Case Reports in Gastroenterology最新文献_第9页

Upadacitinib Was Administered as a Sequential Salvage Therapy for Acute Severe Ulcerative Colitis: A Case Report. Upadacitinib作为急性重度溃疡性结肠炎的序贯挽救治疗：1例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-12-23 eCollection Date: 2025-01-01 DOI: 10.1159/000542711

David Huynh, Myat Myat Khaing, Richard Gareth Fernandes, Reuben Malloy, Lei Lin, Robert Gilmore, Nicole Walker, Emi Khoo, Jakob Begun

{"title":"Upadacitinib Was Administered as a Sequential Salvage Therapy for Acute Severe Ulcerative Colitis: A Case Report.","authors":"David Huynh, Myat Myat Khaing, Richard Gareth Fernandes, Reuben Malloy, Lei Lin, Robert Gilmore, Nicole Walker, Emi Khoo, Jakob Begun","doi":"10.1159/000542711","DOIUrl":"10.1159/000542711","url":null,"abstract":"Introduction: Acute severe ulcerative colitis (ASUC) represents a medical emergency associated with high mortality and morbidity. While corticosteroids are the primary treatment, cases that are unresponsive often require rescue therapy with either infliximab or cyclosporine to reduce the rate of colectomy. Janus kinase inhibitors, such as tofacitinib and upadacitinib, are a highly efficacious therapy with rapid induction of clinical response in moderate to severe ulcerative colitis (UC). Limited data are available on its use on ASUC. We present the first case utilizing upadacitinib as sequential medical rescue therapy in ASUC as well as intestinal ultrasound as a useful tool for disease and response monitoring.Case presentation: A 69-year-old female who presented with corticosteroid-refractory ASUC partially responded to dose-intensified infliximab and finally achieved clinical remission with upadacitinib. This resulted in swift clinical remission and significant improvement in her mucosal inflammation on intestinal ultrasound.Conclusion: This successful intervention not only avoided colectomy but demonstrated sustained clinical and sonographic remission 16 weeks of post-treatment. Upadacitinib, with its rapid action and efficacy, shows promise in ASUC and should be supported by registration trials and real-world studies. Despite successful outcomes in this case, further validation and long-term data are necessary.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"1-6"},"PeriodicalIF":0.5,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endovascular Management of a Portal Vein Pseudoaneurysm following Pancreatoduodenectomy: A Case Report and Review of Literature. 胰十二指肠切除术后门静脉假性动脉瘤的血管内治疗：1例报告及文献复习。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-12-23 eCollection Date: 2025-01-01 DOI: 10.1159/000542585

Jelmer E Oor, Eline Groeneweg, Gijs C Bloemsma, Reinoud P H Bokkers, Joost M Klaase

{"title":"Endovascular Management of a Portal Vein Pseudoaneurysm following Pancreatoduodenectomy: A Case Report and Review of Literature.","authors":"Jelmer E Oor, Eline Groeneweg, Gijs C Bloemsma, Reinoud P H Bokkers, Joost M Klaase","doi":"10.1159/000542585","DOIUrl":"10.1159/000542585","url":null,"abstract":"Introduction: Portal vein pseudoaneurysm is a rare but potential life-threatening complication following pancreatoduodenectomy. We herein report on the successful, minimally invasive treatment of this serious complication.Case presentation: A 68-year-old male patient who had undergone pancreatoduodenectomy with portal vein wedge resection at another facility presented to our department due to persistent bile leakage and intermittent bleeding. Abdominal computed tomography scanning demonstrated a large fluid collection surrounding the pancreatojejunostomy, with an occlusion of the common hepatic artery as well as a portal vein pseudoaneurysm. Treatment was performed by means of a minimally invasive approach, including endovascular portal vein stent placement and percutaneous transhepatic biliary drainage (PTBD) through the dehiscent hepaticojejunostomy. This was followed by the placement of a percutaneous pigtail in the peripancreatic fluid collection for adequate drainage. Antibiotics were administered for a total duration of 6 weeks following stent placement. In the subsequent weeks, the PTBD could be internalized and the pigtail removed, after which patient was discharged. During outpatient visits, a contrast injection through the PTBD confirmed the absence of bile leakage, after which the drain could be removed.Conclusion: This article presents one of the few published cases of portal vein pseudoaneurysm following pancreatoduodenectomy and underscores the vital role of minimally invasive endovascular stent and PTBD placement in managing this rare and potentially lethal complication.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"19 1","pages":"7-13"},"PeriodicalIF":0.5,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11666264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastrointestinal Neuroectodermal Tumor/Extraskeletal Ewing Sarcoma of the Ileum with Ulcerative Colitis. 胃肠道神经外胚层肿瘤/骨骼外尤文氏肉瘤的回肠溃疡性结肠炎。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-12-12 eCollection Date: 2024-01-01 DOI: 10.1159/000542659

