Pharmacy Education最新文献_第4页

Formulation of self-nanoemulsifying drug delivery system (SNEDDS) of combined 70% ethanolic of Begonia medicinalis herbs and Moringa oleifera leaves 海棠药材和油辣木叶 70%乙醇的自纳米乳化给药系统（SNEDDS）配方

IF 0.5

Pharmacy Education Pub Date : 2024-05-13 DOI: 10.46542/pe.2024.243.304309

Nur Asita, Muhammad Sulaiman Zubair, Y. Syukri, Evi Sulastri

{"title":"Formulation of self-nanoemulsifying drug delivery system (SNEDDS) of combined 70% ethanolic of Begonia medicinalis herbs and Moringa oleifera leaves","authors":"Nur Asita, Muhammad Sulaiman Zubair, Y. Syukri, Evi Sulastri","doi":"10.46542/pe.2024.243.304309","DOIUrl":"https://doi.org/10.46542/pe.2024.243.304309","url":null,"abstract":"Background: Benalu batu (Begonia medicinalis) and kelor leaves (Moringa oleifera) are empirically used as alternative therapies by people in Central Sulawesi to maintain their health. Our previous research showed that the combination of these two plant extracts possessed an immunomodulatory activity. Self-Nanoemulsifying Drug Delivery System (SNEDDS) formulation was performed to improve the extract's bioavailability, solubility and stability.\u0000Objective: This study aims to formulate and characterise SNEDDS preparations of combined ethanolic extract of B. medicinalis herbs and M. oleifera leaves and further test its stability.\u0000Method: SNEDDS formulation was started by screening for proper oil, surfactant, and co-surfactant. The formula was then optimised using a ternary phase diagram and characterisation. The stability test was performed using centrifugation, heating-cooling, and freeze-thaw cycles.\u0000Results: The optimal SNEDDS formula consists of isopropyl myristate (10%), tween 80 (50%) and propylene glycol (40%). The characterisation values obtained were: Transmittance value 83.785 ± 0.275%, particle size 18.666 ± 0.208 nm, polydispersity index 0.664 ± 0.0085, and zeta potential -39.20 ± 0.2 mV. The formula was stable during three stability evaluation tests.\u0000Conclusion: The optimal formula met the SNEDDS characteristics requirements and showed good stability.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140982201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drug utilisation study of parenteral nutrition in neonate patients 新生儿肠外营养药物使用研究

IF 0.5

Pharmacy Education Pub Date : 2024-05-13 DOI: 10.46542/pe.2024.243.310314

A. D. Puspitasari, Satya Andiva, Hargus Haraudi Barkah, Mahendra Tri Arif Sampurna, Budi Suprapti, Mariah Ulfa, Diah Sukmawati Pangarsih, Widia Yuniarti

{"title":"Drug utilisation study of parenteral nutrition in neonate patients","authors":"A. D. Puspitasari, Satya Andiva, Hargus Haraudi Barkah, Mahendra Tri Arif Sampurna, Budi Suprapti, Mariah Ulfa, Diah Sukmawati Pangarsih, Widia Yuniarti","doi":"10.46542/pe.2024.243.310314","DOIUrl":"https://doi.org/10.46542/pe.2024.243.310314","url":null,"abstract":"Background: The neonatal period is an individual adaptation with a higher risk of death and complications. Using parenteral nutrition to meet nutritional imbalances in neonates requires close supervision to prevent complications caused by inappropriate administration.\u0000Objective: This study aims to examine the effectiveness of parenteral nutrition (PN) in weight changes, patient caloric balance, osmolarity, and side effects.\u0000Methods: This study used a prospective observation method and was carried out from April to June 2023 at Universitas Airlangga Hospital. Data were obtained through medical records and direct observation of the patient’s condition after the patient’s parents signed an informed consent. Data analysis was carried out descriptively.\u0000Results: PN was given centrally or peripherally to 71 patients. Of those, 21 were low birth weight patients. Caloric balance was achieved in almost all patients. All patients gained weight, although only 20.89% experienced a return to birth weight. Phlebitis occurred in 35.22% of patients.\u0000Conclusion: Parenteral nutrition is efficacious in increasing the patient’s weight, depending on the suitability of the calculation between calories needed and calories obtained and the osmolarity of the preparation.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140983390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between knowledge and characteristics of patients with type 2 diabetes mellitus in controlling blood glucose 2 型糖尿病患者控制血糖的知识与特征之间的相关性

