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Pro-Oxidant Effect of Quercetin is Related with Depression of TRX-Dependent System and mTOR/STAT3 Signaling Pathway in Cisplatin-Resistant Cancer Cells 槲皮素的促氧化作用与抑制顺铂耐药癌细胞trx依赖系统和mTOR/STAT3信号通路有关
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.069
Aseel Hasan, Elena Kalinina, Yulia Volodina, Julia Nuzhina, Alexander Shtil, Victor Tatarskiy
{"title":"Pro-Oxidant Effect of Quercetin is Related with Depression of TRX-Dependent System and mTOR/STAT3 Signaling Pathway in Cisplatin-Resistant Cancer Cells","authors":"Aseel Hasan, Elena Kalinina, Yulia Volodina, Julia Nuzhina, Alexander Shtil, Victor Tatarskiy","doi":"10.1016/j.freeradbiomed.2026.08.069","DOIUrl":"10.1016/j.freeradbiomed.2026.08.069","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S4-S5"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rebalancing the Hemoglobin Redox Axis Through Kinetically Programmed Nanodelivery of Methylene Blue 通过亚甲基蓝的动力学编程纳米递送重新平衡血红蛋白氧化还原轴
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.117
Lamiya Hassan Tithy, Regina Adao, Mary Brummet, Bhaskar Kandregula, Mette Jacobsen, Elizabeth Zheleznyakova, Elizabeth Ruby McAslan, Esma Alp, Fantao Meng, Stephen C. Rogers, Allan Doctor
{"title":"Rebalancing the Hemoglobin Redox Axis Through Kinetically Programmed Nanodelivery of Methylene Blue","authors":"Lamiya Hassan Tithy, Regina Adao, Mary Brummet, Bhaskar Kandregula, Mette Jacobsen, Elizabeth Zheleznyakova, Elizabeth Ruby McAslan, Esma Alp, Fantao Meng, Stephen C. Rogers, Allan Doctor","doi":"10.1016/j.freeradbiomed.2026.08.117","DOIUrl":"10.1016/j.freeradbiomed.2026.08.117","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S18-S19"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Nitroalkene (E)-8-nitrononadec-7-enoic Acid (CP-8) is a Reversible Covalent Inhibitor of DNA -DSB Repair and Activator of Adaptive PD-L1 Signaling in Ovarian Cancer 硝基烯(E)-8-硝基膦酸-7-烯酸（CP-8）是卵巢癌DNA -DSB修复的可逆共价抑制剂和适应性PD-L1信号通路的激活剂
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.075
Priscilla Tang, Lisa Hong, Sarah Alsaad, Sierra White, Dennis Braden, John Skoko, Nadine Hempel, Lan Coffman, Francisco Schopfer, Carola Neumann
{"title":"The Nitroalkene (E)-8-nitrononadec-7-enoic Acid (CP-8) is a Reversible Covalent Inhibitor of DNA -DSB Repair and Activator of Adaptive PD-L1 Signaling in Ovarian Cancer","authors":"Priscilla Tang, Lisa Hong, Sarah Alsaad, Sierra White, Dennis Braden, John Skoko, Nadine Hempel, Lan Coffman, Francisco Schopfer, Carola Neumann","doi":"10.1016/j.freeradbiomed.2026.08.075","DOIUrl":"10.1016/j.freeradbiomed.2026.08.075","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S6"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redox regulation of Platelet Glycoprotein VI Signaling by SOD Mimetic in Inflammatory Conditions 炎症条件下SOD模拟物对血小板糖蛋白VI信号的氧化还原调节
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.091
William Osier, Daniel Colon Hidalgo, Janelle Posey, Peter Harris, Diana Nelson, Prerana Vishwanath, Rebecca Oberley-Deegan, James Roede, Caitlin Lewis, Kristofer Fritz, Christina Sul, Cassidy Delaney, Eva Nozik
{"title":"Redox regulation of Platelet Glycoprotein VI Signaling by SOD Mimetic in Inflammatory Conditions","authors":"William Osier, Daniel Colon Hidalgo, Janelle Posey, Peter Harris, Diana Nelson, Prerana Vishwanath, Rebecca Oberley-Deegan, James Roede, Caitlin Lewis, Kristofer Fritz, Christina Sul, Cassidy Delaney, Eva Nozik","doi":"10.1016/j.freeradbiomed.2026.08.091","DOIUrl":"10.1016/j.freeradbiomed.2026.08.091","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S11"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preventing DHA Oxidation Using Deuterated DHA Ameliorates Neonatal Hypoxic Ischemic Brain Injury 使用氘化DHA防止DHA氧化可改善新生儿缺氧缺血性脑损伤
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.108
