Pharmacy Education最新文献

Antioxidant activity of Bougainvillea spectabilis ethanol extracts as an aryl hydrocarbon inhibitor 作为芳基烃抑制剂的九重葛乙醇提取物的抗氧化活性

IF 0.5

Pharmacy Education Pub Date : 2024-07-07 DOI: 10.46542/pe.2024.243.395400

Ni Nyoman Yuliani, T. Erawati, Jefrin Sambara, Muhamad Satria, Pua Upa

{"title":"Antioxidant activity of Bougainvillea spectabilis ethanol extracts as an aryl hydrocarbon inhibitor","authors":"Ni Nyoman Yuliani, T. Erawati, Jefrin Sambara, Muhamad Satria, Pua Upa","doi":"10.46542/pe.2024.243.395400","DOIUrl":"https://doi.org/10.46542/pe.2024.243.395400","url":null,"abstract":"Background: Antioxidants overcome ageing processes and skin tissue damage caused by free radicals. The flavonoid contents of Bougainvillea spectabilis Willd contain hydroxyl groups attached to the carbon of the aromatic rings which makes them capable of catching free radicals and absorbing UV-A and UV-B. \u0000Objective: This study aimed to investigate the in silico antioxidant activities of various compounds contained in B. spectabilis Willd ethanol extracts compared to control. \u0000Method: The identification was carried out using GCMS methods and Molegro Virtual Docker. The molecular mechanics of scoring functions used in this study were the Rerank score, Root Mean Standard Deviation, and H Bond \u0000Result: p-Trimethylsylyoxylphenyl-(trimethylsilyoxy)trimethylsilyacrilate had a better bond than vitamin C used as the control and is smaller than BHF_401 (A) standard ligand, indicated by rerank scores of -92.6478, -76.0593, and -104.771. \u0000Conclusion: p-Trimethylsilyloxyphenyl-(trimethylsilyloxy)trimethylsilylacrylate had a better and more stable bond (rerank score: -92.6478) than the positive vitamin C control (76.0593).","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Healthcare collaboration intervention: Pre-post study 医疗合作干预：前后研究

IF 0.5

Pharmacy Education Pub Date : 2024-07-07 DOI: 10.46542/pe.2024.243.388394

Zahrotul Hikmah, R. Yulia, Setiasih, Heru Wijono, F. Herawati

{"title":"Healthcare collaboration intervention: Pre-post study","authors":"Zahrotul Hikmah, R. Yulia, Setiasih, Heru Wijono, F. Herawati","doi":"10.46542/pe.2024.243.388394","DOIUrl":"https://doi.org/10.46542/pe.2024.243.388394","url":null,"abstract":"Background: Effective interprofessional collaboration between health professionals is correlated with improving the quality of health services and patient safety, for example, Program Pengendalian Resistensi Antibiotik (PPRA).\u0000Objective: This research aims to determine the effect of educational PPRA on the knowledge and motivation of healthcare professionals in interprofessional collaboration practices.\u0000Methods: The research is quasi-experimental, with one group pre-post using a knowledge questionnaire (questionnaire 1) and a motivation questionnaire (questionnaire 2). The respondents were health professionals at Husada Utama Hospital. This research involved 74 respondents: two doctors, three pharmacists, 41 nurses, five midwives, ten pharmacist assistants, and 13 laboratory assistants.\u0000Results: The analysis of the effect of providing education on health professionals’ knowledge level showed a significant improvement in good categories before and after education, with 55.4% before and 73% after (Sig. = 0.025, p < 0.05). The analysis of the level of motivation showed that moderate categories grew insignificantly before and after education, with 39.19% before and 47.30% after (Sig = 0.599, p > 0.05).\u0000Conclusion: This research concluded that PPRA education's effect on health workers' knowledge and motivation in interprofessional collaboration at Husada Utama Hospital has increased knowledge and motivation. ","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and a validation study of comprehensive prescription writing rubrics for medical students 医科学生综合处方书写评分标准的开发与验证研究

