Case Reports in Neurology最新文献

Neurological Immune-Related Adverse Events in Patients Treated with Anti-Programmed Death 1 Agent, Pembrolizumab: A Case Series. 抗程序性死亡1药物（Pembrolizumab）治疗患者的神经免疫相关不良事件：一个病例系列

IF 0.6

Case Reports in Neurology Pub Date : 2025-06-19 eCollection Date: 2025-01-01 DOI: 10.1159/000547004

Sepehr Khosravi, Tara Khoeini, Fateme Rahattalab, Bahram Haghi Ashtiani

{"title":"Neurological Immune-Related Adverse Events in Patients Treated with Anti-Programmed Death 1 Agent, Pembrolizumab: A Case Series.","authors":"Sepehr Khosravi, Tara Khoeini, Fateme Rahattalab, Bahram Haghi Ashtiani","doi":"10.1159/000547004","DOIUrl":"10.1159/000547004","url":null,"abstract":"Background: This case series highlights the various clinical manifestations of pembrolizumab-induced neurological adverse events, offering insights into the spectrum of immune-related neurological adverse events associated with immune checkpoint inhibitor (ICI) therapy.Case presentation: We present 5 patients who received pembrolizumab as a part of their treatment. They exhibited a variety of clinical manifestations, which included central nervous system involvement and necrotizing myopathy, each responding differently to therapeutic interventions. Among the participants, there were two cases of myopathy, one case of demyelinating polyneuropathy, one individual whose myasthenia gravis had worsened, and 1 patient diagnosed with encephalitis. The patients experienced symptoms with varying degrees of severity, leading to different responses in their clinical treatment, and 1 patient ultimately passed away due to complications.Conclusion: Neurological immune-related adverse effects (n-irAEs) are rare, and their identification poses a challenge due to their complexity and the presence of underlying autoimmune and paraneoplastic disorders. The expected prognosis for n-irAEs is unclear, presenting a range of complete recovery rates and differing mortality outcomes. The increased frequency of ICI usage increases the probability of an immune response, necessitating healthcare professionals to identify new symptoms in immunotherapy patients. Side effects differ from conventional chemotherapy and necessitate different therapeutic approaches.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"94-101"},"PeriodicalIF":0.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges in the Diagnosis and Care of Tuberous Sclerosis Complex in Resource-Limited Settings: A Case Report from Tanzania. 在资源有限的情况下结节性硬化症的诊断和护理的挑战：来自坦桑尼亚的病例报告。

IF 0.6

Case Reports in Neurology Pub Date : 2025-06-10 eCollection Date: 2025-01-01 DOI: 10.1159/000546098

Basil Tumaini, John Calori, Ernest Ibenzi

{"title":"Challenges in the Diagnosis and Care of Tuberous Sclerosis Complex in Resource-Limited Settings: A Case Report from Tanzania.","authors":"Basil Tumaini, John Calori, Ernest Ibenzi","doi":"10.1159/000546098","DOIUrl":"10.1159/000546098","url":null,"abstract":"Introduction: Tuberous sclerosis complex (TSC) is a rare, multisystem genetic disorder caused by mutations in the TSC1 or TSC2 genes, resulting in dysregulation of the mTOR pathway. Clinical manifestations include epilepsy, cutaneous lesions, and hamartomas in various organs, presenting diagnostic challenges, especially in resource-limited settings. In low- and middle-income countries (LMICs), barriers such as lack of access to genetic testing, advanced imaging, and targeted therapies contribute to underdiagnosis and delayed care.Case presentation: We present a 22-year-old male from rural Tanzania with a 20-year history of intractable, treatment-refractory epilepsy. He also exhibited cutaneous findings, including facial angiofibromas, ash-leaf macules, and a shagreen patch. Brain imaging revealed subependymal nodules, and renal imaging identified angiomyolipomas. Despite the absence of genetic testing, a clinical diagnosis of TSC was made. The patient's condition was further complicated by aspiration pneumonia. Management included anticonvulsant therapy, antibiotics, and supportive care. Multisystem evaluation revealed cystic lung disease and renal involvement, underscoring the need for comprehensive follow-up. This case highlights the diagnostic reliance on clinical expertise and basic imaging in resource-limited settings.Conclusion: This report emphasizes the importance of clinical recognition and multidisciplinary management of TSC in resource-constrained settings. Strengthening healthcare infrastructure, raising awareness, and fostering collaborations to enhance access to genetic testing and mTOR-targeted therapies are critical to improving outcomes for TSC patients in LMICs. The lessons from this case underscore the global relevance of addressing healthcare disparities in rare genetic disorders.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"79-87"},"PeriodicalIF":0.6,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12252377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144625447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subclavian Artery-Internal Carotid Artery Bypass Using a Radial Artery Graft for Common Carotid Artery Occlusion with Immediate Improvement of Cognitive Function: A Case Report. 锁骨下动脉-颈内动脉搭桥桡动脉移植治疗颈总动脉闭塞，认知功能即刻改善1例报告。

