Case Reports in Ophthalmological Medicine最新文献

{"title":"Rhegmatogenous Retinal Detachment Associated With a Retinal Tear Overlying a Choroidal Nevus.","authors":"Georgios Mylonas, Gregor S Reiter, Markus Ritter, Gabor G Deak, Adrian Reumueller, Andreas Pollreisz, Stefan Sacu, Michael Georgopoulos","doi":"10.1155/crop/6311293","DOIUrl":"https://doi.org/10.1155/crop/6311293","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study is to report a case of a rhegmatogenous retinal detachment (RRD) associated with a retinal tear overlying a choroidal nevus.</p><p><strong>Methods: </strong>This study is a case report.</p><p><strong>Results: </strong>A 66-year-old female patient has been referred to our department because of a retinal detachment in her left eye. Her ocular history was notable for a choroidal nevus in her left eye, which has been under observation for the past 11 years without any signs of malignancy or abnormal changes. Dilated funduscopic examination revealed a superior macula-off bullous RRD that originated from a retinal tear located at the previously observed choroidal nevus. The patient successfully underwent a 23-g vitrectomy and cryotherapy with SF6 gas tamponade, combined with cataract surgery and biopsy.</p><p><strong>Conclusion: </strong>While choroidal nevi are relatively prevalent, the specific progression to RRD due to a tear is a rare occurrence in clinical practice, and it presents with unique diagnostic and therapeutic challenges.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"6311293"},"PeriodicalIF":0.4,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13142088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phakomatosis Pigmentovascularis (Type IIb) With Bilateral Glaucoma and Urrets-Zavalia Syndrome Following MicroPulse TSCPC: A Case Report.","authors":"Ali Alshehri, Yasser Bin Thabet, Mohammed Naji Almutairi","doi":"10.1155/crop/3631637","DOIUrl":"https://doi.org/10.1155/crop/3631637","url":null,"abstract":"<p><strong>Purpose: </strong>We are aimed at describing the clinical course and management of a rare case of phakomatosis pigmentovascularis (PPV Type IIb) presenting with bilateral glaucoma, complicated by bilateral Urrets-Zavalia syndrome (UZS) following MicroPulse transscleral cyclophotocoagulation (MP-TSCPC).</p><p><strong>Observations: </strong>A 6-year-old girl with PPV Type IIb and syndromic glaucoma underwent MP-TSCPC as an initial surgical intervention for uncontrolled intraocular pressure (IOP). Postoperatively, the patient developed bilateral fixed dilated pupils consistent with UZS. Due to persistent IOP elevation and the complication of UZS, bilateral deep sclerectomy (DS) was performed, resulting in adequate IOP control. (10-mmHg OD, 17-mmHg OS) and gradual improvement in pupillary function. No further complications were observed. The case was classified under PPV Type II based on the coexistence of vascular and pigmentary anomalies. A review of the literature confirms the rarity of such a constellation of findings and the sparsity of reported bilateral UZS following MP-TSCPC.</p><p><strong>Conclusion and importance: </strong>This case highlights that PPV Type IIb requires careful examination because of the risk of associated glaucoma. UZS should be considered as a possible complication after MP-TSCPC, especially when both eyes are treated. In complex cases with vascular involvement, DS can provide effective and safe IOP control.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"3631637"},"PeriodicalIF":0.4,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gonioscopy-Assisted Transluminal Trabeculotomy in Angle Recession Glaucoma: A Case Report.","authors":"Abdullah Bin Hemid, Basel M Alsolami","doi":"10.1155/crop/4075105","DOIUrl":"https://doi.org/10.1155/crop/4075105","url":null,"abstract":"<p><strong>Introduction: </strong>We report a case of angle recession glaucoma (ARG) in a 15-year-old male following blunt ocular trauma, managed with gonioscopy-assisted transluminal trabeculotomy (GATT).</p><p><strong>Case presentation: </strong>Despite maximal medical therapy, intraocular pressure (IOP) remained uncontrolled. Gonioscopy revealed approximately 5 clock hours of superior angle recession. The patient underwent GATT, which resulted in an immediate postoperative reduction in IOP, complicated by transient hyphema. At 1 year follow-up, the patient achieved stable IOP (12 mmHg) without anti-glaucoma medications, full visual recovery (20/20), and complete resolution of hyphema.