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Loss of NOX4 Disrupts Exercise-Induced Mitochondrial Quality Control in Skeletal Muscle NOX4的缺失破坏了骨骼肌运动诱导的线粒体质量控制
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.103
Rebecca M. Wall, Ryan N. Montalvo, Kalyn S. Jenkins, Adele K. Addington, Abhinav Krishnan, Joshua C. Drake, Zhen Yan, Siobhan M. Craige
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引用次数: 0
Targeting GLOD4 Reduces Pathological α-Synuclein and Protects Dopaminergic Neurons in Models of Parkinson’s Disease 靶向GLOD4在帕金森病模型中减少病理性α-突触核蛋白并保护多巴胺能神经元
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.106
Sahar Mazhar, Tiffany Thaphasouk, Robert van der Linden, Frank Kayser, Irene Griswold-Prenner
{"title":"Targeting GLOD4 Reduces Pathological α-Synuclein and Protects Dopaminergic Neurons in Models of Parkinson’s Disease","authors":"Sahar Mazhar, Tiffany Thaphasouk, Robert van der Linden, Frank Kayser, Irene Griswold-Prenner","doi":"10.1016/j.freeradbiomed.2026.08.106","DOIUrl":"10.1016/j.freeradbiomed.2026.08.106","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S15-S16"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal Remodeling of Mitochondrial Pathways Reveals Persistent Bioenergetic Dysfunction in Cisplatin-Induced Cognitive Impairment 顺铂诱导的认知障碍中线粒体通路的时间重构揭示了持续的生物能量功能障碍
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.072
Rajasekaran Mahalingam, Anand K. Singh, Shruthi Dharmarj, Heidi Miriam Zamorani, Cobi J. Heijnen
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引用次数: 0
EC-SOD Compartmentalization Differentially Regulates Innate Immune Responses in Hypoxic Pulmonary Hypertension EC-SOD区隔化对低氧性肺动脉高压先天免疫反应的差异调控
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.083
Caitlin Lewis, Janelle Posey, Thi-Tina Nguyen, Amelia Rosin, Tim Porfilio, Nathan Dee, Mariah Jordan, Samuel Burciaga, Daniel Colon Hidalgo, Christina Sul, Cassidy Delaney, Eva Nozik
{"title":"EC-SOD Compartmentalization Differentially Regulates Innate Immune Responses in Hypoxic Pulmonary Hypertension","authors":"Caitlin Lewis, Janelle Posey, Thi-Tina Nguyen, Amelia Rosin, Tim Porfilio, Nathan Dee, Mariah Jordan, Samuel Burciaga, Daniel Colon Hidalgo, Christina Sul, Cassidy Delaney, Eva Nozik","doi":"10.1016/j.freeradbiomed.2026.08.083","DOIUrl":"10.1016/j.freeradbiomed.2026.08.083","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S9"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redox Sensitivity of Pyridoxal 5'-Phosphate-Dependent Catalysis in Antibiotic Biosynthesis: Mechanistic Investigation of AprL from the Apramycin Pathway 吡哆醛5'-磷酸依赖性催化在抗生素生物合成中的氧化还原敏感性：阿帕霉素途径AprL的机制研究
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.085
Oluwaseun Ajayi, Robert Phillips
{"title":"Redox Sensitivity of Pyridoxal 5'-Phosphate-Dependent Catalysis in Antibiotic Biosynthesis: Mechanistic Investigation of AprL from the Apramycin Pathway","authors":"Oluwaseun Ajayi, Robert Phillips","doi":"10.1016/j.freeradbiomed.2026.08.085","DOIUrl":"10.1016/j.freeradbiomed.2026.08.085","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S9-S10"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Measuring mitochondrial function in primary and immortalized epithelial airway air liquid interface cultures 测定原代和永生化上皮气道气液界面培养的线粒体功能
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.097
Kathryn M. Crotty, Joseph Shapiro, Guiying Cui, John Moran, Catherine Foye, Kathryn E. Oliver, Benjamin Kopp, Nael McCarty, Joshua D. Chandler
