Natural Product Research最新文献_第2页

Extraction optimisation and compositional characterisation of total flavonoids from the Chinese herb tulip: a natural source of antioxidants and anti-inflammatory agents. 抗氧化剂和抗炎剂的天然来源——郁金香总黄酮的提取优化和成分表征。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-15 DOI: 10.1080/14786419.2023.2281000

Jiafeng Ye, Jiamin Cao, Xian Chen, Jingjing Ma, Yangchen Li, Xia Gao, Yurui Zhang, Chunli Wang

引用次数: 0

Ultrasonic-Microwave extraction of glucoside alkaloids from potato peel residue and its antibacterial activity. 超声波-微波法从马铃薯皮渣中提取葡萄糖苷生物碱及其抗菌活性。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-10 DOI: 10.1080/14786419.2023.2278755

Zhongliang Guan, Qingmin Chen, Ye Xu, Cong Han, Min Wang, Tao Zhao, Handong Zhao, Maorun Fu

{"title":"Ultrasonic-Microwave extraction of glucoside alkaloids from potato peel residue and its antibacterial activity.","authors":"Zhongliang Guan, Qingmin Chen, Ye Xu, Cong Han, Min Wang, Tao Zhao, Handong Zhao, Maorun Fu","doi":"10.1080/14786419.2023.2278755","DOIUrl":"10.1080/14786419.2023.2278755","url":null,"abstract":"A new extraction and bacteriostatic ability of glucoside alkaloids in potato peel. To make better use of glucoside alkaloids, this experiment adopted ultrasonic microwave combined extraction of glucoside alkaloids from potato peel; then, the extracts of potato peel were subjected to bacteriostatic assays. The optimum experimental condition of response surface method was that the solid-liquid ratio was 1:18.00 g/mL, the ultrasonic power 505.00 W, the microwave time was 6.10 min and the ultrasonic time was 10.70 min. Under those conditions, the extraction amount of glucoside alkaloids was 292.91 mg/kg, which increased by about 28% compared with the QUEChERS method. The antibacterial activity of the obtained glucoside alkaloids was tested using five kinds of strains, and the results showed that Penicillium and Colletotrichum gloeosporioides were more sensitive. The results indicated that Ultrasonic-Microwave combined extraction was more efficient and convenient than that of QuEChERS method for glucoside alkaloids and related antibacterial compounds from potato peel.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4141-4145"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72210126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Botanical description, phytochemical constituents, ethnobotany, traditional medicinal use, and pharmacological activities of Stachys lavandulifolia Vahl. Stachys lavandulifolia Vahl.的植物学描述、植物化学成分、人种植物学、传统药用和药理活性。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2024-01-08 DOI: 10.1080/14786419.2023.2301004

Dara Dastan, Christopher Dobie, Reza Zadali, Mouhamad Hassan Pourrashid, Danielle Skropeta, Mansour Miran

{"title":"Botanical description, phytochemical constituents, ethnobotany, traditional medicinal use, and pharmacological activities of Stachys lavandulifolia Vahl.","authors":"Dara Dastan, Christopher Dobie, Reza Zadali, Mouhamad Hassan Pourrashid, Danielle Skropeta, Mansour Miran","doi":"10.1080/14786419.2023.2301004","DOIUrl":"10.1080/14786419.2023.2301004","url":null,"abstract":"Stachys lavandulifolia Vahl known as \"mountain tea\", is a perennial flowering plant belonging to the Lamiaceae family and is widespread in Iran, Armenia, Azerbaijan, Iraq, Turkey and Turkmenistan. S. lavandulifolia is widely used in traditional medicine for its analgesic, anti-inflammatory and anxiolytic properties. This plant has different chemical compounds classes including terpenoids, iridoids, flavonoids and phenylethanoids that have been isolated from the aerial parts of it. This review covers the plant botany, traditional medicinal uses and chemical composition of S. lavandulifolia, along with its biological and pharmacological activities including clinical trial data. The information of this review article was obtained from different scientific databases such as Google scholar, Science Direct, Hindawi, SID, Scopus, PubMed, and ACS as well as traditional Persian books. Pharmacological and clinical studies, especially Anxiolytic activity and anti-inflammatory on the plant are relatively low, so these studies are suggested in the future. Also, phytochemical investigation on root of the plant is necessary.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4479-4493"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leishmanial activity of Brazilian brown propolis and its diterpenes. 巴西棕蜂胶及其二萜的利什曼原虫活性。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-02 DOI: 10.1080/14786419.2023.2277351

Larissa Costa Oliveira, Victor Pena Ribeiro, Mario Ferreira Conceição Santos, Nicoli Dias Oliveira, Matheus Henrique Marques Zago, Iaciara Luana de Xavier Albernaz, Rodrigo Cassio Sola Veneziani, Jairo Kenupp Bastos, Lizandra Guidi Magalhães, Sérgio Ricardo Ambrósio

