Journal of Community Hospital Internal Medicine Perspectives最新文献

Rapidly Progressing Secondary Organizing Pneumonia in a Case of Systemic Sclerosis Sine Scleroderma - A Diagnostic Urgency: A Case Report and Literature Review.

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1442

Anish K Shrestha, Jyotsna Gummadi, Basem Al Achras, Nicholas E Ghionni

引用次数: 0

Primary Raynaud's Phenomenon.

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1443

Eliana A Alweis, Richard L Alweis

引用次数: 0

Oropharyngeal Lymphogranuloma Venereum: A Clinical Reasoning Challenge and Literature Review.

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1439

Andrew D Vogel, Anthony Asta, Hussam Ammar

引用次数: 0

Pulmonary Embolism in Long Standing Diabetes: A Hint Towards Pancreatic Carcinoma.

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1429

Anish K Shrestha, Christopher Haas

引用次数: 0

Clinical Characteristics, Microbiological and Risk Factors of Infections in Patients With Systemic Lupus Erythematosus.

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1447

Guanhua Li, Xiaojing Liu, Jiakang Zhao

{"title":"Clinical Characteristics, Microbiological and Risk Factors of Infections in Patients With Systemic Lupus Erythematosus.","authors":"Guanhua Li, Xiaojing Liu, Jiakang Zhao","doi":"10.55729/2000-9666.1447","DOIUrl":"10.55729/2000-9666.1447","url":null,"abstract":"Objective: To determine risk factors, clinical and microbiological characteristics of infections in a single-center systemic lupus erythematosus (SLE) cohort.Methods: All hospital patients in The First Affiliated Hospital of Zhengzhou University from 2019 to 2021 who meet ≥4 ACR-97 SLE criteria were identified. Patients with infection and without infection were included with a ratio of 1:2.Results: 687 SLE patients were identified and 224 patients with infection and 448 patients without infection were included. The most common microorganisms in the infection group were Escherichia coli, Herpes zoster and Aspergillus, respectively. In the cox regression analysis, nephritis (OR 1.785; 95% CI: 1.156-2.756), diabetes(OR 6.507; 95% CI: 2.692-15.725), CD4+ T cell (OR 1.003; 95% CI: 1.002-1.004), prednisone>10 mg/day (OR 1.879; 95% CI: 1.112-3.175), immunosuppressants (OR 0.465; 95% CI: 0.310-0.697) and SLEDAI score (OR 0.866; 95% CI: 0.837-0.896) were risk factors associated with infection.Conclusions: Bacteria was the most common infection in SLE patients with the respiratory tract being the most common site. Nephritis, diabetes, SLEDAI score were associated with infection. Monitoring CD4+ T cell can predict the infection incidence. Prednisone (>10 mg/day) and immunosuppressants increase the occurrence of infection.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"15 1","pages":"36-41"},"PeriodicalIF":0.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum Lactate Dehydrogenase Levels: The Grim Reaper Sign in Acute Pancreatitis?

IF 0.9

Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1430

George Trad, Jackson Hoekstra, Rakahn Haddadin, Kartika Shetty, John Ryan

{"title":"Serum Lactate Dehydrogenase Levels: The Grim Reaper Sign in Acute Pancreatitis?","authors":"George Trad, Jackson Hoekstra, Rakahn Haddadin, Kartika Shetty, John Ryan","doi":"10.55729/2000-9666.1430","DOIUrl":"10.55729/2000-9666.1430","url":null,"abstract":"Background and aims: Acute pancreatitis (AP) frequently presents in emergency departments and poses challenges in predicting severity and mortality. Established scoring systems like Ranson criteria, Acute Physiology And Chronic Health Evaluation II (APACHE) II, and Bedside Index of Severity in Acute Pancreatitis (BISAP) have varying effectiveness. Lactate dehydrogenase (LDH), an enzyme released during tissue damage, shows promise as a marker for organ injury in AP. This study aimed to evaluate LDH's potential to predict mortality risk and hospital stay duration in AP patients.Methods: A retrospective cohort study analyzed AP cases at HCA Healthcare facilities from January 2011 to January 2021. Among 514 patients with LDH data at admission, groups were categorized based on LDH levels. Outcomes included hospital and ICU stay lengths, mortality rates, and factors such as age, gender, race, BMI, and medical history.Results: Patients were stratified into three groups: Group 1 (<300 IU/L), Group 2 (300-600 IU/L), and Group 3 (>600 IU/L) based onLDHlevels. Patients withLDH>600 IU/L experienced an average hospital stay extension of 4.5 days,were 3.2 times more likely to require ICU admission, and faced a 12.1 times higher mortality risk compared to those with LDH <300 IU/L.Conclusion: This study highlights LDH as a potentially valuable predictor of hospital stay duration, ICU requirements, and mortality rates in AP patients. Its cost-effectiveness and accessibility suggest LDH testing could aid clinical decision-making in AP management. Future prospective studies should further explore LDH's role in optimizing AP patient care.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"15 1","pages":"8-12"},"PeriodicalIF":0.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin Therapy for Acute Pancreatitis in a Patient With Lipase Maturation Factor 1 Mutation: A Case Report.