IF 0.6

Case Reports in Neurology Pub Date : 2025-06-05 eCollection Date: 2025-01-01 DOI: 10.1159/000546580

Kazuya Morita, Tomoya Kamide, Riho Nakajima, Seiya Kudou, Taishi Tsutsui, Kouichi Misaki, Mitsutoshi Nakada

{"title":"Subclavian Artery-Internal Carotid Artery Bypass Using a Radial Artery Graft for Common Carotid Artery Occlusion with Immediate Improvement of Cognitive Function: A Case Report.","authors":"Kazuya Morita, Tomoya Kamide, Riho Nakajima, Seiya Kudou, Taishi Tsutsui, Kouichi Misaki, Mitsutoshi Nakada","doi":"10.1159/000546580","DOIUrl":"10.1159/000546580","url":null,"abstract":"Introduction: Although rare, common carotid artery occlusion (CCAO) causes ischemic neurological dysfunction, which can be treated by revascularization. Although several bypass approaches for CCAO have been suggested, no consensus on the surgical revascularization approach and its functional outcome have been reached. Herein, we present a case of Rile's type 1A CCAO in which a subclavian artery (SclA)-internal carotid artery (ICA) bypass using a radial artery graft (RAG) resulted in immediate recovery of cognitive function and successfully prevented ischemic stroke.Case description: A 58-year-old man presented with recurrent episodes of right-sided weakness. Brain magnetic resonance imaging revealed multiple cerebral infarcts. Digital subtraction angiography confirmed left CCAO and no anterograde blood flow in the left ICA and ipsilateral external carotid artery. A bypass was performed from the left SclA to the left cervical ICA using a left RAG, and supraclavicular anastomosis between the SclA and ICA was performed without graft-vessel kinking. Postoperatively, no neurological deficits were observed, and his cognitive function was successfully improved.Conclusion: SclA-ICA bypass using an RAG can be a reasonable treatment option for CCAO. CCAO revascularization can prevent ischemic stroke and improve cognitive function.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"88-93"},"PeriodicalIF":0.6,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lyme Neuroborreliosis Presenting with Isolated Intracranial Hypertension: A Case Report. 以孤立性颅内高压为表现的莱姆病神经螺旋体病1例。

IF 0.6

Case Reports in Neurology Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI: 10.1159/000546097

Dax Bourcier, Joyce Beshara, Griffin Pauli, Tyler Henry, Michael Peckford, Richard Huntsman, Bashar M Bata, Tobias R Kollmann