IF 0.5

Pharmacy Education Pub Date : 2024-07-07 DOI: 10.46542/pe.2024.241.403417

Anupong Kantiwong, Sethapong Lertsakulbunlue

{"title":"Development and a validation study of comprehensive prescription writing rubrics for medical students","authors":"Anupong Kantiwong, Sethapong Lertsakulbunlue","doi":"10.46542/pe.2024.241.403417","DOIUrl":"https://doi.org/10.46542/pe.2024.241.403417","url":null,"abstract":"Background: Prescribing is a complex task for physicians, with many global reports of errors. This study evaluates a comprehensive rubric for medical student prescribing skills regarding validity and reliability.\u0000Methods: Twenty-one third-year medical students participated in three separate prescribing exams. Two pharmacology professors rated the students' prescriptions using a rubric covering ten criteria. Messick validity framework was utilised to enhance the study’s validity. Generalisability theory (G-theory) helped determine the source of variance and the optimal number of raters and test occasions.\u0000Results: Content validity was ensured by three experts and alignment with the Thai Medical Council criterion. The Inter-rater and test-retest reliability were acceptable. The rubric had a Cronbach's alpha 0.70 with item-test correlation, all above 0.40. G-theory indicated that 54.93% of the total variance was due to performance and 27.57% to the interaction between performance and occasions, with a minimal residual variance of 4.28%. To reach an acceptable Phi-coefficient (≥0.70), three occasions with one rater (Phi-coefficient=0.76) or two occasions with two raters (Phi-coefficient=0.72) are needed. Conversely, the Phi-coefficient was low on a single occasion.\u0000Conclusion: The study introduces a comprehensive rubric and description of a prescription writing programme to minimise potential prescribing errors in pre-clinical years. Furthermore, more assessment opportunities enhance knowledge retention and assessment reliability.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Listener, member, and advisor perspectives regarding a pharmacy podcast student organisation 听众、成员和顾问对药学播客学生组织的看法

IF 0.5

Pharmacy Education Pub Date : 2024-07-07 DOI: 10.46542/pe.2024.241.394402

Joshua Wollen, Alexa Zhao, Sama Rahimi, Sourab Ganna, Kimberly Nguyen

{"title":"Listener, member, and advisor perspectives regarding a pharmacy podcast student organisation","authors":"Joshua Wollen, Alexa Zhao, Sama Rahimi, Sourab Ganna, Kimberly Nguyen","doi":"10.46542/pe.2024.241.394402","DOIUrl":"https://doi.org/10.46542/pe.2024.241.394402","url":null,"abstract":"Background: This work describes the structure and function of a pharmacy student-led Podcast Student Organisation (PSO) through the perspectives of the organisation’s members, listeners, and advisors. It aims to provide a blueprint for other colleges of pharmacy to replicate and develop their own programmes and share the experiences of those involved with the PSO.\u0000Methods: Perspectives from the advisors were gathered via statements. The listener and member perspectives were collected via a survey. Data were collected to share the listener and PSO member experience regarding the PSO.\u0000Results: Based on the post-surveys meeting inclusion criteria (n = 32), most listeners showed statistically significant improvement in attitudes towards the topic of the episode (p = 0.027) and their college of pharmacy (p = 0.017). The podcast team showed statistical improvement in attitudes towards their college of pharmacy (p = 0.020) and their Doctor of Pharmacy curriculum (p = 0.046). Satisfaction responses were overwhelmingly positive after listening to the episodes.\u0000Conclusion: The PSO may help improve attitudes towards some topics and promote positive feelings regarding students’ college. This description of the PSO and lessons learned may serve as a blueprint for colleges of pharmacy considering implementation and encourage others to adopt a PSO.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141671298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of pharmacy students’ anxiety towards graduation research during their undergraduate degree in Saudi Arabia 沙特阿拉伯药学专业学生对本科毕业研究焦虑的评估

