Frontiers in Neuroendocrinology最新文献_第9页

What is there to know about the effects of progestins on the human brain and cognition? 关于黄体酮对人类大脑和认知的影响，我们知道些什么?

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101032

Ramune Griksiene, Rasa Monciunskaite, Osvaldas Ruksenas

引用次数: 6

Review of the effects of polycystic ovary syndrome on Cognition: Looking beyond the androgen hypothesis 多囊卵巢综合征对认知的影响综述:超越雄激素假说

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101038

Mateja Perović , Katrina Wugalter , Gillian Einstein

引用次数: 3

Structural and functional brain alterations in Cushing’s disease: A narrative review 库欣病的脑结构和功能改变:叙述性回顾

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101033

Yi-Fan Liu , Lei Pan , Ming Feng

{"title":"Structural and functional brain alterations in Cushing’s disease: A narrative review","authors":"Yi-Fan Liu , Lei Pan , Ming Feng","doi":"10.1016/j.yfrne.2022.101033","DOIUrl":"10.1016/j.yfrne.2022.101033","url":null,"abstract":"<div><p>Neurocognitive and psychiatric symptoms are non-negligible in Cushing’s disease and are accompanied by structural and functional alterations of the brain. In this review, we have summarized multimodal neuroimaging and neurophysiological studies to highlight the current and historical understandings of the structural and functional brain alterations in Cushing’s disease. Specifically, structural studies showed atrophy of the gray matter, loss of white matter integrity, and demyelination in widespread brain regions. Functional imaging studies have identified three major functional brain connectome networks influenced by hypercortisolemia: the limbic network, the default mode network<span>, and the executive control network. After endocrinological remission, atrophy of gray matter regions and the compromised functional network activities were partially reversible, and the widespread white matter integrity alterations cannot recover in years. In conclusion, Cushing’s disease patients display structural and functional brain connectomic alterations, which provides insights into the neurocognitive and psychiatric symptoms observed in this disease.</span></p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"67 ","pages":"Article 101033"},"PeriodicalIF":7.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40372984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Hormone-based models for comparing menstrual cycle and hormonal contraceptive effects on human resting-state functional connectivity 比较月经周期和激素避孕对人类静息状态功能连接影响的激素模型

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101036

Kathleen V. Casto , Timothy Jordan , Nicole Petersen

{"title":"Hormone-based models for comparing menstrual cycle and hormonal contraceptive effects on human resting-state functional connectivity","authors":"Kathleen V. Casto , Timothy Jordan , Nicole Petersen","doi":"10.1016/j.yfrne.2022.101036","DOIUrl":"10.1016/j.yfrne.2022.101036","url":null,"abstract":"<div><p>Oral contraceptives (OCs) are widely used yet understudied given their potential for public health consequences. Emerging investigations scaling from single-subject, dense-sampling neuroimaging studies to population-level metrics have linked OCs to altered brain structure and function. Modeling the hypogonadal, hypergonadal, or mixed state effects of OCs in terms of their impact on hormone action in the brain is a valuable approach to synthesizing results across neuroimaging studies and comparing OC effects to companion findings from research on menstrual cycle phase effects on brain anatomy and function. Resting-state functional connectivity studies provide a powerful tool to evaluate the role of OCs on the intrinsic network connectivity that underlies multiple behavioral domains. The preponderance (but not consensus) of the current literature indicates that (1) as the menstrual cycle proceeds from a low to high progesterone state, prefrontal connectivity increases and parietal connectivity decreases; (2) OCs tend to mimic this connectivity pattern; therefore (3) OCs may produce a hyperprogestogenic state in the brain, in spite of overall reductions in endogenous steroid hormone levels. Alternative models are also considered.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"67 ","pages":"Article 101036"},"PeriodicalIF":7.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/02/nihms-1840928.PMC9649880.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40372985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Hormonal contraceptives, stress, and the brain: The critical need for animal models 激素避孕药，压力和大脑:动物模型的迫切需要

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101035

Natalie C. Tronson, Kristen M. Schuh

引用次数: 7

The impact of hormonal contraceptives on anxiety treatments: From preclinical models to clinical settings 激素避孕药对焦虑治疗的影响:从临床前模型到临床设置

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101030

Bronwyn M. Graham

引用次数: 4

Imaging the human brain on oral contraceptives: A review of structural imaging methods and implications for future research goals 口服避孕药成像人脑:结构成像方法的回顾和对未来研究目标的影响

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101031

Carina Heller , Ann-Christin S. Kimmig , Marek R. Kubicki , Birgit Derntl , Zora Kikinis

引用次数: 4

Pituitary multi-hormone cells in mammals and fish: history, origin, and roles 哺乳动物和鱼类的垂体多激素细胞:历史、起源和作用

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101018

Romain Fontaine, Muhammad Rahmad Royan, Christiaan Henkel, Kjetil Hodne, Eirill Ager-Wick, Finn-Arne Weltzien

{"title":"Pituitary multi-hormone cells in mammals and fish: history, origin, and roles","authors":"Romain Fontaine, Muhammad Rahmad Royan, Christiaan Henkel, Kjetil Hodne, Eirill Ager-Wick, Finn-Arne Weltzien","doi":"10.1016/j.yfrne.2022.101018","DOIUrl":"10.1016/j.yfrne.2022.101018","url":null,"abstract":"<div><p>The vertebrate pituitary is a dynamic organ, capable of adapting its hormone secretion to different physiological demands. In this context, endocrinologists have debated for the past 40 years if endocrine cells are mono- or multi-hormonal. Since its establishment, the dominant “one cell, one hormone” model has been continuously challenged. In mammals, the use of advanced multi-staining approaches, sensitive gene expression techniques, and the analysis of tumor tissues have helped to quickly demonstrate the existence of pituitary multi-hormone cells. In fishes however, only recent advances in imaging and transcriptomics have enabled the identification of such cells. In this review, we first describe the history of the discovery of cells producing multiple hormones in mammals and fishes. We discuss the technical limitations that have led to uncertainties and debates. Then, we present the current knowledge and hypotheses regarding their origin and biological role, which provides a comprehensive review of pituitary plasticity.</p></div>","PeriodicalId":12469,"journal":{"name":"Frontiers in Neuroendocrinology","volume":"67 ","pages":"Article 101018"},"PeriodicalIF":7.4,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0091302222000413/pdfft?md5=16eac614df2e9ff2b812f311db8f7f23&pid=1-s2.0-S0091302222000413-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40547741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A tribute to Gian Carlo Panzica (17 August 1949–21 July 2022) 向吉安·卡洛·潘齐卡致敬(1949年8月17日- 2022年7月21日)

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101034

Jacques Balthazart

引用次数: 0

Modeling hormonal contraception in female rats: A framework for studies in behavioral neurobiology 在雌性大鼠中模拟激素避孕:行为神经生物学研究的框架

IF 7.4 1区医学

Frontiers in Neuroendocrinology Pub Date : 2022-10-01 DOI: 10.1016/j.yfrne.2022.101020

Jesse M. Lacasse, Eamonn Gomez-Perales, Wayne G. Brake

引用次数: 7