IF 0.5

Pharmacy Education Pub Date : 2024-05-12 DOI: 10.46542/pe.2024.243.298303

N. M. Ulfa, Suharjono, Andi Hermansyah

{"title":"Correlation between knowledge and characteristics of patients with type 2 diabetes mellitus in controlling blood glucose","authors":"N. M. Ulfa, Suharjono, Andi Hermansyah","doi":"10.46542/pe.2024.243.298303","DOIUrl":"https://doi.org/10.46542/pe.2024.243.298303","url":null,"abstract":"Background: Type 2 Diabetes mellitus (T2DM) is a non-communicable disease, with an estimated prevalence based on the International Diabetes Foundation (IDF) to increase by 46%. Community knowledge about T2DM is relatively low. Improving this level of knowledge is essential to reduce the prevalence of this disease.\u0000Objective: To determine the correlation between patients' knowledge and characteristics of T2DM.\u0000Method: Knowledge was measured using the Indonesian translation of the Diabetes Knowledge Questionnaire 24 (DKQ-24), which was distributed to 300 patients who met the inclusion criteria. This study used the cross-sectional method.\u0000Result: The results showed that the level of knowledge obtained high knowledge with a score of ≥ 12 in 151 patients (53%), while a low level of knowledge with a score of < 12 was in 149 patients (47%). Furthermore, there was a significant relationship between the level of knowledge and education, work, and blood glucose parameters. Furthermore, a high knowledge level was associated with better blood glucose control.\u0000Conclusion: This study concluded that knowledge and education determined the patient's glycemic control.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of anticoagulant drugs for hospitalised patients: A multicentre study 住院病人抗凝药物的使用：一项多中心研究

IF 0.5

Pharmacy Education Pub Date : 2024-05-12 DOI: 10.46542/pe.2024.243.286291

Lily Annisa, Nurfina Dian Kartikawati, V. Ningrum

{"title":"Use of anticoagulant drugs for hospitalised patients: A multicentre study","authors":"Lily Annisa, Nurfina Dian Kartikawati, V. Ningrum","doi":"10.46542/pe.2024.243.286291","DOIUrl":"https://doi.org/10.46542/pe.2024.243.286291","url":null,"abstract":"Background: Anticoagulants are indicated for several types of diseases with progression related to coagulation. Patients administered this drug need to be evaluated by the pharmacist regarding its effectiveness and possible side effects. \u0000Objective: This research aimed to analyse the profile use of anticoagulants among patients at Yogyakarta Hospital. \u0000Method: This research was a multicentre study conducted retrospectively using the medical records of inpatients who received anticoagulants. \u0000Result: Among a total of 486 respondents, the majority were male (63.58%), and the adult age category (18-59 years) was 55.76%. Most anticoagulants were used in cases of cardiovascular disease, diagnosed with NSTEMI as much as 20.21%. The most used anticoagulant drug was heparin (48.9%), followed by fondaparinux (34.3%) and enoxaparin (16.8%). The most duration of anticoagulant use was one to four days (73.02%) with the dose range being 200-1000 units/day. \u0000Conclusion: Heparin was the anticoagulant widely used in patients with NSTEMI. Although the elderly were the group most at risk of ADR due to anticoagulants, most of these drugs were precisely taken by adults, who also required serious attention. Further research is needed to provide a more comprehensive approach to anticoagulant therapy.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140987005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of factors causing stunting in Lamper Tengah primary healthcare centre, Semarang City 三宝垄市Lamper Tengah初级保健中心发育迟缓的原因识别