IF 0.5

Pharmacy Education Pub Date : 2024-07-06 DOI: 10.46542/pe.2024.241.382393

S. Khayyat, Bayan Ainousah

{"title":"Assessment of pharmacy students’ anxiety towards graduation research during their undergraduate degree in Saudi Arabia","authors":"S. Khayyat, Bayan Ainousah","doi":"10.46542/pe.2024.241.382393","DOIUrl":"https://doi.org/10.46542/pe.2024.241.382393","url":null,"abstract":"Background: The benefits of undergraduate research are far-reaching; however, acquiring research experience can be challenging. Recently, students’ mental health has garnered attention as it can impact academic outcomes. Therefore, this study aimed to assess anxiety levels related to research among undergraduate pharmacy students and identify contributing factors.\u0000Methods: A cross-sectional online survey was administered to pharmacy students from various Saudi universities between January 9, and February 28, 2023. The eligible participants were sixth- or fifth-year students who had completed at least 50% of their research project.\u0000Results: Of the 273 respondents, most had a B grade point average (51.6%) and lacked prior research experience (86.8%). The study revealed that 68.1% of students experienced anxiety about their research. Among the 20 factors examined, five were identified as significantly and strongly associated with students’ anxiety: data collection methods, challenges in writing research reports, time constraints for completing research, academic workload, and the availability of supportive individuals for discussing problems. However, anxious students also reported higher positive views towards their supervisor’s feedback on the research report. \u0000Conclusion: The findings highlight a considerable prevalence of anxiety among undergraduate pharmacy students during their research endeavours. Addressing these challenges is crucial for fostering a supportive academic environment conducive to students’ research and educational success.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141672951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stakeholder perspectives on the need for professional education and competence in pharmacovigilance in Zambia: A cross-sectional survey 利益相关者对赞比亚药物警戒专业教育和能力需求的看法：横断面调查

IF 0.5

Pharmacy Education Pub Date : 2024-07-06 DOI: 10.46542/pe.2024.241.364381

A. Kalungia, M. Banda, M. Mukosha, Michael Chigunta, Steward Mudenda, S. Banda, J. Sichone, Audrey Hamachila, Brian Godman

{"title":"Stakeholder perspectives on the need for professional education and competence in pharmacovigilance in Zambia: A cross-sectional survey","authors":"A. Kalungia, M. Banda, M. Mukosha, Michael Chigunta, Steward Mudenda, S. Banda, J. Sichone, Audrey Hamachila, Brian Godman","doi":"10.46542/pe.2024.241.364381","DOIUrl":"https://doi.org/10.46542/pe.2024.241.364381","url":null,"abstract":"Background: Knowledge and skills in pharmacovigilance (PV) are required to mitigate adverse events associated with medicine use which are among the leading causes of morbidity, mortality, and healthcare costs. This study explored the local perspectives and needs for PV education in Zambia.\u0000Methods: A mixed-methods study utilising a descriptive cross-sectional survey with an embedded desk review was conducted from November 2021 to December 2022 in Zambia. The quantitative survey used a self-administered questionnaire distributed to 150 participants drawn from key stakeholder groups identified. Qualitative information was extracted from the respective university websites for the desk review.\u0000Results: Out of 150 targeted participants, 144 (96%) responded to the survey. The majority (92.4%) affirmed the need for formal PV education programmes locally. Most (95.8%) perceived that training professionals in PV would add value to strengthening the health system. Furthermore, 45.1% preferred a postgraduate diploma and a master’s degree in PV. About half (48.6%) preferred an interprofessional training approach. Only 6/1207 (0.5%) of the universities in Sub-Saharan Africa offered PV education programmes.\u0000Conclusion: This study underscored the pertinent need for formal PV education programmes and identified the type of education, expected competencies, and suggested educational strategies to guide curriculum development. These findings serve as a starting point for developing programmes to consolidate PV practice in Zambia and beyond.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141672579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of the relationship between Doxorubicin and Doxorubicinol, CBR1 polymorphism, and cardiotoxicity 多柔比星和多柔比星醇、CBR1 多态性与心脏毒性之间关系的综述

