Frontiers in Neuroendocrinology最新文献_第10页

Pituitary multi-hormone cells in mammals and fish: history, origin, and roles 哺乳动物和鱼类的垂体多激素细胞:历史、起源和作用

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101018

Romain Fontaine, Muhammad Rahmad Royan, Christiaan Henkel, Kjetil Hodne, Eirill Ager-Wick, Finn-Arne Weltzien

{"title":"Pituitary multi-hormone cells in mammals and fish: history, origin, and roles","authors":"Romain Fontaine, Muhammad Rahmad Royan, Christiaan Henkel, Kjetil Hodne, Eirill Ager-Wick, Finn-Arne Weltzien","doi":"10.1016/j.yfrne.2022.101018","DOIUrl":"10.1016/j.yfrne.2022.101018","url":null,"abstract":"<div><p>The vertebrate pituitary is a dynamic organ, capable of adapting its hormone secretion to different physiological demands. In this context, endocrinologists have debated for the past 40 years if endocrine cells are mono- or multi-hormonal. Since its establishment, the dominant “one cell, one hormone” model has been continuously challenged. In mammals, the use of advanced multi-staining approaches, sensitive gene expression techniques, and the analysis of tumor tissues have helped to quickly demonstrate the existence of pituitary multi-hormone cells. In fishes however, only recent advances in imaging and transcriptomics have enabled the identification of such cells. In this review, we first describe the history of the discovery of cells producing multiple hormones in mammals and fishes. We discuss the technical limitations that have led to uncertainties and debates. Then, we present the current knowledge and hypotheses regarding their origin and biological role, which provides a comprehensive review of pituitary plasticity.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"67 ","pages":"Article 101018"},"PeriodicalIF":7.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302222000413/pdfft?md5=16eac614df2e9ff2b812f311db8f7f23&pid=1-s2.0-S0091302222000413-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40547741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A tribute to Gian Carlo Panzica (17 August 1949–21 July 2022) 向吉安·卡洛·潘齐卡致敬(1949年8月17日- 2022年7月21日)

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101034

Jacques Balthazart

引用次数: 0

Modeling hormonal contraception in female rats: A framework for studies in behavioral neurobiology 在雌性大鼠中模拟激素避孕:行为神经生物学研究的框架

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101020

Jesse M. Lacasse, Eamonn Gomez-Perales, Wayne G. Brake

引用次数: 7

Kisspeptin neuron electrophysiology: Intrinsic properties, hormonal modulation, and regulation of homeostatic circuits Kisspeptin神经元电生理学:内在特性、激素调节和自我平衡回路的调节

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-07-01 DOI: 10.1016/j.yfrne.2022.101006

Bradley B. Jamieson , Richard Piet

引用次数: 5

Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity 运动和长期突触增强:运动诱导的神经可塑性机制

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-07-01 DOI: 10.1016/j.yfrne.2022.100993

Wouter A.J. Vints , Oron Levin , Hakuei Fujiyama , Jeanine Verbunt , Nerijus Masiulis

{"title":"Exerkines and long-term synaptic potentiation: Mechanisms of exercise-induced neuroplasticity","authors":"Wouter A.J. Vints , Oron Levin , Hakuei Fujiyama , Jeanine Verbunt , Nerijus Masiulis","doi":"10.1016/j.yfrne.2022.100993","DOIUrl":"10.1016/j.yfrne.2022.100993","url":null,"abstract":"<div><p>Physical exercise may improve cognitive function by modulating molecular and cellular mechanisms within the brain. We propose that the facilitation of long-term synaptic potentiation (LTP)-related pathways, by products induced by physical exercise (i.e., exerkines), is a crucial aspect of the exercise-effect on the brain. This review summarizes synaptic pathways that are activated by exerkines and may potentiate LTP. For a total of 16 exerkines, we indicated how blood and brain exerkine levels are altered depending on the type of physical exercise (i.e., cardiovascular or resistance exercise) and how they respond to a single bout (i.e., acute exercise) or multiple bouts of physical exercise (i.e., chronic exercise). This information may be used for designing individualized physical exercise programs. Finally, this review may serve to direct future research towards fundamental gaps in our current knowledge regarding the biophysical interactions between muscle activity and the brain at both cellular and system levels.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"66 ","pages":"Article 100993"},"PeriodicalIF":7.4,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302222000164/pdfft?md5=8684c6a3f939fcdf822cd9e3faa94773&pid=1-s2.0-S0091302222000164-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72714497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