{"title":"Leishmanial activity of Brazilian brown propolis and its diterpenes.","authors":"Larissa Costa Oliveira, Victor Pena Ribeiro, Mario Ferreira Conceição Santos, Nicoli Dias Oliveira, Matheus Henrique Marques Zago, Iaciara Luana de Xavier Albernaz, Rodrigo Cassio Sola Veneziani, Jairo Kenupp Bastos, Lizandra Guidi Magalhães, Sérgio Ricardo Ambrósio","doi":"10.1080/14786419.2023.2277351","DOIUrl":"10.1080/14786419.2023.2277351","url":null,"abstract":"Propolis is a natural product widely used in folk medicine. Among its various applications, its antiparasitic properties stand out. Due to its great biodiversity, Brazil is a major producer of several types of propolis. This study proposes to evaluate the leishmanicidal properties of the hydroalcoholic extract of propolis collected in the southern region of Brazil (Brown propolis - HEBP) and its main isolated compounds: abietic acid (1), 13-epi-cupressic acid (2), 13-epi-torulosol (3), dehydroabietic acid (4), cis-communic acid (5) and ent-agatic acid (6). In general, the diterpenes did not show activity against the promastigotes of Leishmania (Leishmania) amazonensis at the evaluated concentrations. However, the HEBP was very active with an inhibition concentration of 50% at 8.32 µg/mL. Moreover, transmission electron microscopy (TEM) and scanning electron microscopy (SEM) assays showed morphological and structural alterations in promastigote forms of L. (L.) amazonensis when incubated with HEBP.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4302-4306"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71425218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential of insect endogenous cellulases for lignocellulosic break down deciphered using molecular docking studies. 利用分子对接研究揭示了昆虫内源性纤维素酶对木质纤维素分解的潜力。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-15 DOI: 10.1080/14786419.2023.2280169

Nivetha Ramanathan, Bhuvaragavan Sreeramulu, Meenakumari Mani, Janarthanan Sundaram

{"title":"Potential of insect endogenous cellulases for lignocellulosic break down deciphered using molecular docking studies.","authors":"Nivetha Ramanathan, Bhuvaragavan Sreeramulu, Meenakumari Mani, Janarthanan Sundaram","doi":"10.1080/14786419.2023.2280169","DOIUrl":"10.1080/14786419.2023.2280169","url":null,"abstract":"Insects possess cellulolytic system capable of producing variegate enzymes with multifarious specificities to break down complex lignocellulosic products. Astonishingly, endoglucanases, exoglucanases and β-glycosidases act sequentially in a synergistic system to facilitate the breakdown of cellulose to utilisable energy source glucose. In silico docking studies of endo-β-1,4-glucanase from 19 different insects belonging to six different orders identified that it possesses high affinity for all the six substrates, including CMC, cellulose, cellotriose, cellotetraose, cellopentose and cellohexaose. Additionally, β-glucosidase from nearly all the reported insect sources also showed considerable affinity towards cellobiose. Van der Waals, conventional hydrogen bonds and carbon-hydrogen bonds stabilise the interaction between the enzyme and different substrates. Molecular dynamics simulations also held up the stability of various complexes. Efficient breakdown of lignocelluloses-based substrates becoming a major focus of industrial and academic communities worldwide, this study can perhaps complement the propensity of insect cellulases for prospected applications.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4146-4154"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134647914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterisation and skin protection activities of polysaccharides from Schnabelia terniflora. 燕尾莲多糖的鉴定及皮肤保护活性研究。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-16 DOI: 10.1080/14786419.2023.2280791

Ying Zhao, Yixian Liu, Huoxiang Zhou, Wei Guo, Weidong Wang, Huiping Chen

引用次数: 0

A comprehensive review on ayurvedic herb Leptadenia reticulata (Jeevanti): a phytochemistry and pharmacological perspective. 从植物化学和药理的角度综述印度育吠陀草药网麻的研究进展。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-21 DOI: 10.1080/14786419.2023.2282119

Sonali Kumari, Ravi Saini, Aditi Bhatnagar, Abha Mishra

{"title":"A comprehensive review on ayurvedic herb Leptadenia reticulata (Jeevanti): a phytochemistry and pharmacological perspective.","authors":"Sonali Kumari, Ravi Saini, Aditi Bhatnagar, Abha Mishra","doi":"10.1080/14786419.2023.2282119","DOIUrl":"10.1080/14786419.2023.2282119","url":null,"abstract":"Leptadenia reticulata is a vital Ayurvedic medicinal herb, commonly known as Jivanti or Jiv, and contains revitalising, rejuvenating, and lactogenic activities. It has been used in traditional medicine for treating respiratory disorders, wounds, inflammation, cough, dehydration, tuberculosis, colitis, chickenpox, dysentery, eye diseases, night blindness, fever, and snake bites. It is a perennial herb of Indian origin belonging to the Asclepiadaceae family and has been utilised for its therapeutic properties since ancient times. It is a key ingredient in several marketed herbal drugs, including chyawanprash, speman, and leptaden. Several potent compounds, including β-sitosterol, γ-sitosterol, phytol, α-amyrin, β-amyrin, apigenin, reticulin, deniculatin, leptaculatin, diosmetin, and rutin are present in this herb and attributed various pharmacological activities, including antidiabetic, antimicrobial, antioxidant, anti-abortifacient, anticancer, antipyretic, analgesic, anti-inflammatory, and antiulcer properties. This review provides an in-depth analysis of the distribution, ethnobotanical use, botanical description, phytocompounds, and pharmacological activities of Leptadenia reticulata.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4234-4260"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First report on the chemical composition and the free radical scavenging and antimicrobial activities of the essential oil of Ononis aurasiaca, an endemic plant of Algeria. 阿尔及利亚特有植物aurasiaca Ononis精油的化学成分、自由基清除和抗菌活性首次报道。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-16 DOI: 10.1080/14786419.2023.2282113