IF 0.9

Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1431

Neha Bhaskar, Aram Bejnood, Christopher D Jackson

引用次数: 0

Severe Hypercalcemia Following Hip Joint Implantation of Calcium Sulfate Antibiotic Beads: Case Series and Review of Literature. 髋关节植入硫酸钙抗生素珠后的严重高钙血症：病例系列和文献综述。

IF 0.9

Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1449

Andrew P Demidowich, Mahsa Motevalli, Kevin Yi, Atena Kamali, Kristine Batty, Kendall F Moseley, Robert R Buber, Mehdi Hashemipour, Mihail Zilbermint

{"title":"Severe Hypercalcemia Following Hip Joint Implantation of Calcium Sulfate Antibiotic Beads: Case Series and Review of Literature.","authors":"Andrew P Demidowich, Mahsa Motevalli, Kevin Yi, Atena Kamali, Kristine Batty, Kendall F Moseley, Robert R Buber, Mehdi Hashemipour, Mihail Zilbermint","doi":"10.55729/2000-9666.1449","DOIUrl":"10.55729/2000-9666.1449","url":null,"abstract":"Purpose: The diagnosis and management of hypercalcemia in hospitalized patients can be challenging. Hypercalcemia is often associated with significant morbidity and end-organ damage which may delay a patient's recovery.Methods: We report a case series of three patients who underwent orthopedic procedures with intraoperative placement of vancomycin-loaded calcium sulfate beads. Patients had no known history of malignancy or excess intake of calcium, vitamin A or vitamin D. Laboratory workup showed low parathyroid (PTH) levels and normal PTH-related peptide levels. The temporal nature of the non-PTH mediated hypercalcemia in relation to implantation of the antibiotic beads suggests causality of exogenous calcium sulfate with the patients' subsequent hypercalcemia.Results: Patients were treated with aggressive intravenous saline and zoledronic acid resulting in resolution of hypercalcemia in all cases. The antibiotic impregnated beads did not require explantation.Conclusion: Hypercalcemia following calcium sulfate antibiotic bead implantation may contribute to patient morbidity and increased length-of-stay. We recommend serum calcium and creatinine be closely monitored during the early postoperative period in patients who receive calcium sulfate antibiotic beads.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"15 1","pages":"107-110"},"PeriodicalIF":0.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Whip-it Beyond Desserts: Causing Subacute Combined Degeneration - Case Report and Literature Review.

IF 0.9

Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1450

Vijayalakshmi Brahmashettar, Elton Ahadov, Tamilla Rzayeva, Westley T Hartley, Nargiz Muganlinskaya

{"title":"Whip-it Beyond Desserts: Causing Subacute Combined Degeneration - Case Report and Literature Review.","authors":"Vijayalakshmi Brahmashettar, Elton Ahadov, Tamilla Rzayeva, Westley T Hartley, Nargiz Muganlinskaya","doi":"10.55729/2000-9666.1450","DOIUrl":"10.55729/2000-9666.1450","url":null,"abstract":"Nitrous oxide (N2O) has been increasingly used for recreational purposes due to its dissociative and euphoric properties. Exposure to N2O results in the deactivation of in vivo vitamin B12, leading to subsequent neurological sequelae due to vitamin B12 deficiency.7 Current management focuses on cessation of exposure and replacement therapy, yet patients may continue to suffer from permanent neurological damage.12 We report a case of a 50-year-old woman who presented with impaired balance, a subacute decline in mental status, multiple falls, and back pain. She was hospitalized for evaluation of her presenting symptoms and for pain management. The patient's sister helped uncover the patient's misuse of N2O via \"Whip-it!\" cartridges. Physical examination, along with magnetic resonance imaging of the cervical and thoracic spine, confirmed the diagnosis of subacute combined degeneration (SCD), and appropriate treatment was initiated. Our case aims to bring attention to this seemingly harmless recreational drug that continues to regain popularity and its association with brain and nerve damage.13.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"15 1","pages":"111-114"},"PeriodicalIF":0.9,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gene Editing: Developments, Ethical Considerations, and Future Directions.

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2025-01-06 eCollection Date: 2025-01-01 DOI: 10.55729/2000-9666.1445

Manav C Parikh

引用次数: 0