Case Reports in Ophthalmological Medicine最新文献_第3页

Bilateral Subinternal Limiting Membrane Crystalline Deposits Secondary to Terson Syndrome. 继发于特森综合征的双侧内膜下限膜结晶沉积。

IF 0.7

Case Reports in Ophthalmological Medicine Pub Date : 2024-01-17 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8225960

Anfisa Ayalon, Eran Greenbaum, Lily Okrent Smolar, Alexander Rubowitz

{"title":"Bilateral Subinternal Limiting Membrane Crystalline Deposits Secondary to Terson Syndrome.","authors":"Anfisa Ayalon, Eran Greenbaum, Lily Okrent Smolar, Alexander Rubowitz","doi":"10.1155/2024/8225960","DOIUrl":"10.1155/2024/8225960","url":null,"abstract":"Background: We report the case of bilateral, subinternal limiting membrane crystalline deposits in a patient with Terson syndrome, describe the possible pathogenesis, and highlight management. Case Presentation. A 24-year-old male with a history of traumatic massive parenchymal and subdural frontal hemorrhage presented to our clinic seven months after a motor vehicle accident, prolonged hospitalization, and rehabilitation, complaining of decreased vision in both eyes. The Snellen visual acuity was 1/60 in the right eye, and 6/60 in the left eye. Fundus examination showed an organized white vitreous hemorrhage in both eyes with almost no view of the retina. The anterior segments were normal. He underwent a 25-gauge pars plana vitrectomy in both eyes. During the surgery, golden crescent-shaped sediment consisting of small crystals was observed under the internal limiting membrane in both eyes: anterior to the inferior temporal vascular arcade in the right eye and posterior to it in the left eye. Internal limiting membrane (ILM) peeling after staining with ILM-blue dye was performed in the left eye, where the finding involved the macula. One year after the surgery, visual acuity significantly improved to 6/8.5 on the right and 6/6 on the left. Epiretinal membrane formation was observed in the right eye, where ILM peeling was not performed.Conclusion: Subinternal limiting membrane crystalline deposit finding is a rare condition. Consider performing internal limiting membrane peeling and sediment removal in cases with macular involvement. In cases where crystals are concentrated outside of the macula, follow-up may be considered.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2024 ","pages":"8225960"},"PeriodicalIF":0.7,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab 首次使用 Nivolumab 和 Ipilimumab 后的视网膜毒性

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2023-12-21 DOI: 10.1155/2023/9931794

A. Kilani, Efstathios Vounotrypidis, Susanna F. König, Armin Wolf

{"title":"Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab","authors":"A. Kilani, Efstathios Vounotrypidis, Susanna F. König, Armin Wolf","doi":"10.1155/2023/9931794","DOIUrl":"https://doi.org/10.1155/2023/9931794","url":null,"abstract":"Background. To present a rare case of a bilateral immune checkpoint inhibitor- (ICI-) induced photoreceptor injury with a bacillary layer detachment (BALAD) and a dissection of the photoreceptor inner and outer segment, accompanied by ICI-induced Vogt-Koyanagi-Harada- (VKH-) like uveitis after initial administration of nivolumab and ipilimumab. Case Presentation. A 52-year-old female with metastatic malignant cutaneous melanoma experiencing bilateral progressive visual acuity reduction, after treatment initiation with 1 mg/kg nivolumab and 3 mg/kg ipilimumab two weeks prior symptom onset. An extensive laboratory workup, including uveitis workup, onconeuronal and retinal antibodies, ruled out a paraneoplastic autoimmune disorder and a granulomatous disease. Furthermore, a B-scan was performed to exclude a posterior scleritis. Ensuing temporary treatment discontinuation of nivolumab and complete discontinuation of ipilimumab, treatment with high-dose systemic steroids was initiated, which resulted in alleviation of her symptoms and stability of ocular findings. Conclusions. ICIs can induce significant ocular side effects. As ocular inflammation can be well controlled using systemic steroids, treatment with ICIs can be continued whenever possible, in particular, if there is a good treatment response of the systemic malignancy.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"140 7","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138953299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

XEN45 Gel Stent Combined with Healaflow Injectable Viscoelastic Implant. XEN45凝胶支架联合Healaflow可注射粘弹性种植体。

IF 0.7

Case Reports in Ophthalmological Medicine Pub Date : 2023-11-22 eCollection Date: 2023-01-01 DOI: 10.1155/2023/7096406

