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Getting a Handle on Redox Regulation of RAS-Targeted Cysteine-Directed Inhibitors 处理ras靶向半胱氨酸抑制剂的氧化还原调控
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.064
Surbhi Mundra, Derek Parsonage, Maria L. Carneiro Buchele, Tom E. Forshaw, Venkat R. Chirasani, Hanzhi Wu, Jingyun Lee, Cristina M. Furdui, Leslie B. Poole, Sharon L. Campbell
{"title":"Getting a Handle on Redox Regulation of RAS-Targeted Cysteine-Directed Inhibitors","authors":"Surbhi Mundra, Derek Parsonage, Maria L. Carneiro Buchele, Tom E. Forshaw, Venkat R. Chirasani, Hanzhi Wu, Jingyun Lee, Cristina M. Furdui, Leslie B. Poole, Sharon L. Campbell","doi":"10.1016/j.freeradbiomed.2026.08.064","DOIUrl":"10.1016/j.freeradbiomed.2026.08.064","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S3"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathway Analysis of Mice Lacking Methionine Sulfoxide Reductases Highlights Mitochondrial Proteostasis Failure and Immune Suppression 缺乏甲硫氨酸亚砜还原酶的小鼠线粒体蛋白平衡失败和免疫抑制的途径分析
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.093
Vanessa Trindade Bortoluzzi, Shane Bryan, Kevin Welle, Sina Ghaemmaghami, Rodney Levine
{"title":"Pathway Analysis of Mice Lacking Methionine Sulfoxide Reductases Highlights Mitochondrial Proteostasis Failure and Immune Suppression","authors":"Vanessa Trindade Bortoluzzi, Shane Bryan, Kevin Welle, Sina Ghaemmaghami, Rodney Levine","doi":"10.1016/j.freeradbiomed.2026.08.093","DOIUrl":"10.1016/j.freeradbiomed.2026.08.093","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S12"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitochondrial Bioenergetics and Substrate Utilization of Megakaryocytes in Metabolic Overload 代谢负荷下巨核细胞的线粒体生物能量学和底物利用
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.101
Thomas Rollin, Kimberly J. Dunham-Snary
{"title":"Mitochondrial Bioenergetics and Substrate Utilization of Megakaryocytes in Metabolic Overload","authors":"Thomas Rollin, Kimberly J. Dunham-Snary","doi":"10.1016/j.freeradbiomed.2026.08.101","DOIUrl":"10.1016/j.freeradbiomed.2026.08.101","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S14"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catalyzed Reductive Nitrosylation of Myoglobin 肌红蛋白的催化还原亚硝基化
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.121
Thilini Karunarathna, Stephen R. Baker, Troy A. Stich, Matthew R. Dent, Jesús Tejero, Elizabeth R. Rochon, Anthony W. DeMartino, Mark T. Gladwin, Daniel B. Kim-Shapiro
{"title":"Catalyzed Reductive Nitrosylation of Myoglobin","authors":"Thilini Karunarathna, Stephen R. Baker, Troy A. Stich, Matthew R. Dent, Jesús Tejero, Elizabeth R. Rochon, Anthony W. DeMartino, Mark T. Gladwin, Daniel B. Kim-Shapiro","doi":"10.1016/j.freeradbiomed.2026.08.121","DOIUrl":"10.1016/j.freeradbiomed.2026.08.121","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S19-S20"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochelatin 2, a Diet-derived dithiol, Protects Against Cadmium Accumulation and Contributes to a Reducing Environment in the Testes 植物螯合素2是一种膳食来源的二硫醇，可防止睾丸中镉的积累并有助于减少环境
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.087
Zachery Jarrell, Ho Young Lee, Choon-Myung Lee, Michael Orr, Dean Jones, Young-Mi Go
{"title":"Phytochelatin 2, a Diet-derived dithiol, Protects Against Cadmium Accumulation and Contributes to a Reducing Environment in the Testes","authors":"Zachery Jarrell, Ho Young Lee, Choon-Myung Lee, Michael Orr, Dean Jones, Young-Mi Go","doi":"10.1016/j.freeradbiomed.2026.08.087","DOIUrl":"10.1016/j.freeradbiomed.2026.08.087","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S10"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endothelial Cells and Skeletal Muscle Fibers Exhibit Distinct Transcriptional Redox-Regulatory Responses During Early Exercise Recovery 内皮细胞和骨骼肌纤维在早期运动恢复中表现出不同的转录氧化还原调节反应