{"title":"Lyme Neuroborreliosis Presenting with Isolated Intracranial Hypertension: A Case Report.","authors":"Dax Bourcier, Joyce Beshara, Griffin Pauli, Tyler Henry, Michael Peckford, Richard Huntsman, Bashar M Bata, Tobias R Kollmann","doi":"10.1159/000546097","DOIUrl":"10.1159/000546097","url":null,"abstract":"Background: Lyme borreliosis, a tick-borne illness caused by Borrelia burgdorferi, is increasingly prevalent in Nova Scotia, Canada, which has the highest incidence in North America. While most cases present as early localized disease, approximately 20% develop early disseminated disease, which can include neurological symptoms, an entity called Lyme neuroborreliosis (LNB). This case report describes an unusual LNB presentation with isolated intracranial hypertension (IH).Case presentation: A 6-year-old female presented to our pediatric hospital with binocular horizontal diplopia, headache, fever, malaise, and suspected papilledema 47 days after an embedded tick bite. A diagnosis of Lyme disease had been made 10 days prior in the community based on positive serologies and erythema migrans, but she developed a Jarisch-Herxheimer reaction within 24 h of oral doxycycline, leading to an antibiotic change to amoxicillin. During the hospital admission, an ophthalmological examination revealed papilledema and IH was evidenced by an opening pressure of 36 mm Hg and brain MRI findings. The lumbar puncture revealed pleocytosis and positive cerebrospinal fluid antibodies for Borrelia. The patient was initially treated with 2 days of ceftriaxone, followed by a 12-day outpatient course of doxycycline for LNB. High doses of acetazolamide (500 mg TID) were needed to achieve symptom control. Two months after her hospital discharge, there was resolution of papilledema and the acetazolamide was weaned.Conclusion: This case highlights the importance of considering Lyme disease in the differential diagnosis of IH, particularly in endemic regions. Early recognition, diagnostic workup, and appropriate treatment are crucial for optimal outcomes in LNB.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"72-78"},"PeriodicalIF":0.6,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12187110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed Intracerebral Hemorrhage after Deep Brain Stimulation for Parkinson's Disease. 帕金森病深部脑刺激后迟发性脑出血。

IF 0.6

Case Reports in Neurology Pub Date : 2025-05-06 eCollection Date: 2025-01-01 DOI: 10.1159/000546056

Hana Chudy, Marina Raguž, Petar Marčinković, Valentino Rački, Eliša Papić, Mario Hero, Vladimira Vuletić, Darko Chudy

{"title":"Delayed Intracerebral Hemorrhage after Deep Brain Stimulation for Parkinson's Disease.","authors":"Hana Chudy, Marina Raguž, Petar Marčinković, Valentino Rački, Eliša Papić, Mario Hero, Vladimira Vuletić, Darko Chudy","doi":"10.1159/000546056","DOIUrl":"10.1159/000546056","url":null,"abstract":"Introduction: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a well-established treatment for advanced Parkinson's disease (PD), offering significant symptomatic relief. Although DBS is generally considered safe, it carries risks, including the potential for delayed complications such as intracerebral hemorrhage (ICH).Case presentation: We present a rare case of a 67-year-old male with PD who developed delayed ICH after undergoing bilateral STN DBS. Initially, the patient showed no neurological deficits postoperatively, with imaging confirming correct lead placement and no signs of hemorrhage. However, on the second postoperative day, the patient developed sudden right-sided hemiparesis. A CT scan revealed ICH alongside the left lead. The hemorrhage was managed conservatively, and the patient underwent extensive physical therapy, leading to significant improvement. Over the next 2 weeks, the patient's condition improved, and follow-up CT scans showed complete resolution of the ICH. At this point, the left lead stimulation was initiated, further improving the patient's PD symptoms. This case illustrates the potential for delayed ICH following STN DBS, emphasizing the need for ongoing monitoring and individualized treatment strategies.Conclusion: This case underscores the importance of vigilant postoperative monitoring and individualized management strategies in STN DBS patients. Early detection and appropriate management of complications such as ICH are crucial for minimizing risks and ensuring optimal patient outcomes. The potential for delayed complications highlights the need for continuous follow-up, even in the absence of immediate postoperative issues.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"62-71"},"PeriodicalIF":0.6,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12162119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144282460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trigeminal Neuralgia as a Rare Complication of Idiopathic Intracranial Hypertension. 三叉神经痛是特发性颅内高压的罕见并发症。

IF 0.6

Case Reports in Neurology Pub Date : 2025-04-07 eCollection Date: 2025-01-01 DOI: 10.1159/000544077

Mariana Sarov-Riviere, Claire Ancelet, Ghaidaa Nasser, Jildaz Caroff, Nozar Aghakhani, Christian Denier