Tianyu She, Stephanie Ren, Seymour Katz

引用次数: 0

Acute Gastric Dilatation: A Retrospective Case Series from a Single Institution. 急性胃扩张：来自一家医疗机构的回顾性病例系列。

IF 0.6

Case Reports in Gastroenterology Pub Date : 2024-10-15 eCollection Date: 2024-01-01 DOI: 10.1159/000541516

Lefika Bathobakae, Rammy Bashir, Sophia Venero, Tyler Wilkinson, Ruhin Yuridullah, Yana Cavanagh, Walid Baddoura

{"title":"Acute Gastric Dilatation: A Retrospective Case Series from a Single Institution.","authors":"Lefika Bathobakae, Rammy Bashir, Sophia Venero, Tyler Wilkinson, Ruhin Yuridullah, Yana Cavanagh, Walid Baddoura","doi":"10.1159/000541516","DOIUrl":"10.1159/000541516","url":null,"abstract":"Introduction: Acute gastric dilatation (AGD) is a massive distension of the stomach caused by the accumulation of gas, gastric secretions, or food material. AGD is a radiological diagnosis with no clear etiopathogenesis and is often misdiagnosed owing to a lack of clear diagnostic criteria and physician awareness.Case presentation: In this case series, we describe the clinical presentations and outcomes of 4 patients with AGD. Three (75%) of the patients were female, and one (25%) was male. The patients' ages ranged from 53 to 84 years, with an average age of 73.5 years. Abdominal pain, nausea, and vomiting were the most frequently reported complaints. Two (50%) patients had cancer, one (25%) had an acquired duodenal stenosis, and the fourth patient experienced an ileus.Conclusion: AGD is a surgical emergency with a 50-100% mortality rate; thus, prompt diagnosis and management are crucial. Herein, we describe a case series of AGDs that were diagnosed and managed at our institution. We aim to raise awareness about this fatal yet underrecognized clinical entity.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"18 1","pages":"439-448"},"PeriodicalIF":0.6,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521523/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colonic Fishbone-Induced Perforation Involving a Penile Colorectal Carcinoma: A Case Report. 涉及阴茎结直肠癌的结肠鱼刺诱发穿孔：病例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-09-23 eCollection Date: 2024-01-01 DOI: 10.1159/000541081

Akira Imoto, Yuki Nagata, Yoshinori Shinohara, Hirota Miyazaki, Masanobu Fukumoto, Hidehiro Kitae, Masateru Asada, Masafumi Noda, Kaoru Okada, Akira Asai, Kazuhide Higuchi, Hiroki Nishikawa

{"title":"Colonic Fishbone-Induced Perforation Involving a Penile Colorectal Carcinoma: A Case Report.","authors":"Akira Imoto, Yuki Nagata, Yoshinori Shinohara, Hirota Miyazaki, Masanobu Fukumoto, Hidehiro Kitae, Masateru Asada, Masafumi Noda, Kaoru Okada, Akira Asai, Kazuhide Higuchi, Hiroki Nishikawa","doi":"10.1159/000541081","DOIUrl":"https://doi.org/10.1159/000541081","url":null,"abstract":"Introduction: Fishbone (FB) ingestion is a rare cause of gastrointestinal perforation. Herein, we report a case of FB-induced colonic perforation, in which the presence of a penile colonic carcinoma may have contributed to the development of the perforation.Case presentation: An 83-year-old man was admitted to our hospital with severe abdominal pain during bowel movement. Computed tomography (CT) yielded a diagnosis of sigmoid colonic perforation due to FB and secondary peritonitis. Preoperative endoscopic examination suggested that the perforation was associated with a stalked colon tumor in the vicinity. After undergoing low anterior resection and sigmoid colostomy, the patient is currently doing well.Conclusion: The incidence of FB-induced colorectal-cancer-related perforation is expected to increase in the future owing to an aging society, the increase in the rates of colorectal cancer, and increase in fish consumption. This rare case suggests that preoperative examinations are important and that even relatively small polyps can contribute to gastrointestinal perforation caused by FBs. Older individuals should exercise caution during fish ingestion.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"18 1","pages":"431-438"},"PeriodicalIF":0.5,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum. 勘误。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-08-30 eCollection Date: 2024-01-01 DOI: 10.1159/000540535

