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Identification of potential antiviral compounds from Egyptian marine algae against influenza A virus. 埃及海藻抗甲型流感病毒潜在抗病毒化合物的鉴定。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-22 DOI: 10.1080/14786419.2023.2284865
Bassel M Hassen, Sarah H Rashedy, Ahmed Mostafa, Noura Mahrous, Mohamed S Nafie, Dalia Elebeedy, A Z Abdel Azeiz
{"title":"Identification of potential antiviral compounds from Egyptian marine algae against influenza A virus.","authors":"Bassel M Hassen, Sarah H Rashedy, Ahmed Mostafa, Noura Mahrous, Mohamed S Nafie, Dalia Elebeedy, A Z Abdel Azeiz","doi":"10.1080/14786419.2023.2284865","DOIUrl":"10.1080/14786419.2023.2284865","url":null,"abstract":"<p><p>Influenza is a contagious viral infection of the respiratory tract, affecting nearly 10% of the world's population, each year. The aim of this study was to extract and identify antiviral compounds against the influenza-A virus (H1N1) from different species of Egyptian marine algae. Three samples of marine macroalgae species were extracted and the antiviral activity of the extracts were tested on Madin Darby Canine Kidney cells. The bioactive compounds present in the most active fractions were identified using gas chromatography-mass spectrometry (GC-MS), then the binding potentials of the identified compounds were examined towards neuraminidase (NA) of the influenza-A virus using molecular docking. The methanolic extract of <i>Sargassum aquifolium</i> showed promising <i>in-vitro</i> antiviral activity with a selectivity index (SI) value of 101. The GC-MS analysis showed twelve compounds and the molecular docking analysis found that tetradecanoic acid showed the strongest binding affinities towards the NA enzyme.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4411-4418"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jerusalem artichoke diversity in Türkiye: comparative analysis of clone and organ-based biochemical composition. 以色列菊芋在<s:1> rkiye的多样性:克隆与器官生化组成的比较分析。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-15 DOI: 10.1080/14786419.2023.2280729
Fatih Hanci, Zelal Inan, Akife Dalda Şekerci, Aydın Uzun
{"title":"Jerusalem artichoke diversity in Türkiye: comparative analysis of clone and organ-based biochemical composition.","authors":"Fatih Hanci, Zelal Inan, Akife Dalda Şekerci, Aydın Uzun","doi":"10.1080/14786419.2023.2280729","DOIUrl":"10.1080/14786419.2023.2280729","url":null,"abstract":"<p><p>In this study, biochemical analyses were performed for the first time on 22 different Jerusalem artichokes clones collected from different regions of Türkiye and samples from three different organs of each clone, considering the interaction effects. As a result of the study, the interaction effect of clones and sampled organs was found significant for total flavonoids, ascorbic acid, total chlorophyll, pH, H<sub>2</sub>O<sub>2</sub> removal capacity, total dry matter, water soluble dry matter and antioxidant capacity <i>via</i> FRAP. According to the correlation analysis, the highest coefficient among the parameters in the tuber was between titratable acidity and total phenolic matter (0,576). Principal component analysis was used to assess the degree to which the parameters explained the variation in the gene pool. Factors directly and indirectly affecting the amount of water-soluble dry matter in the tuber were examined by path analysis.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4175-4180"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134647912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of phenolic compounds in Eugenia uniflora leaves by ESI(-) FT-ICR MS, analysis of cytotoxic activity on gastric adenocarcinoma (AGS cells), and anti-Helicobacter pylori activity. 用ESI(-) FT-ICR质谱分析单叶Eugenia叶片中酚类化合物的性质、对胃腺癌(AGS)细胞的细胞毒活性和抗幽门螺杆菌活性。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-17 DOI: 10.1080/14786419.2023.2276390
Fernanda M G de Oliveira, Jéssica Rodrigues Pereira de Oliveira Borlot, Rodrigo Rezende Kitagawa, Rita de Cássia Ribeiro Gonçalves, Rita Carolina Batista de Oliveira Filpo, Ricardo Machado Kuster
