Case Reports in Ophthalmological Medicine最新文献

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Vitreopapillary Traction Causing Optic Nerve Head Elevation. 玻璃体乳头牵引引起视神经头抬高。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.1155/crop/3136288
Mohamed M Khodeiry, Mohammad Ayoubi, Christopher A Dorizas, Carlos E Mendoza-Santiesteban, Maja Kostic
{"title":"Vitreopapillary Traction Causing Optic Nerve Head Elevation.","authors":"Mohamed M Khodeiry, Mohammad Ayoubi, Christopher A Dorizas, Carlos E Mendoza-Santiesteban, Maja Kostic","doi":"10.1155/crop/3136288","DOIUrl":"https://doi.org/10.1155/crop/3136288","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of the study is to describe a case of vitreopapillary traction causing optic nerve head elevation. <b>Observations:</b> This case report describes a 64-year-old male who presented with left cloudy vision for 3 days. Dilated fundus exam showed normal right optic nerve with glial tissue nasally and left optic nerve head elevation and peripapillary hemorrhages in the left eye. Magnetic resonance imaging of the brain and orbits, erythrocyte sedimentation rate, and C-reactive protein were normal. Optical coherence tomography showed bilateral dense vitreous adhesions to the optic disc nasally causing traction and optic nerve head elevation of the left eye. The patient was diagnosed with vitreopapillary traction causing optic nerve head elevation, and observation was recommended. <b>Conclusions and Importance:</b> This case highlights the importance of clinical examination and ancillary testing in differentiating etiologies of optic disc elevation.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"3136288"},"PeriodicalIF":0.7,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eyelash Impalement of Iris After Uncomplicated Cataract Surgery. 无并发症白内障手术后睫毛刺入虹膜。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.1155/crop/6657874
Jenny Y Gan, Michael M Lin
{"title":"Eyelash Impalement of Iris After Uncomplicated Cataract Surgery.","authors":"Jenny Y Gan, Michael M Lin","doi":"10.1155/crop/6657874","DOIUrl":"https://doi.org/10.1155/crop/6657874","url":null,"abstract":"<p><p>This report highlights the first known report of an intraocular eyelash embedded in the inferior midperipheral iris following a routine cataract surgery. A 74-year-old female presented 5 months postoperatively from a full-thickness macular hole repair with a 3+ nuclear sclerotic cataract. She underwent an uneventful left eye cataract extraction with insertion of posterior chamber intraocular lens (PCIOL). Review of surgical video revealed well-draped eyelashes and no introduction of an eyelash into the anterior chamber at any point during surgery. The first postoperative visit was notable for no foreign bodies and centered PCIOL. Then, 1 week postoperatively, the anterior segment examination revealed a linear foreign body embedded in the inferior midperipheral iris, without corneal endothelium touch. The foreign body was removed in the operating room and revealed to be an eyelash by pathology. The patient's visual acuity during her first two postoperative visits was 20/30 and improved to 20/20 with refraction at her 1-month postoperative visit. There was minimal postoperative inflammation and no evidence of endophthalmitis. To prevent introduction of an intraocular eyelash associated with cataract surgery, appropriate measures intraoperatively and postoperatively should be taken, including meticulous draping of the eyelashes and lids, diligent corneal wound hydration, and clear patient education.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"6657874"},"PeriodicalIF":0.7,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11991761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Goldenhar Syndrome and Surgical Reconstruction: A Case Report of Bilateral Complete Eyelid Colobomas in a 2-Day-Old Patient. Goldenhar综合征与手术重建术:2日龄双侧完全性眼睑缺损1例报告。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-03-21 eCollection Date: 2025-01-01 DOI: 10.1155/crop/6640462
Rawan S Utt, Suad M Udwan, Waed Amro, Safaa Abatli, Saja Saadeh Issa, Bashar M Y Jaber
{"title":"Goldenhar Syndrome and Surgical Reconstruction: A Case Report of Bilateral Complete Eyelid Colobomas in a 2-Day-Old Patient.","authors":"Rawan S Utt, Suad M Udwan, Waed Amro, Safaa Abatli, Saja Saadeh Issa, Bashar M Y Jaber","doi":"10.1155/crop/6640462","DOIUrl":"10.1155/crop/6640462","url":null,"abstract":"<p><p>Goldenhar syndrome (GS), also known as Franceschetti-GS, encompasses a spectrum of congenital anomalies affecting the eyes, ears, face, and vertebrae. This case report highlights a 2-day-old female patient diagnosed with GS presenting a rare manifestation of bilateral complete eyelid colobomas. The patient, with associated renal and cardiac problems, underwent surgical interventions, including bilateral lower lid frost suture tarsorrhaphy and subsequent upper lid reconstructions. Despite challenges and complications, the patient showed varying degrees of improvement in corneal conditions postsurgery. The discussion provides insights into the clinical features, diagnosis, and multidisciplinary management of GS. The presented case emphasizes the importance of tailored surgical approaches in addressing the complex ocular manifestations of GS, aiming for functional and aesthetic outcomes. Ongoing follow-up and further reconstruction surgeries are planned to optimize visual outcomes and address residual complications.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"6640462"},"PeriodicalIF":0.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Resolution of Multilayered Pigment Epithelial Detachment Lamellae Following Brolucizumab Treatment-A Case Report. 博卢珠单抗治疗后多层色素上皮脱离片状的新解决方案- 1例报告。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-03-06 eCollection Date: 2025-01-01 DOI: 10.1155/crop/9953015
