Case Reports in Ophthalmological Medicine最新文献_第9页

Conjunctival Tarsal Actinic Keratosis Treated with Interferon Alfa-2b: A Rare Case Report and Literature Review. 干扰素α -2b治疗结膜角膜光化性角化病1例报告及文献复习。

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Case Reports in Ophthalmological Medicine Pub Date : 2021-01-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6616021

Mónica Gimeno-Carrero, María-Jesús Suárez-Fernández, Beatriz Alonso-Martín, Almudena de-Pablo-Cabrera, María-Concepción Garrido-Ruíz, Enrique Mencía-Gutiérrez

{"title":"Conjunctival Tarsal Actinic Keratosis Treated with Interferon Alfa-2b: A Rare Case Report and Literature Review.","authors":"Mónica Gimeno-Carrero, María-Jesús Suárez-Fernández, Beatriz Alonso-Martín, Almudena de-Pablo-Cabrera, María-Concepción Garrido-Ruíz, Enrique Mencía-Gutiérrez","doi":"10.1155/2021/6616021","DOIUrl":"https://doi.org/10.1155/2021/6616021","url":null,"abstract":"Conjunctival neoplasia is one of the most frequent tumors in the eye. Actinic keratosis (AK) or solar keratosis is a precancerous lesion that is included with other epithelial tumors. This alteration does not break the basal membrane. There is enough evidence of successful outcomes to consider interferon alfa-2b (IFN alfa-2b) as the first choice of treatment for this type of tumors. In addition, side effects are mild and uncommon. We report a case in an 83-year-old woman who was referred to evaluate a leukoplakia in the tarsal conjunctiva of the lower left eyelid that measured 1 cm in diameter. Pathological study revealed AK. After the INF alfa-2b treatment, we observed conjunctival hyperemia, noninfiltrated upper nasal de-epithelization, and inferior nasal bulla. AK with presentation in conjunctiva is rarely described and in tarsal conjunctiva is exceptional. It is the first case published with only tarsal conjunctiva affectation.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":" ","pages":"6616021"},"PeriodicalIF":0.9,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25341761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Evolution of Lightning Maculopathy: Presentation of Two Clinical Cases and Brief Review of the Literature. 闪电黄斑病变的演变:两例临床报告及文献综述。

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Case Reports in Ophthalmological Medicine Pub Date : 2021-01-22 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8831987

Simanta Khadka, Raghunandan Byanju, Sangita Pradhan, Suchan Poon, Rinkal Suwal

{"title":"Evolution of Lightning Maculopathy: Presentation of Two Clinical Cases and Brief Review of the Literature.","authors":"Simanta Khadka, Raghunandan Byanju, Sangita Pradhan, Suchan Poon, Rinkal Suwal","doi":"10.1155/2021/8831987","DOIUrl":"https://doi.org/10.1155/2021/8831987","url":null,"abstract":"Lightning is a naturally occurring atmospheric phenomenon. Though uncommon, it is a potentially devastating and underreported natural calamity. Lightning accounts for the second leading cause of weather-related death in most parts of the world. Among the survivors of lightning injury, more than half of the victims may suffer from some form of ophthalmic injury. The lightning-associated ocular injury varies from a range of anterior segment to posterior segment pathologies. We report on two clinical cases of ocular injuries among the survivors of lightning injury. Anatomical involvement is seen at different levels with presentation as uveitis, pupillary abnormality, maculopathy, and later development of lenticular opacification. Optical coherence tomography (OCT), a noninvasive diagnostic tool, is particularly useful in the evaluation of lighting maculopathy as well as to monitor its progression through the course of time. Visual prognosis depends upon the structures of the eyes affected in the injury. The presence of irreversible retinal damage as well as optic nerve damage often result in poor visual outcome in the absence of significant anterior segment pathology. This report highlights the evolution of maculopathy through the course of time and signifies the importance of long-term follow-up postlightning injury.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":" ","pages":"8831987"},"PeriodicalIF":0.9,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25341762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center. Vogt-Koyanagi-Harada病:三级眼科中心的病例系列。

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Case Reports in Ophthalmological Medicine Pub Date : 2021-01-01 DOI: 10.1155/2021/8848659

