{"title":"Highlighting the pivotal role of the pharmacist in influencing health behaviours during emergency crisis: A lesson from the COVID-19 pandemic","authors":"Katia Iskandar, Souheil Hallit, Chadia Haddad, Irfan Mohammed, Feten Fekih-Romdhane, Rawshan Jabeen, Michelle Cherfane, Elise Makhoul, Marwan Akel, Sarah El Khatib, Rohul Amin, Anna Brytek-Matera, Nebojša Pavlovic, Rula Darwish, Mainul Haque, Jayaseelan Murugaiyan, Shadrach Chinecherem Eze, Randa Choueiry, Kenneth Egwu, Nagham Khanafer, Magdalena Mróz, Vijaya Pavani Molli, Tamires Furtado Rockenbach, Joanna Sitarska, Ana Tomas, Pascale Salameh","doi":"10.46542/pe.2023.231.676692","DOIUrl":"https://doi.org/10.46542/pe.2023.231.676692","url":null,"abstract":"Background: The contribution of the pharmacist in influencing health behaviours and raising awareness of the impact of self-medication (SM) is valuable. During the COVID-19 pandemic, SM was triggered by multiple factors driven by the fear of becoming infected. This study aimed to identify the determinants of SM during the outbreak, with a focus on the role of social media, and to determine areas where the active contribution of the pharmacist needs strengthening. Methods: A pilot cross-sectional study using snowball sampling was conducted in thirteen countries. Results: A total of 2369 participants with a mean age of 30.62±11.57 years were enrolled in the study. The determinants of SM were 1) sociodemographic characteristics, including developing countries (ORa= 0.670; 95%CI [0.49, 0.91]); 2) communication channels, where Facebook was the most used social media platform (ORa=1.624; 95%CI [1.29, 2.05]); and 3) content and sources of unverified information, i.e. television interviews (ORa=1.357; 95%CI [1.03, 1.78]) and videos with someone confirming the effectiveness of medication used (ORa=1.353; 95%CI [1.06, 1.73]). The perceived risk severity was associated with elderly polypharmacy (ORa= 2.468; 95%CI [1.87, 3.26]). Conclusion: The pharmacist should collaboratively and actively contribute to the design and implementation of health promotion programmes and convert to positive the influence of social media.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"37 19","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135038686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and attitudes of pharmacy students towards artificial intelligence and the ChatGPT","authors":"Makiko Iwasawa, Masahiro Kobayashi, Katsuya Otori","doi":"10.46542/pe.2023.231.665675","DOIUrl":"https://doi.org/10.46542/pe.2023.231.665675","url":null,"abstract":"Background: This study examined pharmacy students' knowledge and attitudes to artificial intelligence (AI) and ChatGPT. Methods: A survey was conducted with 258 fourth-year pharmacy students at Kitasato University, Japan, assessing their AI knowledge, ChatGPT impressions, and literacy regarding its appropriate use. Data were analysed descriptively, and participants were divided into two groups based on ChatGPT awareness for further analysis. Results: A total of 113 students (43.7%) participated, with 19.5% having prior ChatGPT experience, 4.4% were unaware, and 42.5% could describe it. General AI terms like \"machine learning\" were more familiar (83.2%) than specific ones like \"natural language processing\" (2.6%). Positive impressions of ChatGPT included 65.5% finding it efficient and 50.4% mentioning enhanced comprehension. However, only 3.5% correctly identified all inappropriate purposes, and 24.8% selected all precautions for its use. The 48 participants (42.5%) who described ChatGPT and had higher AI knowledge showed more correct answers than the other group (65 participants, 57.5%). Conclusion: Students with AI knowledge and the ability to describe ChatGPT demonstrated a better understanding of its appropriate usage. Educating students on AI fundamentals helps them utilise AI tools like ChatGPT effectively. This study offers valuable insights on ChatGPT among pharmacy students, with implications for responsible AI usage and education.