Case Reports in Ophthalmological Medicine最新文献_第10页

Outer Retinopathies Associated with COVID-19 Infection: Case Reports and Review of Literature. 与 COVID-19 感染相关的外视网膜病变：病例报告和文献综述

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2024-03-08 eCollection Date: 2024-01-01 DOI: 10.1155/2024/7227086

Naima Zaheer, Mohammad O Tallouzi, N Ajith Kumar, Sreekanth Sreekantam

{"title":"Outer Retinopathies Associated with COVID-19 Infection: Case Reports and Review of Literature.","authors":"Naima Zaheer, Mohammad O Tallouzi, N Ajith Kumar, Sreekanth Sreekantam","doi":"10.1155/2024/7227086","DOIUrl":"10.1155/2024/7227086","url":null,"abstract":"Background: The coronavirus disease (COVID-19) is a highly contagious disease with profound health implications. It can affect any part of the body with variable severity. Various ophthalmic manifestations of coronavirus disease have been documented. Case Presentations. We reported three cases of outer retinopathies associated with COVID-19 infection. All three patients were young females. The first two patients presented within days of COVID-19 infection with complaints of black spots in the eyes. Multimodal retinal imaging showed lesions consistent with acute macular neuroretinopathy. Lesions were bilateral in the first patient and unilateral in the second one. Our third patient presented with blurred vision in one eye, 3 months after a suspected COVID-19 infection. Retinal imaging showed outer retinopathy. Our patients' vision was good and maintained during the follow-up. All three were monitored on observation only, and symptoms and lesions improved with time.Conclusion: In conclusion, COVID-19-related thromboinflammatory response can result in localized vascular inflammation and hypoperfusion in any of the retinal capillary plexuses or choriocapillaris resulting in ischemia of the corresponding retinal or choroidal layers.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2024 ","pages":"7227086"},"PeriodicalIF":0.9,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10942824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140142791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolated Ocular Relapse of Acute Myeloid Leukaemia Post Allogeneic Stem Cell Transplant. 同种异体干细胞移植后急性髓性白血病孤立性眼部复发。

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Case Reports in Ophthalmological Medicine Pub Date : 2024-02-21 eCollection Date: 2024-01-01 DOI: 10.1155/2024/2235819

M H Tong, A Kwok, A Walsh, P Heydon, E S Koh, N McNamara, A Bryant

{"title":"Isolated Ocular Relapse of Acute Myeloid Leukaemia Post Allogeneic Stem Cell Transplant.","authors":"M H Tong, A Kwok, A Walsh, P Heydon, E S Koh, N McNamara, A Bryant","doi":"10.1155/2024/2235819","DOIUrl":"10.1155/2024/2235819","url":null,"abstract":"We present a rare case of a 39-year-old female with extramedullary relapse of acute myeloid leukaemia (AML) isolated to the left eye 2 months post allogeneic haematopoietic stem cell transplant. She initially presented with painless left eye erythema, swelling, and visual impairment. Initial ophthalmology review revealed conjunctival chemosis, raised intraocular pressure, and serous retinal detachments. She was initially treated for suspected orbital cellulitis with intravenous antibiotic and antifungal therapy but clinically progressed so was then treated with intravenous corticosteroids. One week later, she progressed to angle-closure glaucoma with development of a hypopyon and an enlarging subconjunctival mass. She proceeded to urgent subconjunctival biopsy and drainage of subretinal fluid which confirmed extramedullary relapse of AML. Notably, further investigation found no evidence of bone marrow or central nervous system relapse. She proceeded to localized radiotherapy with gradual resolution of the subconjunctival mass and serous retinal detachment and was for consideration of donor lymphocyte infusions and azacitidine therapy; unfortunately, she developed respiratory sepsis and passed away despite maximal efforts. This case represents a rare and unusual presentation of isolated ocular extramedullary relapse of AML and emphasises the importance of early ophthalmology involvement and tissue biopsy when there is high clinical suspicion of the disease.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2024 ","pages":"2235819"},"PeriodicalIF":0.9,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lacrimal Drainage System and Nasal Cavity Melanoma after Complete Treatment of Conjunctival Melanoma. 结膜黑色素瘤完全治疗后的泪腺引流系统和鼻腔黑色素瘤

