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Tuberculous Meningitis Presenting with Bilateral Optic Neuritis: A Case Report and Review of Literature 结核性脑膜炎伴双侧视神经炎:病例报告和文献综述
IF 0.7
Case Reports in Neurology Pub Date : 2024-01-09 DOI: 10.1159/000536086
Khaled W. Sadek, Mohamed A. Atta, Najwa Y. Sultan, Anas A. Ashour
{"title":"Tuberculous Meningitis Presenting with Bilateral Optic Neuritis: A Case Report and Review of Literature","authors":"Khaled W. Sadek, Mohamed A. Atta, Najwa Y. Sultan, Anas A. Ashour","doi":"10.1159/000536086","DOIUrl":"https://doi.org/10.1159/000536086","url":null,"abstract":"Introduction: Tuberculosis (TB) is a major global cause of morbidity and mortality. Tuberculous meningitis (TBM) is an implication of systemic dissemination of a primary TB infection that indicates a poorer disease prognosis with various long term neurological sequalae. Consequently, it is crucial to understand different clinical presentations and manifestations of such condition. In TBM, vision loss, which is one of the most devastating complications, may result from optic nerve inflammation and atrophy. Although unilateral optic neuritis as a primary presenting symptom of TBM has been broadly reported in the literature, there is paucity of information related to several other rare neuro-ophthalmic features, such as bilateral optic nerve involvement in TBM.\u0000Case presentation: We herein present a case of a 37 years-old Indian male patient presenting with unilateral vision loss that subsequently progressed to bilateral vision loss and was hence diagnosed with bilateral optic neuritis. Additional thorough investigation yielded a diagnosis of TBM with underlying tuberculomas. The patient’s condition improved afterwards with anti-tuberculous therapy and steroids with a follow up magnetic resonance imaging indicating radiological resolution as well. \u0000Conclusion: The differential diagnosis of bilateral optic neuritis is broad but a rare, yet an overlooked one would be central nervous system TB in form of meningitis or tuberculoma. Hence, it is important to identify bilateral optic neuritis as a possible rare presenting symptom of an underlying central nervous system TB infection which could lead to a faster disease diagnosis and treatment to prevent its devastating complications. \u0000","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"7 9","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139443750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Posterior circulation mechanical thrombectomy through primitive trigeminal artery: A case report 通过原始三叉动脉进行后循环机械血栓切除术:病例报告
IF 0.7
Case Reports in Neurology Pub Date : 2024-01-02 DOI: 10.1159/000535871
Xiaoshan Gao, Tianhong Wang, Jun Chen, Jiangjun Chen, Ying Wang, Kui Yang, Youquan Gu, Lihe Yao
{"title":"Posterior circulation mechanical thrombectomy through primitive trigeminal artery: A case report","authors":"Xiaoshan Gao, Tianhong Wang, Jun Chen, Jiangjun Chen, Ying Wang, Kui Yang, Youquan Gu, Lihe Yao","doi":"10.1159/000535871","DOIUrl":"https://doi.org/10.1159/000535871","url":null,"abstract":"Introduction: Primitive trigeminal artery (PTA) is a rare intracranial vascular malformation, and mechanical thrombectomy and revascularization via PTA are rarely reported. \u0000Case presentation: We reported a case of mechanical thrombectomy through PTA in a patient who presented with sudden slurred speech and had a National Institutes of Health Stroke Scale score of 12. Digital subtraction angiography of the cerebral vasculature showed PTA formation in the right internal carotid artery cavernous segment, with acute occlusion of the distal basilar artery at the PTA junction, and bilateral vertebral arteries and proximal basilar artery were underdeveloped. Therefore, we chose mechanical thrombectomy via PTA; but unfortunately, the vessel failed to recanalize. Follow-up at 1 month post-procedure indicated that the patient had passed away. We present the endovascular process and analyze and summarize the reasons for the failure to provide a reference for subsequent mechanical thrombectomy via PTA. \u0000Conclusions: PTA increases the risk of ischemic stroke and adds to the complexity of mechanical thrombectomy post-stroke. However, in certain situations, PTA can be used as a thrombectomy channel to increase the first-line possibility of timely endovascular treatment to save ischemic brain tissue.