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"20 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136316627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring learning analytics and motivated strategies for learning questionnaire (MSLQ) to understand pharmacy students’ learning profiles, motivation and strategies post-COVID","authors":"Chee-Yan Choo, Hui Poh Goh, Chiau Ming Long","doi":"10.46542/pe.2023.231.656664","DOIUrl":"https://doi.org/10.46542/pe.2023.231.656664","url":null,"abstract":"Background: First-year pharmacy students experienced on-site education after three years of studying online in isolation. Objectives: This study aimed to analyse newly enrolled first-year pharmacy students’ learning profiles using learning analytics from YouTube, and further understand their motivation and learning strategy during the transition period. Method: Learning Analytics (LA) were retrieved from YouTube analytics on instructor-generated videos. Students’ motivation and learning strategies were acquired using the Motivated Strategies for Learning Questionnaire (MSLQ) with a seven-point Likert score distributed online using Google Forms. Data were analysed using SPSS, and interview sessions were conducted with some of the students. Results: The LA showed most students referred to the instructor-generated video during study week. Students avoided the tutorial video with a view ratio lower than 1.0. This result correlated with the lower metacognitive mean compared to the cognitive level in the MSLQ analysis. Dependant on extrinsic components has increased their anxiety level. The peer learning scored higher than the help-seeking and was confirmed through interviews. Conclusion: This study offers insights into students learning motivation and strategies. Well-designed instructional learning activities may help in improving their problem-solving skills to boost their motivation. The teacher-student relationship may need more effort to build.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"32 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134906928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The design of a “1-minute break” to help with students’ attention during lectures in a Pharm.D. programme","authors":"Ahmad Hanif, Marina Galvez-Peralta","doi":"10.46542/pe.2023.231.648655","DOIUrl":"https://doi.org/10.46542/pe.2023.231.648655","url":null,"abstract":"Background: The “1-minute break” is a novel educational approach that introduces intentional breaks through trivia questions to address students’ challenges with paying attention during class time. Methods: After it was initiated and optimised, the “1-minute break” has been offered to students in different cohorts within the Pharm.D. pre-APPE programme for the past five years. Feedback on the utility of this innovative approach and its optimisation was gathered over the five years. Students also shared their perception of the impact of the “1-minute break” on their attention during classes using a survey with open-ended questions. Results: The “1-minute break” was highly accepted by all student cohorts. Students strongly favoured implementing this technique across the curriculum. Qualitative analysis of student feedback revealed that the “1-minute- break” helped them stay focused or regain attention in class. Student feedback provided similar comments before, during, and after the COVID-19 pandemic, reflecting that this technique can be implemented independently of the online and in-person teaching formats. Conclusion: The “1-minute break” technique, which uses intentional breaks by incorporating trivia questions during lectures, seems to help students stay focused or regain their attention during classes. This approach is easily implemented and apparently independent of the content taught.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136178144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Honey Dzikri Marhaeny, Alma Nuril Aliyah, Andang Miatmoko, Junaidi Khotib
{"title":"Investigating the anti-allergic activity of Phyllanthus niruri via MALT1 protease inhibition: An in silico approach","authors":"Honey Dzikri Marhaeny, Alma Nuril Aliyah, Andang Miatmoko, Junaidi Khotib","doi":"10.46542/pe.2023.234.196202","DOIUrl":"https://doi.org/10.46542/pe.2023.234.196202","url":null,"abstract":"Background: Allergic inflammation is a condition caused by complex interactions between several inflammatory cells in the body. Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is a cysteine protease that bridges innate and adaptive immune responses in allergic inflammation. MALT1 protease inhibition is a potential strategy for controlling IgE-mediated allergic disease. P. niruri is a medicinal plant with anti-allergic properties. Objective: This study aimed to evaluate the anti-allergic activity of P. niruri secondary metabolites against MALT1 protease through in silico approach. Method: Physicochemical properties and drug-likeness evaluation were determined using SwissADME. The toxicity properties prediction was analysed using pkCSM. AutoDock Vina was used to evaluate the best binding energy of the compounds against the receptor (PDB ID: 3V4O and 4I1R). Visualisation was obtained using Biovia discovery studio visualiser. Result: Docking analysis showed that ten of 21 compounds have lower binding affinity than the native ligand and reference drugs at the 3V4O receptor. At the 4I1R receptor, only three compounds have a lower binding affinity than its native ligand, but only one compound has a lower binding affinity than all reference drugs. Conclusion: Several P. niruri secondary metabolites were potentially predicted to be developed as MALT1 protease inhibitory agents.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136295559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ika Puspita Dewi, Fifteen Aprila Fajrin, Nadia Kholidatul Yumna, Hesti Nur Rahmawati, Fransiska Maria Christanty, Diana Holidah
{"title":"Protective effects of Piper crocatum ethanol extract on Gentamicin-induced nephrotoxicity in rats","authors":"Ika Puspita Dewi, Fifteen Aprila Fajrin, Nadia Kholidatul Yumna, Hesti Nur Rahmawati, Fransiska Maria Christanty, Diana Holidah","doi":"10.46542/pe.2023.234.3236","DOIUrl":"https://doi.org/10.46542/pe.2023.234.3236","url":null,"abstract":"Background: The kidney is one of the main target organs of toxic substances, including drugs. Gentamicin-induced nephrotoxicity is thought to be caused by the formation of oxidative stress and can be prevented by antioxidants. Piper crocatum has potent antioxidant activity. Objective: This study aims to determine the nephroprotective activity of Piper crocatum. Method: The study used Wistar rats in five groups (normal, negative, and ethanol extract of Piper crocatum with doses of 250, 500, and 750 mg/kg BW). The nephrotoxicity was induced by gentamicin for eight days. On the ninth day, the kidney function parameters (blood, urea, nitrogen, creatinine and uric acid) and malondialdehyde levels were measured, and kidney histology analysis was performed. Results: The results demonstrated that the extracts show lower kidney function parameters and malondialdehyde levels than the negative control. Conclusion: Piper crocatum is a potential nephroprotective agent.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136295564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment success and related factors of drug-susceptible and drug-resistant tuberculosis patients in Aceh referral hospital","authors":"Novi Maulina, None Zinatul Hayati, None Zulkarnain, None Kartini Hasballah, None Ika Waraztuty","doi":"10.46542/pe.2023.234.289293","DOIUrl":"https://doi.org/10.46542/pe.2023.234.289293","url":null,"abstract":"Background: Tuberculosis (TB) remains one of the top ten causes of mortality worldwide. It is caused by a single infectious agent, Mycobacterium tuberculosis. Indonesia has the second highest cases globally and has a high burden of rifampicin-resistant (RR-TB). Xpert MTB/RIF has been used as a frontline test to detect RR-TB to improve treatment efficacy. Objective: This study aims to summarise the bacteriologic conversion rate as the patient’s cured hallmark and related factors among adults confirmed to have pulmonary tuberculosis in a referral hospital in Aceh Province. Method: The authors assessed 1,244 bacteriologic test results of sputum samples from TB presumptive patients from January 1st to December 31st 2018, in the Clinical Microbiology Laboratory and evaluated bacteriologic conversion. Result: There were 361 bacteriologic-confirmed TB diagnoses, where 43 (11.9%) were RR-TB. Most TB patients (26.3%) were in close contact with active TB patients. Conclusion: The study showed TB patients' low follow-up rate and bacteriologic conversion. The high prevalence of TB among close contacts suggests a need for constant surveillance of this high-risk group to end the TB epidemic. Male, young adult, and Aceh Besar residents have observed factors in sputum conversion results.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"807-809 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136295567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prehatin Trirahayu Ningrum, Yulis Ekaningrum, Rahayu Sri Pujiati
