Journal of Community Hospital Internal Medicine Perspectives最新文献_第4页

Dieulafoy's Lesion in the Esophagus Causing Gastrointestinal Bleeding: A Concise Review. 食道二甲磺酸钠病变引起胃肠道出血：简要回顾。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1425

Lefika Bathobakae, Joseph Russo, Devina Adalja, Malina Mohtadi, Tyler Wilkinson, Nader Mekheal, Ruhin Yuridullah, Kamal Amer, Yana Cavanagh, Walid Baddoura

{"title":"Dieulafoy's Lesion in the Esophagus Causing Gastrointestinal Bleeding: A Concise Review.","authors":"Lefika Bathobakae, Joseph Russo, Devina Adalja, Malina Mohtadi, Tyler Wilkinson, Nader Mekheal, Ruhin Yuridullah, Kamal Amer, Yana Cavanagh, Walid Baddoura","doi":"10.55729/2000-9666.1425","DOIUrl":"10.55729/2000-9666.1425","url":null,"abstract":"Dieulafoy's lesion (DL) is an uncommon cause of life-threatening gastrointestinal (GI) bleeding. It can occur in any part of the GI tract, including the stomach, duodenum, colon, and esophagus. Dieulafoy's lesion in the esophagus (DLE) is an exceedingly rare entity, with only 23 case reports/series (27 patients) reported to date. We performed a systematic search of published case reports on DLE in PubMed, Google Scholar, and Embase, from inception through January 2024. The search terms for the review were \"Dieulafoy's lesion,\" \"esophagus,\" \"oesophagus,\" \"hematemesis,\" \"melena,\" \"hematochezia,\" and \"gastrointestinal bleeding.\" Articles were eligible for inclusion in the study if they were published in English, described a case of DLE noted on endoscopy or histopathology, and were available as full text. Our literature search yielded 23 articles consisting of 27 patients. Of the 27 patients, eight (30%) were female and 19 (70%) were male. The patients' age ranged from 13 years to 87 years, with an average age of 54.1 years. Twenty-five patients (92.6%) presented with hematemesis and melena as chief complaints. DLE was found in the distal esophagus in 19/27 (70.4%) of the patients and the mid-esophagus in 6/27 (22.2%) of the patients. Two patients had no information about the lesion site. Endoscopic hemoclips were employed in 12 (44.4%) patients, endoscopic band ligation (EBL) in six and electrocautery was used in one patient. Early diagnosis and prompt treatment are crucial for managing DLE, as they can cause recurrent bleeding and potentially lead to complications or death.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"14 6","pages":"82-88"},"PeriodicalIF":0.9,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lymphocytic Gastritis in a Patient With Microscopic Colitis: A Case Report. 淋巴细胞性胃炎合并显微镜下结肠炎1例。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1421

Saba Ahmed, Jewel Estrella, Khaleeq Siddiqui, Fahad Malik, Karen Avgush, Yasir Ahmed

引用次数: 0

Outcomes of Low Barrier Hepatitis C Treatment in High Risk Populations From Primary Care. 初级保健对高危人群低屏障丙型肝炎治疗的效果

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1404

Scarlett Austin, Kristi Seemiller, Brittany Nolton, Emily Hobart, Bruce Ling, Jonathan Ghobrial, Thomas Robertson

