Frontiers in Neuroendocrinology最新文献_第4页

The role of stress in perinatal depression and anxiety – A systematic review 压力在围产期抑郁和焦虑中的作用 - 系统综述

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2024-01-01 DOI: 10.1016/j.yfrne.2023.101117

MA. Schalla , A. Stengel

引用次数: 0

Electroencephalography findings in menstrually-related mood disorders: A critical review 月经相关情绪障碍的脑电图检查结果：批判性评论

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2024-01-01 DOI: 10.1016/j.yfrne.2023.101120

Elisavet Kaltsouni , Felix Schmidt , Rachel G. Zsido , Allison Eriksson , Julia Sacher , Inger Sundström-Poromaa , Rachael L. Sumner , Erika Comasco

{"title":"Electroencephalography findings in menstrually-related mood disorders: A critical review","authors":"Elisavet Kaltsouni , Felix Schmidt , Rachel G. Zsido , Allison Eriksson , Julia Sacher , Inger Sundström-Poromaa , Rachael L. Sumner , Erika Comasco","doi":"10.1016/j.yfrne.2023.101120","DOIUrl":"10.1016/j.yfrne.2023.101120","url":null,"abstract":"<div><p>The female reproductive years are characterized by fluctuations in ovarian hormones across the menstrual cycle, which have the potential to modulate neurophysiological and behavioral dynamics. Menstrually-related mood disorders (MRMDs) comprise cognitive-affective or somatic symptoms that are thought to be triggered by the rapid fluctuations in ovarian hormones in the luteal phase of the menstrual cycle. MRMDs include premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and premenstrual exacerbation (PME) of other psychiatric disorders. Electroencephalography (EEG) non-invasively records <em>in vivo</em> synchronous activity from populations of neurons with high temporal resolution. The present overview sought to systematically review the current state of task-related and resting-state EEG investigations on MRMDs. Preliminary evidence indicates lower alpha asymmetry at rest being associated with MRMDs, while one study points to the effect being luteal-phase specific. Moreover, higher luteal spontaneous frontal brain activity (slow/fast wave ratio as measured by the delta/beta power ratio) has been observed in persons with MRMDs, while sleep architecture results point to potential circadian rhythm disturbances. In this review, we discuss the quality of study designs as well as future perspectives and challenges of supplementing the diagnostic and scientific toolbox for MRMDs with EEG.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"72 ","pages":"Article 101120"},"PeriodicalIF":7.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302223000687/pdfft?md5=7d42373733a3221ea792628ecfc63b05&pid=1-s2.0-S0091302223000687-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139084483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Modulatory role of neurosteroidogenesis in the spinal cord during peripheral nerve injury-induced chronic pain 周围神经损伤诱发慢性疼痛期间脊髓中神经类固醇生成的调节作用

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2024-01-01 DOI: 10.1016/j.yfrne.2023.101116

Ayikoe-Guy Mensah-Nyagan, Laurence Meyer , Christine Patte-Mensah

{"title":"Modulatory role of neurosteroidogenesis in the spinal cord during peripheral nerve injury-induced chronic pain","authors":"Ayikoe-Guy Mensah-Nyagan, Laurence Meyer , Christine Patte-Mensah","doi":"10.1016/j.yfrne.2023.101116","DOIUrl":"10.1016/j.yfrne.2023.101116","url":null,"abstract":"<div><p>The brain and spinal cord (SC) are both targeted by various hormones, including steroid hormones. However, investigations of the modulatory role of hormones on neurobiological functions usually focus only on the brain. The SC received little attention although this structure pivotally controls motor and sensory functions. Here, we critically reviewed key data showing that the process of neurosteroid biosynthesis or neurosteroidogenesis occurring in the SC plays a pivotal role in the modulation of peripheral nerve injury-induced chronic pain (PNICP) or neuropathic pain. Indeed, several active steroidogenic enzymes expressed in the SC produce endogenous neurosteroids that interact with receptors of neurotransmitters controlling pain. The spinal neurosteroidogenesis is differentially regulated during PNICP condition and its blockade modifies painful sensations. The paper suggests that future investigations aiming to develop effective strategies against PNICP or neuropathic pain must integrate in a gender or sex dependent manner the regulatory effects exerted by spinal neurosteroidogenesis.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"72 ","pages":"Article 101116"},"PeriodicalIF":7.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139093971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-Finasteride Syndrome And Post-Ssri Sexual Dysfunction: Two Clinical Conditions Apparently Distant, But Very Close 非那雄胺后综合征和ssri后性功能障碍:两种临床症状，表面上相距遥远，但非常接近。