{"title":"Soursop leaf extract (Annona muricata L) as a biochemical pesticide against fruit flies (Bactrocera sp)","authors":"Prehatin Trirahayu Ningrum, Yulis Ekaningrum, Rahayu Sri Pujiati","doi":"10.46542/pe.2023.234.99104","DOIUrl":"https://doi.org/10.46542/pe.2023.234.99104","url":null,"abstract":"Background: The citrus cultivation industry is commonly operated by the government, private sector, or individual owners from small, medium, to large scales. The fruit flies (Bactrocera sp) insect was reported to attack citrus crops in almost every region in Indonesia. Objective: To determine the effectiveness of soursop leaf extract (Annona muricata L) as a plant-derived insecticide against fruit flies. Methods: This study used true experimental with Posttest Only Control Design to analyse the difference in the average mortality of fruit flies for 24 hours. Results: The data generated through the Kruskal Wallis test showed that at a concentration of five per cent and 10% the effect of the mortality in fruit flies equals p > 0.939. However, at a concentration of 15%, the number decreased to p < 0.001. This finding showed that the compound has evolved its function to antifeedant only or as a secondary metabolite that does not result in immediate death but rather gives discomfort to insects. Conclusion: The use of an antifeedant compound as a biopesticide can inhibit fruit flies’ attack on citrus crops.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136295702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the pharmacist role and challenges during COVID-19 pandemic in the public healthcare setting: A qualitative study","authors":"Asri Putri Pratiwi, Wahyu Utami, Umi Athiyah, Abdul Rahem, Anila Impian Sukorini, Andi Hermansyah","doi":"10.46542/pe.2023.234.247250","DOIUrl":"https://doi.org/10.46542/pe.2023.234.247250","url":null,"abstract":"Background: Pharmacists working in the Public Health Center (PHC) setting are at the frontline response and often have to adapt to the COVID-19 crisis. However, there is a deficit of studies examining their roles and challenges regarding providing pharmaceutical care and how they adapt to the COVID-19 situation in Indonesia. Objective: This study aims to explore the views and experiences of pharmacists in the PHC during the COVID-19 pandemic. Methods: Four Focus Group Discussions (FGDs) involving 40 PHC pharmacists working in Surabaya were conducted in May 2021. The FGDs were audio recorded, transcribed verbatim and subsequently analysed for any emerging theme. Results: Most participants viewed that the restriction of face-to-face interaction hampered the provision of pharmaceutical care in the PHC. Protective equipment and partition screens during patient visits have challenged pharmacists to communicate effectively. Services such as direct one-on-one drug information and patient counselling were still provided, often facilitated with written aids, but for a limited time, providing opportunities for pharmacists to deliver messages through WhatsApp and telephone. Conclusion: The COVID-19 pandemic significantly impacted pharmaceutical service delivery in PHC. However, it has preserved the important role of pharmacists to ensure safe and quality services, particularly with the presence of the COVID-19 vaccination programme.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136296369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An analysis of the Michaelis-Menten pharmacokinetics of phenytoin in epileptic Indonesian adults","authors":"None Sumarno, None Kurnia Kusumastuti, None Junaidi Khotib","doi":"10.46542/pe.2023.234.311315","DOIUrl":"https://doi.org/10.46542/pe.2023.234.311315","url":null,"abstract":"Background: Phenytoin metabolism has been shown to vary in different ethnic groups. Therefore, the authors studied phenytoin pharmacokinetics in Indonesian adult patients with epilepsy. Objective: The purpose of this study was to determine and analyse the pharmacokinetic parameters of Michaelis Menten Vmax (maximum velocity) and Km (the Michaelis constant) of phenytoin in adult epileptic patients. Method: Twelve adult epileptic patients were chosen on the basis that they had two reliable steady-state phenytoin serum levels at two different daily doses and they required an additional adjustment of phenytoin dosage monotherapy. Result: The Vmax and Km values for adult epileptic patients respectively, ranged from 3.78 to 9.65 mg/kg/day and from 0.71 to 5.58 mg/L and there was no correlation with age and weight (p > 0.05). The Vmax and Km values have shown individual variability. Conclusion: The optimal adjustment of phenytoin dose individually in adult epileptic patients based on Vmax and Km parameters needs to be done to get the desired steady-state level according to the clinical response.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136352587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}