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Journal of Community Hospital Internal Medicine Perspectives最新文献

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COVID-19-related Pneumonitis in Immunocompromised Patients: Reviewing Clinical Features and Management Approaches. 免疫力低下患者的 COVID-19 相关肺炎：回顾临床特征和管理方法。
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1399
Adeel Nasrullah, Hassan Shakir, Eiraj Khan, Muhammad I Bilal, Abu B Sheikh, Khalid Malik, Tariq Cheema
{"title":"COVID-19-related Pneumonitis in Immunocompromised Patients: Reviewing Clinical Features and Management Approaches.","authors":"Adeel Nasrullah, Hassan Shakir, Eiraj Khan, Muhammad I Bilal, Abu B Sheikh, Khalid Malik, Tariq Cheema","doi":"10.55729/2000-9666.1399","DOIUrl":"https://doi.org/10.55729/2000-9666.1399","url":null,"abstract":"<p><p>In this case series, we explore persistent SARS-CoV-2 infection and its resultant pneumonitis within a cohort of immunocompromised patients. We elucidate the complex interplay between immunosuppression and COVID-19 by examining four patients who experienced prolonged viral shedding and recurrent respiratory failure due to their compromised immune systems. This series elucidates the clinical presentation, diagnostic challenges, and therapeutic strategies. We also summarize existing literature regarding persistent SARS-CoV-2 infection in immunocompromised individuals. Our findings support the use of a tailored treatment approach using a proposed diagnostic and management algorithm to standardize care and optimize outcomes.</p>","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Biphasic Presentation of Diffuse Large B-cell Lymphoma Metastasis to the Hypothalamus-pituitary Axis: A Case Report and Literature Review. 弥漫大 B 细胞淋巴瘤转移至下丘脑-垂体轴的双相表现：病例报告和文献综述。
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1393
Fadi Alghzawi, Maria Martinez-Cruz, Salman Z Bhat, Christopher J Haas
{"title":"A Biphasic Presentation of Diffuse Large B-cell Lymphoma Metastasis to the Hypothalamus-pituitary Axis: A Case Report and Literature Review.","authors":"Fadi Alghzawi, Maria Martinez-Cruz, Salman Z Bhat, Christopher J Haas","doi":"10.55729/2000-9666.1393","DOIUrl":"https://doi.org/10.55729/2000-9666.1393","url":null,"abstract":"<p><p>The Hypothalamus-Pituitary axis (HPA) is a rare location for metastasis of non-Hodgkin's lymphoma. Lymphomas constitute less than 0.5% of reported HPA metastasis. This case is unique in that, in addition to the noted panhypopituitarism; initial diagnostics demonstrated marked hyponatremia, consistent with syndrome of inappropriate antidiuretic hormone (SIADH), which was subsequently complicated by sudden diabetes insipidus (DI), suggesting hypothalamic/stalk infiltration. Despite low sensitivity, CSF cytology/flow cytometry may serve as a less invasive diagnostic measure. Treatment includes systemic chemotherapy with agents that cross the blood-brain barrier. Surgical resection alone or associated radiotherapy did not show an increase in survival. The prognosis remains poor.</p>","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Case of Idiopathic Thrombocytopenia Causing Retrobulbar Hemorrhage. 特发性血小板减少症导致视网膜出血的罕见病例。
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1379
Khawaja O Omar, William Sebastian, Amna Anees
{"title":"Rare Case of Idiopathic Thrombocytopenia Causing Retrobulbar Hemorrhage.","authors":"Khawaja O Omar, William Sebastian, Amna Anees","doi":"10.55729/2000-9666.1379","DOIUrl":"https://doi.org/10.55729/2000-9666.1379","url":null,"abstract":"<p><p>Immune thrombocytopenia purpura (ITP) is defined as a platelet count lower than 100 × 10ˆ9/L, in the absence of known abnormalities in white blood cells, normal hemoglobin with generalized purpuric rash: making it a diagnosis of exclusion.1-2 ITP is due to destruction of platelets in the spleen via autoantibodies, resulting in reduced platelet counts.3 Though rare, ITP is linked with spontaneous retrobulbar hemorrhage (SRH). If ITP is identified, prompt treatment is needed to prevent loss of vision. An 80-year-old non-smoking woman with a history of diabetes, hypertension, and alpha thalassemia minor presented with a one-day history of a right occipital lobe headache and right sided ocular dysfunction. Workup showed a very low platelet count of 35,000/mm<sup>3</sup>, and elevated D-Dimer at 12,485 ng/mL. MRI revealed a new hemorrhage in the retrobulbar area causing right-sided proptosis. MRA showed no arteriovenous shunting, and the right ophthalmic artery was patent. Therapy for seven days with cryoprecipitate, IVIG, and steroids was started, symptoms resolved, and patient was discharged. The relationship between ITP and non-traumatic sub-periosteal orbital hemorrhage (NTSOH) is unclear, but its occurrence in the setting of anemia is often seen. To best of our knowledge this is a rare case of NTSOH in a patient with mild anemia and acute ITP in the absence of other risk factors such as trauma or excessive Valsalva events.</p>","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intranasal Insulin for Treatment of Persistent Post-COVID-19 Olfactory Dysfunction: A Scoping Review. 鼻内胰岛素用于治疗 COVID-19 后持续性嗅觉障碍：范围综述。
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1390
Ali Karim, Arisha M G Pathan, Allah Warayo, Iftikhar Ahmed, Aminullah Betanai, Fnu Dropati, Saqlain Ahmed, Pir R J Sarhandi, Poonam Kumari, Raveena B Bansari, Amin Mehmoodi, Jahanzeb Malik
{"title":"Intranasal Insulin for Treatment of Persistent Post-COVID-19 Olfactory Dysfunction: A Scoping Review.","authors":"Ali Karim, Arisha M G Pathan, Allah Warayo, Iftikhar Ahmed, Aminullah Betanai, Fnu Dropati, Saqlain Ahmed, Pir R J Sarhandi, Poonam Kumari, Raveena B Bansari, Amin Mehmoodi, Jahanzeb Malik","doi":"10.55729/2000-9666.1390","DOIUrl":"https://doi.org/10.55729/2000-9666.1390","url":null,"abstract":"<p><p>Olfactory dysfunction has emerged as a prominent symptom of COVID-19, persisting in a subset of patients even after recovery. This scoping review aims to explore the potential of intranasal insulin as a treatment modality for persistent post-COVID-19 olfactory dysfunction. A comprehensive literature search was conducted to gather relevant studies examining the role of intranasal insulin in treating olfactory dysfunction, particularly in post-COVID-19 cases. Studies were included investigating intranasal insulin's mechanisms, efficacy, safety, and clinical outcomes. The review synthesizes findings from various studies suggesting the therapeutic potential of intranasal insulin in improving olfactory function. Research highlights the influence of intranasal insulin on neuroprotection, neurogenesis, and synaptic plasticity within the olfactory system, providing insights into its mechanisms of action. Furthermore, preliminary clinical evidence suggests improvements in olfactory sensitivity and intensity following intranasal insulin administration in post-COVID-19 patients with persistent olfactory dysfunction. While initial findings are encouraging, further rigorous investigations, including clinical trials with larger cohorts, are essential to validate these observations, ascertain optimal dosage regimens, and establish the safety and efficacy of intranasal insulin. This review provides a foundation for future research directions aimed at harnessing the therapeutic potential of intranasal insulin in addressing olfactory dysfunction following COVID-19.</p>","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemi-tongue Ischemia Due to Antiphospholipid Antibody Syndrome-A Case Report. 抗磷脂抗体综合征导致的半舌缺血--病例报告
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-09-09 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1385
Ateeb U Rahman, Amir S Kazi, Ali A Asif, Amna Chaudary