{"title":"Measuring mitochondrial function in primary and immortalized epithelial airway air liquid interface cultures","authors":"Kathryn M. Crotty, Joseph Shapiro, Guiying Cui, John Moran, Catherine Foye, Kathryn E. Oliver, Benjamin Kopp, Nael McCarty, Joshua D. Chandler","doi":"10.1016/j.freeradbiomed.2026.08.097","DOIUrl":"10.1016/j.freeradbiomed.2026.08.097","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S13"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ganglioside GD3 Promotes Skeletal Muscle Regeneration Through its Antioxidant Activity 神经节苷脂GD3通过其抗氧化活性促进骨骼肌再生
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.128
Yuka Taniwaki, Masaki Nagane, Yuko Fujiwara, Kotaro Hama, Kazuaki Yokoyama, Hibiki Tatsumi, Hinano Mizugaki, Naoyuki Aihara, Takanori Shiga, Junichi Kamiie, Yuko Naya, Tadashi Yamashita
{"title":"Ganglioside GD3 Promotes Skeletal Muscle Regeneration Through its Antioxidant Activity","authors":"Yuka Taniwaki, Masaki Nagane, Yuko Fujiwara, Kotaro Hama, Kazuaki Yokoyama, Hibiki Tatsumi, Hinano Mizugaki, Naoyuki Aihara, Takanori Shiga, Junichi Kamiie, Yuko Naya, Tadashi Yamashita","doi":"10.1016/j.freeradbiomed.2026.08.128","DOIUrl":"10.1016/j.freeradbiomed.2026.08.128","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Pages S21-S22"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Nuclear Redox-Switch Drives Chromatin Remodeling in Cancer 核氧化还原开关驱动癌症中的染色质重塑
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.074
Flavio Romero Palma, Silver Homa, Hannah Kim, Melike Lakadamyali, Marcelo G. Bonini
{"title":"A Nuclear Redox-Switch Drives Chromatin Remodeling in Cancer","authors":"Flavio Romero Palma, Silver Homa, Hannah Kim, Melike Lakadamyali, Marcelo G. Bonini","doi":"10.1016/j.freeradbiomed.2026.08.074","DOIUrl":"10.1016/j.freeradbiomed.2026.08.074","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S6"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Functional Mass Spectrometry Imaging to Detect Spatial Heterogeneity in Glutathione Metabolic Rates in Mouse Tissues 开发功能质谱成像检测小鼠组织中谷胱甘肽代谢率的空间异质性
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.096
Sean J. Cone, Emily R. Bruce, David C. Muddiman, Michael P. Gamcsik
{"title":"Development of Functional Mass Spectrometry Imaging to Detect Spatial Heterogeneity in Glutathione Metabolic Rates in Mouse Tissues","authors":"Sean J. Cone, Emily R. Bruce, David C. Muddiman, Michael P. Gamcsik","doi":"10.1016/j.freeradbiomed.2026.08.096","DOIUrl":"10.1016/j.freeradbiomed.2026.08.096","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S13"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nitric Oxide-Mediated Redox Cycles Regulating Neurovascular Coupling to Improve Cognition in Neurodegeneration 一氧化氮介导的氧化还原循环调节神经血管耦合以改善神经变性患者的认知
IF 8 2区 生物学
Free Radical Biology and Medicine Pub Date : 2026-09-01 Epub Date: 2026-09-23 DOI: 10.1016/j.freeradbiomed.2026.08.105
João Laranjinha, Cátia Lourenço
{"title":"Nitric Oxide-Mediated Redox Cycles Regulating Neurovascular Coupling to Improve Cognition in Neurodegeneration","authors":"João Laranjinha, Cátia Lourenço","doi":"10.1016/j.freeradbiomed.2026.08.105","DOIUrl":"10.1016/j.freeradbiomed.2026.08.105","url":null,"abstract":"","PeriodicalId":12407,"journal":{"name":"Free Radical Biology and Medicine","volume":"253 ","pages":"Page S15"},"PeriodicalIF":8.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149028230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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