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Journal of Asian Natural Products Research最新文献

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Three new coumarins from Notopterygium incisum with potential anti-inflammatory activity 具有潜在抗炎活性的 Notopterygium incisum 中的三种新香豆素。
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2411704
Xue-Yan Huo , Meng-Dan Liu , Yu-Hui Chen , Yun-Jie Hu , Chen-Yi Yan , Da-Le Guo , Yu-Cheng Gu , Li-Jun Huang , Yun Deng
{"title":"Three new coumarins from Notopterygium incisum with potential anti-inflammatory activity","authors":"Xue-Yan Huo ,&nbsp;Meng-Dan Liu ,&nbsp;Yu-Hui Chen ,&nbsp;Yun-Jie Hu ,&nbsp;Chen-Yi Yan ,&nbsp;Da-Le Guo ,&nbsp;Yu-Cheng Gu ,&nbsp;Li-Jun Huang ,&nbsp;Yun Deng","doi":"10.1080/10286020.2024.2411704","DOIUrl":"10.1080/10286020.2024.2411704","url":null,"abstract":"<div><div>Three previously undescribed coumarins (<strong>1</strong>–<strong>3</strong>) were obtained from the roots of <em>Notopterygium incisum</em>. Their chemical structures were elucidated using a variety of spectroscopic techniques and chemical calculations. The inhibitory effects of these new compounds on NO production and pro-inflammatory factors (<em>IL-1β</em>, <em>IL-6</em>, and <em>TNF-α</em>) in LPS-stimulated RAW 264.7 cells were investigated. Further studies revealed that compound <strong>1</strong> suppressed the expression of COX-2 and iNOS while also reduced ROS accumulation. Western blot analysis demonstrated that compound <strong>1</strong> could inhibit the PI3K/AKT pathway by decreasing the levels of p-PI3K and p-AKT. Collectively, these findings suggest that compounds <strong>1</strong>–<strong>3</strong> exhibit promising anti-inflammatory properties.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 18-30"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare prenylated isoflavone-quinone from the roots of Flemingia philippinensis 从菲律宾佛兰芒根中提取的一种罕见的前酰化异黄酮醌。
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2421918
Sheng-Li Niu , Xiao-Zhuo Han , Yan-Ping Wang , Jia-Hui Hao , Fei Mo , Can-Can Cui , Ying-Yu Wang , Lu-Yao Zhang , Ya-Ting Sun
{"title":"A rare prenylated isoflavone-quinone from the roots of Flemingia philippinensis","authors":"Sheng-Li Niu ,&nbsp;Xiao-Zhuo Han ,&nbsp;Yan-Ping Wang ,&nbsp;Jia-Hui Hao ,&nbsp;Fei Mo ,&nbsp;Can-Can Cui ,&nbsp;Ying-Yu Wang ,&nbsp;Lu-Yao Zhang ,&nbsp;Ya-Ting Sun","doi":"10.1080/10286020.2024.2421918","DOIUrl":"10.1080/10286020.2024.2421918","url":null,"abstract":"<div><div>In order to make more rational use of <em>Flemingia Philippinensis</em>, a systematic separation from the roots of <em>F. philippinensis</em> was performed in the current study. The investigation of chemical constituents resulted in the isolation of a rare prenylated isoflavone-quinone, fleminquinone A (<strong>1</strong>), together with four known analogues (<strong>2–5</strong>). Their structures were established by extensive physical and spectroscopic data analysis. Anti-inflammatory activities of the isolated compounds were evaluated in lipopolysaccharide induced mouse mononuclear macrophage leukemia cells RAW 264.7 model. Compound <strong>1</strong> exhibited significant inhibitory effects on LPS-induced NO production and COX-2. Compound <strong>1</strong> also significantly affected the levels of inflammatory cytokines.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 98-105"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Five anti-inflammatory compounds from the resins of Liquidambar orientalis 东方枫香树树脂中的五种抗炎化合物
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2379978
Hao Chen , Sheng-Hong Li , Yong-Xian Cheng