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Case Reports in Ophthalmological Medicine Pub Date : 2024-02-08 eCollection Date: 2024-01-01 DOI: 10.1155/2024/1034939

Amirreza Veisi, Zahra Dastborhan, Mohsen Dastmardi, Mozhgan Rezaie Kanavi, Saeid Rezaei

引用次数: 0

Bilateral Subinternal Limiting Membrane Crystalline Deposits Secondary to Terson Syndrome. 继发于特森综合征的双侧内膜下限膜结晶沉积。

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Case Reports in Ophthalmological Medicine Pub Date : 2024-01-17 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8225960

Anfisa Ayalon, Eran Greenbaum, Lily Okrent Smolar, Alexander Rubowitz

{"title":"Bilateral Subinternal Limiting Membrane Crystalline Deposits Secondary to Terson Syndrome.","authors":"Anfisa Ayalon, Eran Greenbaum, Lily Okrent Smolar, Alexander Rubowitz","doi":"10.1155/2024/8225960","DOIUrl":"10.1155/2024/8225960","url":null,"abstract":"Background: We report the case of bilateral, subinternal limiting membrane crystalline deposits in a patient with Terson syndrome, describe the possible pathogenesis, and highlight management. Case Presentation. A 24-year-old male with a history of traumatic massive parenchymal and subdural frontal hemorrhage presented to our clinic seven months after a motor vehicle accident, prolonged hospitalization, and rehabilitation, complaining of decreased vision in both eyes. The Snellen visual acuity was 1/60 in the right eye, and 6/60 in the left eye. Fundus examination showed an organized white vitreous hemorrhage in both eyes with almost no view of the retina. The anterior segments were normal. He underwent a 25-gauge pars plana vitrectomy in both eyes. During the surgery, golden crescent-shaped sediment consisting of small crystals was observed under the internal limiting membrane in both eyes: anterior to the inferior temporal vascular arcade in the right eye and posterior to it in the left eye. Internal limiting membrane (ILM) peeling after staining with ILM-blue dye was performed in the left eye, where the finding involved the macula. One year after the surgery, visual acuity significantly improved to 6/8.5 on the right and 6/6 on the left. Epiretinal membrane formation was observed in the right eye, where ILM peeling was not performed.Conclusion: Subinternal limiting membrane crystalline deposit finding is a rare condition. Consider performing internal limiting membrane peeling and sediment removal in cases with macular involvement. In cases where crystals are concentrated outside of the macula, follow-up may be considered.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2024 ","pages":"8225960"},"PeriodicalIF":0.7,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139563561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab 首次使用 Nivolumab 和 Ipilimumab 后的视网膜毒性

IF 0.9

Case Reports in Ophthalmological Medicine Pub Date : 2023-12-21 DOI: 10.1155/2023/9931794

A. Kilani, Efstathios Vounotrypidis, Susanna F. König, Armin Wolf

{"title":"Retinal Toxicity after Initial Administration of Nivolumab and Ipilimumab","authors":"A. Kilani, Efstathios Vounotrypidis, Susanna F. König, Armin Wolf","doi":"10.1155/2023/9931794","DOIUrl":"https://doi.org/10.1155/2023/9931794","url":null,"abstract":"Background. To present a rare case of a bilateral immune checkpoint inhibitor- (ICI-) induced photoreceptor injury with a bacillary layer detachment (BALAD) and a dissection of the photoreceptor inner and outer segment, accompanied by ICI-induced Vogt-Koyanagi-Harada- (VKH-) like uveitis after initial administration of nivolumab and ipilimumab. Case Presentation. A 52-year-old female with metastatic malignant cutaneous melanoma experiencing bilateral progressive visual acuity reduction, after treatment initiation with 1 mg/kg nivolumab and 3 mg/kg ipilimumab two weeks prior symptom onset. An extensive laboratory workup, including uveitis workup, onconeuronal and retinal antibodies, ruled out a paraneoplastic autoimmune disorder and a granulomatous disease. Furthermore, a B-scan was performed to exclude a posterior scleritis. Ensuing temporary treatment discontinuation of nivolumab and complete discontinuation of ipilimumab, treatment with high-dose systemic steroids was initiated, which resulted in alleviation of her symptoms and stability of ocular findings. Conclusions. ICIs can induce significant ocular side effects. As ocular inflammation can be well controlled using systemic steroids, treatment with ICIs can be continued whenever possible, in particular, if there is a good treatment response of the systemic malignancy.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"140 7","pages":""},"PeriodicalIF":0.9,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138953299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

