Case Reports in Ophthalmological Medicine最新文献

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Valsalva Retinopathy Presenting as Subretinal Hemorrhage 表现为视网膜下出血的瓦尔萨尔瓦视网膜病变
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-04-05 DOI: 10.1155/2024/4865222
L. Conci, Eliza Pereira, Samia Navajas, Epitacio Silva Neto, Sérgio Pimentel, Leandro Zacharias
{"title":"Valsalva Retinopathy Presenting as Subretinal Hemorrhage","authors":"L. Conci, Eliza Pereira, Samia Navajas, Epitacio Silva Neto, Sérgio Pimentel, Leandro Zacharias","doi":"10.1155/2024/4865222","DOIUrl":"https://doi.org/10.1155/2024/4865222","url":null,"abstract":"Purpose. To describe a case of subretinal hemorrhage due to the Valsalva maneuver in a patient with no underlying chorioretinal disease. Methods. History and clinical examination, optical coherence tomography (OCT), fluorescein, and indocyanine green angiography. Results. We report a case of a 35-year-old man with a 4-day history of central vision loss in the left eye (OS) after a vomiting episode. His best-corrected visual acuity was 20/200 in OS. Fundus examination revealed a subretinal hemorrhage in the posterior pole, associated with a small preretinal hemorrhage in the superotemporal arcade. OCT confirmed the presence of a thick submacular hemorrhage and a focal hemorrhage beneath the inner limiting membrane along the superotemporal arcade. The patient was submitted to pars plana vitrectomy (PPV), subretinal injection of tissue plasminogen activator (tPA), and air tamponade on the following day. Most of the submacular hemorrhage was displaced, resulting in a satisfactory visual outcome (BCVA=20/30 after 1 month of surgery). Fluorescein and indocyanine green angiography excluded conditions such as retinal arterial macroaneurysm, polypoidal chorioretinopathy, and choroidal neovascularization. Conclusion. Although rare, Valsalva retinopathy may present with submacular hemorrhage in a patient with no underlying chorioretinal disease. PPV and subretinal tPA injection may provide a good visual outcome.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140739228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scleral Fixation of Toric Intraocular Lens in the Absence of Capsular Support 在无囊膜支撑的情况下巩膜固定散光眼内透镜
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-04-03 DOI: 10.1155/2024/7157592
Karolina Krix-Jachym, Natalia Błagun, Marek Rękas
{"title":"Scleral Fixation of Toric Intraocular Lens in the Absence of Capsular Support","authors":"Karolina Krix-Jachym, Natalia Błagun, Marek Rękas","doi":"10.1155/2024/7157592","DOIUrl":"https://doi.org/10.1155/2024/7157592","url":null,"abstract":"The study is aimed at describing a technique for scleral fixation of toric intraocular lens (TIOL) in the eyes without capsular support coexisting with corneal astigmatism. A monofocal toric hydrophobic lens with eyelets at the optic-haptic junction (enVista One-Piece Hydrophobic Acrylic MX60T Toric IOL; Bausch & Lomb) was fixated to the sclera using two fragments of 6–0 polypropylene monofilament, the ends of which were brought out through the sclera and cauterized. The astigmatic axis of a TIOL was adjusted according to the corneal astigmatic axis of the patient. The surgery was performed in the 5 eyes of 5 patients without capsular support. The method was safe and effective in fixing the lens to the sclera, and it ensured good centration of TIOL with predictable refractive outcomes. No conjunctival sutures, glue, or flap formation was required during the surgery. There were no relevant complications related to the procedure.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140750683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Focal Choroidal Excavation and Central Serous Chorioretinopathy Coexisting in a Male Patient 一名男性患者同时患有双侧局灶性脉络膜切除和中央浆液性脉络膜视网膜病变
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-03-26 DOI: 10.1155/2024/5519361
Jie Bai, Yanqing Wang, Nanjue Cao, Yan Liu, Xufei Chen, Ting He, Shan Wang
