulrahman E Alghamdi, Asim Bogari, Naif M Aloufi, Mohammed Albadri, Fay N Alnafisi, Saeed Alghamdi","doi":"10.1186/s13643-024-02670-6","DOIUrl":"10.1186/s13643-024-02670-6","url":null,"abstract":"<p><strong>Background: </strong>Endovascular thrombectomy (EVT) has emerged as the established standard of care for the treatment of anterior circulation large-vessel occlusion (LVO). However, its benefits remain unclear in specific patient populations. Herein, we present an updated systematic review and meta-analysis aimed at thoroughly assessing the effectiveness and safety of combining EVT with medical treatment (MT) compared with MT alone.</p><p><strong>Methods: </strong>This systematic review was performed in accordance with the PRISMA guideline. The MEDLINE, Embase, and Cochrane databases were systematically searched to identify relevant articles published until December 30, 2023. The inclusion criteria restricted articles to randomized clinical trials (RCTs). We pooled odds ratios (OR) and their respective 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Fifteen RCTs involving 3897 patients were included in the study. EVT plus MT was associated with a significant reduction in disability at 90 days (OR = 1.91, [1.61-2.26]), improved functional independence (modified Rankin Scale [mRS] 0-2) (OR = 2.19 [1.81-2.64]), excellent functional outcomes (mRS 0-1) (OR = 2.37, [1.45-3.87]), improved independent ambulation (mRS 0-3) (OR = 2.17, [1.75-2.69]), and higher rates of partial/complete recanalization (OR = 2.18, [1.66-2.87] compared with EVT. Efficacy outcomes for both large and small infarct cores were statistically favorable following EVT. Safety outcomes showed comparable rates, except for intracerebral and subarachnoid hemorrhage, which favored MT alone.</p><p><strong>Conclusion: </strong>This meta-analysis supports the use of EVT plus MT as the standard of care for acute ischemic stroke patients with LVO of any infarct core size, as it offers substantial improvements in functional outcomes and recanalization. Safety considerations, particularly the risk of hemorrhage, warrant careful patient selection. These findings provide valuable insights for optimizing stroke management protocols and enhancing patient outcomes.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"255"},"PeriodicalIF":6.3,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142475303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-management in young and middle-aged patients with hypertension: a systematic review and meta-synthesis of qualitative studies. 中青年高血压患者的自我管理:定性研究的系统回顾和元综合。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-05 DOI: 10.1186/s13643-024-02665-3
Ruiyao He, Fangxin Wei, Ziqi Hu, Aoli Huang, Yu Wang
{"title":"Self-management in young and middle-aged patients with hypertension: a systematic review and meta-synthesis of qualitative studies.","authors":"Ruiyao He, Fangxin Wei, Ziqi Hu, Aoli Huang, Yu Wang","doi":"10.1186/s13643-024-02665-3","DOIUrl":"10.1186/s13643-024-02665-3","url":null,"abstract":"<p><strong>Background: </strong>There has been a sharp increase in the prevalence of hypertension in young and middle-aged people at high risk of the disease. Despite the fact that good self-management can be effective in controlling blood pressure, patients do not perform well in this area, resulting in poor blood pressure control. It is therefore particularly important to gain a thorough understanding of patients' attitudes to self-management and the factors that influence them. The aim of this study was to synthesise the qualitative research on attitudes, motivations and challenges of self-management in young and middle-aged hypertensive patients, to analyse the synthesised results using the COM-B model and to propose appropriate improvement actions.</p><p><strong>Methods: </strong>From the time of construction until May 2023, the system searched PubMed, Web of Science, ProQuest, Embase, MEDLINE, CINAHL, PsyCINFO and CNKI databases. The analyses were carried out using a thematic synthesis approach to summarise the key findings. The findings were then mapped and analysed using the COM-B model.