引用次数: 0

Endoluminal Vacuum Therapy for the Management of Boerhaave Syndrome: A Case Series. 用于治疗波尔哈韦综合征的腔内真空疗法：病例系列。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-08-28 eCollection Date: 2024-01-01 DOI: 10.1159/000540694

Daniella Soussi, Batool Helmi Ahmad Alharahsheh, Piers Robert Boshier, Jonathan Hoare, Natalie Direkze, Robert Thomas, Christopher John Peters, Sophie Stevens

{"title":"Endoluminal Vacuum Therapy for the Management of Boerhaave Syndrome: A Case Series.","authors":"Daniella Soussi, Batool Helmi Ahmad Alharahsheh, Piers Robert Boshier, Jonathan Hoare, Natalie Direkze, Robert Thomas, Christopher John Peters, Sophie Stevens","doi":"10.1159/000540694","DOIUrl":"https://doi.org/10.1159/000540694","url":null,"abstract":"Introduction: Boerhaave syndrome is a rare condition associated with high morbidity and mortality. Prompt intervention greatly improves outcomes, with surgery traditionally being the mainstay of management. Recent advances in therapeutic endoscopy have led to increasing interest in endoluminal vacuum therapy (EVT), a minimally invasive technique, allowing wound debridement and drainage, encouraging granulation tissue formation. EVT has been associated with positive clinical outcomes, including lower mortality rates compared to surgery and stenting for the management of anastomotic leaks, and to a lesser extent, oesophageal perforations. EVT has been adopted into practice across Europe; however, only few cases have been reported from the UK.Case presentations: We report three cases of Boerhaave syndrome, successfully managed with EVT, using the Eso-SPONGE ® (B.Braun Medical Ltd, Sheffield, UK). EVT involves the placement of a polyurethane sponge into the wound cavity. The cavity is initially assessed, then an overtube is introduced through which the sponge is inserted, and then the overtube is removed. Sponge position is confirmed and adjusted if necessary. The sponge is connected via a trans-nasal drain to continuous negative pressure suction and is changed every 3-5 days. Having been deemed surgically unfit, all 3 patients were referred for EVT. All patients made excellent recovery and were discharged home.Conclusion: EVT is an effective management strategy for surgically unfit Boerhaave syndrome patients. Eso-SPONGE use aided drainage of the septic focus and closure of the defect, leading to complete recovery. Our findings support the existing evidence that EVT is a promising solution for Boerhaave syndrome.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"18 1","pages":"402-411"},"PeriodicalIF":0.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142543903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esophageal Tuberculosis as a Rare Cause of Dysphagia: Case Report. 食道结核是吞咽困难的罕见病因：病例报告。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-08-01 eCollection Date: 2024-01-01 DOI: 10.1159/000540292

Billy Zhao, Hyun Jae Kim, Jessica Farrell, Wei Xiong, Jennifer Telford, Sarvee Moosavi

引用次数: 0

Case Study of a Refractory Idiopathic Peptic Ulcer in Which 24-h Intragastric pH Monitoring Contributed to Its Pathophysiological Analysis. 难治性特发性消化性溃疡病例研究，其中 24 小时胃内 pH 值监测有助于病理生理学分析。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-07-31 eCollection Date: 2024-01-01 DOI: 10.1159/000540185

