Joshua Pasol, Carolina G Benjamin, W David Honeycutt
{"title":"DOTATATE Scan in Meningiomatosis in a Patient With Ophthalmoplegia.","authors":"Joshua Pasol, Carolina G Benjamin, W David Honeycutt","doi":"10.1155/crop/9978785","DOIUrl":"10.1155/crop/9978785","url":null,"abstract":"<p><p>DOTATATE (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid [DOTA]-octreotate) is a compound that binds somatostatin receptors seen in tumors such as meningiomas. Here, we present a case of a patient with progressive bilateral ophthalmoplegia due to meningiomatosis involving both cavernous sinuses, which was highlighted by DOTATATE imaging. Some studies have shown DOTATATE imaging is superior to contrast-enhanced magnetic resonance imaging (MRI) in identifying extent of intraosseous meningioma growth, which has been associated with worse prognosis. DOTATATE imaging should be considered in cases of unknown diagnosis of mass lesions and lesions that are in areas not easily accessible to biopsy, such as the cavernous sinuses.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2026 ","pages":"9978785"},"PeriodicalIF":0.8,"publicationDate":"2026-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12765816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145910564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conjunctival Pyogenic Granuloma Management in Bhutan: A Case Report and Literature Review.","authors":"Chencho Gem, Jigme Jamtsho","doi":"10.1155/crop/5561728","DOIUrl":"10.1155/crop/5561728","url":null,"abstract":"<p><strong>Background: </strong>Conjunctival pyogenic granuloma is a benign vascular tumor that typically occurs following an eye injury, trauma, after an eye surgery, or during pregnancy due to hormonal changes. The granulomas are commonly seen at the traumatic or the surgical wound site, where improper wound healing leads to the formation of the granuloma. However, in some cases, the cause of the granuloma remains unknown.</p><p><strong>Case presentation: </strong>A 47-year-old female presented to the Ophthalmology Outpatient Department at the Central Regional Referral Hospital in Gelephu, Bhutan, with a progressively enlarging, reddish mass in her left eye, 2 months after pterygium excision surgery. Ocular examination revealed a pedunculated, vascular lesion on the conjunctiva consistent with a postsurgical conjunctival pyogenic granuloma. The lesion was managed successfully with complete resolution and no recurrence on follow-up.</p><p><strong>Conclusion: </strong>This case underscores the need for clinicians to recognize conjunctival pyogenic granuloma as a potential postoperative complication following pterygium excision. Early diagnosis and appropriate management can prevent recurrence and other related complications. To our knowledge, this represents one of the first such cases reported from our hospital in the past 5 years.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"5561728"},"PeriodicalIF":0.8,"publicationDate":"2025-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Orbital Compartment Syndrome Following Frontoethmoidal Mucopyocele: A Case Report.","authors":"Pablo González-De-Los-Mártires, Gonzalo Guerrero-Pérez, Iñigo Salmerón-Garmendia, Amaia Garin-Balerdi, Beatriz Elso-Echeverría, Huban Atilla","doi":"10.1155/crop/8863514","DOIUrl":"10.1155/crop/8863514","url":null,"abstract":"<p><strong>Background: </strong>The objective of this study is to describe a rare case of orbital compartment syndrome (OCS) following complicated frontoethmoidal mucopyoceles.</p><p><strong>Case presentation: </strong>This report involves a 72-year-old woman with prior functional endoscopic sinus surgery who presented with acute painful proptosis, tense eyelid swelling, and ophthalmoplegia in her left eye. Imaging revealed infected mucoceles (mucopyoceles) in the left frontal and ethmoidal sinuses with intraorbital extension. Based on clinical and radiological findings, OCS was diagnosed. Emergency management included immediate lateral canthotomy and cantholysis, followed by urgent endonasal drainage of the mucopurulent material. The patient made a full recovery, with only transient eyelid numbness.</p><p><strong>Conclusion: </strong>This case underscores the importance of prompt recognition and timely coordinated intervention in OCS to prevent irreversible visual loss and intracranial extension.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"8863514"},"PeriodicalIF":0.8,"publicationDate":"2025-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sakaorat Petchyim, Supredee Pongrujikorn, Felix Paolo J Lizarondo, Woraphong Manuskiatti