</p><p><strong>Results: </strong>A total of 11 studies were included, involving 250 patients between the ages of 18 and 64. Four themes with ten sub-themes were identified: Poor disease recognition (low disease perception, fuzzy disease knowledge); Barriers to doctor-patient interactions (short communication time, unmet knowledge needs, incomplete guidance for disease management); Living in a hostile environment (heavy workload, lack of companionship, ignorance of families); Expectations for a healthy body (responsibility of family roles, witness the cruelty of illness). Analysis of the composite results based on the COM-B model showed that low disease perceptions, barriers to doctor-patient interactions and life circumstances with enemies on all sides were the main challenges faced by young and middle-aged hypertensive patients, whereas the expectation of a healthy body was a motivation to promote self-management of blood pressure in patients.</p><p><strong>Conclusions: </strong>This study shows that family responsibilities are a particular motivator for self-management in young and middle-aged hypertensive patients. In response to the problems they face, we believe that meeting patients' knowledge needs, improving healthcare professionals' communication skills and valuing the role of community hospitals are effective ways to promote patient self-management. In the future, telemedicine, mobile healthcare and intelligent monitoring devices will provide a solution to reduce the burden on medical resources.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42018100810.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"254"},"PeriodicalIF":6.3,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11453001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effective community-based interventions to prevent and control infectious diseases in urban informal settlements in low- and middle-income countries: a systematic review. 中低收入国家城市非正规住区预防和控制传染病的有效社区干预措施:系统综述。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-04 DOI: 10.1186/s13643-024-02651-9
Sohana Shafique, Dipika Shankar Bhattacharyya, Iffat Nowrin, Foyjunnaher Sultana, Md Rayhanul Islam, Goutam Kumar Dutta, Mariam Otmani Del Barrio, Daniel D Reidpath
{"title":"Effective community-based interventions to prevent and control infectious diseases in urban informal settlements in low- and middle-income countries: a systematic review.","authors":"Sohana Shafique, Dipika Shankar Bhattacharyya, Iffat Nowrin, Foyjunnaher Sultana, Md Rayhanul Islam, Goutam Kumar Dutta, Mariam Otmani Del Barrio, Daniel D Reidpath","doi":"10.1186/s13643-024-02651-9","DOIUrl":"10.1186/s13643-024-02651-9","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The impact of rapid urbanization taking place across the world is posing variegated challenges. Especially in terms of communicable disease, the risk is more concentrated in urban poor areas where basic amenities are inadequate. This systematic review synthesizes evidence on the effective community-based interventions (CBIs) aimed at preventing and controlling infectious diseases among the urban poor in low- and middle-income countries (LMICs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This systematic review was conducted following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) guidelines. A comprehensive search across five major databases was conducted to capture literature on CBIs published between 2011 and 2021. Scientific articles of any design that reported any type of CBIs effective in preventing and controlling infectious diseases (tuberculosis, diarrhea, typhoid, dengue, hepatitis B and C, influenza, and COVID-19) were included. Screening and selection of studies were done by two pairs of independent researchers using the predefined eligibility criteria. The risk of bias in included studies was assessed using the modified checklist outlined in the Cochrane Handbook for Systematic Reviews of Interventions and Effective Public Health Practice Project (EPHPP). Analysis of effective CBIs was guided by the conceptual framework for integrated CBIs for neglected tropical diseases (NTDs), and narrative synthesis was carried out. Geographical restrictions were limited to LMICs and papers published in English.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Out of 18,260 identified papers, 20 studies met the eligibility criteria and were included in this review. Community-based screening and socio-economic support, community-based vector control, behavior change communication, capacity building of the community health workers (CHWs), health education, and e- and m-health interventions were found as effective CBIs. Diversified CBIs were found to be effective for specific diseases, including tuberculosis (TB), diarrhea, dengue, influenza and ARI, and hepatitis B and C. Bundling of interventions were found to be effective against specific diseases. However, it was difficult to isolate the effectiveness of individual interventions within the bundle. The socio-cultural context was considered while designing and implementing these CBIs.