Case Reports in Neurology最新文献_第5页

Recurrent Acute on Chronic Respiratory Failure in Stiff Person Syndrome. 僵硬人综合征中反复急性对慢性呼吸衰竭。

IF 0.7

Case Reports in Neurology Pub Date : 2023-08-22 eCollection Date: 2023-01-01 DOI: 10.1159/000532093

Bhumika Bheemavarapu, Arkaja Singh, Nived Jayaraj Ranjini, Venkata Sai Abhilash Meda, Dhrumil Patil

{"title":"Recurrent Acute on Chronic Respiratory Failure in Stiff Person Syndrome.","authors":"Bhumika Bheemavarapu, Arkaja Singh, Nived Jayaraj Ranjini, Venkata Sai Abhilash Meda, Dhrumil Patil","doi":"10.1159/000532093","DOIUrl":"10.1159/000532093","url":null,"abstract":"Stiff person syndrome (SPS) is an extremely rare disease that presents with episodic painful muscle spasms and progressive muscle rigidity. Recent evidence suggests that SPS can rarely manifest with life-threatening respiratory complications. However, the pathophysiology behind respiratory failure in SPS is still not clearly understood. Here, we explored an extremely rare case of a 36-year-old African-American female with SPS presenting with multiple episodes of respiratory failure events for the past 9 years. She had an in-situ tracheostomy and was admitted to the hospital for tracheostomy evaluation and decannulation. 11 years ago she initially presented with gait abnormalities, stiffness, and spastic episodes. She was diagnosed 1 year later with SPS after detecting elevated anti-glutamic acid decarboxylase antibody levels in her blood. Through this report, we were able to follow a very rare case of SPS that presented with multiple episodes of respiratory failure. We pointed out the importance of early start and regular administration of diazepam, baclofen, and IVIg in not only controlling the symptoms and progression of the disease but also in preventing further respiratory failure and possible sudden death.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"187-191"},"PeriodicalIF":0.7,"publicationDate":"2023-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601654/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71410885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prodromal Dementia with Lewy Bodies: A Case Series of the 3 Prodromal Types from Clinical Practice. 路易体前驱性痴呆：临床实践中的3种前驱型病例系列。

IF 0.7

Case Reports in Neurology Pub Date : 2023-08-11 eCollection Date: 2023-01-01 DOI: 10.1159/000533378

Tracy Tholanikunnel, Benjamin Chapin, Melissa Armstrong

引用次数: 0

Symmetric Ascending Paralysis Secondary to West Nile Virus. 继发于西尼罗河病毒的对称性上行性麻痹。

IF 0.7

Case Reports in Neurology Pub Date : 2023-07-13 eCollection Date: 2023-01-01 DOI: 10.1159/000529120

Alex Ashkin, Nicole Saccone, Jose Valle, Mark Rasnake

引用次数: 0

Encephalitis as a Clinical Manifestation of COVID-19: A Case Series. 作为 COVID-19 临床表现的脑炎：病例系列。

IF 0.7

Case Reports in Neurology Pub Date : 2023-06-15 eCollection Date: 2023-01-01 DOI: 10.1159/000530926

Muhammad Hammad Sharif, Madeeha Khaleeque, Asad Ali Khan, Muhammad Hassan Jan, Atif Ahmed, Nida Latif, Abdul Qadir, Muhammad Hanif, Amjid Iqbal

{"title":"Encephalitis as a Clinical Manifestation of COVID-19: A Case Series.","authors":"Muhammad Hammad Sharif, Madeeha Khaleeque, Asad Ali Khan, Muhammad Hassan Jan, Atif Ahmed, Nida Latif, Abdul Qadir, Muhammad Hanif, Amjid Iqbal","doi":"10.1159/000530926","DOIUrl":"10.1159/000530926","url":null,"abstract":"COVID-19 is a novel virus which causes a variety of clinical manifestations in the body, some of which are yet to be discovered. The main aim of our study is to highlight the neurological manifestations of COVID-19 as it is still new to the medical world, and to emphasize the fact that the physicians have to be wary of the possibility that patients affected by COVID-19 can present with encephalitis. Only a few studies are available so far regarding the neurological manifestations of this novel virus which highlights the need for this study. We present a case series of 4 patients who were found to have COVID-19 encephalitis. There is still no disease-defining test for diagnosis so the mainstay of diagnosis is exclusion of all the common causes of encephalitis. Brain magnetic resonance imaging and cerebrospinal fluid analysis performs an ancillary in the diagnostic tools. Our study also supports the use of IV tocilizumab (4-8 mg/kg) and IV methylprednisolone (0.5-2 mg/kg) as possible treatment options with good results, as the patients described in our case series responded well to these medications.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"131-139"},"PeriodicalIF":0.7,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b7/95/crn-2023-0015-0001-530926.PMC10359675.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10221356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thirty-Year Follow-Up of Early Onset Amyotrophic Lateral Sclerosis with a Pathogenic Variant in SPTLC1. 早发肌萎缩性侧索硬化症伴SPTLC1致病变异的30年随访。

IF 0.7

Case Reports in Neurology Pub Date : 2023-06-12 eCollection Date: 2023-01-01 DOI: 10.1159/000530974

Aparna Ajjarapu, Shawna M E Feely, Michael E Shy, Christina Trout, Stephan Zuchner, Steven A Moore, Katherine D Mathews

引用次数: 0

Cytotoxic Lesions beyond the Corpus Callosum Following Acute Meningoencephalitis and Mycoplasma Pneumoniae Infection: A Case Report and Literature Review. 急性脑膜脑炎和肺炎支原体感染后胼胝体外的细胞毒性病变：病例报告和文献综述。