\u0000","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"11 5","pages":""},"PeriodicalIF":0.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139452511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early Manifestation of Benign Paroxysmal Positional Vertigo: A Case Report 良性阵发性位置性眩晕的早期表现:病例报告
IF 0.7
Case Reports in Neurology Pub Date : 2023-12-07 DOI: 10.1159/000535550
Matyas Ebel, Alena Jahodova, Jaroslav Jeřábek
{"title":"Early Manifestation of Benign Paroxysmal Positional Vertigo: A Case Report","authors":"Matyas Ebel, Alena Jahodova, Jaroslav Jeřábek","doi":"10.1159/000535550","DOIUrl":"https://doi.org/10.1159/000535550","url":null,"abstract":"we report a case of a 4.5-month-old infant with paroxysmal horizontal nystagmus, provoked by positioning. The clinical findings and successful resolution with repositioning manoeuvres indicate a diagnosis of right lateral semicircular canal lithiasis. This case report contributes to the existing literature by describing BPPV in the youngest age group, as no patients under 5 years have been previously reported. In order to document the case we also present a semi-automatic video analysis pipeline for analyzing abnormal eye movements in a home setting.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 5","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138590189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electroencephalographic abnormalities in a patient suffering from long-term neuropsychological complications following SARS-Cov2 infection 一名 SARS-Cov2 感染后长期神经心理并发症患者的脑电图异常
IF 0.7
Case Reports in Neurology Pub Date : 2023-12-05 DOI: 10.1159/000535241
D. Benis, P. Voruz, S. C. Chiuvé, Valentina Garibotto, F. Assal, P. Krack, J. Péron, Vanessa Fleury
{"title":"Electroencephalographic abnormalities in a patient suffering from long-term neuropsychological complications following SARS-Cov2 infection","authors":"D. Benis, P. Voruz, S. C. Chiuvé, Valentina Garibotto, F. Assal, P. Krack, J. Péron, Vanessa Fleury","doi":"10.1159/000535241","DOIUrl":"https://doi.org/10.1159/000535241","url":null,"abstract":"Introduction\u0000Emotional apathy has recently been identified as a common symptom of long COVID. While recent meta-analyses have demonstrated generalized EEG slowing with the emergence of delta rhythms in patients hospitalized for severe SARS-Cov2 infection, no EEG study or dopamine transporter scintigraphy (DaTSCAN) have been performed in patients with long COVID presenting with apathy. The objective of this case report was to explore the pathophysiology of neuropsychological symptoms in long COVID. \u0000Case presentation\u0000A 47-year-old patient who developed a long COVID with prominent apathy following an initially clinically mild SARS-Cov2 infection, underwent neuropsychological assessment, cerebral MRI, DaTSCAN, and resting-state high-density EEG seven months after SARS-Cov2 infection. The EEG data were compared to those of 21 healthy participants. The patient presented with apathy, cognitive difficulties with dysexecutive syndrome, moderate attentional and verbal episodic memory disturbances, and resolution of pre-morbid mild gaming disorder, mild mood disturbances, and sleep disturbances. His MRI and DaTSCAN were unremarkable. EEG revealed a complex pattern of oscillatory abnormalities compared to the control group, with a strong increase in whole-scalp delta and beta band activity, as well as a decrease in alpha band activity. Overall, these effects were more prominent in the frontal-central-temporal region. Conclusion\u0000These results suggest widespread changes in EEG oscillatory patterns in a patient with long Covid characterized by neuropsychological complications with prominent apathy. Despite the inherent limitations of a case report, these results suggest dysfunction in the cortical networks involved in motivation and emotion.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"81 10","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138598209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anesthetic management with propofol in a patient with Rasmussen's encephalitis complicated by intractable partial-onset epileptic seizures: a case report 异丙酚麻醉治疗拉斯穆森脑炎合并难治性部分性癫痫发作1例