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The effectiveness of an intervention is inextricably linked to social context, stakeholder dimensions, and broader societal issues. System approach is recommended, emphasizing context-specific, multi-component interventions that address social determinants of health. Integrating these interventions with public health strategies and community involvement is crucial for sustainable outcomes. These findings can guide the design of future interventions for better prevention and control of communicable diseases in urban poor areas.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Systemat","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"253"},"PeriodicalIF":6.3,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11451040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142375997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuron-specific enolase for the differentiation between sepsis patients with or without encephalopathy in intensive care unit. 神经元特异性烯醇化酶用于区分重症监护室中伴有或不伴有脑病的败血症患者。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-02 DOI: 10.1186/s13643-024-02667-1
Jiyun Hu, Shucai Xie, Zhaoxin Qian, Lina Zhang
{"title":"Neuron-specific enolase for the differentiation between sepsis patients with or without encephalopathy in intensive care unit.","authors":"Jiyun Hu, Shucai Xie, Zhaoxin Qian, Lina Zhang","doi":"10.1186/s13643-024-02667-1","DOIUrl":"10.1186/s13643-024-02667-1","url":null,"abstract":"","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"251"},"PeriodicalIF":6.3,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11448102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term (24 weeks) treatment efficacy and safety of ruxolitinib cream in participants with vitiligo: a systematic review and meta-analysis. 对白癜风患者使用芦可利替尼乳膏的短期(24周)疗效和安全性:系统综述和荟萃分析。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-02 DOI: 10.1186/s13643-024-02653-7
Yuan Yuan, Yatong Zhang, Li Zheng, Xiaotong Gu, Shaohua Yu, Xuelin Sun
{"title":"Short-term (24 weeks) treatment efficacy and safety of ruxolitinib cream in participants with vitiligo: a systematic review and meta-analysis.","authors":"Yuan Yuan, Yatong Zhang, Li Zheng, Xiaotong Gu, Shaohua Yu, Xuelin Sun","doi":"10.1186/s13643-024-02653-7","DOIUrl":"10.1186/s13643-024-02653-7","url":null,"abstract":"<p><strong>Importance: </strong>Vitiligo is a chronic skin disorder causing depigmentation. There is a lack of evidence-based medical evidence regarding ruxolitinib efficacy and safety for vitiligo.</p><p><strong>Objective: </strong>To assess the efficacy and safety of ruxolitinib cream in the treatment of vitiligo.</p><p><strong>Methods: </strong>The databases of PubMed, Embase, and Cochrane Library were searched. The literature screening was independently conducted by two reviewers.</p><p><strong>Data extraction and synthesis: </strong>For continuous variables, weighted mean difference (WMD) along with a 95% confidence interval (CI) was performed. For dichotomous outcomes, we calculated the odds ratios (ORs) or risk ratios (RRs), and their corresponding 95% CIs. The certainty of evidence was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).</p><p><strong>Main outcomes and measures: </strong>Symptoms, quality of life, and safety were evaluated using various measures, including the Facial Vitiligo Area Scoring Index (F-VASI), Total Vitiligo Area Scoring Index (T-VASI), Facial Body Surface Area (F-BAS), Total Body Surface Area (T-BAS) and Treatment-emergent Adverse Events (TEAEs).</p><p><strong>Results: </strong>Three trials, involving a total of 830 participants from nine countries were included (female 388, 46.7%, male 442, 53.3%). The meta-analysis demonstrated a significant increase in the likelihood of participants achieving F-VASI75 (OR, 4.34 [95% CI 2.67-7.06]; high), F-VASI50 (OR 4.71 [95% CI 3.24-6.84]; high), T-VASI75 (OR 2.78 [95% CI 1.10-7.00]; moderate), and T-VASI50 (OR 4.47 [95% CI 2.52-7.92]; high) when compared ruxolitinib to vehicle. Ruxolitinib was associated with more lowered percentage change of F-VASI scores (MD - 32.79 [95% CI - 36.37 to - 29.21]; moderate), and T-VASI scores (MD - 20.22 [95% CI - 23.11 to - 17.33]; moderate) from baseline compared to vehicle. There may not be a significant difference in the occurrence of TEAEs between ruxolitinib and vehicle (RR 1.46 [95% CI 0.85-2.49]; high).