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.129
Rebecca M. Wall, Adele K. Addington, Xuemei Zhang, Siobhan M. Craige
{"title":"Endothelial Cells and Skeletal Muscle Fibers Exhibit Distinct Transcriptional Redox-Regulatory Responses During Early Exercise Recovery","authors":"Rebecca M. Wall, Adele K. Addington, Xuemei Zhang, Siobhan M. Craige","doi":"10.1016/j.freeradbiomed.2026.08.129","DOIUrl":"10.1016/j.freeradbiomed.2026.08.129","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S22"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iron- and 2-Oxoglutarate-Dependent Oxygenases: The Role of Oxygen In Tissue Remodeling By Lung Fibroblasts 铁和2-氧戊二酸依赖的加氧酶：氧在肺成纤维细胞组织重塑中的作用
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.130
William Willmore
{"title":"Iron- and 2-Oxoglutarate-Dependent Oxygenases: The Role of Oxygen In Tissue Remodeling By Lung Fibroblasts","authors":"William Willmore","doi":"10.1016/j.freeradbiomed.2026.08.130","DOIUrl":"10.1016/j.freeradbiomed.2026.08.130","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S22"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nitrated Nerve Growth Factor (NO2NGF) as a Pathogenic Hallmark in Neurodegenerative Diseases 硝化神经生长因子（NO2NGF）作为神经退行性疾病的致病标志
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.104
Santiago Garcimartin, Nicolás Campolo, Mauricio Mastrogiovanni, Ari Zeida, Valentina Varela, Emiliano Trias, Luis Barbeito, Rosario Duran, Ángeles Almeida, Rafael Radi, María Delgado-Esteban, Silvina Bartesaghi
{"title":"Nitrated Nerve Growth Factor (NO2NGF) as a Pathogenic Hallmark in Neurodegenerative Diseases","authors":"Santiago Garcimartin, Nicolás Campolo, Mauricio Mastrogiovanni, Ari Zeida, Valentina Varela, Emiliano Trias, Luis Barbeito, Rosario Duran, Ángeles Almeida, Rafael Radi, María Delgado-Esteban, Silvina Bartesaghi","doi":"10.1016/j.freeradbiomed.2026.08.104","DOIUrl":"10.1016/j.freeradbiomed.2026.08.104","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S15"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acteoside Suppresses MPO/HOCl/ds-HMGB1/NLRP3 Axis and Attenuates Hemorrhagic Transformation in Experimental Ischemic Stroke Rats with Delayed Thrombolysis 毛蕊花苷抑制实验性缺血性脑卒中迟发性溶栓大鼠MPO/HOCl/ds-HMGB1/NLRP3轴及出血转化
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.107
Jiangang Shen, Shuang Chen, Ao Shang, Shangwen Jing
{"title":"Acteoside Suppresses MPO/HOCl/ds-HMGB1/NLRP3 Axis and Attenuates Hemorrhagic Transformation in Experimental Ischemic Stroke Rats with Delayed Thrombolysis","authors":"Jiangang Shen, Shuang Chen, Ao Shang, Shangwen Jing","doi":"10.1016/j.freeradbiomed.2026.08.107","DOIUrl":"10.1016/j.freeradbiomed.2026.08.107","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S16"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytocannabinoids and the impact on redox and immune responses: In Vitro and In Silico Studies. 植物大麻素及其对氧化还原和免疫反应的影响：体外和计算机研究。
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.115
Cameron Danville, Pratham Ghimire, Jayden Arroyo, Ileini Espino, Alyssa Eddy, Carlos Kofroth, Yuna Batson, Kelly Theisen, Karina Ckless
{"title":"Phytocannabinoids and the impact on redox and immune responses: In Vitro and In Silico Studies.","authors":"Cameron Danville, Pratham Ghimire, Jayden Arroyo, Ileini Espino, Alyssa Eddy, Carlos Kofroth, Yuna Batson, Kelly Theisen, Karina Ckless","doi":"10.1016/j.freeradbiomed.2026.08.115","DOIUrl":"10.1016/j.freeradbiomed.2026.08.115","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S18"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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