Jesse Gordon Bendetson, Helen Tran, Mina Sophia Kamangar, Keren Fogelfeld, Cecilia Matilda Jude, Nader Kamangar
{"title":"CT findings in biomass smoke-associated interstitial lung disease: A retrospective analysis.","authors":"Jesse Gordon Bendetson, Helen Tran, Mina Sophia Kamangar, Keren Fogelfeld, Cecilia Matilda Jude, Nader Kamangar","doi":"10.25259/JCIS_225_2025","DOIUrl":"10.25259/JCIS_225_2025","url":null,"abstract":"<p><strong>Objectives: </strong>Household air pollution from biomass fuel combustion remains a major global health burden, affecting nearly 3 billion people worldwide. Although biomass smoke exposure is a recognized risk factor for chronic airway disease, its role in interstitial lung disease (ILD) is less well defined, and characteristic CT features have not been systematically described in patients without coexisting chronic obstructive pulmonary disease (COPD).</p><p><strong>Material and methods: </strong>We conducted a retrospective review of 23 patients with biomass smoke exposure and radiographic evidence of ILD, excluding those with alternative ILD etiologies or pre-existing COPD. CT scans were independently assessed by a thoracic radiologist and two pulmonologists for predominant patterns, distributions, and additional findings, with consensus classification. We report proportions with 95% confidence intervals (CIs) and performed exploratory Spearman correlation to assess associations between selected CT features.</p><p><strong>Results: </strong>The cohort (mean age 71.7 years; all females; 96% born outside the United States) most commonly demonstrated reticulation (16/23, 70%; 95% CI, 49-84%), ground-glass opacities (GGO) (15/23, 65%; 95% CI, 45-81%), mosaic attenuation (15/23, 65%; 95% CI, 45-81%), and bronchial wall thickening (14/23, 61%; 95% CI, 41-78%). Abnormalities were typically patchy (18/23, 78%; 95% CI, 58-90%) and peribronchial (13/23, 57%; 95% CI, 37-74%), without consistent apical or basal predominance. Traction bronchiectasis occurred in 12/23 (52%; 95% CI, 33-71%) and lymphadenopathy in 9/23 (39%; 95% CI, 22-59%). Honeycombing (5/23, 22%; 95% CI, 10-42%), centrilobular emphysema (4/23, 17%; 95% CI, 7-37%), nodules (3/23, 13%; 95% CI, 5-32%), cysts (2/23, 9%; 95% CI, 2-27%), tree-in-bud opacities (2/23, 9%; 95% CI, 2-27%), and centrilobular nodularity (1/23, 4%; 95% CI, 1-21%) were uncommon. Exploratory Spearman analyses showed strong associations between mosaic attenuation and bronchial wall thickening (ρ = 0.91) and between peribronchial distribution and mosaic attenuation (ρ = 0.83), with additional positive correlations between mosaic attenuation and bronchiectasis (ρ = 0.70), peribronchial distribution and bronchial wall thickening (ρ = 0.73), bronchial wall thickening and bronchiectasis (ρ = 0.77), bronchiectasis and traction bronchiectasis (ρ = 0.57), and reticulation and traction bronchiectasis (ρ = 0.69). Exploratory Spearman correlation analyses showed strong associations between mosaic attenuation and bronchial wall thickening (ρ = 0.91) and between peribronchial distribution and mosaic attenuation (ρ = 0.83), with additional positive correlations between mosaic attenuation and bronchiectasis (ρ = 0.70), peribronchial distribution and bronchial wall thickening (ρ = 0.73), bronchial wall thickening and bronchiectasis (ρ = 0.77), bronchiectasis and traction bronchiectasis (ρ = 0.57), and reticulation and traction ","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"17"},"PeriodicalIF":1.1,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13157916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147874155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica Duan, Cody King, Joseph Hatem, Joel Thompson
{"title":"<i>Mycobacterium genavense</i> infection of the adrenal gland - A case report.","authors":"Jessica Duan, Cody King, Joseph Hatem, Joel Thompson","doi":"10.25259/JCIS_134_2025","DOIUrl":"10.25259/JCIS_134_2025","url":null,"abstract":"<p><p>Adrenal masses are increasingly detected incidentally on imaging due to the widespread use of advanced imaging modalities and require a multidisciplinary approach for accurate diagnosis and management. This case report describes a patient who initially presented with lower extremity deep vein thrombosis and was found to have a right adrenal mass upon cross-sectional imaging. Atypical features noted on further imaging prompted investigation of the mass, with histopathologic analysis and PCR sequencing ultimately identifying <i>Mycobacterium genavense</i> infection as the cause. This case highlights the importance of maintaining a broad differential for incidental adrenal findings and the critical role of histopathology for definitive diagnosis.