Khadidja Messaoudi, Tarek Benmeddour, Guido Flamini

{"title":"First report on the chemical composition and the free radical scavenging and antimicrobial activities of the essential oil of Ononis aurasiaca, an endemic plant of Algeria.","authors":"Khadidja Messaoudi, Tarek Benmeddour, Guido Flamini","doi":"10.1080/14786419.2023.2282113","DOIUrl":"10.1080/14786419.2023.2282113","url":null,"abstract":"This study represents the first investigation of the chemical composition and the antioxidant and antimicrobial activities of Ononis aurasiaca Förther & Podlech, a plant species endemic to the Aures Mountains of Algeria. The essential oil of the plant aerial parts was analysed using GC-MS. The in vitro antioxidant activity was evaluated using three methods. A total of 44 compounds were identified. The major constituents were dodecanal, hexahydrofarnesylacetone, 2-tridecanone, phytol, 1-heneicosene, and n-heneicosane. The oil displayed significant activity in the β-carotene bleaching assay, moderate scavenging activity against DPPH radicals and a low ability to reduce iron ions. Antibacterial tests conducted on four strains revealed effectiveness primarily against Gram-positive strains, specifically Staphylococcus aureus ATCC 25923 and ATCC 43300, while showing limited impact on Gram-negative strains, Pseudomonas aeruginosa ATCC 27853 and Escherichia coli ATCC 25922. Antifungal activity tests involving two moulds revealed a stronger inhibition against Scedosporium apiospermum compared to Aspergillus niger.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4355-4367"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136398333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive review of phytochemistry, pharmacology and clinical application of Gentianae Macrophyllae Radix. 龙胆草植物化学、药理学和临床应用综述。

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-12-26 DOI: 10.1080/14786419.2023.2298724

Chenwang Liu, Xiaomei Song, Yu Sun, Yuze Li, Xin Li, Dongdong Zhang

引用次数: 0

Molecular properties, structure, neurotrophic and anti-inflammatory activities of cultured secondary metabolites from the cultures of the mushroom Cyathus striatus CBPFE A06. 蘑菇Cyathus striatus CBPFE A06培养次生代谢物的分子特性、结构、神经营养和抗炎活性

IF 1.9 3区化学

Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-10-25 DOI: 10.1080/14786419.2023.2273911

Jing Wei, Mei-Yu Ye, Zhen-Xin Wang, Yi-Lin Zhang, Xuan-Sheng Hu, He-Ping Hui, Yi-Tong Liu, Jianzhao Qi

{"title":"Molecular properties, structure, neurotrophic and anti-inflammatory activities of cultured secondary metabolites from the cultures of the mushroom Cyathus striatus CBPFE A06.","authors":"Jing Wei, Mei-Yu Ye, Zhen-Xin Wang, Yi-Lin Zhang, Xuan-Sheng Hu, He-Ping Hui, Yi-Tong Liu, Jianzhao Qi","doi":"10.1080/14786419.2023.2273911","DOIUrl":"10.1080/14786419.2023.2273911","url":null,"abstract":"Two previously undescribed natural cyathane diterpenoids Me-dentifragilin A (1) and Epi-neocyathin O (2), and three known cyathane diterpenoids 3-5, cyathin O, neocyathin P, and cyathin I, were isolated from the rice medium of the Cyathus striatus CBPFE A06. Their structures were established by NMR spectra, and HR-ESI-MS. Compounds 1-5 displayed encouraging neurotrophic activity in PC-12 cells at doses of 5 µM. Meanwhile, 1-5 significantly inhibited LPS-induced NO generation in BV2 cells with the IC50 values ranging from 2.44 ± 0.16 to 4.33 ± 0.32 μM. Western blot analysis showed that 2 and 4 inhibited the expression of genes involved in nitric oxide (NO) production. Molecular docking revealed that five residues of inducible NO synthase (iNOS) are key residues affecting the interaction of 2 and 4 with iNOS. This study enriches the structural diversity of cyathane diterpenes and adds to the evidence that cyathane diterpenes prevent and treat neurodegenerative diseases.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4280-4285"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50158389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0