</p><p><strong>Conclusion: </strong>This case highlights the potential role of GATT as an effective, minimally invasive surgical option for managing ARG.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"4075105"},"PeriodicalIF":0.4,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13128977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fungal Keratitis Following Application of Dehydrated Amniotic Membrane (Omnigen) With (OmniLenz) Bandage Contact Lens.","authors":"Bayan Ali Alsaif, Albaraa T Alfaraidi, Rawan Alshabeeb","doi":"10.1155/crop/3157153","DOIUrl":"https://doi.org/10.1155/crop/3157153","url":null,"abstract":"<p><strong>Background: </strong>Amniotic membrane is a common treatment option for several corneal and conjunctival conditions. There are several methods for preserving amniotic membrane, and each involves some compromise of the tissue integrity. Dehydrated amniotic membrane has been used for several indications, including microbial infections, aniridia, chemical burns, and limbal stem cell deficiency, as in Steven-Johnson syndrome. We report a case of fungal keratitis following the application of a sutureless dehydrated amniotic membrane using specialized bandage contact lens, OmnioLenz (NuVision Biotherapies Ltd., United Kingdom).</p><p><strong>Case report: </strong>A 34-year-old male with keratoconus who had undergone deep anterior lamellar keratoplasty presented with a recurrent epithelial defect at the graft-host junction that was not responding to conservative management. A sutureless dehydrated amniotic membrane was applied but the patient developed fungal keratitis in the central cornea. The infiltrate culture revealed <i>Candida parapsilosis</i>. The patient was started on antifungal and antibacterial topical eyedrops and showed favorable response to topical antimicrobial agents on follow-up.</p><p><strong>Conclusion: </strong>High suspicion and close observation are recommended for patients who underwent keratoplasty, especially in the presence of multiple risk factors such as dehydrated amniotic membrane transplant, to detect any signs of infection in a timely manner and thereby prevent vision-threatening complications.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"3157153"},"PeriodicalIF":0.4,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13122557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gyrate Atrophy of the Choroid and Retina Diagnosed in Adulthood With a Homozygous <i>OAT</i> Variant: A Case Report Highlighting the Need for Long-Term Care.","authors":"Hitomi Taniai, Kei Mizobuchi, Takaaki Hara, Takaaki Hayashi, Tadashi Nakano","doi":"10.1155/crop/8380205","DOIUrl":"https://doi.org/10.1155/crop/8380205","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to report a case of gyrate atrophy of the choroid and retina (GA) in a patient with a homozygous <i>OAT</i> variant who was unable to continue treatment due to loss to follow-up.</p><p><strong>Case presentation: </strong>A 21-year-old female patient (JU1902) from South Asia was referred to The Jikei University Hospital for clinical and genetic evaluation. She underwent comprehensive ophthalmic examinations and whole-exome sequencing. Genetic analysis identified a homozygous variant in the <i>OAT</i> gene: a c.272G > A (p.Gly91Glu). Fundus photography showed sharply demarcated circular areas of chorioretinal atrophy in the peripheral retina. Fundus autofluorescence imaging revealed hypoautofluorescence corresponding to these atrophic areas. Optical coherence tomography showed multiple intraretinal cystic spaces with preservation of the outer retinal layers, including the ellipsoid zone. Goldmann perimetry revealed a markedly constricted visual field, with the I-2 isopter restricted to less than 5° and the I-4 isopter within 10°-20°. Full-field electroretinography demonstrated norecordable responses under all stimulus conditions. Biochemical testing indicated markedly elevated serum and urinary ornithine concentrations. Following the genetic and clinical diagnosis, vitamin B6 supplementation was initiated at 100 mg/day. However, serum ornithine levels remained markedly elevated. Although an increased dosage of vitamin B6 (200 mg/day) and an arginine-restricted diet were considered, the patient voluntarily discontinued follow-up visits and was subsequently lost to follow-up.