Eloy Villarreal, Eran Berkowitz, Beatrice Tiosano

{"title":"XEN45 Gel Stent Combined with Healaflow Injectable Viscoelastic Implant.","authors":"Eloy Villarreal, Eran Berkowitz, Beatrice Tiosano","doi":"10.1155/2023/7096406","DOIUrl":"10.1155/2023/7096406","url":null,"abstract":"Purpose: To introduce a potential solution for failed glaucoma surgeries by proposing an optional surgical procedure in conjunction with the use of Healaflow (Anteis S.A., Geneva, Switzerland) as a spacer, which may potentially reduce the failure rate. Case Presentation. We present the outcomes of a surgical procedure involving the inferonasal implantation of an ab interno XEN gel stent (Allergan, Dublin, Ireland) in a 74-year-old male patient who was experiencing uncontrolled advanced glaucoma in his left eye. It is important to note that the patient had previously undergone several glaucoma surgeries and procedures in the same eye. During this particular procedure, we utilized Healaflow as a spacer by implanting the stent within a subconjunctival Healaflow \"bubble.\" At 6 months postoperatively, intraocular pressure remained on target. There was no need for additional topical medications, and no change in visual acuity was observed.Conclusion: For patients with a history of unsuccessful glaucoma surgeries and who are unsuitable candidates for tube shunt procedures or transscleral diode cyclophotocoagulation, an alternative option involves implanting the XEN45 stent in the inferior nasal region in conjunction with the use of subconjunctival Healaflow. This combined approach may provide a potential solution for managing glaucoma in these patients.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"7096406"},"PeriodicalIF":0.7,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alström's Syndrome, Leber's Hereditary Optic Neuropathy, or Retinitis Pigmentosa? A Case of Misdiagnosis. Alström综合征，Leber遗传性视神经病变，还是色素性视网膜炎?误诊一例。

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2023-11-16 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9409036

Palaiologos Alexopoulos, Chrysanthos Symeonidis, Tryfon Rotsos

{"title":"Alström's Syndrome, Leber's Hereditary Optic Neuropathy, or Retinitis Pigmentosa? A Case of Misdiagnosis.","authors":"Palaiologos Alexopoulos, Chrysanthos Symeonidis, Tryfon Rotsos","doi":"10.1155/2023/9409036","DOIUrl":"https://doi.org/10.1155/2023/9409036","url":null,"abstract":"A case of a patient with the Alström syndrome (AS) that was misdiagnosed as Leber's hereditary optic neuropathy or retinitis pigmentosa for 13 years is presented. AS is a rare genetic disorder caused by mutations in the ALMS1 gene. AS may lead to abnormal ciliary formation and function. AS affects metabolism, and symptomatology includes type 2 diabetes mellitus (T2DM), obesity, hypogonadism and gynecomastia in males, progressive bilateral sensorineural hearing loss, cardiomyopathy, nonalcoholic fatty liver disease (NAFLD), cirrhosis, and chronic progressive kidney disease. The onset of the above symptoms may vary significantly. The ophthalmic manifestation is early onset cone-rod dystrophy that starts as progressive vision loss, photophobia, and nystagmus in the first months of life. An accurate diagnosis may enable specialists to facilitate a significantly positive effect in the everyday life of a patient. Genetic counseling may also be recommended for these patients. Diagnosis was confirmed by DNA testing, thus highlighting its necessity in everyday practice.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"9409036"},"PeriodicalIF":0.9,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative Outcome of Combined Phacovitrectomy in Eyes with Excessive Myopia (>-30 D) 高度近视眼联合晶状体切除术后疗效分析(>- 30d)

Case Reports in Ophthalmological Medicine Pub Date : 2023-11-14 DOI: 10.1155/2023/7367922

Hua Fan, Mingming Zhang, Radouil Tzekov, Zhuyun Qian, Jiasong Yang, XiaoLin Xie, Wensheng Li