{"title":"Secondary Glaucoma Resulting From Choroidal Melanoma in a Patient With Congenital Nevus of Ota.","authors":"Sakaorat Petchyim, Supredee Pongrujikorn, Felix Paolo J Lizarondo, Woraphong Manuskiatti","doi":"10.1155/crop/1434134","DOIUrl":"10.1155/crop/1434134","url":null,"abstract":"<p><strong>Purpose: </strong>First, to report nevus of Ota accompanying ocular melanoma in Thai patients. Second, to report angle-closure glaucoma as a presentation secondary to ocular melanoma along with a pathological report giving insight into the pathophysiology of secondary glaucoma in uveal melanoma.</p><p><strong>Observations: </strong>This case describes a patient with a nevus of Ota who experienced gradual, painless vision loss in the left eye, coinciding with the nevus location. Over 7 months, the patient's vision progressively worsened, culminating in the diagnosis of rhegmatogenous retinal detachment. Tumor identification was first achieved through fundus examination at a tertiary care center, and the tumor was subsequently confirmed via ocular ultrasonography. The patient elected against eye enucleation. The patient presented again as a secondary angle-closure glaucoma resulting from ocular melanoma.</p><p><strong>Conclusions and importance: </strong>This case highlighted the importance of a rare malignant tumor that can accompany a nevus of Ota. Patient symptoms can vary from visual loss to a painful eye. Physician must be aware of the disease and include melanoma in the differential diagnosis in patients with a nevus of Ota. Thorough eye examination is important. Ocular ultrasonography is feasible, simple, and crucial for diagnosis. Accurate staging is vital for choosing the correct treatment strategy to save the patient's life.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"1434134"},"PeriodicalIF":0.8,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria J Chaves-Samaniego, Gunjan Awatramani, Nazimul Hussain
{"title":"Late Reverse Pupillary Block After Scleral Fixation With Yamane Technique: A Case Report.","authors":"Maria J Chaves-Samaniego, Gunjan Awatramani, Nazimul Hussain","doi":"10.1155/crop/3923566","DOIUrl":"10.1155/crop/3923566","url":null,"abstract":"<p><strong>Introduction: </strong>The Yamane technique is a transconjunctival, sutureless method for scleral fixation of intraocular lenses (IOL) in cases lacking capsular support. While widely adopted because of its efficacy and safety, rare late complications such as IOL subluxation have been reported. We describe a case of late-onset reverse pupillary block with recurrent IOL subluxation following Yamane fixation.</p><p><strong>Case presentation: </strong>We present a case of a 64-year-old male with a history of cataract surgery and ocular hypertension who underwent Yamane scleral IOL fixation in his left eye. Five years later, he presented with cystoid macular edema, which progressed to a full-thickness macular hole and 360° iris capture of the intraocular lens optic associated with pupillary block. He underwent pars plana vitrectomy, internal limiting membrane peeling, gas tamponade, and IOL repositioning in the sulcus. Despite initial improvement, the patient experienced multiple episodes of IOL subluxation, requiring repeated repositioning and laser iridotomy. Intraoperative findings included IOL tilt and a floppy iris. After the final repositioning, the IOL remained stable at 18-month follow-up, with intraocular pressure controlled and visual acuity partially restored.</p><p><strong>Conclusion: </strong>Although the Yamane technique is generally safe and effective, this case highlights the potential for late reverse pupillary block and recurrent IOL subluxation. Contributing factors included optic-haptic junction stress, iris instability, and improper scleral tunnel architecture. Proper case selection, careful surgical technique, and close follow-up are essential to minimize the risk of complications.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"3923566"},"PeriodicalIF":0.8,"publicationDate":"2025-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wide-Field Imaging of Retinal Vascular Macroaneurysm Associated With Retinal Racemose Hemangioma.","authors":"Yamato Katsura, Hisashi Fukuyama, Fumi Gomi","doi":"10.1155/crop/1972222","DOIUrl":"10.1155/crop/1972222","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to describe a case of exudative retinal vascular macroaneurysm (RVM) associated with retinal racemose hemangioma (RRH).