{"title":"Outcomes of Low Barrier Hepatitis C Treatment in High Risk Populations From Primary Care.","authors":"Scarlett Austin, Kristi Seemiller, Brittany Nolton, Emily Hobart, Bruce Ling, Jonathan Ghobrial, Thomas Robertson","doi":"10.55729/2000-9666.1404","DOIUrl":"10.55729/2000-9666.1404","url":null,"abstract":"Hepatitis C (HCV) can be treated in the primary care setting; however, most patients are referred to subspecialists. Marginalized populations may be refused treatment due to stigma or substance use. We aimed to treat HCV in these high-risk patients, and prevent a delay in time from diagnosis to the time of treatment and sustained virologic response (SVR), by utilizing a multidisciplinary treatment team in a primary care clinic. Outcomes assessed included achieving SVR at 3 months, time from diagnosis to treatment initiation, and liver fibrosis stage compared between cohorts with previous subspecialty referral and those treated initially from primary care. Among the 32 patients who initiated treatment, 29 (90.6%) completed the regimen and 27 (84.3%) had documented SVR. Patients treated in a primary care setting without prior referral had a significantly shorter median time from viral load testing to treatment initiation (161 days), compared to those who were previously referred (median time of 954 days). Aggregated fibrosis scores suggest those referred to subspecialists had significantly higher scores. We demonstrate successful HCV treatment in primary care achieving SVR, and a decrease in the median days between viral load and treatment initiation, with lower fibrosis scores.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"14 6","pages":"10-17"},"PeriodicalIF":0.9,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sevelamer-induced Gastrointestinal Mucosal Injury: A Critical Review for Clinicians. sevelmer诱导的胃肠道粘膜损伤：临床医生的重要回顾。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1424

Lefika Bathobakae, Phenyo Phuu, Saif Yasin, Rammy Bashir, Jessica Escobar, Ruhin Yuridullah, Gabriel Melki, Mohamed Elagami, Kamal Amer, Yana Cavanagh, Walid Baddoura

{"title":"Sevelamer-induced Gastrointestinal Mucosal Injury: A Critical Review for Clinicians.","authors":"Lefika Bathobakae, Phenyo Phuu, Saif Yasin, Rammy Bashir, Jessica Escobar, Ruhin Yuridullah, Gabriel Melki, Mohamed Elagami, Kamal Amer, Yana Cavanagh, Walid Baddoura","doi":"10.55729/2000-9666.1424","DOIUrl":"10.55729/2000-9666.1424","url":null,"abstract":"Sevelamer is a non-absorbable polymer used to treat hyperphosphatemia in individuals with end-stage renal disease (ESRD) undergoing hemodialysis. The deposition of sevelamer crystals in the gastrointestinal (GI) tract, especially in the colon, can cause mucosal inflammation, pseudopolyps, ulceration, ischemia, or necrosis. Owing to its rarity and lack of physician awareness, the actual incidence and prevalence of sevelamer-induced gastrointestinal mucosal injury (SIGMI) remain unknown. The current evidence is retrospective, in the form of observational studies. This systematic review of case reports provides an overview of SIGMI, with a focus on its etiology, signs and symptoms, pathogenesis, diagnosis, and management. Electronic databases, including PubMed, Embase, and Google Scholar, were searched for published case reports, case series, and abstracts from inception to August 2023. The search yielded 1239 articles that were filtered using the study design, English language, and human subjects. After screening for duplicates and irrelevant articles, only 28 articles were included in the final review. Melena and abdominal pain were the most common complaints. Sevelamer was discontinued in all patients, and 27 (75%) experienced clinical improvement or symptom resolution. Eight patients (22%) required colectomy due to colonic perforation, malignant obstruction, or extensive necrosis. SIGMI is a unique complication of sevelamer use in patients undergoing hemodialysis. Prompt diagnosis and management are crucial to prevent life-threatening complications.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"14 6","pages":"58-65"},"PeriodicalIF":0.9,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuropsychiatric Manifestations of Syphilis. 梅毒的神经精神表现。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1416

Nadim Ojaimi, Aida Metri, Christopher J Haas

引用次数: 0

Atypical Thyroid Stimulating Hormone Levels in Myxedema Coma Complicated by Severe Sepsis. 黏液水肿昏迷并发严重脓毒症的非典型促甲状腺激素水平。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1412

Nazmul Hasan, Daniel Yang, Thaer Othman, Jenny Dai-Ju

引用次数: 0

Role of Artificial Intelligence-assisted Decision Support Tool for Common Rhythm Disturbances: A ChatGPT Proof-of-concept Study. 人工智能辅助决策支持工具在常见节律干扰中的作用：一项ChatGPT概念验证研究。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1402

Jahanzeb Malik, Muhammad W Afzal, Salaar S Khan, Muhammad R Umer, Bushra Fakhar, Amin Mehmoodi