{"title":"Characterization of phenolic compounds in <i>Eugenia uniflora</i> leaves by ESI(-) FT-ICR MS, analysis of cytotoxic activity on gastric adenocarcinoma (AGS cells), and anti-<i>Helicobacter pylori</i> activity.","authors":"Fernanda M G de Oliveira, Jéssica Rodrigues Pereira de Oliveira Borlot, Rodrigo Rezende Kitagawa, Rita de Cássia Ribeiro Gonçalves, Rita Carolina Batista de Oliveira Filpo, Ricardo Machado Kuster","doi":"10.1080/14786419.2023.2276390","DOIUrl":"10.1080/14786419.2023.2276390","url":null,"abstract":"<p><p><i>Eugenia uniflora</i> leaves are a source of flavonoids and ellagitannins, and the Brazilian population uses them to treat various diseases, including gastrointestinal disorders. This study aimed to determine if the ethanol extract and other derivatives are effective cytotoxic agents against gastric adenocarcinoma (AGS cells) and anti-<i>H. pylori</i> agent, its chemical composition, and mass spectrometry characterization of the more abundant compounds. The results were compared with the literature. The aqueous fraction, rich in Oenothein B and Gemin D/Hippomanin A, showed anti-<i>H. pylori</i> activity and higher cytotoxicity on AGS cells compared to the other samples analysed. Furthermore, the ESI(-) FT-ICR MS characterized the more abundant phenolic compounds, including Quinic Acid, Myricitrin, Gemin D/Hippomanin A, and Oenothein. Therefore, the activity of the ethanolic extract and aqueous fraction for gastric cancer and against <i>H-pylori</i> seems to originate from the antiproliferative and bacteriostatic effects of tannins and flavonoids.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4297-4301"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136398331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genus Monanthotaxis: a review on distribution, ethnomedicinal uses and phytochemistry. Monanthotaxis属：分布、民族药用和植物化学综述。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2024-01-23 DOI: 10.1080/14786419.2024.2301743
James G Mayeka, Stephen S Nyandoro, Joan J E Munissi
{"title":"Genus <i>Monanthotaxis</i>: a review on distribution, ethnomedicinal uses and phytochemistry.","authors":"James G Mayeka, Stephen S Nyandoro, Joan J E Munissi","doi":"10.1080/14786419.2024.2301743","DOIUrl":"10.1080/14786419.2024.2301743","url":null,"abstract":"<p><p>This article reviews the geographical distribution, ethnomedicinal applications, and phytochemistry of the genus <i>Monanthotaxis</i> Baill, tribe Uvariae of the family Annonaceae. The reviewed works of literature were collected from various electronic databases including Google Scholar, PubMed, Science Direct, The International Plant Names Index (IPNI), and Research Gate. During this review, ninety-eight species of the genus <i>Monanthotaxis</i> were found to be widely distributed in tropical Africa. Some of those species are used in folkloric medicine by various communities to manage diseases and disease conditions such as fever, vomiting, headache, stomach-ache, malaria, helminthiasis, and hysteria. In the past 44 years (1979 to 2023), one hundred and nineteen secondary metabolites with different biomedical potentials have been reported from this genus. The reported compounds are categorised into flavonoids, alkaloids, terpenoids, polyoxygenated cyclohexane, and cyclohexene derivatives, benzyl derivatives, cinnamic acid derivatives, and stilbenoids. Most of the reported compounds showed an array of bioactivities corroborating the use of some members of the genus in folkloric medicine.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4494-4510"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139521474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemical composition and biological activities of essential oil from Grewia bulot leaves. 葛叶精油的化学成分和生物活性。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-01 DOI: 10.1080/14786419.2023.2275739
Ty Viet Pham, Duc Viet Ho, Anh Tuan Le, Y Duy Ngo, Nhan Thanh Thi Dang, Thang Quoc Le, Bao Chi Nguyen
{"title":"Chemical composition and biological activities of essential oil from <i>Grewia bulot</i> leaves.","authors":"Ty Viet Pham, Duc Viet Ho, Anh Tuan Le, Y Duy Ngo, Nhan Thanh Thi Dang, Thang Quoc Le, Bao Chi Nguyen","doi":"10.1080/14786419.2023.2275739","DOIUrl":"10.1080/14786419.2023.2275739","url":null,"abstract":"<p><p>This study focused on the chemical composition and biological activities of the essential oil derived from <i>Grewia bulot</i>, a plant species known for its medicinal properties. The analysis of <i>Grewia bulot</i> essential oil revealed the presence of 78 constituents. The major compounds were <i>α</i>-cadinol (13.5%), 1,8-cineole (12.7%), 1,10-di-<i>epi</i>-cubenol (9.8%), <i>epi</i>-<i>α</i>-cadinol (6.7%), (<i>E</i>,<i>E</i>)-<i>α</i>-farnesene (5.9%), (<i>E</i>)-citral (4.0%), selin-11-en-4-<i>α</i>-ol (4.0%), citronellol isobutanoate (3.9%), and geranic acid (3.7%). The essential oil exhibited promising antioxidant potential with an IC<sub>50</sub> value of 452.65 ± 28.40 µg/mL in DPPH model. This oil did not show NO production inhibitory effect in RAW 264.7 cells. In addition, the essential oil exhibited significant cytotoxicity against KB, Hep-G2, MCF-7, and SK-LU-1 cancer cell lines, with IC<sub>50</sub> values ranging from 44.04 ± 1.47 to 74.20 ± 3.71 μg/mL.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4106-4112"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71425215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cocoa as immunomodulatory agent: an update. 可可作为免疫调节剂：最新进展。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-01 DOI: 10.1080/14786419.2023.2272025
