Case Reports in Ophthalmological Medicine最新文献

Rare Mimic of Conjunctivitis: Conjunctival Intraepithelial Sebaceous Carcinoma. 罕见的模拟结膜炎：结膜上皮内皮脂腺癌。

IF 0.4

Case Reports in Ophthalmological Medicine Pub Date : 2025-09-19 eCollection Date: 2025-01-01 DOI: 10.1155/crop/5565300

Maedot A Haymete, Kristen Delans, Paul Varghese, Nicholas Ramey, Douglas J Grider

{"title":"Rare Mimic of Conjunctivitis: Conjunctival Intraepithelial Sebaceous Carcinoma.","authors":"Maedot A Haymete, Kristen Delans, Paul Varghese, Nicholas Ramey, Douglas J Grider","doi":"10.1155/crop/5565300","DOIUrl":"10.1155/crop/5565300","url":null,"abstract":"Sebaceous carcinoma, an uncommon malignant neoplasm, often arises de novo from periocular sebaceous glands. Commonly manifesting as diffuse eyelid thickening, sebaceous carcinoma can mimic other inflammatory processes such as persistent chalazion or blepharitis. Delayed diagnosis often complicates the disease course due to its indolent presentation. Described is a rare case of sebaceous carcinoma entirely confined to the conjunctival epithelium of the upper eyelid. An 80-year-old female presented for evaluation of bothersome \"cysts\" under her left upper lid as well as blurry vision in her left eye. The patient was repeatedly re-evaluated over the next few months and found to have Meibomian gland dysfunction of the upper and lower left eyelids as well as 3+ diffuse spongy papillary injection of the tarsal conjunctiva in the left upper lid, with large papillae and conjunctival thickening in the left inferior fornix. A conjunctival biopsy was eventually performed when appropriate management of presumed conjunctivitis failed to alleviate the patient's symptoms. Pathological examination of the left upper eyelid tarsal conjunctiva showed epithelium largely replaced by pagetoid spread of intraepithelial sebaceous carcinoma, with an underlying band-like lymphocytic infiltrate. The carcinoma was strongly adipophilin positive with variable EMA, PRAME, and Factor XIIIa positivity, confirming intraepithelial sebaceous carcinoma. The nuclei of the carcinoma had a smudged, salt-and-pepper appearance; however, CK20, INSM-1, and synaptophysin were negative, excluding Merkel cell carcinoma. A sebaceous carcinoma limited to conjunctival epithelium is rare. However, given its potential aggressive nature, it should be included in the differential diagnosis of \"nonhealing conjunctivitis\" or persistent unilateral irritation of the eyelid.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"5565300"},"PeriodicalIF":0.4,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12473728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Rehabilitation for Autosomal Dominant Retinitis Pigmentosa: A Case Report. 常染色体显性视网膜色素变性综合康复1例报告。

IF 0.4

Case Reports in Ophthalmological Medicine Pub Date : 2025-09-01 eCollection Date: 2025-01-01 DOI: 10.1155/crop/4856296

Joshua L Robinson

{"title":"Comprehensive Rehabilitation for Autosomal Dominant Retinitis Pigmentosa: A Case Report.","authors":"Joshua L Robinson","doi":"10.1155/crop/4856296","DOIUrl":"10.1155/crop/4856296","url":null,"abstract":"A 62-year-old female with retinitis pigmentosa presented for a low vision rehabilitation evaluation. An updated spectacle prescription, filters, and task lighting were beneficial, but the patient was left with outstanding needs. She noted that she had lost her independence and felt trapped within her own home with nobody around who could fully understand her situation. Genetic testing confirmed autosomal dominant retinitis pigmentosa and provided answers regarding prognosis and family tree considerations. White cane mobility training allowed her to be more independent when traveling. Independent living skills training equipped her to be safer and more autonomous at home. Assistive technology training empowered her to use her digital devices more efficiently to reconnect with friends, family, and the world. A visually impaired clinical counselor helped the patient to work through the process of grieving her vision loss, while involvement in peer support groups allowed her to connect with a new community and recognize future potential. The training and support resources utilized in this case combined to help an individual adapt in response to a challenging diagnosis and prognosis. Such resources should never be overlooked or underestimated in cases of irreversible vision loss.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"4856296"},"PeriodicalIF":0.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12417062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microperimetry and Multifocal Electroretinogram in a Patient With Unilateral Retinal Pigment Epithelium Dysgenesis (URPED). 单侧视网膜色素上皮发育不良（URPED）患者的显微视野和多焦视网膜电图。

IF 0.4

Case Reports in Ophthalmological Medicine Pub Date : 2025-08-14 eCollection Date: 2025-01-01 DOI: 10.1155/crop/7911612

Beatriz de Lucena Ribeiro, Ana Lucia Passos Peixoto, Ana Paula Couto, Rafael Erthal Robbs, Wander Borges, Julieta Micherif, Giovanna Provenzano, Raul N G Vianna