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"16"},"PeriodicalIF":1.1,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13157948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147874144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Apparent diffusion coefficient values in prostate cancer: Association with pathological grade groups and correlation with Ki-67 proliferation index.","authors":"Yanqiu Wu, Linbo Shi, Dan Wang","doi":"10.25259/JCIS_125_2025","DOIUrl":"10.25259/JCIS_125_2025","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of the study is to investigate the diagnostic value of apparent diffusion coefficient (ADC) parameters in differentiating prostate cancer (PCa) pathology grading groups (GG) and their correlation with Ki-67 proliferation index.</p><p><strong>Material and methods: </strong>This single-center retrospective study analyzed magnetic resonance imaging data from 119 pathologically confirmed PCa cases with documented Ki-67 proliferation indices. Both mean ADC (ADC<sub>mean</sub>) and minimum ADC (ADC<sub>min</sub>) values were obtained from dominant lesions using ADC mapping. Comparative analysis was performed between high-risk PCa (hPCa) and non-high-risk PCa (nhPCa) groups. Diagnostic performance was assessed through receiver operating characteristic (ROC) curve analysis, while Spearman correlation was employed to evaluate relationships between ADC parameters, GG, and Ki-67 index.</p><p><strong>Results: </strong>Significantly lower ADC<sub>mean</sub> and ADC<sub>min</sub> values were observed in hPCa compared to nhPCa (<i>P</i> < 0.001). ROC analysis demonstrated the diagnostic utility of ADC parameters in distinguishing hPCa from nhPCa. Both ADC<sub>mean</sub> and ADC<sub>min</sub> showed significant negative correlations with GG and Ki-67 proliferation index (<i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>This study demonstrates an inverse correlation between ADC values and tumor proliferative activity in PCa, providing biological validation for DWI in assessing tumor aggressiveness. While this quantitative parameter shows potential for risk stratification, its application requires further multicenter validation.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"15"},"PeriodicalIF":1.1,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13157925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147874056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benjamin Jyhhan Kuo, Felicia Hui Xian Chin, Sung Hock Chew, Li Ching Lau
{"title":"Post-ovarian cystectomy imaging appearances for borderline ovarian tumors: Pearls and pitfalls.","authors":"Benjamin Jyhhan Kuo, Felicia Hui Xian Chin, Sung Hock Chew, Li Ching Lau","doi":"10.25259/JCIS_197_2025","DOIUrl":"10.25259/JCIS_197_2025","url":null,"abstract":"<p><p>The Ovarian-Adnexal Reporting and Data System (O-RADS) ultrasound and MRI lexicon guidelines have standardized preoperative assessment of adnexal masses and improved communication with clinicians. However, in premenopausal women who have undergone ovarian cystectomy, post-operative ovarian appearances may mimic indeterminate or suspicious lesions, posing interpreting challenges. This illustrative educational case series highlights characteristic post-operative imaging features following cystectomy for borderline ovarian tumors (BOTs), emphasizing some common pearls and pitfalls. The cases underscore that while O-RADS is validated for preoperative adnexal assessment, post-operative ovaries constitute a recognized gray zone where familiarity with these imaging nuances is crucial for accurate interpretation.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"14"},"PeriodicalIF":1.1,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13157898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147874205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Erratum: Ramezanpour S, Vulasala SS, Sharma S, Sharma S. An unusual case of breast cancer masked by hidradenitis suppurative. J Clin Imaging Sci. 2025;15:44.","authors":"","doi":"10.25259/JCIS_43_2025_ER","DOIUrl":"10.25259/JCIS_43_2025_ER","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.25259/JCIS_43_2025.].</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"13"},"PeriodicalIF":1.1,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054320/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lulu Zhang, Xianghao Feng, He Zhang, Dapeng Zhang, Houliang Zhao, Qihang Sun, Yankai Meng, Cunjie Sun
{"title":"Optimization of image quality and diagnostic accuracy for vascular stenosis in computed tomography perfusion-reconstructed cerebral computed tomography angiography using deep learning reconstruction.","authors":"Lulu Zhang, Xianghao Feng, He Zhang, Dapeng Zhang, Houliang Zhao, Qihang Sun, Yankai Meng, Cunjie Sun","doi":"10.25259/JCIS_226_2025","DOIUrl":"10.25259/JCIS_226_2025","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to compare the effects of deep learning image reconstruction (DLIR) and adaptive statistical iterative reconstruction-veo (ASIR-V) algorithms on the image quality of cranial computed tomography angiography (CTA) reconstructed from computed tomography perfusion (CTP) data and to evaluate their agreement with digital subtraction angiography (DSA), the gold standard for diagnosing arterial stenosis.