Maria Atanassova, Miquel Martorell, Farukh Sharopov, Lyubomir Atanassov, Pradeep Kumar, Javad Sharifi-Rad, Silvia Tejada-Gavela, Marcello Iriti, Raffaele Pezzani, Elena Maria Varoni
{"title":"Cocoa as immunomodulatory agent: an update.","authors":"Maria Atanassova, Miquel Martorell, Farukh Sharopov, Lyubomir Atanassov, Pradeep Kumar, Javad Sharifi-Rad, Silvia Tejada-Gavela, Marcello Iriti, Raffaele Pezzani, Elena Maria Varoni","doi":"10.1080/14786419.2023.2272025","DOIUrl":"10.1080/14786419.2023.2272025","url":null,"abstract":"<p><p>Cocoa is rich in polyphenols, mainly flavonoids, which correlate with several health benefits mediated by their antioxidant, anti-inflammatory and immunomodulatory properties. Cocoa and chocolate consumption have been reported to impact the regulation of the immune system, both in preclinical studies and in human trials. The mechanisms for immunomodulation can involve different effects of cocoa polyphenols on the immune system, acting as anti-inflammatory, antioxidant and anti-allergic agents, as well as the direct influence of cocoa on innate and acquired immunity, with cytokines production and activation of both lymphocyte-dependent and -independent pathways. Cocoa intake has been also correlated to changes in gut microbiota ecology and composition, also affecting the intestinal immune system. This review summarises the updates of the last two decades on cocoa as immunomodulatory agent and explores the health-related benefits of cocoa and chocolate intake.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4196-4207"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71425217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis and cytotoxic activity of some (+)-salsolidine derivatives. 某些(+)-固体碱衍生物的合成及其细胞毒活性。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-10-24 DOI: 10.1080/14786419.2023.2273924
Alena Koval'skaya, Arthur Gil'mutdinov, Alexander Lobov, Dmitry Tsypyshev, Vener Vakhitov, Inna Tsypysheva, Vladimir Dokichev, Yulia Vakhitova
{"title":"Synthesis and cytotoxic activity of some (+)-salsolidine derivatives.","authors":"Alena Koval'skaya, Arthur Gil'mutdinov, Alexander Lobov, Dmitry Tsypyshev, Vener Vakhitov, Inna Tsypysheva, Vladimir Dokichev, Yulia Vakhitova","doi":"10.1080/14786419.2023.2273924","DOIUrl":"10.1080/14786419.2023.2273924","url":null,"abstract":"<p><p>On the basis of typical for secondary amino group reactions a number of derivatives of alkaloid (+)-salsolidine was synthesised. Cytotoxic properties of obtained compounds towards the HEK293, A549, MCF-7 and SH-SY5Y cell lines have been evaluated. As a result of the screening, the hit compound - 2-(chloroacetyl)-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline (<b>11</b>) was identified, that inhibited the metabolic activity of A-549, MCF-7 and SH-SY5Y tumour cell lines with the IC<sub>50</sub> values of 3.83 ± 0.78 µM, 5.84 ± 1.62 µM and 2.89 ± 0,92 µM correspondingly. Based on the effect of <b>11</b> on the cell cycle progression and the molecular docking data, it was preliminary assumed that the cytotoxic activity of the <b>11</b> can be realised through its interaction with the active site of the cyclin-dependent kinase CDK9 (PDB code 3BLR).</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4092-4097"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50158390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Effect of total phenol on the control of leafminer (Phytomyza horticola) infestation in Pea plants". 总酚对豌豆叶螨(Phytomyza horticola)侵染的防治效果
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-16 DOI: 10.1080/14786419.2023.2282115
Gunjali Dengta, Tanuja Banshtu, Subhash Chander Verma, Neha Gautam, Priyanka Sharma
{"title":"\"Effect of total phenol on the control of leafminer (<i>Phytomyza horticola</i>) infestation in Pea plants\".","authors":"Gunjali Dengta, Tanuja Banshtu, Subhash Chander Verma, Neha Gautam, Priyanka Sharma","doi":"10.1080/14786419.2023.2282115","DOIUrl":"10.1080/14786419.2023.2282115","url":null,"abstract":"<p><p>To determine how vulnerable various pea genotypes are to leafminer infestation, a field experiment was conducted. On the basis of the presence of mines on five randomly selected leaflets from the upper, middle and lower parts of the plant, observations of larvae were made throughout the growing season. The total phenols were determined using the method described by Bray and Thorpe (1954, Analysis of phenolic compounds of interest in metabolism. <i>Methods Biochem Anal</i>. 