Case Reports in Neurology Pub Date : 2023-10-26 DOI: 10.1159/000534754
Mai Akazawa, Guoshan Yan, Rina Hirai, Hirotoshi Kitagawa
{"title":"Anesthetic management with propofol in a patient with Rasmussen's encephalitis complicated by intractable partial-onset epileptic seizures: a case report","authors":"Mai Akazawa, Guoshan Yan, Rina Hirai, Hirotoshi Kitagawa","doi":"10.1159/000534754","DOIUrl":"https://doi.org/10.1159/000534754","url":null,"abstract":"Introduction: Rasmussen's encephalitis (RE) is a progressive and chronic ailment characterized by drug-resistant epileptic seizures. RE is uncommon, and no documented accounts of its anesthetic management exist. Anesthetic management without causing epileptic seizures is important in RE. Here, we present a case of safe anesthetic management in a pediatric patient with RE. Case presentation: A 7-year-old boy who was diagnosed with RE at the age of 6 years was scheduled for supernumerary tooth extraction under general anesthesia. The patient was being treated with prednisolone, sodium valproate, zonisamide, lacosamide, and famotidine. Despite receiving antiepileptic therapy, the patient experienced partial epileptic seizures several times per week. The seizures presented as numbness in his right hand and progressed to tonic-clonic seizures affecting the right side of his body. On the day of the surgical procedure, the patient was administered regular doses of antiepileptic drugs and prednisolone. Anesthesia was induced and maintained using a combination of propofol, remifentanil, and rocuronium. The surgical procedure was successfully performed, and the patient awakened smoothly from anesthesia. No epileptic seizures were observed intra- or post-operatively. Conclusion: RE typically presents with drug-resistant seizures and the initial symptoms are usually refractory partial seizures. Propofol is well-established as a treatment option for refractory status epilepticus, and it reduces the frequency of spikes in patients with partial epilepsy. In this case, general anesthesia without epileptic seizures was achieved using propofol.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"27 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Baló Concentric Sclerosis Mimicking Encephalitis with Seizures and Progressive Aphasia in a 26-Year-Old Woman: A Challenging Diagnostic Dilemma. 一名26岁女性的类似脑炎的Baló同心性硬化症伴癫痫发作和进行性失语症:一个具有挑战性的诊断难题。
IF 0.7
Case Reports in Neurology Pub Date : 2023-10-06 eCollection Date: 2023-01-01 DOI: 10.1159/000534358
Nexhmedin Shala, Ilir Tolaj, Fisnik Jashari, Edita Malazogu, Argjend Shala, Gentiant Bajraktari, Ilir Ahmetgjekaj, Shemsedin Dreshaj
{"title":"Baló Concentric Sclerosis Mimicking Encephalitis with Seizures and Progressive Aphasia in a 26-Year-Old Woman: A Challenging Diagnostic Dilemma.","authors":"Nexhmedin Shala, Ilir Tolaj, Fisnik Jashari, Edita Malazogu, Argjend Shala, Gentiant Bajraktari, Ilir Ahmetgjekaj, Shemsedin Dreshaj","doi":"10.1159/000534358","DOIUrl":"10.1159/000534358","url":null,"abstract":"<p><strong>Introduction: </strong>Baló's concentric sclerosis (BCS) is a rare subtype of multiple sclerosis characterized by inflammatory demyelination within the central nervous system.</p><p><strong>Case presentation: </strong>This case report presents a challenging diagnostic scenario involving a 26-year-old woman diagnosed with BCS. Despite treatment, her condition did not ameliorate, and magnetic resonance imaging (MRI) findings remained unchanged. A subsequent stereotactic biopsy revealed tumefactive Balo disease, highlighting the intricate diagnostic and therapeutic issues surrounding BCS.</p><p><strong>Conclusion: </strong>The juxtacortical location of the BCS lesion, as observed in our case, suggests an unfavourable prognosis due to treatment-resistant seizures.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"227-232"},"PeriodicalIF":0.7,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71421026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Cardioembolic Spinal Stroke in a Young Female: Case Report. 一例罕见的年轻女性心脏栓塞性脊髓卒中病例报告。