</p><p><strong>Methods: </strong>The study design is an observational case report.</p><p><strong>Results: </strong>A 40-year-old woman presented with visual field defects in her right eye. Fundus examination revealed exudative RVM in combination with RRH. Subsequently, subretinal hemorrhage extended toward the macula, and her best-corrected visual acuity declined to 20/63. Treatment consisted of intravitreal bevacizumab injections and retinal photocoagulation for the RVM. This approach led to resolution of the RVM, confirmed by OCTA. Eight months after photocoagulation, her best-corrected visual acuity improved to 20/20.</p><p><strong>Conclusion: </strong>This case demonstrates the effectiveness of combined intravitreal bevacizumab injections and retinal photocoagulation for treating RVM. The resolution of the RVM was confirmed by OCTA. Wide-field OCTA is indispensable for evaluating the extent of arteriovenous malformations and for tracking post-treatment changes and complications. Considering the potential for recurrence of RVM associated with RRH, careful and ongoing follow-up is necessary.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"1972222"},"PeriodicalIF":0.8,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Presumed X-Linked Retinoschisis in a 3-Month-Old Baby Girl: A Case Report.","authors":"Hanieh Fakhredin, Esmaeil Asadi Khameneh, Shahin Faghihi, Mohammadreza Mehrabi Bahar, Fatemeh Bazvand","doi":"10.1155/crop/2850410","DOIUrl":"10.1155/crop/2850410","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study is to report a 3-month-old Iranian baby girl presenting with bilateral macular and peripheral retinoschisis with a probable diagnosis of X-linked retinoschisis (XLRS).</p><p><strong>Methods: </strong>The baby underwent an ophthalmic examination under general anesthesia revealing bilateral vitreous hemorrhage, spoke-wheel pattern radiating from the fovea, and severe bullous peripheral retinal elevation. We performed indirect scatter laser photocoagulation with a few spots, which showed a positive response confirming the diagnosis of retinoschisis over rhegmatogenous retinal detachment. Spectral-domain optical coherence tomography (SD-OCT) and intraoperative fluorescein angiography (FA) were also performed to enhance the diagnostic evaluation.</p><p><strong>Results: </strong>Based on comprehensive clinical examinations and imaging findings, XLRS was determined to be the most likely diagnosis.</p><p><strong>Conclusion: </strong>This case highlights the importance of including retinoschisis, with possible X-linked inheritance, in the differential diagnosis of bilateral schisis and vitreous hemorrhage in female infants. Although the XLRS phenotype is rare in the female population, it appears to be more severe and manifests at an earlier age. Genetic confirmation is needed to determine the exact etiology.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"2850410"},"PeriodicalIF":0.8,"publicationDate":"2025-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12747056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145862269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Secondary Angle Closure Glaucoma due to Massive Subretinal and Suprachoroidal Hemorrhage in Neovascular Age-Related Macular Degeneration: Clinical Case and Literature Review.","authors":"Kosuke Nagaoka, Shinji Makino, Satoru Inoda, Toshikatsu Kaburaki","doi":"10.1155/crop/2230622","DOIUrl":"10.1155/crop/2230622","url":null,"abstract":"<p><p>Massive subretinal hemorrhage secondary to neovascular age-related macular degeneration (nAMD) is relatively uncommon, and reports of secondary angle closure glaucoma associated with such hemorrhage are even rarer. We report a case of a 93-year-old woman with a history of nAMD who developed this condition, along with a review of the relevant literature.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"2230622"},"PeriodicalIF":0.8,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12698262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145755419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rituraj Videkar, Hassan Al Hasid, Mohammad Fazal Kamal, Gangaprasad Amula, Aneez Shaikh