{"title":"Five anti-inflammatory compounds from the resins of Liquidambar orientalis","authors":"Hao Chen ,&nbsp;Sheng-Hong Li ,&nbsp;Yong-Xian Cheng","doi":"10.1080/10286020.2024.2379978","DOIUrl":"10.1080/10286020.2024.2379978","url":null,"abstract":"<div><div>Five undescribed compounds, including a triterpenoid (<strong>1</strong>), three phenylpropanoids [(±)−<strong>2</strong> and <strong>4</strong>], and an aromatic compound (<strong>3</strong>), as well as six known analogues (<strong>5</strong>–<strong>10</strong>), were isolated from the resins of <em>Liquidambar orientalis</em> Mill. Their structures, including absolute configurations, were determined by using spectroscopic and computational methods, and the five new compounds displayed anti-inflammatory activities in LPS-induced RAW264.7 cells.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 1-10"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141774688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral health promotion of flavonoids from Scutellaria baicalensis 黄芩中的黄酮类化合物对口腔健康的促进作用
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2428797
Bai-Xiang Cai , Qing-Yang Wu , Jin-Lian Huang , Jing Wu , Yang Yu , Lei Xiao , Xiang-Hai Cai
{"title":"Oral health promotion of flavonoids from Scutellaria baicalensis","authors":"Bai-Xiang Cai ,&nbsp;Qing-Yang Wu ,&nbsp;Jin-Lian Huang ,&nbsp;Jing Wu ,&nbsp;Yang Yu ,&nbsp;Lei Xiao ,&nbsp;Xiang-Hai Cai","doi":"10.1080/10286020.2024.2428797","DOIUrl":"10.1080/10286020.2024.2428797","url":null,"abstract":"<div><div>Looking for materials from <em>Scutellaria baicalensis</em> to improve oral inflammation and eliminate bad breath led to one new compound, 5,7,2′,5′-tetrahydroxy-6′-methoxyflavone (<strong>1</strong>) and 32 known ones. Among of them, 3 flavones (<strong>11</strong>, <strong>17</strong>, <strong>18</strong>), 2 dihydroflavones (<strong>23</strong>, <strong>25</strong>), 2 flavone glucosides (<strong>30</strong>, <strong>32</strong>), and a chalcone (<strong>26</strong>) could inhibit oral anaerobic bacteria <em>Fusobacterium nucleatum</em>, <em>Streptococcus mutans</em>, and <em>Porphyromonas gingivalis</em>. Compounds <strong>3, 14</strong>, <strong>18</strong> could inhibit oral bacterial <em>Staphylococcus aureus</em>. Compounds <strong>5</strong>, <strong>8</strong>, <strong>13</strong> and <strong>21</strong> exhibited strong inhibitory NO production. Additionally, <strong>14</strong> and <strong>26</strong> showed good COX-1/2 inhibitory effects. These results indicated <em>S. baicalensis</em> has potential oral health benefits.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 88-97"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142716182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fuzheng Huayu recipe inhibits bleomycin-induced pulmonary fibrosis in rats by inhibiting M2 polarization of macrophages via the oxidative phosphorylation pathway 扶正化瘀方通过氧化磷酸化途径抑制巨噬细胞的M2极化，从而抑制博莱霉素诱导的大鼠肺纤维化。
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2371050
Xing-Hua Yuan , Su-Fang Zhang , Yu Hang , Yan-Hua Shen , Shan-Fang Zhang , Wei-Ling Huang , Jing-Yi Huang , Ye-Chang Qian , Xiu-Lian Zhang , Qiu-Hong Li , Li Li
{"title":"Fuzheng Huayu recipe inhibits bleomycin-induced pulmonary fibrosis in rats by inhibiting M2 polarization of macrophages via the oxidative phosphorylation pathway","authors":"Xing-Hua Yuan ,&nbsp;Su-Fang Zhang ,&nbsp;Yu Hang ,&nbsp;Yan-Hua Shen ,&nbsp;Shan-Fang Zhang ,&nbsp;Wei-Ling Huang ,&nbsp;Jing-Yi Huang ,&nbsp;Ye-Chang Qian ,&nbsp;Xiu-Lian Zhang ,&nbsp;Qiu-Hong Li ,&nbsp;Li Li","doi":"10.1080/10286020.2024.2371050","DOIUrl":"10.1080/10286020.2024.2371050","url":null,"abstract":"<div><div>Fuzheng Huayu recipe (FZHYR) is a Chinese patent medicine for the treatment of fibrosis. The effects of FZHYR on pulmonary fibrosis and macrophage polarization were investigated <em>in vitro</em>. FZHYR inhibited pulmonary inflammation and fibrosis and M2 polarization of macrophages in bleomycin-induced pulmonary fibrosis (BPF) of rat model. Differentially expressed genes were screened by high-throughput mRNA sequencing and GSEA showed that oxidative phosphorylation (OXPHOS) was correlated with BPF. FZHYR inhibited expressions of <em>Ndufa2</em> and <em>Ndufa6</em> in lung tissues of BPF rats. These findings suggest that OXPHOS pathway serves as a possible target for pulmonary fibrosis therapy by FZHYR.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 62-74"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoterpene indole glycoalkaloids from the hook-bearing branches of Uncaria rhynchophylla 钩藤含钩枝中的单萜吲哚甘氨酰生物碱。