IF 0.7
Case Reports in Neurology Pub Date : 2023-09-26 eCollection Date: 2023-01-01 DOI: 10.1159/000531779
Rom Mendel, Irina Tsirkin, Eugene Soikher, Salo Haratz
{"title":"A Rare Case of Cardioembolic Spinal Stroke in a Young Female: Case Report.","authors":"Rom Mendel, Irina Tsirkin, Eugene Soikher, Salo Haratz","doi":"10.1159/000531779","DOIUrl":"10.1159/000531779","url":null,"abstract":"<p><p>Spinal cord infarction (SCI) is a rare neurovascular disorder often presented with acute spinal cord syndrome. The diagnosis is generally made clinically, with appropriate neuroimaging to confirm the diagnosis and exclude other causes. We present an unusual case of a 48-year-old woman with no relevant past medical history, admitted with acute paraparesis and a spinal cord infarct on magnetic resonance imaging. A thorough investigation revealed asymptomatic unknown heart failure secondary to hypertrophic cardiomyopathy, suggestive of a cardioembolic etiology. The patient was treated with anticoagulation and improved significantly with physical rehabilitation.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"222-226"},"PeriodicalIF":0.7,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71410882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brait-Fahn-Schwartz Disease: A Unique Co-Occurrence of Parkinson's Disease and Amyotrophic Lateral Sclerosis. Brait-Fahn-Schwartz病:帕金森病和肌萎缩侧索硬化症的独特合并症。
IF 0.7
Case Reports in Neurology Pub Date : 2023-09-21 eCollection Date: 2023-01-01 DOI: 10.1159/000532092
Ayesha Aslam, Eisham Sarmad, Ahmad Nawaz, Ahsan Numan, Azba Ahmad, Muhammad Aarish Hassan
{"title":"Brait-Fahn-Schwartz Disease: A Unique Co-Occurrence of Parkinson's Disease and Amyotrophic Lateral Sclerosis.","authors":"Ayesha Aslam, Eisham Sarmad, Ahmad Nawaz, Ahsan Numan, Azba Ahmad, Muhammad Aarish Hassan","doi":"10.1159/000532092","DOIUrl":"10.1159/000532092","url":null,"abstract":"<p><p>The Parkinson's disease-amyotrophic lateral sclerosis (ALS) complex typically manifests as levodopa-responsive parkinsonism, followed by ALS. It is extremely rare for Parkinson's disease and ALS to coexist without other neurological disorders. Named after the scientists who first described this overlap of two neurodegenerative conditions, it is referred to as Brait-Fahn-Schwartz disease. Given its variable presentation, increasing rarity, and lack of any diagnostic test, it poses a diagnostic challenge for physicians. We present a case of a 55-year-old Pakistani male experiencing progressive quadriparesis with spastic lower limbs and flaccid upper limbs, in addition to the cardinal features of idiopathic Parkinson's disease. Since there is currently no cure available for either Parkinson's disease or ALS, all available treatment focuses on improving quality of life, which we achieved in our patient. This case is unique in being the first incidence of Parkinson's disease-ALS complex in a novel geographic region such as Pakistan, where genetic testing and cost constraints limit the diagnosis of rare disorders. The coexistence of extrapyramidal symptoms and pyramidal symptoms is uncommon. In such situations, physicians may overlook one group of symptoms, potentially leading to a misdiagnosis. This case highlights the value of a thorough physical examination and electrodiagnostic studies and suggests the association between Parkinson's disease and ALS. This case demonstrates the significance of understanding when Parkinson's disease symptoms start to appear in patients with ALS and the need to start dopaminergic therapy in those who had Parkinson's disease features before ALS to alleviate the suffering of an individual and enhance quality of life.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"207-214"},"PeriodicalIF":0.7,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71410884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcirculation Approach for Matricidal Carotid Cavernous Aneurysm: Not a Good Choice - A Case Report of Unsuccessful Endovascular Treatment of Matricidal Carotid Cavernous Aneurysm. 经循环治疗杀性颈动脉海绵状瘤:不是一个好的选择——一例杀性颈静脉海绵状瘤血管内治疗失败的病例报告。