{"title":"Postoperative Outcome of Combined Phacovitrectomy in Eyes with Excessive Myopia (>-30 D)","authors":"Hua Fan, Mingming Zhang, Radouil Tzekov, Zhuyun Qian, Jiasong Yang, XiaoLin Xie, Wensheng Li","doi":"10.1155/2023/7367922","DOIUrl":"https://doi.org/10.1155/2023/7367922","url":null,"abstract":"Background. To report the outcomes of phacoemulsification combined with vitrectomy in eyes with extreme myopia (-30 diopters or more). Case Presentation. Three patients with cataract, vitreous opacities, and extreme myopia of more than -30 diopters underwent a combined surgical procedure of cataract extraction combined with vitrectomy. Postoperative refractive correction of the three cases ranged from -1.0 D to -2.5 D spherical equivalent. There was an obvious hyperopic shift of all cases. All patients noted a significant improvement in uncorrected and best-corrected visual acuity from 0.4 to 0.8 in case 1, from CF/70 cm to 1.0 in case 2, and from 0.12 to 0.5 in the right eye and 0.15 to 0.2 in the left eye in case 3. Vitreous floaters disappeared in all cases. No complications were noted during follow-up. Conclusions. To the best of the authors’ knowledge, these represent the first reported clinical cases of combined cataract extraction+vitrectomy surgery in eyes with extreme (>-30 D) myopia. Our results support the notion that phacoemulsification combined with vitrectomy may be a good therapeutic option for cataracts and vitreous floaters in cases with extreme myopia.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"102 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134957755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epikeratophakia for Keratoconus: A Case Report with 30 Years of Follow-Up 圆锥角膜表面角膜脱落1例，随访30年

Case Reports in Ophthalmological Medicine Pub Date : 2023-11-08 DOI: 10.1155/2023/9919057

Takashi Miyai, Tetsuya Toyono, Hitoha Ishii, Kohdai Kitamoto, Yukako Taketani, Takashi Ono, Makoto Aihara, Kazunori Miyata

{"title":"Epikeratophakia for Keratoconus: A Case Report with 30 Years of Follow-Up","authors":"Takashi Miyai, Tetsuya Toyono, Hitoha Ishii, Kohdai Kitamoto, Yukako Taketani, Takashi Ono, Makoto Aihara, Kazunori Miyata","doi":"10.1155/2023/9919057","DOIUrl":"https://doi.org/10.1155/2023/9919057","url":null,"abstract":"Background. Epikeratophakia is a refractive surgical procedure used to correct aphakic eyes, hyperopia, and keratoconus and is often performed in children. In this report, we present the long-term effects of epikeratophakia on the progression of keratoconus in a patient who underwent surgery. Case Presentation. The patient was a 17-year-old boy with keratoconus who had difficulty wearing hard contact lenses. As a solution, he underwent right eye epikeratophakia with a plano-powered lenticule. We followed up the patient for 30 years. Although the progression of keratoconus ceased in the operated eye, it continued in the nonoperated left eye and resulted in acute hydrops 9 years and 10 months after surgery. Subsequently, 20 years after the operation, anterior-segment optical coherence tomography was performed, which revealed that the progression of keratoconus had been interrupted in the right eye but had continued in the left eye, as evidenced by the parameters of the average and maximum keratometry and thinnest corneal thickness. Conclusions. Herein, we reported the longest follow-up to date of a case of keratoconus, in which one eye was treated with epikeratophakia. The progression of keratoconus was halted in the treated eye but continued in the nonoperated contralateral eye.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"25 16","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135391566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central Retinal Vein Occlusion with Three-Retinal Quadrant Involvement: Another Focus on Optic Disc Head Vascular Anatomy Variations. 视网膜中央静脉闭塞伴视网膜三象限受累：视盘头部血管解剖变异的另一个焦点。

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2023-10-31 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6648367

Narges Hassanpoor, Vahid Abdolrahimi, Mohamad Reza Niyousha

引用次数: 0

Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure. 新血管性青光眼近全联合角闭合的周期性光凝治疗。

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2023-10-26 eCollection Date: 2023-01-01 DOI: 10.1155/2023/5719002