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2410460
Lu Rao , Fei Chen , Ming-Hui Gao , Jun-Jie Tan , Shi-Jin Qu , Chang-Heng Tan
{"title":"Monoterpene indole glycoalkaloids from the hook-bearing branches of Uncaria rhynchophylla","authors":"Lu Rao ,&nbsp;Fei Chen ,&nbsp;Ming-Hui Gao ,&nbsp;Jun-Jie Tan ,&nbsp;Shi-Jin Qu ,&nbsp;Chang-Heng Tan","doi":"10.1080/10286020.2024.2410460","DOIUrl":"10.1080/10286020.2024.2410460","url":null,"abstract":"<div><div>Twelve monoterpene indole glycoalkaloids, comprising of three new ones, 19-<em>epi</em>-rhynchophylloside A (<strong>1</strong>), 7-<em>epi</em>-rhynchophylloside A (<strong>2</strong>), and 7-<em>epi</em>-anthocephalusine A (<strong>3</strong>), were isolated from the hook-bearing branches of <em>Uncaria rhynchophylla</em>. The structures and absolute configurations of <strong>1–3</strong> were elucidated by analysis of MS, NMR, ECD, and single-crystal X-ray diffraction or TDDFT-ECD calculations. Glycoalkaloids <strong>1</strong> and <strong>3</strong> showed significant immunosuppressive activity against the proliferation of B lymphocyte induced by LPS with broad selective index.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 31-37"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Harmine inhibits the proliferation and migration and promotes the apoptosis of colon cancer cells via inhibition of the FAK/AKT and ERK1/2/CREB signaling pathways Harmine 通过抑制 FAK/AKT 和 ERK1/2/CREB 信号通路，抑制结肠癌细胞的增殖和迁移，并促进其凋亡。
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2361767
Fu-Hong Liu , Xing-Cheng Lin , Yu-Wei Liu , Tian-Tian Zhang , Yang-Bo Zhang , Zhuo-Long Xie , Yuan Zhan , Ping Hu
{"title":"Harmine inhibits the proliferation and migration and promotes the apoptosis of colon cancer cells via inhibition of the FAK/AKT and ERK1/2/CREB signaling pathways","authors":"Fu-Hong Liu ,&nbsp;Xing-Cheng Lin ,&nbsp;Yu-Wei Liu ,&nbsp;Tian-Tian Zhang ,&nbsp;Yang-Bo Zhang ,&nbsp;Zhuo-Long Xie ,&nbsp;Yuan Zhan ,&nbsp;Ping Hu","doi":"10.1080/10286020.2024.2361767","DOIUrl":"10.1080/10286020.2024.2361767","url":null,"abstract":"<div><div>Harmine is present in a variety of medicinal plants, and its effects on colon cancer cells remain unclear. Here, we found that harmine exhibited significant inhibitory effects on the proliferation of colon cancer cells by inhibiting the phosphorylation levels of the FAK/AKT and ERK1/2/CREB. Furthermore, harmine also inhibited the migration of colon cancer cells and suppressed the expression levels of MMP-2, MMP-9, and VEGF. Additionally, harmine-induced apoptosis in colon cancer cells by regulating the expression of Bcl-2 and Bax. In conclusion, our findings suggest that harmine exerts a significant inhibitory effect on the development of colon cancer cells.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 75-87"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three new cyclopentanoid monoterpenes from the roots of Picrorhiza scrophulariiflora 来自 Picrorhiza scrophulariiflora 根部的三种新的环戊烷单萜烯。
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2408547
Xin-Yue Li , Jie Zhou , Guo-Ru Shi , Wan-Qi Zhang , Ming-Hui Sun , Jing-Han Zhang , Xin-Li Ma , Gu Zhao , Yan-Fei Liu , De-Quan Yu