Pranav Shrestha, Sadhana Sharma, Ranju Kharel

{"title":"Vogt-Koyanagi-Harada Disease: A Case Series in a Tertiary Eye Center.","authors":"Pranav Shrestha, Sadhana Sharma, Ranju Kharel","doi":"10.1155/2021/8848659","DOIUrl":"https://doi.org/10.1155/2021/8848659","url":null,"abstract":"Purpose: To study the clinical spectrum of Vogt-Koyanagi-Harada (VKH) disease in a tertiary eye center in Nepal.Methods: Baseline demographic details and clinical features of six patients diagnosed as VKH in a tertiary eye center were retrospectively reviewed. Examinations included best corrected visual acuity, intraocular pressure, and slit lamp examination of anterior and posterior segments. Baseline blood investigations, chest X-ray, fundus photography, and fundus fluorescent angiography (FFA) were performed on all the patients.Results: The mean age at presentation was 46 ± 8.43 years with female predominance (83.3%). The disease was complete in 16.7%, incomplete in 16.7%, and probable in 66.7% of the patients. Most cases presented in acute uveitis stage (66.7%). The most common finding in acute cases was serous retinal detachment (66.7%), followed by disc edema (58.3%), whereas in chronic cases, depigmented fundus was the most common. All cases had bilateral presentation.Conclusion: VKH is an important cause of bilateral loss of vision and has a good visual prognosis if aggressive treatment is initiated during the early stages.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2021 ","pages":"8848659"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7847319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10639278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis. 鳞状细胞癌伴光化性角化病的神经周围浸润及眶部侵犯一例。

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Case Reports in Ophthalmological Medicine Pub Date : 2020-12-30 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8831668

Edgard Farah, Marie Callet, Augustin Leclerc, Tryfon Rotsos, Chrysanthos Symeonidis, Pierre-Vincent Jacomet, Olivier Galatoire

{"title":"An Unusual Case of Perineural Infiltration and Orbital Invasion of Squamous Cell Carcinoma Associated with Actinic Keratosis.","authors":"Edgard Farah, Marie Callet, Augustin Leclerc, Tryfon Rotsos, Chrysanthos Symeonidis, Pierre-Vincent Jacomet, Olivier Galatoire","doi":"10.1155/2020/8831668","DOIUrl":"https://doi.org/10.1155/2020/8831668","url":null,"abstract":"Actinic keratosis is considered a precancerous lesion, constituting a precursor to squamous cell carcinoma (SCC) formation. Perineural invasion has been observed in patients with cutaneous carcinoma due to local subcutaneous tissue destruction and primarily involves the trigeminal nerve due to rich innervation provided by the supraorbital nerve in addition to the facial nerve. An unusual case of perineural infiltration and orbital invasion of squamous cell carcinoma associated with actinic keratosis is presented. A 70-year-old Caucasian woman presented with complete left eye ophthalmoplegia, total left upper-eyelid ptosis, and facial pain with paresthesia. Computed tomography revealed a process of the soft tissues in the left cheek infiltrating the infraorbital canal, pterygopalatine fossa, inferior orbital fissure, and left cavernous sinus with periosteal adherence. Magnetic resonance imaging revealed pathological extension via the left infraorbital canal with a considerable area of necrosis. Treatment of facial actinic keratosis may not prevent malignant transformation and can delay diagnosis and treatment of SCC. A deep biopsy appears to be essential for a correct diagnosis. Perineural spread of cutaneous SCC may be characterized by insidious progression in the cranial trigeminal nerve, abnormal ocular motility, diplopia, or external ophthalmoplegia.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2020 ","pages":"8831668"},"PeriodicalIF":0.9,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38855976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Recurrent Herpes Zoster Ophthalmicus Preceded by Anabolic Steroids and High-Dose L-Arginine. 蛋白同化类固醇和大剂量左旋精氨酸导致复发性带状疱疹眼炎。

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Case Reports in Ophthalmological Medicine Pub Date : 2020-12-28 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8861892

Stephen A LoBue, Adam Goldman, Richard A Giovane, Stacy M Carlson, Michael Bivona, Sinan Albear, Thomas D LoBue