{"title":"Hemi-tongue Ischemia Due to Antiphospholipid Antibody Syndrome-A Case Report.","authors":"Ateeb U Rahman, Amir S Kazi, Ali A Asif, Amna Chaudary","doi":"10.55729/2000-9666.1385","DOIUrl":"https://doi.org/10.55729/2000-9666.1385","url":null,"abstract":"<p><p>Antiphospholipid antibody syndrome, also known as Hughes syndrome, is a multi-system autoimmune disorder characterized by recurrent thrombosis and fetal loss. The most common types of antiphospholipid antibodies include lupus anticoagulants, anticardiolipin antibodies, and anti-beta 2 glycoprotein 1 antibodies. Owing to the prothrombotic nature of this disease, diagnosing and treating the condition as early as possible is necessary. In this case report, we discuss the typical and atypical manifestations of this disease, as well as the current diagnostic and therapeutic options. We present a case of atypical antiphospholipid antibody syndrome in the form of hemi-tongue ischemia.</p>","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Metformin Discontinuation on Readmission Rate in Patients with Acute Heart Failure 停用二甲双胍对急性心力衰竭患者再入院率的影响
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-07-02 DOI: 10.55729/2000-9666.1366
Curtis Wong, Erica Junqueira, N. P. Poldiak, Nancy Crossley, Shantae Jenkins
{"title":"Influence of Metformin Discontinuation on Readmission Rate in Patients with Acute Heart Failure","authors":"Curtis Wong, Erica Junqueira, N. P. Poldiak, Nancy Crossley, Shantae Jenkins","doi":"10.55729/2000-9666.1366","DOIUrl":"https://doi.org/10.55729/2000-9666.1366","url":null,"abstract":"","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141686218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small Bowel Perforated Viscus Mimicking Inferior Wall Myocardial Infarction: A Case Report 模仿下壁心肌梗死的小肠穿孔内脏：病例报告
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-07-02 DOI: 10.55729/2000-9666.1337
Jesus Romero, Yezin F. Shamoon, Melvin Santana, Rachel Abboud, Ana L. Romero, Danna Reyes, Raja Pullatt
{"title":"Small Bowel Perforated Viscus Mimicking Inferior Wall Myocardial Infarction: A Case Report","authors":"Jesus Romero, Yezin F. Shamoon, Melvin Santana, Rachel Abboud, Ana L. Romero, Danna Reyes, Raja Pullatt","doi":"10.55729/2000-9666.1337","DOIUrl":"https://doi.org/10.55729/2000-9666.1337","url":null,"abstract":"","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IgA Nephropathy Secondary to COVID-19 infection - A Case report 继发于 COVID-19 感染的 IgA 肾病--一份病例报告
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-07-02 DOI: 10.55729/2000-9666.1370
Sanjivani Shrestha, S. K. Bandaru, M. K. Michael Siu, Silvia Malvica, Joselito T. Cabacar
{"title":"IgA Nephropathy Secondary to COVID-19 infection - A Case report","authors":"Sanjivani Shrestha, S. K. Bandaru, M. K. Michael Siu, Silvia Malvica, Joselito T. Cabacar","doi":"10.55729/2000-9666.1370","DOIUrl":"https://doi.org/10.55729/2000-9666.1370","url":null,"abstract":"","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sump Syndrome: The Forgotten Cause of Painless Jaundice in the Elderly 底盘综合征：被遗忘的老年人无痛性黄疸原因
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-07-02 DOI: 10.55729/2000-9666.1354
Mark Ayoub, Amna Anees
{"title":"Sump Syndrome: The Forgotten Cause of Painless Jaundice in the Elderly","authors":"Mark Ayoub, Amna Anees","doi":"10.55729/2000-9666.1354","DOIUrl":"https://doi.org/10.55729/2000-9666.1354","url":null,"abstract":"","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141688499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thromboembolic event in isolated non-compaction cardiomyopathy with multiple sclerosis 伴有多发性硬化症的孤立性非压迫性心肌病的血栓栓塞事件
IF 0.9
Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-07-02 DOI: 10.55729/2000-9666.1358
Comfort Olayioye, Indira Acharya, Christopher J. Haas
{"title":"Thromboembolic event in isolated non-compaction cardiomyopathy with multiple sclerosis","authors":"Comfort Olayioye, Indira Acharya, Christopher J. Haas","doi":"10.55729/2000-9666.1358","DOIUrl":"https://doi.org/10.55729/2000-9666.1358","url":null,"abstract":"","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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