IF 0.5

Pharmacy Education Pub Date : 2024-05-12 DOI: 10.46542/pe.2024.243.273279

Firdha Fauzia, Gusti Noorrizka Veronika Achmad, Ana Yuda

{"title":"Identification of factors causing stunting in Lamper Tengah primary healthcare centre, Semarang City","authors":"Firdha Fauzia, Gusti Noorrizka Veronika Achmad, Ana Yuda","doi":"10.46542/pe.2024.243.273279","DOIUrl":"https://doi.org/10.46542/pe.2024.243.273279","url":null,"abstract":"Background: Stunting is a form of growth failure due to the accumulation of nutritional deficiencies characterised by height-for-age below the applicable standard. The prevalence of stunting in Indonesia in 2021 is 24.4%. In Semarang, the prevalence of stunting fluctuates. 2015, it was 14.4% and increased to 21% in 2017. Until 2021, the stunting rate in Semarang is 21.3%. The Semarang government has made various efforts, but the stunting rate has remained unchanged. \u0000Objective: This study aims to discover more about the factors that cause stunting in Semarang. \u0000Method: This research is qualitative research with a phenomenological approach. The data obtained in this study was from observation and interviews with mothers who have stunted children. \u0000Result: A total of 15 informants were selected using purposive sampling techniques. The analysis method used is a descriptive method with inductive analysis. \u0000Conclusion: The result showed maternal factors were inadequate nutrition intake, genetic factors, stress during pregnancy, and poverty. In comparison, the factors in children are low birth weight, repeated infections, children's difficulty eating, and micronutrient deficiency. The environmental factors are the home environment polluted with cigarette smoke and unhealthy home conditions, poor sanitation, and limited access to clean water, leading to repeated infections.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the four mg warfarin initiation dose in patients with cardiovascular disease 评估心血管疾病患者的四毫克华法林起始剂量

IF 0.5

Pharmacy Education Pub Date : 2024-05-12 DOI: 10.46542/pe.2024.243.292297

Eunice Marlene Sicilia Kundiman, Zahrah Tatta Ramadhanty, Budi Suprapti, M. Y. Alsagaff, B. S. Zulkarnain, W. Nilamsari

{"title":"Evaluation of the four mg warfarin initiation dose in patients with cardiovascular disease","authors":"Eunice Marlene Sicilia Kundiman, Zahrah Tatta Ramadhanty, Budi Suprapti, M. Y. Alsagaff, B. S. Zulkarnain, W. Nilamsari","doi":"10.46542/pe.2024.243.292297","DOIUrl":"https://doi.org/10.46542/pe.2024.243.292297","url":null,"abstract":"Background: Warfarin is the most widely used oral anticoagulant for the prevention of stroke in patients with cardiovascular disease. In Indonesia, validation of the initiation dose of warfarin has never been carried out.\u0000Objective: To evaluate the efficacy and safety of 4 mg warfarin initiation dose in achieving therapeutic targets.\u0000Methods: It was a prospective observational study involving hospitalised and ambulatory patients administered a 4 mg warfarin initiation dose between days one and three. On day four, the INR was measured for three to seven days. Subsequently, the initiation dose was adjusted to the therapeutic INR. The INR level was measured every seven days until patients achieved therapeutic INR twice.\u0000Results: A total of 14 patients were included in this study, with a mean age of 62 years. The most common indication for using warfarin was non-valvular atrial fibrillation (85.7%), with a CHA2DS2-VASc score between one and three and a HAS-BLED score ranging from zero to two. The median time to achieve therapeutic INR was 22.2 days, and the predictive value of the day four INR for determining the maintenance dose had an r2= 0.77.\u0000Conclusions: The initiation dose of 4 mg warfarin effectively achieved therapeutic INR within an acceptable time.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Competency analysis of health workers: Interprofessional collaboration practices in a tertiary referral hospital in Surabaya 卫生工作者的能力分析：泗水一家三级转诊医院的跨专业合作实践

IF 0.5

Pharmacy Education Pub Date : 2024-05-12 DOI: 10.46542/pe.2024.243.280285

Hanum Firda Tsabitalya, F. Herawati, Halim Prihayau Jaya, R. Yulia, Setiasih

{"title":"Competency analysis of health workers: Interprofessional collaboration practices in a tertiary referral hospital in Surabaya","authors":"Hanum Firda Tsabitalya, F. Herawati, Halim Prihayau Jaya, R. Yulia, Setiasih","doi":"10.46542/pe.2024.243.280285","DOIUrl":"https://doi.org/10.46542/pe.2024.243.280285","url":null,"abstract":"Background: There is a rising need for high-quality, efficient healthcare. Implementing interprofessional cooperation (IPC) between healthcare professionals is one of the initiatives that has raised the standard of treatment in hospitals. The disparity in competence amongst health professionals is one of several elements that affect the requirements for the successful implementation of cooperation. \u0000Objective: To examine the attitudes, abilities, teamwork, and positive roles implemented by health workers in interprofessional collaboration practices. \u0000Method: Cross-sectional research methodology was used in this observational study. The Chiba Interprofessional Competency Scale (CICS29) instrument, which has 29 verified items, was used to evaluate the proficiency of health workers. The value of five (always) until one (never) was used to distinguish between the various categories. \u0000Result: A very good Cronbach alpha score of 0.921 was used to verify the questionnaire. Exactly 109 health professionals, including 21 physicians, 34 pharmacists, 50 nurses, and four nutritionists, participated in the study as respondents. \u0000Conclusion: Based on the study's findings, it was determined that health professionals, including physicians, pharmacists, nurses, and nutritionists, possess a high level of competence or capacity regarding interprofessional collaboration in hospitals.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140986228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of new training programmes for Thai community pharmacists using the theory of training needs analysis 利用培训需求分析理论为泰国社区药剂师制定新的培训计划