{"title":"Bilateral Focal Choroidal Excavation and Central Serous Chorioretinopathy Coexisting in a Male Patient","authors":"Jie Bai, Yanqing Wang, Nanjue Cao, Yan Liu, Xufei Chen, Ting He, Shan Wang","doi":"10.1155/2024/5519361","DOIUrl":"https://doi.org/10.1155/2024/5519361","url":null,"abstract":"Background Here, we report a case of a male patient with bilateral focal choroidal excavation (FCE) and central serous chorioretinopathy (CSC). A 33-year-old man complained of mild blurring of vision in the right eye. Optical coherence tomography (OCT) revealed FCE in both eyes, with subretinal fluid in both eyes and serous pigment epithelial detachment in the right eye. Standard laser fluence (50 J/cm2) was used in the right eye, and a subthreshold micropulse laser (SML) was simultaneously used in the left eye. Follow-up visits were recommended. At his last visit (5 months after treatment), the visual acuity was 16/20 in the right eye and 20/20 in the left eye and OCT showed a completed resolution of SRF. Conclusion FCE is defined as a localized depression of the choroid detected by OCT. It may be congenital or acquired secondarily. We present a case of uncommon focal choroidal excavation and central serous chorioretinopathy (CSC) coexisting in both eyes at a relatively young age in which visual acuity was improved and subretinal fluid (SRF) completely resolved with laser treatment. Timely treatment can promote SRF absorption and improve vision.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outer Retinopathies Associated with COVID-19 Infection: Case Reports and Review of Literature. 与 COVID-19 感染相关的外视网膜病变:病例报告和文献综述
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-03-08 eCollection Date: 2024-01-01 DOI: 10.1155/2024/7227086
Naima Zaheer, Mohammad O Tallouzi, N Ajith Kumar, Sreekanth Sreekantam
{"title":"Outer Retinopathies Associated with COVID-19 Infection: Case Reports and Review of Literature.","authors":"Naima Zaheer, Mohammad O Tallouzi, N Ajith Kumar, Sreekanth Sreekantam","doi":"10.1155/2024/7227086","DOIUrl":"10.1155/2024/7227086","url":null,"abstract":"<p><strong>Background: </strong>The coronavirus disease (COVID-19) is a highly contagious disease with profound health implications. It can affect any part of the body with variable severity. Various ophthalmic manifestations of coronavirus disease have been documented. <i>Case Presentations</i>. We reported three cases of outer retinopathies associated with COVID-19 infection. All three patients were young females. The first two patients presented within days of COVID-19 infection with complaints of black spots in the eyes. Multimodal retinal imaging showed lesions consistent with acute macular neuroretinopathy. Lesions were bilateral in the first patient and unilateral in the second one. Our third patient presented with blurred vision in one eye, 3 months after a suspected COVID-19 infection. Retinal imaging showed outer retinopathy. Our patients' vision was good and maintained during the follow-up. All three were monitored on observation only, and symptoms and lesions improved with time.</p><p><strong>Conclusion: </strong>In conclusion, COVID-19-related thromboinflammatory response can result in localized vascular inflammation and hypoperfusion in any of the retinal capillary plexuses or choriocapillaris resulting in ischemia of the corresponding retinal or choroidal layers.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10942824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140142791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated Ocular Relapse of Acute Myeloid Leukaemia Post Allogeneic Stem Cell Transplant. 同种异体干细胞移植后急性髓性白血病孤立性眼部复发。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-02-21 eCollection Date: 2024-01-01 DOI: 10.1155/2024/2235819
M H Tong, A Kwok, A Walsh, P Heydon, E S Koh, N McNamara, A Bryant
{"title":"Isolated Ocular Relapse of Acute Myeloid Leukaemia Post Allogeneic Stem Cell Transplant.","authors":"M H Tong, A Kwok, A Walsh, P Heydon, E S Koh, N McNamara, A Bryant","doi":"10.1155/2024/2235819","DOIUrl":"10.1155/2024/2235819","url":null,"abstract":"<p><p>We present a rare case of a 39-year-old female with extramedullary relapse of acute myeloid leukaemia (AML) isolated to the left eye 2 months post allogeneic haematopoietic stem cell transplant. She initially presented with painless left eye erythema, swelling, and visual impairment. Initial ophthalmology review revealed conjunctival chemosis, raised intraocular pressure, and serous retinal detachments. She was initially treated for suspected orbital cellulitis with intravenous antibiotic and antifungal therapy but clinically progressed so was then treated with intravenous corticosteroids. One week later, she progressed to angle-closure glaucoma with development of a hypopyon and an enlarging subconjunctival mass. She proceeded to urgent subconjunctival biopsy and drainage of subretinal fluid which confirmed extramedullary relapse of AML. Notably, further investigation found no evidence of bone marrow or central nervous system relapse. She proceeded to localized radiotherapy with gradual resolution of the subconjunctival mass and serous retinal detachment and was for consideration of donor lymphocyte infusions and azacitidine therapy; unfortunately, she developed respiratory sepsis and passed away despite maximal efforts. This case represents a rare and unusual presentation of isolated ocular extramedullary relapse of AML and emphasises the importance of early ophthalmology involvement and tissue biopsy when there is high clinical suspicion of the disease.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma. 结膜黑色素瘤完全治疗后的泪腺引流系统和鼻腔黑色素瘤