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2023-11-21 DOI: 10.1016/j.yfrne.2023.101114

Silvia Giatti, Silvia Diviccaro, Lucia Cioffi, Roberto Cosimo Melcangi

{"title":"Post-Finasteride Syndrome And Post-Ssri Sexual Dysfunction: Two Clinical Conditions Apparently Distant, But Very Close","authors":"Silvia Giatti, Silvia Diviccaro, Lucia Cioffi, Roberto Cosimo Melcangi","doi":"10.1016/j.yfrne.2023.101114","DOIUrl":"10.1016/j.yfrne.2023.101114","url":null,"abstract":"<div><p>Post-finasteride syndrome and post-SSRI sexual dysfunction, are two poorly explored clinical conditions in which men treated for androgenetic alopecia with finasteride or for depression with SSRI antidepressants show persistent side effects despite drug suspension (e.g., sexual dysfunction, psychological complaints, sleep disorders). Because of some similarities in the symptoms, common pathological mechanisms are proposed here. Indeed, as discussed, clinical studies and preclinical data obtained so far suggest an important role for brain modulators (i.e., neuroactive steroids), neurotransmitters (i.e., serotonin, and cathecolamines), and gut microbiota in the context of the gut-brain axis. In particular, the observed interconnections of these signals in these two clinical conditions may suggest similar etiopathogenetic mechanisms, such as the involvement of the enzyme converting norepinephrine into epinephrine (i.e., phenylethanolamine N-methyltransferase). However, despite the current efforts, more work is still needed to advance the understanding of these clinical conditions in terms of diagnostic markers and therapeutic strategies.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"72 ","pages":"Article 101114"},"PeriodicalIF":7.4,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302223000626/pdfft?md5=5141fc97c04f150685f7fd47f184422c&pid=1-s2.0-S0091302223000626-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138295045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex differences in bipolar disorder: The dorsolateral prefrontal cortex as an etiopathogenic region 双相情感障碍的性别差异:背外侧前额皮质作为一个致病区域。

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2023-11-21 DOI: 10.1016/j.yfrne.2023.101115

Lin Zhang, Dick F. Swaab

{"title":"Sex differences in bipolar disorder: The dorsolateral prefrontal cortex as an etiopathogenic region","authors":"Lin Zhang, Dick F. Swaab","doi":"10.1016/j.yfrne.2023.101115","DOIUrl":"10.1016/j.yfrne.2023.101115","url":null,"abstract":"<div><p>Bipolar disorder (BD) is worldwide a prevalent mental illness and a leading risk factor for suicide. Over the past three decades, it has been discovered that sex differences exist throughout the entire panorama of BD, but the etiologic regions and mechanisms that generate such differences remain poorly characterized. Available evidence indicates that the dorsolateral prefrontal cortex (DLPFC), a critical region that controls higher-order cognitive processing and mood, exhibits biological disparities between male and female patients with psychiatric disorders, which are highly correlated with the co-occurrence of psychotic symptoms. This review addresses the sex differences in BD concerning epidemiology, cognitive impairments, clinical manifestations, neuroimaging, and laboratory abnormalities. It also provides strong evidence linking DLPFC to the etiopathogenesis of these sex differences. We emphasize the importance of identifying gene signatures using human brain transcriptomics, which can depict sexually different variations, explain sex-biased symptomatic features, and provide novel targets for sex-specific therapeutics.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"72 ","pages":"Article 101115"},"PeriodicalIF":7.4,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302223000638/pdfft?md5=9f44c076cbcf28d04856a5f139b0fae2&pid=1-s2.0-S0091302223000638-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138295046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in steroid research from the pioneering neurosteroid concept to metabolomics: New insights into pregnenolone function 从开创性的神经类固醇概念到代谢组学的类固醇研究进展:对孕烯醇酮功能的新见解。

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2023-11-21 DOI: 10.1016/j.yfrne.2023.101113