</p><p><strong>Conclusion: </strong>This case highlights the importance of continued treatment and follow-up in adult patients with GA. Forming a patient-centered multidisciplinary team, including professional interpreters and cultural liaisons, is essential for ensuring patient understanding, treatment adherence, and long-term visual preservation.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"8380205"},"PeriodicalIF":0.4,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13125854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ophthalmomyiasis Externa in an Atypical Region.","authors":"Alyssa Snyder, Melissa Warne, Kyle Deistler, James Law, Carisa Bohnak, Edward Wladis","doi":"10.1155/crop/4330667","DOIUrl":"https://doi.org/10.1155/crop/4330667","url":null,"abstract":"<p><p>Ophthalmomyiasis is a rare condition caused by the infestation of ocular or periocular tissues by fly larvae. It is typically reported in tropical regions, rural settings, or among individuals with animal exposure. This report presents a unique case of ophthalmomyiasis externa in a 2-year-old girl from upstate New York. The patient presented with persistent left lower eyelid edema, erythema, and discharge following an insect bite that was unresponsive to antibiotic therapy. A botfly larva was expressed with digital pressure. The case underscores the diagnostic challenges of ophthalmomyiasis in unlikely regions and raises important questions about the ecological and environmental shifts facilitating the spread of parasitic diseases. Early recognition and intervention, including larval extraction and systemic therapy, proved effective. This report highlights the need for vigilance and broader differential diagnoses in regions where such infestations are uncommon.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"4330667"},"PeriodicalIF":0.4,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitreous Hemorrhage Induced by a Persistent Hyaloid Artery.","authors":"Henry Zou, Kimberly Drenser, Brooke Geddie","doi":"10.1155/crop/6485755","DOIUrl":"https://doi.org/10.1155/crop/6485755","url":null,"abstract":"<p><strong>Background: </strong>The hyaloid artery is a branch of the ophthalmic artery and part of the fetal hyaloid vascular system; failure of these fetal vessels to regress can lead to a persistent hyaloid artery (PHA). PHA can induce complications, including amblyopia, cataracts, glaucoma, vitreous hemorrhage, and retinal detachment. We present a case of vitreous hemorrhage secondary to traction of the PHA in an infant treated for threshold retinopathy of prematurity (ROP).</p><p><strong>Case presentation: </strong>A 660-g female infant was born at 23 weeks of gestation and was found to have bilateral Stage 3 Zone 2 ROP with plus disease, prompting laser photocoagulation to the avascular retina. Six weeks after this treatment, the patient was found to have a vitreous hemorrhage requiring vitrectomy. The etiology of the hemorrhage was thought to be secondary to traction on the PHA after laser photocoagulation treatment. She developed subsequent anisometropic myopia and amblyopia, for which she continues care.</p><p><strong>Conclusions: </strong>Vitreous hemorrhage is a rare but severe complication of PHA. This unique case of traction on the PHA with subsequent vitreous hemorrhage after routine treatment of ROP highlights the importance of considering PHA in the management of ROP.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"6485755"},"PeriodicalIF":0.4,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13109780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Color-Contrast Adjustment With a 3D Head-Up System to Aid Capsulorhexis After ICG Staining: Single-Patient Case Report From a Tertiary Center.","authors":"Yukihisa Takada, Takayoshi Sumioka, Nobuyuki Ishikawa, Shizuya Saika","doi":"10.1155/crop/5414207","DOIUrl":"https://doi.org/10.1155/crop/5414207","url":null,"abstract":"<p><p>We report a single case in which continuous curvilinear capsulorhexis (CCC) was safely completed using NGENUITY in 3D head-up surgery (HUS) during cataract surgery. Visibility of the dye-stained anterior capsule was improved during the CCC procedure. An 84-year-old female underwent a planned extracapsular extraction on December 2022, in HUS using NGENUITY for a Grade 4 cataract classified by the Emery-Little classification. After staining the anterior capsule with 0.5% indocyanine green (ICG) for 5 s, the anterior chamber was washed to reduce the risk of endothelial