{"title":"Trigeminal Neuralgia as a Rare Complication of Idiopathic Intracranial Hypertension.","authors":"Mariana Sarov-Riviere, Claire Ancelet, Ghaidaa Nasser, Jildaz Caroff, Nozar Aghakhani, Christian Denier","doi":"10.1159/000544077","DOIUrl":"https://doi.org/10.1159/000544077","url":null,"abstract":"Introduction: Idiopathic intracranial hypertension (IIH) is a rare cause of chronic headaches. Usually, patients with IIH present headaches and papilledema with no focal neurological signs. Classical MRI findings feature characteristic signs, i.e., dilated perioptic nerves sheath and empty sella turcica. Rarely, cranial nerve palsies existed, especially abducens nerve palsy.Case presentation: We reported herein another rare clinical feature of IIH: trigeminal neuralgia in association with meningocele. This 35-year-old obese woman initially presented with chronic headaches and papilledema. Cerebral MRI showed classical IIH findings. The CSF opening pressure was increased. A treatment coupling acetazolamide and iterative lumbar punctures led to the regression of papilledema, but headaches were difficult to control. Ten years later, while she was lost to follow up and treated with acetazolamide by her general practitioner, she developed extremely painful neuropathic pain in the left trigeminal nerve territory, in association with a recurrence of the chronic headaches. A new MRI showed new bilateral cavum trigeminal meningoceles, predominantly on the left side, associated with an atrophy of the cisternal segment of the left trigeminal nerve. Angio-CT showed transverse sinus stenosis, treated by stenting. After this treatment, IIH symptoms disappeared, while trigeminal neuralgia amplified: a surgical procedure led to its complete disappearance.Conclusion: To our knowledge, this is the first case reported of trigeminal neuralgia associated with meningocele formation in IIH. Our case illustrates the great efficacy of venous stenting in IIH, and one may wonder whether earlier stenting could have avoided the subsequent development of meningoceles and subsequent neuralgia.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"57-61"},"PeriodicalIF":0.6,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seronegative Autoimmune Encephalomyelitis with Area Postrema Symptoms. 血清阴性自身免疫性脑脊髓炎伴区域后发症状。

IF 0.6

Case Reports in Neurology Pub Date : 2025-03-26 eCollection Date: 2025-01-01 DOI: 10.1159/000545402

David Andrew Prentice, Ravi Ambati, Lay K Kho, Thomas Jenkins, Paul M Parizel

{"title":"Seronegative Autoimmune Encephalomyelitis with Area Postrema Symptoms.","authors":"David Andrew Prentice, Ravi Ambati, Lay K Kho, Thomas Jenkins, Paul M Parizel","doi":"10.1159/000545402","DOIUrl":"https://doi.org/10.1159/000545402","url":null,"abstract":"Introduction: Patients presenting with encephalopathy and longitudinally extensive myelitis pose a significant diagnostic challenge. Area postrema-related symptoms, such as intractable hiccoughs, can aid in narrowing the differential diagnosis. Neuromyelitis optica spectrum disorders and glial fibrillary acidic protein (GFAP) autoimmune encephalitis are known causes; however, some cases remain seronegative, suggesting the presence of unidentified autoantibodies or immune targets.Case presentation: A previously healthy man in his 70s presented with headache, fever, and confusion, followed by a seizure and persistent hiccoughs. MRI revealed brainstem involvement and extensive transverse myelitis. Cerebrospinal fluid (CSF) analysis showed inflammatory features, but testing for AQP4, MOG, and GFAP antibodies was initially negative. He was treated with intravenous corticosteroids and plasma exchange, after which serum GFAP-IgG was weakly positive, though CSF remained negative. His condition improved with immunotherapy, but significant lower limb weakness persisted. Based on clinical and radiological findings, we hypothesize that tanycytes - specialized glial cells in the area postrema - may be an additional immune target in GFAP encephalitis.Conclusion: This case highlights a seronegative encephalomyelitis syndrome with area postrema involvement, possibly implicating glial cells beyond astrocytes. Further studies are needed to explore the role of tanycytes in autoimmune neuroinflammation.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"50-56"},"PeriodicalIF":0.6,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058113/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe Late-Onset Neutropenia in a Pregnant Patient with Multiple Sclerosis after Ocrelizumab. Ocrelizumab治疗多发性硬化症妊娠患者的严重晚发性中性粒细胞减少

IF 0.6

Case Reports in Neurology Pub Date : 2025-03-26 eCollection Date: 2025-01-01 DOI: 10.1159/000544749

Casey J Fealko, Morgan N Rolon-Newton, Marisa J L Aitken, Scott D Gitlin

引用次数: 0

New-Onset Progressive Ataxia in a 66-Year-Old Woman with Longstanding Parkinson's Disease: A Case Report. 66岁女性长期帕金森病新发进行性共济失调1例报告