Methods and considerations for the use of hormonal contraceptives in rat models of neurobehavior 大鼠神经行为模型中使用激素避孕药的方法和考虑

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-07-01 DOI: 10.1016/j.yfrne.2022.101011

Emily N. Hilz

引用次数: 6

Can animal models resemble a premenstrual dysphoric condition? 动物模型能模拟经前烦躁吗?

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-07-01 DOI: 10.1016/j.yfrne.2022.101007

Estrada-Camarena Erika , Carolina López-Rubalcava

引用次数: 5

Metabolic hormones mediate cognition 代谢激素介导认知

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-07-01 DOI: 10.1016/j.yfrne.2022.101009

Olivia R. Ghosh-Swaby , Amy C. Reichelt , Paul A.S. Sheppard , Jeffrey Davies , Timothy J. Bussey , Lisa M. Saksida

引用次数: 4

The underlying sex differences in neuroendocrine adaptations relevant to Myalgic Encephalomyelitis Chronic Fatigue Syndrome 与肌痛性脑脊髓炎慢性疲劳综合征相关的神经内分泌适应的潜在性别差异

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-07-01 DOI: 10.1016/j.yfrne.2022.100995

Natalie Thomas , Caroline Gurvich , Katherine Huang , Paul R. Gooley , Christopher W. Armstrong

{"title":"The underlying sex differences in neuroendocrine adaptations relevant to Myalgic Encephalomyelitis Chronic Fatigue Syndrome","authors":"Natalie Thomas , Caroline Gurvich , Katherine Huang , Paul R. Gooley , Christopher W. Armstrong","doi":"10.1016/j.yfrne.2022.100995","DOIUrl":"10.1016/j.yfrne.2022.100995","url":null,"abstract":"<div><h3>Introduction</h3><p>Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS) is a complex multisystem disease characterised by severe and disabling new-onset symptoms of post-exertional malaise (PEM), fatigue, brain fog, and sleep dysfunction that lasts for at least six months. Accumulating evidence suggests that sex and endocrine events have a significant influence on symptom onset and moderation of ME/CFS, with female sex being one of the most consistent and credible predictive risk factors associated with diagnosis. Such sex differences suggest sex chromosomes and sex steroids may play a part in the development of the condition or moderation of symptoms, although this has yet to be explored in detail.</p></div><div><h3>Methods/Aims</h3><p>This narrative review outlines sex differences in ME/CFS in terms of vulnerability factors and clinical phenotype and explores the known sex differences in neuroendocrine systems affected in ME/CFS and how this may relate to disease risk, onset, pathophysiology, and potential treatment avenues.</p></div><div><h3>Conclusions</h3><p>There is clear evidence of a sex dimorphism with regards to prevalence (3:1 female preponderance), clinical phenotypes, and aetiological triggers prior to symptom onset of ME/CFS. Endocrinological events, particularly those throughout the female lifespan, are associated with ME/CFS and include reproductive menstrual cycle fluctuations, pregnancy, post-partum and perimenopause. Further, there is evidence for gonadal sex, adrenal stress and renal neuroendocrine systems as implicated in ME/CFS, including changes in estrogen, progesterone compounds, aldosterone, and cortisol levels, of which there are established sex differences. The broad effects of steroid hormones on the physiological systems may also speak to the diversity of ME/CFS symptomatology observed in patients. Further attention must be paid to sex, age, and steroid biology in ME/CFS.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"66 ","pages":"Article 100995"},"PeriodicalIF":7.4,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77891173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Timing is everything: Circadian rhythms and their role in the control of sleep 时间决定一切:昼夜节律及其在控制睡眠中的作用

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-07-01 DOI: 10.1016/j.yfrne.2022.100978

Seithikurippu R. Pandi-Perumal , Daniel P. Cardinali , Nevin F.W. Zaki , Ramanujam Karthikeyan , David Warren Spence , Russel J. Reiter , Gregory M. Brown

引用次数: 7