</p><p><strong>Material and methods: </strong>This retrospective study enrolled patients with clinically suspected cerebrovascular disease who had undergone CTP examination. From the arterial peak phase of CTP raw data, four CTA datasets were reconstructed: ASIR-V 40%, ASIR-V 80%, DLIR low setting (DLIR-L), and DLIR high setting (DLIR-H). Regions of interest were placed at the M1 segment of the middle cerebral artery (MCA), basilar artery (BA), and internal carotid artery (ICA) on the healthy side and the temporalis muscle. Computed tomography attenuation values and standard deviations were measured, and the contrast-to-noise ratio(CNR) and signal-to-noise ratio (SNR) were subsequently calculated using the attenuation values and standard deviations. Vessel edge sharpness was objectively assessed using edge rise distance (ERD) and edge rise slope (ERS). Using DSA as the reference standard, diagnostic performance for vascular stenosis was evaluated, and agreement was analyzed with the Kappa test. Two radiologists independently scored subjective image quality using a 5-point Likert scale.</p><p><strong>Results: </strong>Sixty-five patients were included, 14 of whom additionally underwent DSA. For the MCA, ICA, and BA, image noise in the DLIR-H group was significantly lower than that in the other groups, with statistically significant differences compared with ASIR-V 40% (<i>p</i> < 0.05). For CNR and SNR, DLIR-H and ASIR-V 80% outperformed ASIR-V 40% and DLIR-L across all arterial levels (<i>p</i> < 0.05). ERD and ERS were significantly superior in the DLIR groups compared with the ASIR-V groups (<i>p</i> < 0.05). In subjective evaluations, the DLIR-H group achieved the highest scores across all parameters (<i>p</i> < 0.05). Agreement with DSA was excellent for DLIR-H (κ = 0.819), significantly higher than for ASIR-V (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>In CTP examinations for suspected cerebrovascular disease, DLIR-H markedly improves cranial CTA image quality compared with ASIR-V, while achieving higher diagnostic agreement with DSA. DLIR-H can be recommended as the preferred clinical reconstruction method.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"12"},"PeriodicalIF":1.1,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Huang, Jonathan Gigas, Anthony Portanova, Deepinder Pal Singh
{"title":"Solitary extramedullary plasmacytoma of the nasopharynx: A case report.","authors":"Daniel Huang, Jonathan Gigas, Anthony Portanova, Deepinder Pal Singh","doi":"10.25259/JCIS_176_2025","DOIUrl":"10.25259/JCIS_176_2025","url":null,"abstract":"<p><p>Solitary extramedullary plasmacytoma (SEP) is a rare form of plasma cell neoplasm that occurs in the soft tissue without systemic involvement. We report the case of an 81-year-old female patient who presented with intermittent dysphagia and was found to have a right nasopharyngeal mass diagnosed as a plasmacytoma. Diagnostic workup included endoscopy, biopsy, imaging, and laboratory analysis, which ruled out multiple myeloma. The patient underwent definitive radiation therapy, and at evaluation 4 months later, there was no metabolic or endoscopic evidence of any disease, except for minor toxicity limited to nocturnal xerostomia. This case underscores the importance of timely diagnosis and the role of radiotherapy in treating SEP, particularly in uncommon anatomical locations.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"11"},"PeriodicalIF":1.1,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revisiting retrosplenial amnesia: Injury of the crus of the fornix following splenial hemorrhage - A 3D magnetic resonance imaging case report.","authors":"Shunji Mugikura, Naoko Mori","doi":"10.25259/JCIS_286_2025","DOIUrl":"10.25259/JCIS_286_2025","url":null,"abstract":"<p><p>Lesions involving the region immediately posterior to the splenium of the corpus callosum have traditionally been associated with \"retrosplenial amnesia.\" However, the crus of the fornix (FxCr), which runs immediately beneath the splenium, is anatomically vulnerable to secondary involvement that may be overlooked on conventional magnetic resonance imaging (MRI). Because the fornix constitutes a critical efferent pathway of the hippocampal Papez circuit, disruption of the FxCr can contribute to amnesia that may resemble the effects of retrosplenial cortical dysfunction. This possibility was raised in the original single-case description of \"retrosplenial amnesia,\" although direct assessment of the fornix was not feasible with the imaging techniques available at that time.