IF 0.7

Case Reports in Neurology Pub Date : 2023-06-12 eCollection Date: 2023-01-01 DOI: 10.1159/000530944

Kuan-Hsien Lu, Te-Chang Wu, Poh-Shiow Yeh

{"title":"Cytotoxic Lesions beyond the Corpus Callosum Following Acute Meningoencephalitis and Mycoplasma Pneumoniae Infection: A Case Report and Literature Review.","authors":"Kuan-Hsien Lu, Te-Chang Wu, Poh-Shiow Yeh","doi":"10.1159/000530944","DOIUrl":"10.1159/000530944","url":null,"abstract":"Cytotoxic lesions of the corpus callosum (CLOCCs) are secondary lesions associated with a variety of clinical causes. The presence of a small and reversible lesion in the splenium of corpus callosum with restricted diffusion on cranial magnetic resonance imaging is the defining feature. The clinical-radiological manifestations have been documented as mild and reversible. Severer presentations were scarcely reported. In this report, we described a 25-year-old man with preceding fever, worsening somnolence, and convulsions. He was diagnosed with acute meningoencephalitis and Mycoplasma pneumoniae infection after workups. After medical treatments, he had neurological deterioration and progressing CLOCCs from a small oval lesion in the center of splenium extending to the whole corpus callosum and bilaterally adjacent white matter. The patient received intravenous methylprednisolone and immunoglobulin successively, and his neurological conditions improved. The CLOCCs, not always mild and reversible, could present with severe clinicoradiological features.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"15 1","pages":"113-119"},"PeriodicalIF":0.7,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/06/crn-2023-0015-0001-530944.PMC10368104.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10241005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Inverse Lhermitte Phenomenon Suggests Nitrous Oxide-Induced Myelopathy: Case Report and Review of the Literature. 逆勒米特现象表明一氧化二氮诱发了脊髓病：病例报告与文献综述。

IF 0.7

Case Reports in Neurology Pub Date : 2023-06-08 eCollection Date: 2023-01-01 DOI: 10.1159/000529325

Sonali Sharma, Michael Benatar, Steven Herskovitz, Volkan Granit

引用次数: 0

Isoniazid-Induced Psychosis in a Patient with Pulmonary Tuberculosis: A Case Report. 肺结核患者的异烟肼诱发精神病：病例报告。

IF 0.7

Case Reports in Neurology Pub Date : 2023-06-08 eCollection Date: 2023-01-01 DOI: 10.1159/000530779

Shreshth Khanna, Suchita Pant, Harsh Khanna

引用次数: 0

Can Growth Hormone Lead to a Faster Recovery from Guillain-Barré Syndrome? Case Report of the First Therapeutic Use in One Patient. 生长激素能使格林-巴罗综合征更快恢复吗?1例患者首次治疗用药病例报告

IF 0.7

Case Reports in Neurology Pub Date : 2023-06-05 eCollection Date: 2023-01-01 DOI: 10.1159/000530065

Felix Amereller, Jochen Schopohl, Sylvère Störmann, Katharina Schilbach, Martin Bidlingmaier, Martin Fischer, Peter Rieckmann, Philipp Gulde

{"title":"Can Growth Hormone Lead to a Faster Recovery from Guillain-Barré Syndrome? Case Report of the First Therapeutic Use in One Patient.","authors":"Felix Amereller, Jochen Schopohl, Sylvère Störmann, Katharina Schilbach, Martin Bidlingmaier, Martin Fischer, Peter Rieckmann, Philipp Gulde","doi":"10.1159/000530065","DOIUrl":"10.1159/000530065","url":null,"abstract":"Although the prognosis in Guillain-Barré syndrome (GBS) is generally good, protracted and incomplete courses of recovery can be a heavy burden. Animal studies suggest growth hormone (GH) treatment could stimulate myelin repair and thus accelerate functional recovery in acute polyneuropathy. We report on the first use of GH in GBS. Our objective was to monitor safety and tolerability as well as to evaluate the effect of an off-label GH therapy during recovery from GBS in 1 patient. A 28-year-old male with flaccid tetraparesis caused by pure motor GBS was treated off-label with GH (1 mg/day) for 10 weeks. Muscle strength was measured regularly before, during, and after the treatment over a total span of 330 days. Serum levels of IGF-I were assessed before, during, and after GH treatment. Changes in strength gain were used as the main parameter of efficacy. No side effects of GH treatment were observed. Serum IGF-I increased from 177 ng/mL at baseline to an average of 342 ng/mL (normal range 78-270 ng/mL) during treatment. Prior to GH administration, strength (R2 = 0.99, p < 0.01) was associated with time, representing the natural course of recovery. During GH treatment, the slope of strength gain increased (Glass' ∆ = 1.08, p < 0.01). The association between alterations of strength gain and IGF-I serum levels reached trend level (R2 = 0.36, p = 0.09). In this single case, GH treatment seemed to be associated with faster muscular strength gain. Controlled studies are needed in order to establish GH as a potential therapeutic approach in motor GBS.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"1 1","pages":"163-171"},"PeriodicalIF":0.7,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601620/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41339793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contraversive Ocular Tilt Reaction with Contralesional Pseudo-Abducens Palsy in a Patient with Thalamomesencephalic Stroke. 一名丘脑中风患者的对抗性眼球后仰反应和对抗性假性视神经麻痹

IF 0.7

Case Reports in Neurology Pub Date : 2023-06-01 eCollection Date: 2023-01-01 DOI: 10.1159/000531085

Mohamad Fateh Dabbagh, Lina Okar, Dirk Deleu, Boulenouar Mesraoua

引用次数: 0