{"title":"Microperimetry and Multifocal Electroretinogram in a Patient With Unilateral Retinal Pigment Epithelium Dysgenesis (URPED).","authors":"Beatriz de Lucena Ribeiro, Ana Lucia Passos Peixoto, Ana Paula Couto, Rafael Erthal Robbs, Wander Borges, Julieta Micherif, Giovanna Provenzano, Raul N G Vianna","doi":"10.1155/crop/7911612","DOIUrl":"10.1155/crop/7911612","url":null,"abstract":"Introduction: This study is aimed at describing a patient with unilateral retinal pigment epithelium dysgenesis (URPED) using multimodal retinal imaging combined with ocular microperimetry and multifocal electroretinogram (ERG) analysis. Case presentation: A 56-year-old healthy male was referred for a routine ophthalmologic control. His best corrected visual acuity was 20/20 and 20/25 in the right and left eye, respectively. Fundus examination of the left eye revealed a well-circumscribed, large yellowish-white lesion on the posterior pole that extended from the peripapillary region to the inferior temporal vascular arcade, sparing the fovea. This characteristic fundus picture led us to the diagnosis of URPED. Microperimetry demonstrated a progressive decrease of sensitivity from the normal retina toward the lesion borders, reaching a value of 0 dB at its center. Multifocal ERG displayed a reduction of central amplitudes in the involved eye. Discussion: Our findings indicate a varied degree of sensitivity at the site of the lesion. Despite good visual acuity, multifocal ERG revealed reduced macular function.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"7911612"},"PeriodicalIF":0.4,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Congenital Glaucoma in a 5-Year-Old Patient With Sturge-Weber Syndrome and Oculodermal Melanocytosis. 5岁先天性青光眼伴斯特奇-韦伯综合征及眼真皮黑色素细胞增多症1例。

IF 0.4

Case Reports in Ophthalmological Medicine Pub Date : 2025-08-01 eCollection Date: 2025-01-01 DOI: 10.1155/crop/3902349

Param Shukla, Miriam Habiel

引用次数: 0

Neuro-Ophthalmic Manifestation Associated With COVID-19 in a Tertiary Eye Center in Nepal. 尼泊尔某三级眼科中心与COVID-19相关的神经眼科表现

IF 0.4

Case Reports in Ophthalmological Medicine Pub Date : 2025-07-26 eCollection Date: 2025-01-01 DOI: 10.1155/crop/6694537

Sanjeeta Sitaula, Chiranjiwi Shah, Ganga Sagar Shah, Rajeev Ojha

{"title":"Neuro-Ophthalmic Manifestation Associated With COVID-19 in a Tertiary Eye Center in Nepal.","authors":"Sanjeeta Sitaula, Chiranjiwi Shah, Ganga Sagar Shah, Rajeev Ojha","doi":"10.1155/crop/6694537","DOIUrl":"10.1155/crop/6694537","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) primarily involves the respiratory system, but can manifest with a variety of neuro-ophthalmic symptoms. Here, we describe three cases presenting with neuro-ophthalmic manifestations secondary to COVID-19 at a tertiary center in Nepal. The first case was a 42-year-old male with sudden onset painless loss of vision noticed in the right eye (RE) after COVID-19 infection. Examination findings in the RE showed best corrected visual acuity (BCVA) of 6/18 with relative afferent pupillary defect positive and superior sectoral disk edema in the same eye. The case was diagnosed as RE nonarteritic ischemic optic neuropathy associated with COVID-19 infection. Our second case was a 41-year-old female who developed bilateral sudden diminution of vision associated with headache and vomiting on the third day of testing positive for COVID-19 infection. She had bilateral BCVA of 6/12 and sluggishly reacting pupils in both eyes. Dilated fundus examination showed established disk edema. Imaging of the brain showed dural venous sinus (transverse and sagittal) thrombosis. So, the diagnosis of papilledema secondary to COVID-19 associated cerebral venous sinus thrombosis (CVST) was established. The third case was a 40-year-old male with right sixth cranial nerve palsy, ischemic stroke involving the right occipital lobe and posterior limb of the right internal capsule along with thrombosis of the left common iliac artery in the absence of any other preexisting vascular risk factors. Severe inflammatory reaction to COVID-19 causing a hypercoagulable state may be the causal factor in neuro-ophthalmic findings in our case series.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"6694537"},"PeriodicalIF":0.4,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144774685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Central Toxic Keratopathy Induced by Exposure to Chinese Herbal Medicine Fluid for Verruca Plana: A Case Report. 接触平疣中草药液致急性中枢性中毒性角膜病变1例。

IF 0.4

Case Reports in Ophthalmological Medicine Pub Date : 2025-07-22 eCollection Date: 2025-01-01 DOI: 10.1155/crop/8657147