{"title":"Recurrent Herpes Zoster Ophthalmicus Preceded by Anabolic Steroids and High-Dose L-Arginine.","authors":"Stephen A LoBue, Adam Goldman, Richard A Giovane, Stacy M Carlson, Michael Bivona, Sinan Albear, Thomas D LoBue","doi":"10.1155/2020/8861892","DOIUrl":"10.1155/2020/8861892","url":null,"abstract":"Purpose: To report a case of a 34-year-old male with recurrent herpes zoster ophthalmicus (HZO) preceded by a 6-week cycle of anabolic steroids and high-dose amino acid supplementation. Case Presentation. A 34-year-old man presented to our institution for left eye pain for one week associated with a vesicular rash in the V1 dermatome, respecting the midline. The patient had no significant past medical or past ocular history, including systemic immunosuppressive agents or HIV. However, prior to the onset of his symptoms the patient had completed a 6-week course of anabolic steroids including trenbolone, deca-durabolin, and testosterone as well as high-dose arginine supplementation averaging more than 40 grams a day. The best-corrected vision was 20/25 OS with slit-lamp examination remarkable for punctate staining and pseudodendrites at 6 o'clock, outside the visual axis. The patient was treated with oral acyclovir 800 mg five times a day for seven days along with prednisolone QID and moxifloxacin QID which was tapered over a month. Four months after resolution, the patient developed a recurrent HZO keratitis preceded by another cycle of anabolic steroids and amino acid supplementation.Conclusion: In vitro L-arginine supplementation has been associated with the proliferation and virulence of a variety of herpes viruses. Anabolic steroids have also been demonstrated by various studies to negatively affect cell-mediated immunity necessary to prevent viral infection. Thus, it is possible that anabolic steroids in conjunction with increased L-arginine intake may have precipitated a recurrent HZO in a previously healthy, immunocompetent individual.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2020 ","pages":"8861892"},"PeriodicalIF":0.9,"publicationDate":"2020-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38749004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endophthalmitis in Retinopathy of Prematurity after Intravitreal Aflibercept Injection. 玻璃体内注射阿非利西普后早产儿视网膜病变的眼内炎。

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Case Reports in Ophthalmological Medicine Pub Date : 2020-12-21 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8861435

Elcin Suren, Ersan Cetinkaya, Mustafa Kalayci, Sariye Elif Özyazıcı Özkan, Mehmet Fatih Kucuk, Muhammet Kazim Erol

引用次数: 4

Treatment of Recurrent Primary Cutaneous Mucinous Carcinoma of the Eyelid with Modified Wide Local Excision. 改良大面积局部切除治疗复发性眼睑原发性皮肤黏液癌。

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Case Reports in Ophthalmological Medicine Pub Date : 2020-12-18 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6668640

Stephanie M Tillit, Siva S R Iyer, Eric J Grieser, John T LiVecchi

{"title":"Treatment of Recurrent Primary Cutaneous Mucinous Carcinoma of the Eyelid with Modified Wide Local Excision.","authors":"Stephanie M Tillit, Siva S R Iyer, Eric J Grieser, John T LiVecchi","doi":"10.1155/2020/6668640","DOIUrl":"https://doi.org/10.1155/2020/6668640","url":null,"abstract":"Primary cutaneous mucinous carcinoma (PCMC) is a rare, low-grade malignant neoplasm of the sweat gland, whose history has been controversial regarding eccrine versus apocrine origin. This case report describes a 53-year-old male who presented to the University of Florida, Gainesville, ophthalmology clinic and was referred to the oculoplastics service with a painless, subcentimeter mass on the lateral right upper eyelid including the canthus, consistent with recurrent primary cutaneous mucinous carcinoma of the eyelid. Four years prior, the patient had undergone excisional biopsy of the lesion in a clinic, which revealed residual tumor, but the patient deferred further surgery at the time. The patient underwent surgical excision of the mass with reconstruction without operative complications and with negative surgical margins. PCMC is difficult to diagnose clinically due to its rarity and requires a histopathological examination for confirmation of the diagnosis. This report presents the first case in the literature of primary cutaneous mucinous carcinoma in a patient with human immunodeficiency virus (HIV). With this case report, we aim to raise awareness of primary cutaneous mucinous carcinoma as a potential part of the differential diagnosis for malignant eyelid lesions, including those present in patients with HIV.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2020 ","pages":"6668640"},"PeriodicalIF":0.9,"publicationDate":"2020-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7762644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38766597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A Solitary Choroidal Mass with Spontaneous Resolution. 一个孤立的脉络膜团与自发分解。