IF 0.7
Case Reports in Neurology Pub Date : 2023-09-04 eCollection Date: 2023-01-01 DOI: 10.1159/000533832
Norbert Svoboda, Jozef Malik, Frantisek Charvat, David Netuka
{"title":"Transcirculation Approach for Matricidal Carotid Cavernous Aneurysm: Not a Good Choice - A Case Report of Unsuccessful Endovascular Treatment of Matricidal Carotid Cavernous Aneurysm.","authors":"Norbert Svoboda,&nbsp;Jozef Malik,&nbsp;Frantisek Charvat,&nbsp;David Netuka","doi":"10.1159/000533832","DOIUrl":"https://doi.org/10.1159/000533832","url":null,"abstract":"<p><p>Matricidal carotid cavernous aneurysm (CCA) is a rare and dangerous condition. The treatment failure of the endovascular approach like flow diversion, coiling, or stent-coiling is relatively high with considerable morbidity and mortality. The transcirculation approach is an alternative treatment option, but in case of matricidal CCAs, the results are not well documented in the literature. The authors present a complicated case of an unsuccessful transcirculation approach for matricidal CCA finally treated with sacrifice of the parent artery and high-flow bypass.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"215-221"},"PeriodicalIF":0.7,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71410886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Botulinum Toxin-A for the Treatment of Neuropathic Pain after Decompressive Craniotomy in Stroke: Two Cases. 肉毒杆菌毒素A治疗脑卒中开颅减压术后神经性疼痛2例。
IF 0.7
Case Reports in Neurology Pub Date : 2023-08-22 eCollection Date: 2023-01-01 DOI: 10.1159/000532096
Yvonne Teuschl, Christian Bancher, Alexandra Dachenhausen, Karl Matz, Michaela M Pinter
{"title":"Botulinum Toxin-A for the Treatment of Neuropathic Pain after Decompressive Craniotomy in Stroke: Two Cases.","authors":"Yvonne Teuschl, Christian Bancher, Alexandra Dachenhausen, Karl Matz, Michaela M Pinter","doi":"10.1159/000532096","DOIUrl":"10.1159/000532096","url":null,"abstract":"<p><p>Botulinum toxin-A (BoNT-A) is recommended as third-line off-label treatment for the management of neuropathic pain. BoNT-A has been reported as treatment for different neuropathic pain conditions; however, not for neuropathic pain after decompressive craniotomy for stroke. The aim of this retrospective case series is to provide information on safety, the effect, and the application method of BoNT-A in clinical practice for the treatment of neuropathic pain after trepanation. This case series describes 2 patients treated in 2021 at a BoNT outpatient clinic for chronic neuropathic pain at the incisional site after decompressive craniotomy for stroke who were resistant to pain medication. Cases were a 48-year-old woman and a 63-year-old man suffering from chronic neuropathic pain since 3 and 6 years, respectively. They were treated regularly with BoNT-A with a total dose of 100 mouse units of incobotulinumtoxin-A injected into peri-incisional sites of the scalp. Both patients reported subjective decrease in pain frequency (40% and 60%), in pain intensity (60% and 90%), and an increase of quality of life (80%). BoNT-A should be further investigated as treatment for neuropathic pain - especially in underreported conditions such as neuropathic pain after craniotomy in stroke.</p>","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"192-198"},"PeriodicalIF":0.7,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71410883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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