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-02-08 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1034939
Amirreza Veisi, Zahra Dastborhan, Mohsen Dastmardi, Mozhgan Rezaie Kanavi, Saeid Rezaei
{"title":"Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma.","authors":"Amirreza Veisi, Zahra Dastborhan, Mohsen Dastmardi, Mozhgan Rezaie Kanavi, Saeid Rezaei","doi":"10.1155/2024/1034939","DOIUrl":"10.1155/2024/1034939","url":null,"abstract":"<p><p>Malignant melanoma of the conjunctiva is a rare tumor of the ocular surface with potential fatal consequences and a high likelihood of recurrence. Although routes for extending the tumor, including local, hematogenous, and lymphatogenous, are pretty straightforward, the indirect extension through free-floating tumoral cells to the nasolacrimal duct is not described thoroughly. We report a case of malignant melanoma of the conjunctiva which presented with local recurrence in the intranasal cavity and lacrimal sac two years after the primary surgery (without involvement of the ocular surface and punctum on the second occasion). However, there was no evidence of distant metastasis on either occasion. This case demonstrates the possible noncontiguous spreading route of melanoma tumoral cells and highlights the need for attention to the surgical technique, and careful follow-up to detect further disease activity.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139740497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinal Ischemia as a Presenting Ocular Sign of Neurofibromatosis Type 2 视网膜缺血是神经纤维瘤病 2 型的眼部症状之一
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-01-23 DOI: 10.1155/2024/9133929
Binbin Zhao, Yan Yan
{"title":"Retinal Ischemia as a Presenting Ocular Sign of Neurofibromatosis Type 2","authors":"Binbin Zhao, Yan Yan","doi":"10.1155/2024/9133929","DOIUrl":"https://doi.org/10.1155/2024/9133929","url":null,"abstract":"Purpose. Specific retinal abnormalities of neurofibromatosis type 2 (NF2) commonly include retinal astrocytoma and combined hamartoma of the retina and retinal pigment epithelium. Vasculopathy is an uncommon manifestation of NF2. We reported an NF2 patient presenting with retinal ischemia. Observations. An 18-year-old healthy Chinese female with acute decreased vision. The fundus examination and optical coherence tomography revealed optic disc hamartoma in the right eye and paracentral acute middle maculopathy (PAMM) and cotton wool spot indicating retinal ischemia in the left eye. Brain MRI showed bilateral acoustic neuroma, parasellar meningioma, and cervical extramedullary tumor. The genetic test confirmed the diagnosis of NF2. Conclusions and Importance. Our case suggests that retinal ischemia could be the presenting sign of NF2. NF2 could be associated with retinal vasculopathy in addition to retina tumors.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139605739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal Imaging in Diagnosing Multiple Evanescent White Dot Syndrome following Human Papillomavirus Vaccine Immunization 多模态成像在诊断人类乳头瘤病毒疫苗免疫后的多发性疏散白点综合征中的应用
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-01-19 DOI: 10.1155/2024/9600771
Jing Yu, Yuying Ji, Yunkao Zeng, Huihui Li, Hailan Liao, F. Wen
{"title":"Multimodal Imaging in Diagnosing Multiple Evanescent White Dot Syndrome following Human Papillomavirus Vaccine Immunization","authors":"Jing Yu, Yuying Ji, Yunkao Zeng, Huihui Li, Hailan Liao, F. Wen","doi":"10.1155/2024/9600771","DOIUrl":"https://doi.org/10.1155/2024/9600771","url":null,"abstract":"Purpose. This study presents a case of multiple evanescent white dot syndrome (MEWDS) following the administration of the second dose of a human papillomavirus vaccine (HPV). We conducted a review of the literature on vaccine-associated MEWDS. Observations. A 23-year-old Chinese female reported central scotomata in the left eye persisting for 3 weeks. Upon further inquiry, she had received the second dose of the human papillomavirus vaccine (Gardasil-9) three days before the onset of symptoms. A diagnosis of MEWDS was established based on clinical and multimodal imaging (MMI) data. Symptoms resolved after twelve weeks of oral prednisone treatment. Conclusion and Importance. This case highlights a typical case of MEWDS closely associated with HPV vaccination, demonstrating a favorable prognosis with MMI. Given the self-limiting nature of MEWDS, there is a risk of clinical misdiagnosis or oversight. While further studies are warranted to establish a definitive link between the HPV vaccine and MEWDS, this case suggests a potential connection. Healthcare practitioners should remain vigilant regarding possible ocular side effects associated with immunizations.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139525683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Subinternal Limiting Membrane Crystalline Deposits Secondary to Terson Syndrome. 继发于特森综合征的双侧内膜下限膜结晶沉积。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2024-01-17 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8225960