</p><p><strong>Conclusions: </strong>The findings suggest that ruxolitinib cream holds promise as a treatment option for vitiligo. Further long-term studies are needed to assess its sustained efficacy and safety profile.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42023431112.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"250"},"PeriodicalIF":6.3,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11445846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social determinants of unmet need for primary care: a systematic review. 未满足初级保健需求的社会决定因素:系统综述。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-02 DOI: 10.1186/s13643-024-02647-5
Feben W Alemu, Jane Yuan, Seth Kadish, Surim Son, Sunbal Salim Khan, Safa M Nulla, Kathryn Nicholson, Piotr Wilk, Jane S Thornton, Shehzad Ali
{"title":"Social determinants of unmet need for primary care: a systematic review.","authors":"Feben W Alemu, Jane Yuan, Seth Kadish, Surim Son, Sunbal Salim Khan, Safa M Nulla, Kathryn Nicholson, Piotr Wilk, Jane S Thornton, Shehzad Ali","doi":"10.1186/s13643-024-02647-5","DOIUrl":"10.1186/s13643-024-02647-5","url":null,"abstract":"<p><strong>Background: </strong>Despite primary care being largely free at the point of delivery, many Canadians experience challenges in accessing the services they need. A systematic review was conducted to summarize the evidence on the level of unmet need for primary care in Canada and its social determinants.</p><p><strong>Methods: </strong>MEDLINE, Embase, Cochrane, and Web of Science databases were screened from inception to December 2023 using relevant search terms for primary care and unmet healthcare needs. Quantitative observational studies in the English language that included Canadian adults aged 18 years and older and focused on unmet needs for primary care were included. The risk of bias in the studies was assessed using either the Joanna Briggs Institute (JBI) critical appraisal checklist or the Newcastle-Ottawa Scale. The included studies were synthesized narratively.</p><p><strong>Results: </strong>Forty-six studies met the inclusion criteria for this review. Of the included studies, 96% were cross-sectional in design and 91% had low risk of bias. The prevalence of unmet need, mostly self-reported, varied between 6.6% and 25.2% in national studies. Social determinants of unmet needs were heterogeneous across studies. Findings suggest that unmet need for primary care is related to having low income, mental health diagnoses, and chronic conditions, and negatively associated with older age, having better-perceived health, and having a family physician.</p><p><strong>Conclusions: </strong>Universal access to primary care is the founding principle of the Canadian healthcare system. However, we found evidence suggesting that the extent to which primary care needs are met is influenced by social determinants of health. Further research is needed to improve our understanding of the mechanisms of unmet primary care needs in Canada.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42021285074.</p>","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"252"},"PeriodicalIF":6.3,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11448019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142366619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in scientific publishing: does quantity compromises quality in life sciences and medicine? 科学出版的趋势:生命科学和医学的数量是否会影响质量?
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-10-01 DOI: 10.1186/s13643-024-02668-0
Said El Shamieh, Alain Chebly
{"title":"Trends in scientific publishing: does quantity compromises quality in life sciences and medicine?","authors":"Said El Shamieh, Alain Chebly","doi":"10.1186/s13643-024-02668-0","DOIUrl":"10.1186/s13643-024-02668-0","url":null,"abstract":"","PeriodicalId":22162,"journal":{"name":"Systematic Reviews","volume":"13 1","pages":"249"},"PeriodicalIF":6.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11443745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between intraoperative hypothermia and postoperative delirium: a preliminary meta-analysis. 术中低体温与术后谵妄之间的关系:初步荟萃分析。
IF 6.3 4区 医学
Systematic Reviews Pub Date : 2024-09-30 DOI: 10.1186/s13643-024-02669-z
I-Wen Chen, Wei-Ting Wang, Kuo-Chuan Hung
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引用次数: 0
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