Dejan M Rašić, Dolika D Vasović, Miroslav Knežević
{"title":"新生儿原发性眼眶畸胎瘤合并先天性眼无:一例少见的组织病理学和放射学相关性。","authors":"Dejan M Rašić, Dolika D Vasović, Miroslav Knežević","doi":"10.1155/crop/5032089","DOIUrl":null,"url":null,"abstract":"<p><p>This case report describes a rare instance of primary orbital teratoma with anophthalmia in a neonate. A 6-day-old female presented with a congenital right orbital swelling and absence of visible ocular structures. MRI revealed a large, well-vascularized orbital mass without intracranial extension, accompanied by malformations in the right cerebral hemisphere. Histopathological examination confirmed a benign, mature/mixed teratoma comprising elements from all three germ layers, including neuroectoderm, mesoderm, and endoderm, with no evidence of malignancy. The patient underwent successful orbital exenteration with an implant at 3 weeks of age.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"5032089"},"PeriodicalIF":0.7000,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253985/pdf/","citationCount":"0","resultStr":"{\"title\":\"Primary Orbital Teratoma With Congenital Anophthalmia in a Neonate: A Rare Case With Histopathological and Radiological Correlation.\",\"authors\":\"Dejan M Rašić, Dolika D Vasović, Miroslav Knežević\",\"doi\":\"10.1155/crop/5032089\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This case report describes a rare instance of primary orbital teratoma with anophthalmia in a neonate. A 6-day-old female presented with a congenital right orbital swelling and absence of visible ocular structures. MRI revealed a large, well-vascularized orbital mass without intracranial extension, accompanied by malformations in the right cerebral hemisphere. Histopathological examination confirmed a benign, mature/mixed teratoma comprising elements from all three germ layers, including neuroectoderm, mesoderm, and endoderm, with no evidence of malignancy. The patient underwent successful orbital exenteration with an implant at 3 weeks of age.</p>\",\"PeriodicalId\":9603,\"journal\":{\"name\":\"Case Reports in Ophthalmological Medicine\",\"volume\":\"2025 \",\"pages\":\"5032089\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12253985/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Ophthalmological Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1155/crop/5032089\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Ophthalmological Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crop/5032089","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Primary Orbital Teratoma With Congenital Anophthalmia in a Neonate: A Rare Case With Histopathological and Radiological Correlation.
This case report describes a rare instance of primary orbital teratoma with anophthalmia in a neonate. A 6-day-old female presented with a congenital right orbital swelling and absence of visible ocular structures. MRI revealed a large, well-vascularized orbital mass without intracranial extension, accompanied by malformations in the right cerebral hemisphere. Histopathological examination confirmed a benign, mature/mixed teratoma comprising elements from all three germ layers, including neuroectoderm, mesoderm, and endoderm, with no evidence of malignancy. The patient underwent successful orbital exenteration with an implant at 3 weeks of age.