{"title":"Three new cyclopentanoid monoterpenes from the roots of Picrorhiza scrophulariiflora","authors":"Xin-Yue Li ,&nbsp;Jie Zhou ,&nbsp;Guo-Ru Shi ,&nbsp;Wan-Qi Zhang ,&nbsp;Ming-Hui Sun ,&nbsp;Jing-Han Zhang ,&nbsp;Xin-Li Ma ,&nbsp;Gu Zhao ,&nbsp;Yan-Fei Liu ,&nbsp;De-Quan Yu","doi":"10.1080/10286020.2024.2408547","DOIUrl":"10.1080/10286020.2024.2408547","url":null,"abstract":"<div><div>Three new cyclopentanoid monoterpenes, neopiscrocins A–C (<strong>1</strong>–<strong>3</strong>), together with 14 known compounds (<strong>4</strong>–<strong>17</strong>), were isolated from the roots of <em>Picrorhiza scrophulariiflora</em>. The structres of these compounds were elucidated on the basis of their spectroscopic data. All compounds were evaluated for cytotoxicity against six human tumor cell lines (PC9, PANC1, HCT-116, Hep-G2, BGC-823, and MCF-7), hepatoprotective activity and anti-inflammatory activity.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 38-46"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142347316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bis-piperidine alkaloids from the peels of Areca catechu 从Areca catechu果皮中提取的双哌啶生物碱。
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2372383
Xia Zhang , Fang-Xin Wang , Zi-Wei Li , Song Wang , Shi-Qing Zhang , Min Song , Xiao-Qi Zhang
{"title":"Bis-piperidine alkaloids from the peels of Areca catechu","authors":"Xia Zhang ,&nbsp;Fang-Xin Wang ,&nbsp;Zi-Wei Li ,&nbsp;Song Wang ,&nbsp;Shi-Qing Zhang ,&nbsp;Min Song ,&nbsp;Xiao-Qi Zhang","doi":"10.1080/10286020.2024.2372383","DOIUrl":"10.1080/10286020.2024.2372383","url":null,"abstract":"<div><div>Four new alkaloids, arecatines A–D (<strong>1</strong>–<strong>4</strong>), were isolated from the peels of <em>Areca catechu</em>. Compound <strong>1</strong> is an unusual piperidine-pyridine hybrid alkaloid, whereas compounds <strong>2</strong>–<strong>4</strong> feature bis-piperidine alkaloids. Their structures were elucidated by UV, IR, HRESIMS, and NMR spectra analysis. The molecular docking analysis indicated that compound <strong>3</strong> exhibited the best binding affinity with the GABA<sub>A</sub> receptor, indicating its potential anti-epilepsy activity.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 11-17"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Online identification of chemical constituents in Mongolian medicine Zhachong-13 pills by UHPLC-Q-exactive Orbitrap MS 超高效液相色谱-Q-反应式 Orbitrap MS 在线鉴定蒙药扎冲十三味丸中的化学成分
IF 1.3 3区 医学
Journal of Asian Natural Products Research Pub Date : 2025-01-02 DOI: 10.1080/10286020.2024.2379981
Cai-Yun Tian , Qing-Rui Yang , Ling-Xuan Fan , Yu-Mei Yang , Bo-Wen Gao , Jian-Bo Yang
{"title":"Online identification of chemical constituents in Mongolian medicine Zhachong-13 pills by UHPLC-Q-exactive Orbitrap MS","authors":"Cai-Yun Tian ,&nbsp;Qing-Rui Yang ,&nbsp;Ling-Xuan Fan ,&nbsp;Yu-Mei Yang ,&nbsp;Bo-Wen Gao ,&nbsp;Jian-Bo Yang","doi":"10.1080/10286020.2024.2379981","DOIUrl":"10.1080/10286020.2024.2379981","url":null,"abstract":"<div><div>Zhachong-13 pills (ZC-13), as a traditional prescription of Mongolian medicine, are often used in the clinical practice of Mongolian hospitals for the treatment of stroke and rheumatic arthritis. In this experiment, UHPLC-Q-Exactive Orbitrap MS was used to explore the chemical composition of ZC-13. The results showed that 315 compounds were identified or inferred, including 56 alkaloids, 77 2-(2-phenylethyl)chromones, 61 flavonoids, 31 tannins, 8 coumarins, 16 lignans, 21 terpenoids, 5 amino acids, 19 organic acids, and 21 other components. In addition, the pharmacological activities related to anti-cerebral ischemia of these components were summarized. This result laid a foundation for further study on the pharmacodynamic material basis of ZC-13 and provided a scientific basis for the formulation of ZC-13 quality specifications.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"27 1","pages":"Pages 47-61"},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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