Tomoyo Iwano, Tsutomu Takeda, Shotaro Oki, Yasuko Uemura, Momoko Yamamoto, Ryota Uchida, Hisanori Utsunomiya, Daiki Abe, Nobuyuki Suzuki, Atsushi Ikeda, Yoichi Akazawa, Kumiko Ueda, Hiroya Ueyama, Mariko Hojo, Akihito Nagahara

{"title":"Case Study of a Refractory Idiopathic Peptic Ulcer in Which 24-h Intragastric pH Monitoring Contributed to Its Pathophysiological Analysis.","authors":"Tomoyo Iwano, Tsutomu Takeda, Shotaro Oki, Yasuko Uemura, Momoko Yamamoto, Ryota Uchida, Hisanori Utsunomiya, Daiki Abe, Nobuyuki Suzuki, Atsushi Ikeda, Yoichi Akazawa, Kumiko Ueda, Hiroya Ueyama, Mariko Hojo, Akihito Nagahara","doi":"10.1159/000540185","DOIUrl":"10.1159/000540185","url":null,"abstract":"Introduction: In recent years, the frequency of idiopathic peptic ulcers (IPUs) has increased. However, the clinicopathological characteristics of IPU have not been fully elucidated and treatment methods for recurrent and refractory cases have not yet been established.Case presentation: A man in his forties complained of epigastric discomfort. Esophagogastroduodenoscopy revealed a gastric ulcer in the lesser curvature of the gastric angle. After Helicobacter pylori was eradicated, the gastric ulcer recurred despite the administration of a potassium competitive acid blocker (PCAB), and a diagnosis of IPU was made. Twenty-four-hour intragastric pH monitoring revealed insufficient gastric acid suppression. Misoprostol was added to the patient's treatment. Subsequently, the ulcer healed and recurrence was not observed.Conclusion: For refractory IPU, the evaluation of pathophysiological function through 24-h gastric pH monitoring may lead to the selection of an appropriate treatment. If a proton pump inhibitor and PCAB do not improve the IPU, combination treatment with misoprostol may be considered as an option.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"18 1","pages":"386-394"},"PeriodicalIF":0.5,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11324263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141981730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuberculosis of the Stomach Mimicking Gastric Submucosal Tumor: Diagnosis by Endoscopic Ultrasound. 模仿胃粘膜下肿瘤的胃结核：通过内窥镜超声诊断。

IF 0.5

Case Reports in Gastroenterology Pub Date : 2024-07-30 eCollection Date: 2024-01-01 DOI: 10.1159/000540293

Hasan Maulahela, Nagita Gianty Annisa, Ari Fahrial Syam, Marini Stephanie, Yayi Dwina Billianti

{"title":"Tuberculosis of the Stomach Mimicking Gastric Submucosal Tumor: Diagnosis by Endoscopic Ultrasound.","authors":"Hasan Maulahela, Nagita Gianty Annisa, Ari Fahrial Syam, Marini Stephanie, Yayi Dwina Billianti","doi":"10.1159/000540293","DOIUrl":"10.1159/000540293","url":null,"abstract":"Introduction: Gastrointestinal tuberculosis (TB), specifically gastric TB, is a rare form of extrapulmonary TB. Diagnosis proves challenging with nonspecific signs and symptoms. In this case report, a 22-year-old male came in with complaints of recurrent hematemesis and melena.Case presentation: We found a submucosal mass with ulceration in the stomach cardia on esophagoduodenoscopy (EGD). The endoscopic ultrasound (EUS) finding was a hypoechoic submucosal lesion with a clear margin; specimens were taken using fine needle aspiration (FNA) for further histopathological examination. The result indicated granuloma of Mycobacterium Tuberculosis in pathology, suggesting that the diagnosis was gastric TB. The patient was then treated with antitubercular therapy regimen for 9 months. The previously documented mass in the stomach cardia was no longer visible on the follow-up endoscopy examination, and the patient was considered cured.Conclusion: This case shows that gastric tuberculosis should be considered in patients with gastrointestinal symptoms, especially those living in TB endemic regions. Endoscopic examinations, such as EGD and EUS, may aid in the diagnosis of gastric tuberculosis.","PeriodicalId":9614,"journal":{"name":"Case Reports in Gastroenterology","volume":"18 1","pages":"379-385"},"PeriodicalIF":0.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11324280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141981735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0