IF 0.6

Case Reports in Neurology Pub Date : 2025-03-24 eCollection Date: 2025-01-01 DOI: 10.1159/000545411

Lukas Gattermeyer-Kell, Petra Katschnig-Winter, Mariella Kögl, Petra Schwingenschuh

{"title":"New-Onset Progressive Ataxia in a 66-Year-Old Woman with Longstanding Parkinson's Disease: A Case Report.","authors":"Lukas Gattermeyer-Kell, Petra Katschnig-Winter, Mariella Kögl, Petra Schwingenschuh","doi":"10.1159/000545411","DOIUrl":"https://doi.org/10.1159/000545411","url":null,"abstract":"Introduction: Parkinson's disease (PD) is a common neurodegenerative disorder, and its diagnosis remains a clinical one. Hence, the emergence of new symptoms warrants consideration of a new diagnostic work-up even at later disease stages. Important differential diagnoses include atypical or symptomatic parkinsonism, like multiple system atrophy, normal pressure hydrocephalus, or rarely, superficial siderosis (SS).Case presentation: A 66-year-old woman with longstanding PD presented to our clinic with a 4-year history of progressive ataxia and gait impairment. The emergence of a new symptom (ataxia) prompted us to conduct a new, broad diagnostic work-up. Clinical examination revealed both parkinsonian (hypomimia, dyskinesias, right dominant bradykinesia and rigidity, intermittent resting tremor) and cerebellar signs (scanning dysarthria, gaze-evoked nystagmus, severe ataxia of extremities and gait). No signs or symptoms of autonomic dysfunction were present. Magnetic resonance imaging of brain and spine showed extensive hemosiderin depositions and ventral intraspinal fluid collection, establishing a diagnosis of SS. No apparent dural leak was detected in cerebrospinal fluid scintigraphy. The patient was treated with epidural blood patch.Conclusion: The occurrence of new symptoms in PD, especially \"red flags\" or exclusion criteria, calls for a repeated diagnostic work-up to exclude potentially treatable causes of parkinsonism. While SS has been reported as a cause of symptomatic parkinsonism, we favor a diagnosis of idiopathic PD and comorbid SS in this case. This case report highlights the clinical importance of diagnostic criteria in differentiating PD from atypical parkinsonian disorders or symptomatic parkinsonism as well as signs and symptoms, pathophysiological aspects, and treatment of SS.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"41-49"},"PeriodicalIF":0.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Form of Reflex Epilepsy: Eating Epilepsy - A Case Report. 一种罕见的反射性癫痫：进食性癫痫1例报告。

IF 0.6

Case Reports in Neurology Pub Date : 2025-03-04 eCollection Date: 2025-01-01 DOI: 10.1159/000545067

Cem Direybatoğulları, Mehmet Fevzi Öztekin

{"title":"A Rare Form of Reflex Epilepsy: Eating Epilepsy - A Case Report.","authors":"Cem Direybatoğulları, Mehmet Fevzi Öztekin","doi":"10.1159/000545067","DOIUrl":"10.1159/000545067","url":null,"abstract":"Introduction: Reflex epilepsies are rare syndromes where seizures are triggered by particular stimuli or activities that may be motor, sensory, or cognitive in nature. Eating-induced seizures are an uncommon presentation of reflex epilepsy. Many etiologies, including genetics, ethnicity, and specific foods and eating behaviors, are linked to eating epilepsy.Case presentation: In this case report, a 55-year-old man who was admitted to the neurology clinic with epileptic seizures that occurred many times after spicy meals is presented. His neurological examination and metabolic values were normal. MRI showed nonspecific white matter changes. An interictal active epileptic focus was detected in the left temporal region in interictal EEG. The patient was started on valproic acid treatment at 1,000 mg/day. Anti-seizure treatment controlled the seizures and normalized the EEG abnormalities.Conclusion: In this case report, it is emphasized that eating epilepsy should be considered in patients with a history of seizures induced with eating, and the diagnosis and treatment process of eating epilepsy is also mentioned.","PeriodicalId":9639,"journal":{"name":"Case Reports in Neurology","volume":"17 1","pages":"31-35"},"PeriodicalIF":0.6,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0