Anfisa Ayalon, Eran Greenbaum, Lily Okrent Smolar, Alexander Rubowitz
{"title":"Bilateral Subinternal Limiting Membrane Crystalline Deposits Secondary to Terson Syndrome.","authors":"Anfisa Ayalon, Eran Greenbaum, Lily Okrent Smolar, Alexander Rubowitz","doi":"10.1155/2024/8225960","DOIUrl":"10.1155/2024/8225960","url":null,"abstract":"<p><strong>Background: </strong>We report the case of bilateral, subinternal limiting membrane crystalline deposits in a patient with Terson syndrome, describe the possible pathogenesis, and highlight management. <i>Case Presentation</i>. A 24-year-old male with a history of traumatic massive parenchymal and subdural frontal hemorrhage presented to our clinic seven months after a motor vehicle accident, prolonged hospitalization, and rehabilitation, complaining of decreased vision in both eyes. The Snellen visual acuity was 1/60 in the right eye, and 6/60 in the left eye. Fundus examination showed an organized white vitreous hemorrhage in both eyes with almost no view of the retina. The anterior segments were normal. He underwent a 25-gauge pars plana vitrectomy in both eyes. During the surgery, golden crescent-shaped sediment consisting of small crystals was observed under the internal limiting membrane in both eyes: anterior to the inferior temporal vascular arcade in the right eye and posterior to it in the left eye. Internal limiting membrane (ILM) peeling after staining with ILM-blue dye was performed in the left eye, where the finding involved the macula. One year after the surgery, visual acuity significantly improved to 6/8.5 on the right and 6/6 on the left. Epiretinal membrane formation was observed in the right eye, where ILM peeling was not performed.</p><p><strong>Conclusion: </strong>Subinternal limiting membrane crystalline deposit finding is a rare condition. Consider performing internal limiting membrane peeling and sediment removal in cases with macular involvement. In cases where crystals are concentrated outside of the macula, follow-up may be considered.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab 首次使用 Nivolumab 和 Ipilimumab 后的视网膜毒性
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-12-21 DOI: 10.1155/2023/9931794
A. Kilani, Efstathios Vounotrypidis, Susanna F. König, Armin Wolf
{"title":"Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab","authors":"A. Kilani, Efstathios Vounotrypidis, Susanna F. König, Armin Wolf","doi":"10.1155/2023/9931794","DOIUrl":"https://doi.org/10.1155/2023/9931794","url":null,"abstract":"Background. To present a rare case of a bilateral immune checkpoint inhibitor- (ICI-) induced photoreceptor injury with a bacillary layer detachment (BALAD) and a dissection of the photoreceptor inner and outer segment, accompanied by ICI-induced Vogt-Koyanagi-Harada- (VKH-) like uveitis after initial administration of nivolumab and ipilimumab. Case Presentation. A 52-year-old female with metastatic malignant cutaneous melanoma experiencing bilateral progressive visual acuity reduction, after treatment initiation with 1 mg/kg nivolumab and 3 mg/kg ipilimumab two weeks prior symptom onset. An extensive laboratory workup, including uveitis workup, onconeuronal and retinal antibodies, ruled out a paraneoplastic autoimmune disorder and a granulomatous disease. Furthermore, a B-scan was performed to exclude a posterior scleritis. Ensuing temporary treatment discontinuation of nivolumab and complete discontinuation of ipilimumab, treatment with high-dose systemic steroids was initiated, which resulted in alleviation of her symptoms and stability of ocular findings. Conclusions. ICIs can induce significant ocular side effects. As ocular inflammation can be well controlled using systemic steroids, treatment with ICIs can be continued whenever possible, in particular, if there is a good treatment response of the systemic malignancy.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138953299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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