{"title":"Optical Coherence Tomography (OCT) Biomarkers for Nonsurgical Management of Postvitrectomy Secondary Macular Holes With Intravitreal Triamcinolone Acetonide (1 mg/0.1 mL): A Case Report of Two Cases.","authors":"Rituraj Videkar, Hassan Al Hasid, Mohammad Fazal Kamal, Gangaprasad Amula, Aneez Shaikh","doi":"10.1155/crop/4451513","DOIUrl":"10.1155/crop/4451513","url":null,"abstract":"<p><strong>Purpose: </strong>To report optical coherence tomography (OCT) biomarkers for nonsurgical management of secondary macular holes.</p><p><strong>Case series: </strong>We report two cases in which postvitrectomy macular holes were managed with preservative-free intravitreal triamcinolone acetonide (1 mg/0.1 mL). All the patients underwent OCT examination before and after injection. Patients 1 and 2 experienced closure of the macular hole. The OCT biomarkers for the patients were (1) an apical diameter of less than 100 microns, (2) the presence of subretinal fluid, (3) the presence of a perifoveal cuff of fluid, and (4) the absence of preretinal traction.</p><p><strong>Discussion: </strong>The incidence of secondary macular holes is reported to range from 0.24% to 1.9% of patients who undergo vitrectomy. Secondary macular holes are also reported postvitrectomy due to inadvertent iatrogenic trauma, cystoid macular edema, etc. The treatment of secondary macular holes essentially involves various modifications of the ILM flap technique. There have been reports on the closure of secondary macular holes with the intravitreal injection of triamcinolone acetonide, intravitreal bevacizumab, aflibercept, NSAID, and difluprednate. The identification of OCT biomarkers prior to vitrectomy can help in targeted use of nonsurgical treatment modalities in the management of secondary macular holes with the intravitreal injection of triamcinolone acetonide (1 mg/0.1 mL).</p><p><strong>Conclusion: </strong>Identification of OCT biomarkers can help in the nonsurgical management of secondary macular holes.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"4451513"},"PeriodicalIF":0.4,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12659985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145647416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bilateral Foveal Cysts in Mucopolysaccharidosis Type I (Hurler Syndrome): Response to Acetazolamide With Insights From Multimodal Retinal Imaging and Electrophysiology.","authors":"Rashmi Lobo, Ahmed Al-Hinai, Aisha Al Busaidi","doi":"10.1155/crop/5349202","DOIUrl":"https://doi.org/10.1155/crop/5349202","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to report a case of bilateral foveal cysts in MPS I-H resolving with oral acetazolamide and to highlight the diagnostic value of multimodal retinal imaging and electrophysiological testing.</p><p><strong>Introduction: </strong>Hurler syndrome (mucopolysaccharidosis Type I-H) is a lysosomal storage disorder that can cause progressive multisystem complications. Retinal involvement often mimics retinitis pigmentosa (RP), and pathology may progress even after early hematopoietic stem cell transplantation (HSCT) due to limited enzyme penetration into ocular tissues.</p><p><strong>Case summary: </strong>A 17-year-old female with MPS I-H, post-HSCT at 21 months, presented with bilateral visual decline despite a normal clinical fundus exam. Evaluation included spectral-domain OCT (SD-OCT), fundus autofluorescence (FAF), multifocal electroretinography (mfERG), full-field ERG (ffERG), and visual evoked potential. SD-OCT revealed bilateral intraretinal foveal cysts without leakage on fluorescein angiography. FAF showed a bull's eye maculopathy pattern; mfERG showed bilateral macular dysfunction. ffERG revealed rod-cone dystrophy. Two 3-month courses of oral acetazolamide (125 mg three times daily) led to complete cyst resolution and visual improvement.</p><p><strong>Conclusion: </strong>This case supports the role of systemic carbonic anhydrase inhibitors in treating nonleaking macular cysts in MPS I, similar to RP-related cystoid macular pathologies, and highlights the value of integrating electrophysiological and multimodal imaging, especially in occult retinal disease.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2025 ","pages":"5349202"},"PeriodicalIF":0.4,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12657076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145629942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}