Jessie Wang, Lindsay Y Chun, Mary Qiu

{"title":"Cyclophotocoagulation in Neovascular Glaucoma with Near-Total Synechial Angle Closure.","authors":"Jessie Wang, Lindsay Y Chun, Mary Qiu","doi":"10.1155/2023/5719002","DOIUrl":"https://doi.org/10.1155/2023/5719002","url":null,"abstract":"Objective: To describe a single surgeon's experience utilizing prompt primary slow-burn transscleral cyclophotocoagulation (CPC) with prior or concurrent anti-VEGF and subsequent aqueous shunt as needed in NVG eyes with near-total synechial angle closure at presentation.Methods: Retrospective chart review of all NVG patients with uncontrolled IOP, active anterior segment NV, near-total synechial angle closure, and no contraindications to prompt anti-VEGF who received CPC within 3 days of presentation with at least 6 months of follow-up.Results: Eight patients with mean age 60.6 years were included. Underlying etiologies were CRVO (N = 3), PDR (N = 2), CRAO (N = 1), BRVO (N = 1), and chronic RD (N = 1). All eyes underwent CPC with intravitreal anti-VEGF within 3 days of presentation. Five patients did not require subsequent aqueous shunts through a mean follow-up of 15 months; most recent visual acuities ranged from 20/40 to LP, and IOPs ranged from 5 to 11 mmHg on 0 to 3 IOP-lowering medications. Three patients who required subsequent tubes had complete regression of active anterior segment NV at the time of surgery. Most recent visual acuities ranged from 20/100 to 20/125, and IOPs ranged from 8 to 14 mmHg on 0 meds at a mean follow-up of 10 months. No eyes developed uncontrolled inflammation, sympathetic ophthalmia, or phthisis.Conclusion: Prompt primary slow-burn CPC with prior or concurrent anti-VEGF may be an effective strategy to immediately lower IOP in acute NVG eyes with active anterior segment NV and near-total synechial angle closure. If IOP becomes uncontrolled later, an aqueous shunt can be implanted in a controlled setting after active anterior segment NV has regressed.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"5719002"},"PeriodicalIF":0.9,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10622186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71478416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinal Pigment Epithelial Tears after Ex-PRESS Filtration Surgery in a Glaucoma Patient with a History of Ischemic Optic Neuropathy. 一例有缺血性视神经病变病史的青光眼患者在体外压力过滤术后视网膜色素上皮撕裂。

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2023-10-25 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6645156

Mamiko Takemoto, Yuta Kitamura, Masato Kakisu, Daisuke Shimizu, Takayuki Baba

{"title":"Retinal Pigment Epithelial Tears after Ex-PRESS Filtration Surgery in a Glaucoma Patient with a History of Ischemic Optic Neuropathy.","authors":"Mamiko Takemoto, Yuta Kitamura, Masato Kakisu, Daisuke Shimizu, Takayuki Baba","doi":"10.1155/2023/6645156","DOIUrl":"10.1155/2023/6645156","url":null,"abstract":"Background: To describe a case of retinal pigment epithelial tears (RPE tears) and serous retinal detachment (SRD) after Ex-PRESS filtration surgery for primary open-angle glaucoma (POAG) combined with ischemic optic neuropathy. Case Presentation. This case report involved a 69-year-old woman who underwent Ex-PRESS filtration surgery for right POAG. She had a history of systemic arteriosclerotic disease and subacute progressive visual field loss due to suspected ischemic optic neuropathy in her right eye. The right preoperative visual acuity was 0.7, and intraocular pressure (IOP) was 19 mmHg with maximum glaucoma eye drops. RPE detachment was not observed in the fundus. On day 9 after surgery, the IOP was 6 mmHg, and mild choroidal detachment was observed. On day 13, although IOP remained almost unchanged at 7 mmHg, bullous SRD was observed in the inferior retina, including the macula, and RPE tears were observed along the superior arcade vessel. While subretinal fluid gradually decreased with increasing IOP, tractional retinal folds persisted along the superior arcade, accompanied by macular degeneration.Conclusion: We experienced a case of RPE tears after Ex-PRESS filtration surgery. In addition to choroidal detachment in the setting of hypotony, a pathologic condition causing structural fragility of the RPE layer may contribute to the development of RPE tears.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"6645156"},"PeriodicalIF":0.9,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71421010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Five-Year Follow-Up of Repeated Intravitreal Bevacizumab for Macular Edema in a Pediatric Patient with Retinal Arteriovenous Malformation and Excellent Vision. 一例视网膜动静脉畸形且视力良好的儿童患者玻璃体内重复注射贝伐单抗治疗黄斑水肿的五年随访。

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2023-10-25 eCollection Date: 2023-01-01 DOI: 10.1155/2023/5693657

Andrew R Miller, Ivan J Lee, Zachary C Wright, Monique Leys

引用次数: 0