IF 0.5

Pharmacy Education Pub Date : 2024-06-14 DOI: 10.46542/pe.2024.246.105115

Talia Putri Rahmani, Y. Harahap, D. Purwanto

{"title":"A review of the relationship between Doxorubicin and Doxorubicinol, CBR1 polymorphism, and cardiotoxicity","authors":"Talia Putri Rahmani, Y. Harahap, D. Purwanto","doi":"10.46542/pe.2024.246.105115","DOIUrl":"https://doi.org/10.46542/pe.2024.246.105115","url":null,"abstract":"Background: Doxorubicin is a chemotherapy drug given to breast cancer patients. However, its administration is limited by its cardiotoxicity. The CBR1 enzyme in the liver catalyses doxorubicin to doxorubicinol, which also contributes to its cardiotoxicity. The polymorphism of the CBR1 enzyme affects doxorubicin and doxorubicinol levels in the body.\u0000Objective: To review the effect of CBR1 polymorphisms on the levels of doxorubicin and doxorubicinol after administration of doxorubicin.\u0000Methods: Relevant studies from selected databases were examined; Three main studies with 20 support studies were reviewed.\u0000Results: The recommended methods were the analysis of doxorubicin and doxorubicinol levels using the Dried Blood Spot biosampling technique, which uses the ultra-high-performance liquid chromatography-tandem mass spectrometry (LCMS/MS), and the evaluation of the genetic profile of CBR1 using Polymerase Chain Reaction.\u0000Conclusion: Four CBR1 genetic polymorphisms have been shown to reduce doxorubicinol levels in the body, which is associated with decreased CBR1 activity and expression. Thus, the conversion of doxorubicin to doxorubicinol is reduced. Therefore, individuals who experience CBR1 polymorphisms have a lower risk of cardiotoxicity after the administration of doxorubicin.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141341623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the antioxidant properties of Pilea trinivera (Roxb.) Wight) by in vitro and in vivo studies 通过体外和体内研究评估 Pilea trinivera (Roxb.) Wight 的抗氧化特性

IF 0.5

Pharmacy Education Pub Date : 2024-06-14 DOI: 10.46542/pe.2024.246.144148

Y. Sumiyati, Reise Manninda, Alessandro Volta Gunady, Afifah Putri Nadiah, Winana Kartika Dewi

{"title":"Assessing the antioxidant properties of Pilea trinivera (Roxb.) Wight) by in vitro and in vivo studies","authors":"Y. Sumiyati, Reise Manninda, Alessandro Volta Gunady, Afifah Putri Nadiah, Winana Kartika Dewi","doi":"10.46542/pe.2024.246.144148","DOIUrl":"https://doi.org/10.46542/pe.2024.246.144148","url":null,"abstract":"Background: Pohpohan leaves (Pilea trinivera (Roxb.) Wight), commonly consumed as fresh vegetables, contain flavonoids useful as antioxidants. Literature studies showed the content of quercetin, kaempferol, myricetin, luteolin, and apigenin.\u0000Objective: The research aimed to determine the antioxidant activity of 70% ethanolic extract of Pohpohan leaves in Wistar rats induced by heat stress with the parameters malondialdehyde (MDA) and superoxide dismutase (SOD).\u0000Method: The pilot study found the extract's total flavonoid, phenolic content, and IC50, respectively, 1.48%, 1.64%, and 79.65ppm. The sample consisted of 30 male Wistar rats that met the criteria and were divided into six groups. MDA levels were determined using the TBARs method, while SOD activity was measured using the spectrophotometric method. Data analysis was done using the Mann-Whitney test.\u0000Result: MDA levels (nmol/mL) for normal control, negative control, positive control, doses I, II and III group, respectively, were 2.581; 12.978;0.830; 8.597; 6.041; 2.291 whereas the SOD activity (U/mL) of each group was 161.55; 101.54; 267.70; 184.62; 207.69; 240. There were no significant differences in MDA and SOD levels between the positive control group and dose III.\u0000Conclusion: The results showed the antioxidant activity of the ethanol extract of Pilea trinervia (Roxb.) Wight).","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141342055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antidiabetic and antioxidant activity of Clitoria ternatea flower extracts and fractions on blood glucose and MDA in rats induced by alloxan 燕麦花提取物和馏分对阿脲诱导的大鼠血糖和 MDA 的抗糖尿病和抗氧化活性