IF 0.5

Pharmacy Education Pub Date : 2024-05-06 DOI: 10.46542/pe.2024.241.290303

S. Watcharadamrongkun, Surangkana Puengrung, Win Winit-Watjana

{"title":"Development of new training programmes for Thai community pharmacists using the theory of training needs analysis","authors":"S. Watcharadamrongkun, Surangkana Puengrung, Win Winit-Watjana","doi":"10.46542/pe.2024.241.290303","DOIUrl":"https://doi.org/10.46542/pe.2024.241.290303","url":null,"abstract":"Background: The study aimed to develop new training programmes for community pharmacists based on the theory of training needs analysis.\u0000Methods: Two phases were conducted. Phase 1 was the pharmacists’ needs analysis using the mixed method with an exploratory sequential design and the Hennessy-Hicks training needs analysis. Eligible pharmacists were requested to rate 44 task items on a 5-point Likert scale for task importance and perceived performance. All data were gathered and analysed using subgroup analysis and exploratory factor analysis for training needs. Phase 2 was the training programme development and verification by a focus group.\u0000Results: A total of 365 pharmacists completed the questionnaire, with a response rate of 28.3%. The 44 primary care tasks were grouped into seven main domains based on their importance. Three tasks with wide training gaps (mean gaps > 2.0), i.e., depression screening, home visits, and family planning, were selected for the programme development. The focus group agreed on the programme’s usefulness, practicality, and ease of implementation.\u0000Conclusion: The training needs of community pharmacists were evaluated, and three training programmes in primary care pharmacy were developed. The impacts of the training programmes merit further study.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141008376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Walking the mile - Fostering diabetes self-management and psychosocial skills among pharmacy students through a hybrid advanced diabetes certificate elective course 行走一英里--通过混合高级糖尿病证书选修课程培养药学专业学生的糖尿病自我管理和社会心理技能

IF 0.5

Pharmacy Education Pub Date : 2024-05-06 DOI: 10.46542/pe.2024.241.277289

Adenike Atanda-Oshikoya, Emanuel George, Lisa Killam-Worrall

{"title":"Walking the mile - Fostering diabetes self-management and psychosocial skills among pharmacy students through a hybrid advanced diabetes certificate elective course","authors":"Adenike Atanda-Oshikoya, Emanuel George, Lisa Killam-Worrall","doi":"10.46542/pe.2024.241.277289","DOIUrl":"https://doi.org/10.46542/pe.2024.241.277289","url":null,"abstract":"Background: Pharmacy school curricula contain required course content in diabetes management. However, patient-care skills like effective communication, lifestyle counselling, and the provision of healthy coping strategies require additional training opportunities that are not typically afforded in the required diabetes curriculum.\u0000Methods: A 2-credit hour elective course was created to provide third-year pharmacy students with first-hand experience in diabetes self-management and the psychosocial aspects of diabetes care. The course includes the certificate training programme \"The Pharmacist and Patient-Centered Diabetes Care\" offered by the American Pharmacists Association (APhA).\u0000Results: 110 pharmacy students completed four-course cohorts. Average capstone assessment scores were 92% for the patient case and 88.3% for hands-on diabetes management skills. 99.1% of students successfully obtained the APhA certificate with an average final assessment score of 85%. Students demonstrated an understanding of the psychosocial and behavioural aspects of diabetes care through simulation and case-based activities.\u0000Conclusion: The course had a positive impact on pharmacy students' proficiency in diabetes care and self-management skills, as evidenced by their performance within the APhA certificate programme. Through simulation activities, students gained firsthand experience and demonstrated an understanding of the psychosocial aspects of diabetes care.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141010821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge and uses of iron supplements to treat anaemia among adolescent girls in Surabaya 泗水少女对治疗贫血的铁补充剂的了解和使用情况

IF 0.5

Pharmacy Education Pub Date : 2024-05-05 DOI: 10.46542/pe.2024.243.256259

Nafiladiniaulia Jihanwasila, Gusti Noorrizka Veronika Achmad, Mareta Rindang Andarsari, Ana Yuda

引用次数: 0