Shuang Zhang, Yong Tao

{"title":"Acute Central Toxic Keratopathy Induced by Exposure to Chinese Herbal Medicine Fluid for Verruca Plana: A Case Report.","authors":"Shuang Zhang, Yong Tao","doi":"10.1155/crop/8657147","DOIUrl":"10.1155/crop/8657147","url":null,"abstract":"Purpose: The purpose of this study was to report a case of acute central toxic keratopathy due to exposure to Chinese herbal medicine fluid treating verruca plana. Methods: A 46-year-old woman presented with pain and blurred vision in her right eye for 3 days. Her right eye was unintentionally exposed to a medication in liquid form treating the verruca plana on her eyelids. The drug was a compound preparation with complex Chinese herbal medicinal ingredients. Results: Slit lamp examination showed central diffuse corneal subepithelial haze with granular shapes and anterior stromal opacity. Corresponding with her clinical manifestations, anterior segment optical coherence tomography revealed diffuse abnormal highly reflective signal in the anterior stroma within 349 μm and in vivo confocal microscopy found inflammatory infiltration in the subepithelial and the anterior stromal layer. Thus, tobramycin dexamethasone eye drops and artificial tears were prescribed for her, which proved effective. Her clinical symptoms and signs were both resolved after steroid treatment and remained stable at the 1-month follow-up. Conclusion: Acute central toxic keratopathy could occur after exposure to Chinese herbal medicine fluid, and enhanced topical steroid treatment worked well for alleviating inflammation and reducing corneal opacity.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"8657147"},"PeriodicalIF":0.4,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12308051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chondroblastoma-Like Chondroma of Soft Tissue Arising at the Outer Canthus: A Case Report. 发生于外眼角的软组织成软骨细胞瘤样软骨瘤1例。

IF 0.7

Case Reports in Ophthalmological Medicine Pub Date : 2025-07-16 eCollection Date: 2025-01-01 DOI: 10.1155/crop/2036386

Dejan M Rašić, Dolika D Vasović, Jelena Sopta

引用次数: 0

Central Retinal Vein Occlusion Associated With Progestin-Only Contraceptive Implant Use. 仅使用孕激素避孕植入物与视网膜中央静脉阻塞相关。

IF 0.7

Case Reports in Ophthalmological Medicine Pub Date : 2025-07-14 eCollection Date: 2025-01-01 DOI: 10.1155/crop/5558602

Jan Patrick O Chu, David I T Sia

{"title":"Central Retinal Vein Occlusion Associated With Progestin-Only Contraceptive Implant Use.","authors":"Jan Patrick O Chu, David I T Sia","doi":"10.1155/crop/5558602","DOIUrl":"10.1155/crop/5558602","url":null,"abstract":"Purpose: The purpose of the study is to present a case of central retinal vein occlusion (CRVO) associated with the use of progestin-only contraceptive implant. Methods: The study is a case report. Results: This is a case of a 34-year-old Caucasian female nonsmoker who presented with sudden-onset painless blurring of vision of the left eye. There were no associated ocular and systemic signs or symptoms. She has no comorbidities. The patient disclosed that she was on the etonogestrel implant, a progestin-only contraceptive, at the time of consult. She was previously diagnosed with a CRVO of the right eye while on the combined hormonal contraceptive in 2017. She had a best corrected visual acuity (BCVA) of 6/6 in both eyes. Anterior segment examinations of both eyes were unremarkable. Fundus examination of the right eye revealed normal findings; however, the fundus exam of the left eye showed a clear media with a healthy looking disc but with sparse dot blot hemorrhages in all retinal quadrants and dilated and tortuous retinal vessels, along with a healthy-looking macula. Macular optical coherence tomography (OCT) did not show any signs of macular edema. Carotid ultrasound, autoimmune, and coagulation panels were all normal. Subsequent visits showed complete resolution of the retinal hemorrhages, and the retinal vasculature returned to normal anatomical configuration. A diagnosis of left CRVO secondary to etonogestrel implant was made. Conclusion: This study recognized that the use of progestin-only contraceptives still has an increased risk of thrombosis. It is essential to consider the mode of administration and duration of use of these contraceptives.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"5558602"},"PeriodicalIF":0.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144682096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent Hypotony Following Antiglaucoma Surgery: A Case Report. 抗青光眼手术后持续低眼压1例报告。

IF 0.7

Case Reports in Ophthalmological Medicine Pub Date : 2025-07-11 eCollection Date: 2025-01-01 DOI: 10.1155/crop/8839203

Shuxin Cai, Haibo Li, Shuimiao Chen, Ranqing Lin

引用次数: 0

Primary Orbital Teratoma With Congenital Anophthalmia in a Neonate: A Rare Case With Histopathological and Radiological Correlation. 新生儿原发性眼眶畸胎瘤合并先天性眼无：一例少见的组织病理学和放射学相关性。

IF 0.7

Case Reports in Ophthalmological Medicine Pub Date : 2025-06-27 eCollection Date: 2025-01-01 DOI: 10.1155/crop/5032089

Dejan M Rašić, Dolika D Vasović, Miroslav Knežević

引用次数: 0