52:1-27) and absorbance at 650 nm was measured using a spectrophotometer. There was a negative correlation between leafminer infestation and total phenol content. The UHF Pea-12 genotype, characterised by the lowest total phenol concentration (20.87 mg/100 g), exhibited the highest level of leaflet infestation (17.33%). Although UHF Pea-1 genotype had the lowest mean leaflet infestation (6.58%), it also had the highest phenol concentration (41.91 mg per 100 g). In context with this, the present study highlights the significance of host-plant resistance (HPR) in pest management.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4368-4374"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136398328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of Trifolium repens L. from the Indian Himalayan region as a phyto-therapeutic agent. 印度喜马拉雅地区的三叶草（Trifolium repens L.）作为植物治疗剂的研究。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2024-01-04 DOI: 10.1080/14786419.2023.2299319
Leirika Ngangom, Divya Venugopal, Neha Pandey
{"title":"Investigation of <i>Trifolium repens</i> L. from the Indian Himalayan region as a phyto-therapeutic agent.","authors":"Leirika Ngangom, Divya Venugopal, Neha Pandey","doi":"10.1080/14786419.2023.2299319","DOIUrl":"10.1080/14786419.2023.2299319","url":null,"abstract":"<p><p><i>Trifolium repens</i> is a well-known herbaceous, perennial herb and has been extensively used in the traditional medicine system over the years. Various parts of the plant are traditionally used as a curative agent against several health ailments such as skin problems, wound healing, stomach disorders, sedative, fever, antiseptic, analgesic, expectorant, psoriasis and eczema. To maximise the plant's potential for usage in the future, the review also aims to update information about its significant pharmacological properties. The ethnomedicinal benefits of <i>T. repens</i> have been well studied; however, the facets of the plant have not been explored yet. The current review outlines several bioactive compounds quantified from <i>T. repens</i> and a few of them namely quercetin, kaempferol, myricetin, acacetin and linamarin, have been reported to have biological activities such as antibacterial, antifungal, antileishmanial, anti-inflammatory, antiaging and anti-hepatotoxic activities. A significant number of <i>in vitro</i> studies have been done on the plant extract, but little is known about the isolation and efficacy of the potent natural bioactive compounds of <i>T. repens</i>. The bioactive compounds in <i>T. repens</i> can be used for advanced drug development against various health disorders.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4468-4478"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the bioactive components and antioxidant activities of wild-type Zanthoxylum nitidum roots from various regions of Southern China. 华南不同地区野生型黑椒根的生物活性成分及抗氧化活性比较。
IF 1.9 3区 化学
Natural Product Research Pub Date : 2024-12-01 Epub Date: 2023-11-22 DOI: 10.1080/14786419.2023.2284264
Jun He, Jiaxin Zeng, Liqi Zeng, Leilei Yang, Qing Ma, Hong Wu, Yang Yang
{"title":"Comparison of the bioactive components and antioxidant activities of wild-type <i>Zanthoxylum nitidum</i> roots from various regions of Southern China.","authors":"Jun He, Jiaxin Zeng, Liqi Zeng, Leilei Yang, Qing Ma, Hong Wu, Yang Yang","doi":"10.1080/14786419.2023.2284264","DOIUrl":"10.1080/14786419.2023.2284264","url":null,"abstract":"<p><p><i>Zanthoxylum nitidum</i> is a traditional Chinese herb, but limited information is available concerning its antioxidant activity of <i>Z. nitidum</i>. In this study, the bioactive components, content, and antioxidant activity of <i>Z. nitidum</i> roots from various regions in southern China were detected and evaluated. The results revealed that the highest nitidine chloride content found in S13. The S1 contained significantly higher concentrations of hesperidin, total flavonoids, and total phenols than other samples. The samples from S13, S1, and S12 had the strongest comprehensive antioxidant activity. Stoichiometric analysis revealed that samples from various regions were effectively identified and classified. This is the first study to investigate the antioxidant activity of wild-type <i>Z. nitidum</i> in southern China. It lays the groundwork for <i>Z. nitidum</i> harvesting, origin identification, sensible use, as well as the quality evaluation of <i>Z. nitidum</i> resources, particularly <i>in vitro</i> antioxidant activity assessment.</p>","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"4399-4410"},"PeriodicalIF":1.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138291421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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