IF 0.5

Pharmacy Education Pub Date : 2024-06-14 DOI: 10.46542/pe.2024.246.2127

Widyaningrum Utami, Yunanto Dwi Laksono, Syakira Nilam Farhana Setiawibowo, Endang Sri Sunarsih, Fitri Wulandari, Evieta Rohana

{"title":"Antidiabetic and antioxidant activity of Clitoria ternatea flower extracts and fractions on blood glucose and MDA in rats induced by alloxan","authors":"Widyaningrum Utami, Yunanto Dwi Laksono, Syakira Nilam Farhana Setiawibowo, Endang Sri Sunarsih, Fitri Wulandari, Evieta Rohana","doi":"10.46542/pe.2024.246.2127","DOIUrl":"https://doi.org/10.46542/pe.2024.246.2127","url":null,"abstract":"Background: Clitoria ternatea, rich in anthocyanins with antioxidant properties, can help prevent oxidative stress and reduce complications associated with diabetes mellitus (DM).\u0000Objective: To investigate the antidiabetic and antioxidant properties of the ethanol extract and ethyl acetate fraction of Clitoria ternatea in rats induced by Alloxan.\u0000Method: Ethanol extract from Clitoria ternatea was fractionated with ethyl acetate and then screened for phytochemicals using TLC. Antidiabetic and antioxidant activities were evaluated on alloxan-induced hyperglycemic rats at 150 mg/kgBW and 300 mg/kgBW, respectively.\u0000Result: The Clitoria ternatea flower's ethanol extract and ethyl acetate fraction had a flavonoid content of 68.003±0.366 mg QE/g and 78.767±0.262 mg QE/g, respectively. The ethyl acetate fraction, administered at 300 mg/kg BW, showed a 45.5986 mg/dl reduction in blood glucose levels, not significantly different from the positive control (acarbose (p = 0.14). The ethyl acetate fraction showed a significant reduction of 76.5% in MDA levels, similar to quercetin as a positive control (p = 0.275).\u0000Conclusion: Clitoria ternatea showed antidiabetic and antioxidant properties in alloxan-induced rats.\u0000 ","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141341229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Purple sweet potato antioxidants for oxidative stress caused by intense physical exercise 紫甘薯抗氧化剂可应对剧烈运动造成的氧化应激

IF 0.5

Pharmacy Education Pub Date : 2024-06-14 DOI: 10.46542/pe.2024.246.128133

Laurens Frestasya, R. C. Pangsibidang

{"title":"Purple sweet potato antioxidants for oxidative stress caused by intense physical exercise","authors":"Laurens Frestasya, R. C. Pangsibidang","doi":"10.46542/pe.2024.246.128133","DOIUrl":"https://doi.org/10.46542/pe.2024.246.128133","url":null,"abstract":"Background: Intense exercise increases ROS and reactive nitrogen species, leading to oxidative stress and potential health issues. Balancing free radical production and antioxidant defence is crucial. Endogenous antioxidants help neutralise ROS, but additional supplementation is required to prevent cell damage.\u0000Objective: This literature review explores the potential of purple sweet potato (Ipomoea batatas L.) as an antioxidant source to counteract exercise-induced oxidative stress.\u0000Method: Scientific articles from various platforms were collected using keywords such as \"Physical exercise,\" \"Oxidative stress,\" \"Purple sweet potato,\" and \"Antioxidant”.\u0000Result: Purple sweet potato, rich in anthocyanins and vitamin C, exhibits potent free radical scavenging properties. Consumption of purple sweet potato enhances superoxide dismutase (SOD) levels, reduces lipid peroxidation (MDA), inhibits the NF-kB signalling pathway, and prevents increased heat shock protein 72 (HSP72) expression. These findings suggest that purple sweet potato consumption promotes cellular health and mitigates oxidative stress caused by intense physical exercise.\u0000Conclusion: In conclusion, incorporating purple sweet potato into the diet shows promise in countering exercise-induced oxidative stress, promoting overall well-being, and preventing chronic diseases. Further research is needed to fully understand the mechanisms and optimal dosage for combating oxidative stress during rigorous physical training.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141339642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0