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Case Reports in Ophthalmological Medicine Pub Date : 2020-12-10 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8882617

Fariba Ghassemi, Nazanin Ebrahimiadib, Hamid Riazi-Esfahani, Hassan Khojasteh, Zahra Mahdizad, Elias Khalili Pour

引用次数: 0

Surgical Outcomes in Macular Telangiectasia Type 2-Related Macular Holes: A Report on Four Patients. 4例黄斑毛细血管扩张2型相关黄斑孔的手术疗效分析

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Case Reports in Ophthalmological Medicine Pub Date : 2020-12-07 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8884638

Kinza T Ahmad, Joseph Chacko, Ahmed B Sallam, David B Warner, Sami H Uwaydat

{"title":"Surgical Outcomes in Macular Telangiectasia Type 2-Related Macular Holes: A Report on Four Patients.","authors":"Kinza T Ahmad, Joseph Chacko, Ahmed B Sallam, David B Warner, Sami H Uwaydat","doi":"10.1155/2020/8884638","DOIUrl":"https://doi.org/10.1155/2020/8884638","url":null,"abstract":"Introduction: The few published studies that exist on the surgical outcomes of full-thickness macular hole (FTMH) repair in Macular Telangiectasia (MacTel) Type 2 report poor rates of hole closure of around 30%. This study is the largest case series of patients with FTMH in MacTel Type 2 and describes an 80% hole closure rate.Purpose: /.Aim: To describe the outcomes of four patients who underwent surgery for FTMH associated with MacTel Type 2.Methods: A retrospective review of clinical, surgical, and imaging data of five eyes in four patients with MacTel Type 2 FTMH who underwent pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling and 30% SF6 or 15% C3F8 gas tamponade within 3-9 months of initial vision decline.Results: Visual acuity (VA) at the time of surgery ranged from 20/50 to 20/200. Successful hole closure was achieved in four out of five eyes, and final VA ranged from 20/20 to 20/40 at follow-up visits greater than 20 months postoperatively. The single eye that did not achieve hole closure had a final VA of 20/60.Conclusion: Our case series describes higher hole closure rates and better final VA than previously published reports for macular hole surgery in patients with MacTel Type 2 FTMH.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2020 ","pages":"8884638"},"PeriodicalIF":0.9,"publicationDate":"2020-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38855977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Impurities in Drug Vials Intended for Intravitreal Medication. 玻璃体内给药药瓶中的杂质。

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Case Reports in Ophthalmological Medicine Pub Date : 2020-12-02 eCollection Date: 2020-01-01 DOI: 10.1155/2020/8824585

Lisa Pohl, Lisa Strudel, Spyridon Dimopoulos, Focke Ziemssen

{"title":"Impurities in Drug Vials Intended for Intravitreal Medication.","authors":"Lisa Pohl, Lisa Strudel, Spyridon Dimopoulos, Focke Ziemssen","doi":"10.1155/2020/8824585","DOIUrl":"https://doi.org/10.1155/2020/8824585","url":null,"abstract":"Sterility is an important prerequisite for minimizing the risk of severe vision loss due to endophthalmitis after intravitreal injections. We describe three cases series of incidents where an unclear contamination of the drug solution or syringe caused the injection process to stop and continue with a new preparation. During a period of 12 months with 30,502 intravitreal injections at a tertiary center, wherein 7,076 were of the drug Aflibercept drawn up from a glass vial, three cases of the critical incident reporting system relating to intravitreal injections were identified: (1) After a typical contact with the filter cannula, the glass of an Aflibercept vial was no longer intact. (2) In the course of another injection, there was a clear deposition of debris on the outer edge of the syringe when removing the attached filter cannula. (3) After inserting the syringe into the rubber top of the vial, a whitish particle of unclear origin was identified within the drug solution. Later, this contamination/particle was identified as part of the greyish rubber that was punched out with the cannula, according to the analyses of the material sent in and the manufacturer's investigations. Thus, even in busy clinics, visual inspection of the injection solution and materials used for impurities, preferably before and after pulling them out of a vial, must be an essential part of the injection process. Even when using ready-to-use prefilled syringes (PFS), vigilance must be kept high, knowing the risk of potential contamination.","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2020 ","pages":"8824585"},"PeriodicalIF":0.9,"publicationDate":"2020-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8142807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39034647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1