{"title":"Role of Artificial Intelligence-assisted Decision Support Tool for Common Rhythm Disturbances: A ChatGPT Proof-of-concept Study.","authors":"Jahanzeb Malik, Muhammad W Afzal, Salaar S Khan, Muhammad R Umer, Bushra Fakhar, Amin Mehmoodi","doi":"10.55729/2000-9666.1402","DOIUrl":"10.55729/2000-9666.1402","url":null,"abstract":"Background: The objective of this article was to explore the use of ChatGPT as a clinical support tool for common arrhythmias.Methods: This study assessed the feasibility of using ChatGPT as an AI decision-support tool for common rhythm disturbances. The study was conducted using retrospective data collected from electronic medical records (EMRs) of patients with documented rhythm disturbances. The model's performance was evaluated using sensitivity, specificity, positive predictive value, and negative predictive value.Results: A total of 20,000 patients with rhythm disturbances were included in the study. The ChatGPT model demonstrated high diagnostic accuracy in identifying and diagnosing common rhythm disturbances, with a sensitivity of 93%, specificity of 89%, positive predictive value of 91%, and negative predictive value of 92%. The ROC curve analysis showed an area under the curve (AUC) of 0.743, indicating the excellent diagnostic performance of the ChatGPT model.Conclusion: The model's diagnostic performance was comparable to clinical experts, indicating its potential to enhance clinical decision-making and improve patient outcomes.Clinical trial registration: Not applicable.","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"14 6","pages":"5-9"},"PeriodicalIF":0.9,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cough-hypersensitivity Syndrome-A New Paradigm in the Evaluation of Chronic Refractory Cough and Its Novel Therapeutic Horizons-A Review. 咳嗽-超敏综合征——慢性难治性咳嗽评价的新范式及其新的治疗前景综述

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1417

Dawlat Khan, Hammad Chaudhry, Phool Iqbal, Dawood Shehzad, Muhammad Yasir, Wahab Khan, Aiman Zia, Mamoon Ahmed

{"title":"Cough-hypersensitivity Syndrome-A New Paradigm in the Evaluation of Chronic Refractory Cough and Its Novel Therapeutic Horizons-A Review.","authors":"Dawlat Khan, Hammad Chaudhry, Phool Iqbal, Dawood Shehzad, Muhammad Yasir, Wahab Khan, Aiman Zia, Mamoon Ahmed","doi":"10.55729/2000-9666.1417","DOIUrl":"10.55729/2000-9666.1417","url":null,"abstract":"Chronic cough is defined as a persistent cough, lasting beyond 8 weeks, poses a global health challenge, impacting a substantial portion of the world's population. In the United States, it stands as a prominent cause for numerous visits to primary care and pulmonology clinics, imposing a significant healthcare burden and utilizing valuable resources. While chronic cough can be indicative of serious underlying lung conditions, once serious pulmonary diseases are excluded, the leading culprits are often identified as gastroesophageal reflux, upper airway cough syndrome, and eosinophilic airway inflammation. Cough Hypersensitivity Syndrome (CHS) serves as a paradigm for understanding chronic refractory cough. CHS is chronic cough triggered by low-level tussigneic stimuli once more common etiologies have been effectively addressed. This review delves into the definition, pathophysiology, current therapeutic options, and novel treatments for Cough Hypersensitivity Syndrome (CHS).","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"14 6","pages":"75-81"},"PeriodicalIF":0.9,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143006399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hidradenitis Suppurativa and Peripheral Ulcerative Keratitis. 化脓性和周围性溃疡性角膜炎。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1408

Indira Acharya, Mohamed I Jalloh, Caroline D Trevisan, Christopher J Haas

引用次数: 0

A Rare Case of Anti-Caspr2 Autoimmune Encephalitis Associated with a Testicular Mixed Germ Cell Tumor. 罕见的抗caspr2自身免疫性脑炎合并睾丸混合生殖细胞瘤1例。

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Journal of Community Hospital Internal Medicine Perspectives Pub Date : 2024-11-02 eCollection Date: 2024-01-01 DOI: 10.55729/2000-9666.1414

Rakahn Haddadin, Danny Aboujamra, Kush Kapadia, Samuel Yoon, Zade Zahlan, Lindsay Buczek, Hatim Gemil

引用次数: 0