XEN45 Gel Stent Combined with Healaflow Injectable Viscoelastic Implant. XEN45凝胶支架联合Healaflow可注射粘弹性种植体。

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Case Reports in Ophthalmological Medicine Pub Date : 2023-11-22 eCollection Date: 2023-01-01 DOI: 10.1155/2023/7096406

Eloy Villarreal, Eran Berkowitz, Beatrice Tiosano

{"title":"XEN45 Gel Stent Combined with Healaflow Injectable Viscoelastic Implant.","authors":"Eloy Villarreal, Eran Berkowitz, Beatrice Tiosano","doi":"10.1155/2023/7096406","DOIUrl":"10.1155/2023/7096406","url":null,"abstract":"Purpose: To introduce a potential solution for failed glaucoma surgeries by proposing an optional surgical procedure in conjunction with the use of Healaflow (Anteis S.A., Geneva, Switzerland) as a spacer, which may potentially reduce the failure rate. Case Presentation. We present the outcomes of a surgical procedure involving the inferonasal implantation of an ab interno XEN gel stent (Allergan, Dublin, Ireland) in a 74-year-old male patient who was experiencing uncontrolled advanced glaucoma in his left eye. It is important to note that the patient had previously undergone several glaucoma surgeries and procedures in the same eye. During this particular procedure, we utilized Healaflow as a spacer by implanting the stent within a subconjunctival Healaflow \"bubble.\" At 6 months postoperatively, intraocular pressure remained on target. There was no need for additional topical medications, and no change in visual acuity was observed.Conclusion: For patients with a history of unsuccessful glaucoma surgeries and who are unsuitable candidates for tube shunt procedures or transscleral diode cyclophotocoagulation, an alternative option involves implanting the XEN45 stent in the inferior nasal region in conjunction with the use of subconjunctival Healaflow. This combined approach may provide a potential solution for managing glaucoma in these patients.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"7096406"},"PeriodicalIF":0.7,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alström's Syndrome, Leber's Hereditary Optic Neuropathy, or Retinitis Pigmentosa? A Case of Misdiagnosis. Alström综合征，Leber遗传性视神经病变，还是色素性视网膜炎?误诊一例。

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Case Reports in Ophthalmological Medicine Pub Date : 2023-11-16 eCollection Date: 2023-01-01 DOI: 10.1155/2023/9409036

Palaiologos Alexopoulos, Chrysanthos Symeonidis, Tryfon Rotsos

{"title":"Alström's Syndrome, Leber's Hereditary Optic Neuropathy, or Retinitis Pigmentosa? A Case of Misdiagnosis.","authors":"Palaiologos Alexopoulos, Chrysanthos Symeonidis, Tryfon Rotsos","doi":"10.1155/2023/9409036","DOIUrl":"https://doi.org/10.1155/2023/9409036","url":null,"abstract":"A case of a patient with the Alström syndrome (AS) that was misdiagnosed as Leber's hereditary optic neuropathy or retinitis pigmentosa for 13 years is presented. AS is a rare genetic disorder caused by mutations in the ALMS1 gene. AS may lead to abnormal ciliary formation and function. AS affects metabolism, and symptomatology includes type 2 diabetes mellitus (T2DM), obesity, hypogonadism and gynecomastia in males, progressive bilateral sensorineural hearing loss, cardiomyopathy, nonalcoholic fatty liver disease (NAFLD), cirrhosis, and chronic progressive kidney disease. The onset of the above symptoms may vary significantly. The ophthalmic manifestation is early onset cone-rod dystrophy that starts as progressive vision loss, photophobia, and nystagmus in the first months of life. An accurate diagnosis may enable specialists to facilitate a significantly positive effect in the everyday life of a patient. Genetic counseling may also be recommended for these patients. Diagnosis was confirmed by DNA testing, thus highlighting its necessity in everyday practice.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"9409036"},"PeriodicalIF":0.9,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative Outcome of Combined Phacovitrectomy in Eyes with Excessive Myopia (>-30 D) 高度近视眼联合晶状体切除术后疗效分析(>- 30d)