damage. Then, CCC was performed by adding red enhancement to a monochrome-filtered image using the color contrast adjustment function of NGENUITY. The contrast of the anterior capsulotomy margin appeared sharper than in the normal setting, which enhanced the visibility of the capsulotomy margin of the anterior lens capsule. This allowed CCC to be completed smoothly and safely. Subsequently, the surgery was performed as usual and the intraocular lens (IOL) was fixed in the capsular bag to complete the procedure. One month after surgery, the fixation and position of the IOL were stable. Color channel adjustment in a 3D head-up system improved the visibility of CCC margins after ICG staining in advanced nuclear cataracts. This technique may be useful in cases with a poor red reflex. Future prospective studies using objective contrast evaluation are needed.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"5414207"},"PeriodicalIF":0.4,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sub-Tenon Emphysema From Compressed Air Injury in a Patient With Marfan Syndrome.","authors":"Adam Beyer Wolf, Achmed Pircher","doi":"10.1155/crop/8844247","DOIUrl":"https://doi.org/10.1155/crop/8844247","url":null,"abstract":"<p><p>Compressed air injuries to the globe are rare and typically associated with orbital fractures or a visible entry wound. The authors report the case of a 16-year-old male with Marfan syndrome who developed orbital emphysema strictly confined to the sub-Tenon's space following a compressed air injury, without any visible entry wound or orbital fracture. Clinical examination demonstrated a well-demarcated subconjunctival air pocket located approximately 3-4 mm posterior to the limbus, consistent with the anterior insertion of Tenon's capsule. Computed tomography confirmed a localized intraorbital air without evidence of fracture or sinus communication. A plausible mechanism is that high-pressure air entered through microscopic tissue disruption and dissected along Tenon's capsule into the sub-Tenon space. The patient was managed conservatively with spontaneous resolution. This case provides a well-documented example of localized sub-Tenon emphysema and illustrates the anatomical boundaries of the sub-Tenon space in vivo.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"8844247"},"PeriodicalIF":0.4,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipemic Aqueous Humor in Hyperlipidemia and Diabetes Mellitus: A Case Report.","authors":"Jing Wu, Jia Ying, Yu Zhu, Jun Li","doi":"10.1155/crop/9931034","DOIUrl":"https://doi.org/10.1155/crop/9931034","url":null,"abstract":"<p><strong>Introduction/background: </strong>Lipemic aqueous humor is a rare ocular condition characterized by a milky appearance in the anterior chamber, primarily associated with hyperlipidemia and poorly controlled diabetes. This case highlights the diagnostic challenges and management of lipemic aqueous humor, emphasizing the need for differentiation from other etiologies such as infectious endophthalmitis.</p><p><strong>Case presentation: </strong>A 26-year-old woman with type 1 diabetes and hyperlipidemia presented with unilateral vision loss and ocular redness. Examination revealed visual acuity of 20/400, conjunctival congestion, corneal clouding, and milky anterior chamber exudate. Laboratory tests showed severe hyperglycemia (fasting glucose 33.79 mmol/L) and hypertriglyceridemia (23.71 mmol/L). Initial management included anterior chamber irrigation and intravitreal antibiotics due to suspected infection. Treatment was augmented with corticosteroids, mydriatics, and systemic control of glucose and lipids. Visual acuity improved to 20/70 by Day 3 and recovered to 20/20 by Day 6, with stability at 1-month follow-up.</p><p><strong>Discussion/conclusion: </strong>This case underscores that lipemic aqueous humor, though rare, should be considered in the differential diagnosis of anterior chamber opacities in patients with metabolic disorders. The disruption of the blood-aqueous barrier, potentially exacerbated by underlying inflammation in the context of hyperlipidemia and diabetes, is key to its pathogenesis. Prompt diagnosis, metabolic control, and targeted anti-inflammatory therapy can lead to excellent visual outcomes, potentially avoiding unnecessary invasive interventions.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"9931034"},"PeriodicalIF":0.4,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}