Unnikrishnan Nair, Indu J Nair, Jay U Sheth, Manoj Soman
{"title":"Novel Resolution of Multilayered Pigment Epithelial Detachment Lamellae Following Brolucizumab Treatment-A Case Report.","authors":"Unnikrishnan Nair, Indu J Nair, Jay U Sheth, Manoj Soman","doi":"10.1155/crop/9953015","DOIUrl":"https://doi.org/10.1155/crop/9953015","url":null,"abstract":"<p><p><b>Purpose:</b> The aim of this study is to report a unique case where brolucizumab administration resolved multilayered pigment epithelial detachment (MLPED) lamellae. <b>Observations:</b> An 80-year-old gentleman with polypoidal choroidal vasculopathy developed MLPED from long-term ranibizumab treatment. Switching to brolucizumab led to visual acuity improvement after three doses and complete resolution of fluid, reduced choroidal thickness, and MLPED collapse. Notably, the patient experienced a recurrence of MLPED, which again resolved after the fourth dose of brolucizumab. <b>Conclusions and Importance:</b> This case underscores the effectiveness of brolucizumab in resolving MLPED lamellae, a previously unreported phenomenon. Furthermore, it highlights the potential for visual acuity improvement despite MLPED resolution. Brolucizumab's mechanism of action, including its potent antivascular endothelial growth factor properties and enhanced tissue penetration, may contribute to the collapse of MLPED by modulating subretinal pigment epithelial fluid dynamics. Further research into molecular pathways, cellular interactions, and safety profiles is warranted to optimize the therapeutic role of brolucizumab.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"9953015"},"PeriodicalIF":0.7,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11991755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unilateral Iris Transillumination Resembling BAIT Phenotype Following Contralateral Vitrectomy. 对侧玻璃体切除术后单侧虹膜透光类似诱饵表型。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-03-05 eCollection Date: 2025-01-01 DOI: 10.1155/crop/6612262
Olivier Lambrechts, Luc Van Os
{"title":"Unilateral Iris Transillumination Resembling BAIT Phenotype Following Contralateral Vitrectomy.","authors":"Olivier Lambrechts, Luc Van Os","doi":"10.1155/crop/6612262","DOIUrl":"https://doi.org/10.1155/crop/6612262","url":null,"abstract":"<p><p><b>Objective:</b> This study is aimed at describing a unilateral presentation of acute iris transillumination following contralateral vitrectomy with postoperative endophthalmitis. <b>Methods:</b> This case study is based on the medical record of a patient who presented to our hospital in 2017. <b>Results:</b> A 70-year-old female patient presented to our department with metamorphopsia and decreased vision in the right eye. She was diagnosed with a Stage 3 macular hole in the right eye for which she underwent 23G pars plana vitrectomy with gas tamponade. Postoperative topical treatment of tobramycin/dexamethasone was administered. Nine days after surgery, she presented to a different medical center with postoperative endophthalmitis in the right eye. Oral moxifloxacin was administered, an intravitreal injection with vancomycin was performed, and topical treatment with dexamethasone/chloramphenicol and neomycin/polymyxin B/dexamethasone was started. One month after surgery, she presented again to our department, this time with scleritis with associated anterior uveitis of the left eye. She was treated with oral ibuprofen, topical prednisolone acetate, and atropine sulfate, which resulted in clinical resolution. Three weeks after this episode, the left eye showed patchy transillumination of the iris matching the bilateral acute iris transillumination (BAIT) syndrome phenotype; however, the iris in the right eye remained normal. <b>Conclusion:</b> To the best of our knowledge, this case is the first to show a unilateral phenotype of BAIT after contralateral vitrectomy. This suggests that previous vitrectomy, injection of vancomycin, or topical corticosteroids or chloramphenicol could be protective against the development of acute iris transillumination.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"6612262"},"PeriodicalIF":0.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11991834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventional Retrospective Case Series of Patients Undergoing Treatment Intervals of More Than Twenty-Four (24) Weeks With Faricimab. Faricimab治疗间隔超过24周的介入回顾性病例系列。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1155/crop/8843375