Case Reports in Ophthalmological Medicine Pub Date : 2023-11-14 DOI: 10.1155/2023/7367922

Hua Fan, Mingming Zhang, Radouil Tzekov, Zhuyun Qian, Jiasong Yang, XiaoLin Xie, Wensheng Li

{"title":"Postoperative Outcome of Combined Phacovitrectomy in Eyes with Excessive Myopia (>-30 D)","authors":"Hua Fan, Mingming Zhang, Radouil Tzekov, Zhuyun Qian, Jiasong Yang, XiaoLin Xie, Wensheng Li","doi":"10.1155/2023/7367922","DOIUrl":"https://doi.org/10.1155/2023/7367922","url":null,"abstract":"Background. To report the outcomes of phacoemulsification combined with vitrectomy in eyes with extreme myopia (-30 diopters or more). Case Presentation. Three patients with cataract, vitreous opacities, and extreme myopia of more than -30 diopters underwent a combined surgical procedure of cataract extraction combined with vitrectomy. Postoperative refractive correction of the three cases ranged from -1.0 D to -2.5 D spherical equivalent. There was an obvious hyperopic shift of all cases. All patients noted a significant improvement in uncorrected and best-corrected visual acuity from 0.4 to 0.8 in case 1, from CF/70 cm to 1.0 in case 2, and from 0.12 to 0.5 in the right eye and 0.15 to 0.2 in the left eye in case 3. Vitreous floaters disappeared in all cases. No complications were noted during follow-up. Conclusions. To the best of the authors’ knowledge, these represent the first reported clinical cases of combined cataract extraction+vitrectomy surgery in eyes with extreme (>-30 D) myopia. Our results support the notion that phacoemulsification combined with vitrectomy may be a good therapeutic option for cataracts and vitreous floaters in cases with extreme myopia.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"102 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134957755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epikeratophakia for Keratoconus: A Case Report with 30 Years of Follow-Up 圆锥角膜表面角膜脱落1例，随访30年

Case Reports in Ophthalmological Medicine Pub Date : 2023-11-08 DOI: 10.1155/2023/9919057

Takashi Miyai, Tetsuya Toyono, Hitoha Ishii, Kohdai Kitamoto, Yukako Taketani, Takashi Ono, Makoto Aihara, Kazunori Miyata

{"title":"Epikeratophakia for Keratoconus: A Case Report with 30 Years of Follow-Up","authors":"Takashi Miyai, Tetsuya Toyono, Hitoha Ishii, Kohdai Kitamoto, Yukako Taketani, Takashi Ono, Makoto Aihara, Kazunori Miyata","doi":"10.1155/2023/9919057","DOIUrl":"https://doi.org/10.1155/2023/9919057","url":null,"abstract":"Background. Epikeratophakia is a refractive surgical procedure used to correct aphakic eyes, hyperopia, and keratoconus and is often performed in children. In this report, we present the long-term effects of epikeratophakia on the progression of keratoconus in a patient who underwent surgery. Case Presentation. The patient was a 17-year-old boy with keratoconus who had difficulty wearing hard contact lenses. As a solution, he underwent right eye epikeratophakia with a plano-powered lenticule. We followed up the patient for 30 years. Although the progression of keratoconus ceased in the operated eye, it continued in the nonoperated left eye and resulted in acute hydrops 9 years and 10 months after surgery. Subsequently, 20 years after the operation, anterior-segment optical coherence tomography was performed, which revealed that the progression of keratoconus had been interrupted in the right eye but had continued in the left eye, as evidenced by the parameters of the average and maximum keratometry and thinnest corneal thickness. Conclusions. Herein, we reported the longest follow-up to date of a case of keratoconus, in which one eye was treated with epikeratophakia. The progression of keratoconus was halted in the treated eye but continued in the nonoperated contralateral eye.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"25 16","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135391566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central Retinal Vein Occlusion with Three-Retinal Quadrant Involvement: Another Focus on Optic Disc Head Vascular Anatomy Variations. 视网膜中央静脉闭塞伴视网膜三象限受累：视盘头部血管解剖变异的另一个焦点。

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Case Reports in Ophthalmological Medicine Pub Date : 2023-10-31 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6648367

Narges Hassanpoor, Vahid Abdolrahimi, Mohamad Reza Niyousha

引用次数: 0