Monique Vallée

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Symptoms of mental disorders and oral contraception use: A systematic review and meta-analysis 精神障碍症状与口服避孕药的使用:一项系统回顾和荟萃分析。

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2023-11-14 DOI: 10.1016/j.yfrne.2023.101111

Mathilda Z. Kraft , Philine Rojczyk , Thomas Weiss , Birgit Derntl , Zora Kikinis , Ilona Croy , Carina Heller

{"title":"Symptoms of mental disorders and oral contraception use: A systematic review and meta-analysis","authors":"Mathilda Z. Kraft , Philine Rojczyk , Thomas Weiss , Birgit Derntl , Zora Kikinis , Ilona Croy , Carina Heller","doi":"10.1016/j.yfrne.2023.101111","DOIUrl":"10.1016/j.yfrne.2023.101111","url":null,"abstract":"<div><p>Worldwide, over 150 million adolescent and adult women use oral contraceptives (OC). An association between OC-use and the emergence of symptoms of mental disorders has been suggested. This systematic review and meta-analysis provide an overview of published research regarding symptoms of mental disorders in association with OC-use, factoring the influence of OC types, age of first-use, duration of OC-intake, and previous diagnoses of mental disorders. A systematic literature search was conducted between June-July 2022. 22 studies were included. While most found no significant OC-use effects on mental symptoms, some hinted at OCs as a potential risk. The existing evidence regarding the potential link between progestin-only OC-use and an elevated risk of mental symptoms in comparison to combined OC-use remains inconclusive. However, due to emerging indications suggesting that the formulation of OC might play a role in mental health outcomes, this topic warrants further investigation. Moreover, indications of an increased risk for depressive symptoms in adolescent OC-users should be noted. Hence, while general population effects seem unlikely, they cannot be completely disregarded. The decision on OC-use should depend on the patient's medical history and should be re-evaluated regularly.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"72 ","pages":"Article 101111"},"PeriodicalIF":7.4,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302223000596/pdfft?md5=5af9066c6f4133c8da5b56b6ae49e1ab&pid=1-s2.0-S0091302223000596-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Testosterone’s role in modulating human behaviors relevant to mating and parenting 睾丸素在调节人类交配和养育行为中的作用

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2023-11-14 DOI: 10.1016/j.yfrne.2023.101112

Francesca R. Luberti, Justin M. Carré

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Sex and gender in health research: Intersectionality matters 健康研究中的性与性别：交叉性问题

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2023-10-30 DOI: 10.1016/j.yfrne.2023.101104

Sivaniya Subramaniapillai , Liisa A.M. Galea , Gillian Einstein , Ann-Marie G. de Lange

{"title":"Sex and gender in health research: Intersectionality matters","authors":"Sivaniya Subramaniapillai , Liisa A.M. Galea , Gillian Einstein , Ann-Marie G. de Lange","doi":"10.1016/j.yfrne.2023.101104","DOIUrl":"10.1016/j.yfrne.2023.101104","url":null,"abstract":"<div><p>Research policies aiming to integrate sex and gender in scientific studies are receiving increased attention in academia. Incorporating these policies into health research is essential for improving targeted and equitable healthcare outcomes, by considering both disparities and similarities between individuals relating to sex and gender. Although these efforts are both urgent and critical, only an intersectional approach, which considers broad and multidimensional aspects of an individual's identity, can provide a complete understanding of the factors that impact health. In this commentary, we emphasize that in order to approach health equity, it is crucial to examine how sex and gender intersect with factors such as culture, ethnicity, minority status, and socioeconomic conditions to influence health outcomes. To facilitate evidence-based health interventions with tangible impact, we must consider disparities linked to both biological and environmental factors.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"72 ","pages":"Article 101104"},"PeriodicalIF":7.4,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302223000523/pdfft?md5=9cc0193adf637b1f9c1c3880b4553fca&pid=1-s2.0-S0091302223000523-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136152147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Neuroestradiol and neuronal development: Not an exclusive male tale anymore 神经雌二醇和神经元发育:不再是男性独有的故事

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2023-10-01 DOI: 10.1016/j.yfrne.2023.101102

Luis M. Garcia-Segura , Pablo Méndez , M. Angeles Arevalo , Iñigo Azcoitia

引用次数: 0