Adrian Babel, Eric K Chin, David Almeida
{"title":"Interventional Retrospective Case Series of Patients Undergoing Treatment Intervals of More Than Twenty-Four (24) Weeks With Faricimab.","authors":"Adrian Babel, Eric K Chin, David Almeida","doi":"10.1155/crop/8843375","DOIUrl":"10.1155/crop/8843375","url":null,"abstract":"<p><p><b>Purpose:</b> The aim of this study is to evaluate the efficacy and safety of intravitreal faricimab dosing interval at and beyond 24 weeks in patients with diabetic macular edema (DME) and neovascular age-related macular degeneration (nAMD). <b>Methods:</b> This study is a retrospective case series of eight patients with persistent DME and nAMD who received intravitreal faricimab at and beyond the 24-week (6-month) dosing interval regimen. <b>Results:</b> The majority of patients experienced an improved mean best-corrected visual acuity (BCVA) of 9.9 letters; congruent anatomical improvement (mean central macular thickness (CMT)) decrease of 44 <i>μ</i>m on optical coherence tomography (OCT) is demonstrated at 6 months despite extended faricimab dosing intervals. <b>Conclusions:</b> Extended intravitreal faricimab dosing intervals at and beyond 24 weeks maintained visual and anatomical outcomes in patients over 1 year. This suggests the feasibility of personalized extended dosing tailored to each patient's disease activity, potentially reducing treatment burden.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"8843375"},"PeriodicalIF":0.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report and Literature Review of Conjunctival Melanoma in the Black Population. 黑人结膜黑色素瘤病例报告及文献回顾。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1155/crop/5578922
Oscar Chen, Fae Kayarian, Elaine Kelly, Richard J Grostern, Anjali Tannan
{"title":"Case Report and Literature Review of Conjunctival Melanoma in the Black Population.","authors":"Oscar Chen, Fae Kayarian, Elaine Kelly, Richard J Grostern, Anjali Tannan","doi":"10.1155/crop/5578922","DOIUrl":"10.1155/crop/5578922","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study is to report a rare case of conjunctival melanoma (CM) in a black male patient and provide a comprehensive literature review of all documented cases of CM in the black population. <b>Methods:</b> A case report highlighting a black patient with newly diagnosed CM was described. A comprehensive literature review was conducted to determine the prevalence of CM in the black population. <b>Results:</b> Extensive CM in situ in a 46-year-old black male patient was treated with excision and cryotherapy. The patient subsequently required repeat cryotherapy and topical Mitomycin C therapy due to a recurrence of pigmentation. A literature review identified 46 cases of CM in the black population. <b>Conclusions:</b> CM has rarely been observed in the black population. With this current case report, there are only 47 black patients found in the literature with this ocular surface tumor. Further detailed documentation on the presentation, location, and outcomes of CM in this population is imperative to better screen and treat this demographic.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"5578922"},"PeriodicalIF":0.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845260/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal Imaging of a Case of Monitoring of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE): Long-Term Follow-Up. 急性后部多灶性Placoid Pigment epithelial opathy (APMPPE) 1例的多模式影像监测:长期随访。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1155/crop/9924678
Monika Sarna, Michal Wilczynski, Arleta Waszczykowska
{"title":"Multimodal Imaging of a Case of Monitoring of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE): Long-Term Follow-Up.","authors":"Monika Sarna, Michal Wilczynski, Arleta Waszczykowska","doi":"10.1155/crop/9924678","DOIUrl":"10.1155/crop/9924678","url":null,"abstract":"<p><p>An 18-year-old male presented with bilateral vision loss, worsening over 10 days in the left eye and rapidly in the right eye following a suspected viral respiratory infection. On admission, his best corrected visual acuity (BCVA) was 0.9 in the right eye and 0.025 in the left. No inflammation was found in the anterior segment or vitreous body, but both eyes showed multiple yellow-white, plaque-like lesions in the retina and choroid, with foveal involvement in the left eye. Diagnostic tests revealed choriocapillaris flow deficits (optical coherence tomography angiography (OCTA)), hyperreflective changes in the outer retina and choroidal thickening (optical coherence tomography (OCT)), hypofluorescence and patchy hyperfluorescence (fluorescein angiography (FA)), hypoautofluorescence with peripheral hyperautofluorescence (fundus autofluorescence (FAF)), reduced a- and b-wave amplitudes (electroretinogram (ERG)), and scotomas with decreased retinal sensitivity (visual field (VF)). The presence of HLA-B15 and HLA-B35 antigens was confirmed. Treatment with oral methylprednisolone and intravenous acyclovir led to significant improvement within 1 day. BCVA improved to 0.9 in the right eye and 0.25 in the left, with further improvement to 0.9 and 0.5 9 days after discharge. Full visual recovery was achieved within 5 weeks. This case underscores the diagnostic value of OCTA and suggests a potential genetic predisposition linked to HLA-B15 and HLA-B35. It also highlights the effectiveness of methylprednisolone and acyclovir in APMPPE following a viral infection.