\" We report an adult who developed episodic memory impairment following a splenial region hemorrhage with intraventricular extension. Formal neuropsychological assessment demonstrated profound anterograde amnesia with preservation of other cognitive functions, indicating selective impairment of episodic memory. Initial conventional MRI demonstrated that the hemorrhage was confined to the splenium of the corpus callosum, without definite involvement of the retrosplenial cortex. On follow-up imaging, high-resolution 3D T1-weighted MRI with multiplanar reconstruction revealed focal discontinuity of the left FxCr immediately beneath the splenial lesion with chronic encephalomalacia, while the hippocampi and medial temporal structures remained structurally intact. I-123 IMP single photon emission computed tomography showed hypoperfusion in the left hippocampus and the anterior and posterior cingulate gyri, without significant hypoperfusion in the retrosplenial region, consistent with downstream functional disruption of the Papez circuit secondary to FxCr disconnection. These findings provide contemporary structural and functional evidence that injury to the FxCr may represent a critical substrate of amnesia previously attributed primarily to retrosplenial lesions. Routine evaluation of the fornix, particularly the FxCr, should be incorporated into the diagnostic assessment of patients with splenial or retrosplenial pathology accompanied by amnesia.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"10"},"PeriodicalIF":1.1,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia R Keller, Ashmitha Arun, Avni Sanghvi, Prachi H Telkar, Chetan Chandulal Shah
{"title":"Experience with new technology: Point-of-care magnetic resonance imaging in the neonatal intensive care unit.","authors":"Olivia R Keller, Ashmitha Arun, Avni Sanghvi, Prachi H Telkar, Chetan Chandulal Shah","doi":"10.25259/JCIS_217_2025","DOIUrl":"10.25259/JCIS_217_2025","url":null,"abstract":"<p><p>Neuroimaging is a crucial component of the management of neonates in the neonatal intensive care unit (NICU). Previously, challenges associated with the transport of neonates to a traditional 1.5-3T magnetic resonance imaging (MRI) machine have led to a reliance on ultrasound in the NICU, despite its limitations. Bedside availability of the neonatal MRI system has provided solutions to some of these challenges by decreasing the time of transport, providing continuous monitoring of the neonate, and cable management for lines and leads without an external magnetic field. We present our initial experience with the point-of-care NICU MRI through a clinical case. The point-of-care MRI successfully identified intracranial abnormalities, demonstrating its effectiveness in the NICU.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"9"},"PeriodicalIF":1.1,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integration of dual-energy computed tomography and radiomics to improve noninvasive assessment of liver fibrosis: A retrospective study.","authors":"Takayuki Miyachi, Shintaro Ichikawa, Tatsunori Kobayashi, Akihiro Osugi, Ren Suzuki, Masatoshi Kakuya, Satoshi Funayama, Yukichi Tanahashi, Kumi Ozaki, Satoshi Goshima","doi":"10.25259/JCIS_255_2025","DOIUrl":"10.25259/JCIS_255_2025","url":null,"abstract":"<p><strong>Objectives: </strong>Few studies have used radiomics analysis to virtual monochromatic images (VMI) and material density images (MDI) for the assessment of liver fibrosis. Therefore, this retrospective study aimed to investigate whether integrating dual-energy computed tomography (CT) with radiomics analysis can predict Fibrosis-4 (FIB-4) index risk groups.</p><p><strong>Material and methods: </strong>A total of 137 patients were classified on the basis of the FIB-4 index: 40 as low-risk (FIB-4 index <1.3), 57 as intermediate-risk (1.3≤ FIB-4 index <2.67), and 40 as high-risk (FIB-4 index ≥2.67) for liver fibrosis. VMIs (70-keV and 40-keV images) and MDI (iodine-water images) were generated from the equilibrium-phase dual-energy CT data, and radiomic features were extracted from the same liver segmentation to develop models for distinguishing between FIB-4 risk groups.</p><p><strong>Results: </strong>Distinguishing between low-risk and high-risk groups yielded mean area under the curve (AUC) values (95% confidence intervals) of 0.69 (0.57-0.80) for the 70-keV images, 0.77 (0.67-0.88) for the 40-keV images, and 0.77 (0.66-0.87) for the iodine-water images, with statistically significant differences between the 70-keV images and the 40-keV (<i>P</i> = 0.01) and iodine-water images (<i>P</i> = 0.04). To distinguish between the low-risk and intermediate-risk groups, all image types showed similar AUC values ranging from 0.64 to 0.66, with no significant differences. For distinguishing intermediate-risk and high-risk groups, the 40-keV and iodine-water images showed a trend toward higher AUC values than the 70-keV images; however, no statistically significant differences were observed.</p><p><strong>Conclusion: </strong>This study demonstrates the feasibility of combining dual-energy CT with radiomics for noninvasive liver fibrosis risk stratification using the FIB-4 index.</p>","PeriodicalId":15512,"journal":{"name":"Journal of Clinical Imaging Science","volume":"16 ","pages":"8"},"PeriodicalIF":1.1,"publicationDate":"2026-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12954249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147355290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}