Joseph Vithayathil, Anjali Shankar, Mikhail S. Shchepinov, Frances E. Jensen, Delia Talos MD, Joshua Dunaief
{"title":"Preventing DHA Oxidation Using Deuterated DHA Ameliorates Neonatal Hypoxic Ischemic Brain Injury","authors":"Joseph Vithayathil, Anjali Shankar, Mikhail S. Shchepinov, Frances E. Jensen, Delia Talos MD, Joshua Dunaief","doi":"10.1016/j.freeradbiomed.2026.08.108","DOIUrl":"10.1016/j.freeradbiomed.2026.08.108","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S16"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterizing Effects of the Liver Microenvironment in Uveal Melanoma 肝脏微环境对葡萄膜黑色素瘤的影响
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.068
Elizabeth A. Homer, Alyssa Monteleone-Haught, Amirali Amirfallah, Kayla Gallant, Camille Cunanan, Joshua Jackson, Edward Hartsough
{"title":"Characterizing Effects of the Liver Microenvironment in Uveal Melanoma","authors":"Elizabeth A. Homer, Alyssa Monteleone-Haught, Amirali Amirfallah, Kayla Gallant, Camille Cunanan, Joshua Jackson, Edward Hartsough","doi":"10.1016/j.freeradbiomed.2026.08.068","DOIUrl":"10.1016/j.freeradbiomed.2026.08.068","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S4"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hsp90 Nitration Promotes Glioblastoma Proliferation via P2X7R Signaling and Defines a Site-Selective Therapeutic Target Hsp90硝化通过P2X7R信号传导促进胶质母细胞瘤增殖并确定一个位点选择性治疗靶点
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.066
Inge Claassen, Nirbachita Adrita, Oszkar Szentirmai, Maria Clara Franco
{"title":"Hsp90 Nitration Promotes Glioblastoma Proliferation via P2X7R Signaling and Defines a Site-Selective Therapeutic Target","authors":"Inge Claassen, Nirbachita Adrita, Oszkar Szentirmai, Maria Clara Franco","doi":"10.1016/j.freeradbiomed.2026.08.066","DOIUrl":"10.1016/j.freeradbiomed.2026.08.066","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S3-S4"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antioxidant Peptides Based on a Necrostatin Scaffold 基于Necrostatin支架的抗氧化肽
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.118
Surya I. Amundsen, Mariposa Davis, Elyse Hassett, Benjamin Ginsberg, Brian Day, Robert J. Hondal
{"title":"Antioxidant Peptides Based on a Necrostatin Scaffold","authors":"Surya I. Amundsen, Mariposa Davis, Elyse Hassett, Benjamin Ginsberg, Brian Day, Robert J. Hondal","doi":"10.1016/j.freeradbiomed.2026.08.118","DOIUrl":"10.1016/j.freeradbiomed.2026.08.118","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S19"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perfluorooctanesulfonic Acid (PFOS) and Glucose Exposures Alter Pancreatic Islet Vascularization During Development in Zebrafish (Danio Rerio) 全氟辛烷磺酸（PFOS）和葡萄糖暴露改变斑马鱼发育过程中胰岛血管化（Danio Rerio）
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.088
Augustine Sobo, Madeline Tompach, Jason Hansen, Alicia Timme-Laragy
{"title":"Perfluorooctanesulfonic Acid (PFOS) and Glucose Exposures Alter Pancreatic Islet Vascularization During Development in Zebrafish (Danio Rerio)","authors":"Augustine Sobo, Madeline Tompach, Jason Hansen, Alicia Timme-Laragy","doi":"10.1016/j.freeradbiomed.2026.08.088","DOIUrl":"10.1016/j.freeradbiomed.2026.08.088","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S10"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ergothioneine Binds Iron: Definitive Evidence and Determination of the Binding Constants 麦角硫因结合铁：明确证据和结合常数的测定
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.110
Quinn Bennett, Clorice Reinhardt, Robert Hondal
{"title":"Ergothioneine Binds Iron: Definitive Evidence and Determination of the Binding Constants","authors":"Quinn Bennett, Clorice Reinhardt, Robert Hondal","doi":"10.1016/j.freeradbiomed.2026.08.110","DOIUrl":"10.1016/j.freeradbiomed.2026.08.110","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S17"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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