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"9924678"},"PeriodicalIF":0.7,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Sarcoid Uveitis Diagnosed With Mammography Two Months After Normal Chest Imaging. 乳房x光检查诊断结节性葡萄膜炎1例。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.1155/crop/8871004
Madison Riccardi, Robert Contento, Cory Christensen, Amy Brady, Rebecca L Swan, Robert T Swan
{"title":"A Case of Sarcoid Uveitis Diagnosed With Mammography Two Months After Normal Chest Imaging.","authors":"Madison Riccardi, Robert Contento, Cory Christensen, Amy Brady, Rebecca L Swan, Robert T Swan","doi":"10.1155/crop/8871004","DOIUrl":"10.1155/crop/8871004","url":null,"abstract":"<p><p><b>Purpose:</b> Sarcoidosis is a systemic inflammatory disease associated with ocular involvement in 20%-30% of cases. The current gold standard for detecting sarcoidosis is computed tomography of the thorax, which is 73% sensitive. Definitive diagnosis necessitates biopsy, with Schaumann bodies and non-necrotizing granulomas serving as key pathological hallmarks. <b>Observations:</b> Our patient, a 44-year-old White female, presented for a second opinion on her bilateral chronic intermediate uveitis with intractable chronic cystoid macular edema of the left eye. Our clinical suspicion for sarcoidosis was high, but the computed tomography thorax scan did not show any abnormal findings. A routine mammogram completed 4 weeks prior to our initial evaluation showed axillary lymph node enlargement with calcifications. Subsequent biopsy was consistent with sarcoidosis. Treatment with mycophenolate mofetil resolved the uveitis and macular edema. <b>Conclusions and Importance:</b> The diagnosis of sarcoidosis can be challenging due to nonspecific ocular signs and the potential for falsely negative findings on imaging. This case highlights the importance of patient education and self-surveillance regarding the characteristic systemic symptoms of sarcoidosis, which commonly involve the lungs, eyes, skin, joints, etc. Our report demonstrates the significance of maintaining a high level of suspicion for sarcoidosis in patients with characteristic ocular findings, even when initial imaging results are negative or inconclusive.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"8871004"},"PeriodicalIF":0.7,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11839256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Varying Spectrum of Frosted Branch Angiitis: A Curated Constellation of Cases. 霜状支血管炎的不同频谱:一个策划的案例星座。
IF 0.7
Case Reports in Ophthalmological Medicine Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1155/crop/8844545
Avik Dey Sarkar, V Muthukrishnan, Naresh Babu Kannan, Ananya Goswami
{"title":"Varying Spectrum of Frosted Branch Angiitis: A Curated Constellation of Cases.","authors":"Avik Dey Sarkar, V Muthukrishnan, Naresh Babu Kannan, Ananya Goswami","doi":"10.1155/crop/8844545","DOIUrl":"10.1155/crop/8844545","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study is to elucidate varying etiology and presentations of frosted branch angiitis (FBA), a rare immune-mediated retinal vasculitis. <b>Methods:</b> In this case series, four curated cases confined to varying spectrums of FBA have been described. Detailed fundoscopic documentation with pertinent imaging was performed in all the cases. The cases were managed adequately as per protocol and retrospectively analyzed. <b>Results:</b> Our first case is unique as it has been rarely reported in extant ophthalmic literature. The case is presented as progressive outer retinal necrosis in cytomegalovirus (CMV) retinitis accompanied by FBA. The second case is a Kleiner Type 3 FBA with viral prodrome. Our third case is the fourth reported case in literature of FBA following penetrating trauma. This case is instrumental in confirming the hypothesis of Type 3 hypersensitivity reaction in the slow deposition of immune complexes in the periarteriolar region as a pathophysiology for FBA. The fourth case is the first reported case of coexisting bilateral flecked retina and FBA. It also had an unusual association with tuberculosis mimicking tubercular vasculitis. <b>Conclusion:</b> This gamut of unique cases may contribute to a better understanding of the variability of clinical presentation of FBA in a more detailed manner for future reference.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"8844545"},"PeriodicalIF":0.7,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832258/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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