Journal of neurosurgery. Case lessons最新文献

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Anaplastic pleomorphic xanthoastrocytoma with leptomeningeal dissemination presenting with cranial neuropathy in an adult patient: illustrative case. 成人患者间变性多形性黄色星形细胞瘤伴脑脊膜弥散表现为颅神经病变:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-12 DOI: 10.3171/CASE24768
Simon A Menaker, Andre E Boyke, Serguei I Bannykh, Ziedulla Abdullaev, Lindsey B Ross, Paula Eboli
{"title":"Anaplastic pleomorphic xanthoastrocytoma with leptomeningeal dissemination presenting with cranial neuropathy in an adult patient: illustrative case.","authors":"Simon A Menaker, Andre E Boyke, Serguei I Bannykh, Ziedulla Abdullaev, Lindsey B Ross, Paula Eboli","doi":"10.3171/CASE24768","DOIUrl":"10.3171/CASE24768","url":null,"abstract":"<p><strong>Background: </strong>Anaplastic pleomorphic xanthoastrocytomas (APXAs) are rare, grade 3 malignant glial neoplasms first described as a distinct entity in the 2016 WHO classification of tumors of the CNS. They are generally seen in pediatric and young adult patients as supratentorial lesions with both solid and cystic components and have a high propensity for recurrence. APXAs occasionally demonstrate leptomeningeal dissemination (LMD) but very rarely at diagnosis.</p><p><strong>Observations: </strong>The authors describe the case of a 36-year-old male with a history of seizures and a known left temporal lesion since childhood, serially imaged and never biopsied, who presented with headache, increasingly frequent seizures, and right third nerve palsy. Imaging demonstrated significant interval enlargement of the lesion with intralesional hemorrhage and predominantly locoregional leptomeningeal enhancement. He underwent resection with gross-total resection achieved, and pathology revealed WHO grade 3 pleomorphic xanthoastrocytoma with ATG7::RAF1 fusion, 9p21 deletion, and telomerase reverse transcriptase promoter mutation, as identified by next-generation sequencing. This was followed by adjuvant whole-brain radiation therapy with boost and treatment with the MEK inhibitor cobimetinib.</p><p><strong>Lessons: </strong>APXA, an already exceedingly rare primary CNS tumor, can present unusually in older adult patients with concomitant LMD and cranial neuropathy. Advanced genomic profiling can tailor adjuvant therapy. https://thejns.org/doi/10.3171/CASE24768.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12070299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrence after improvement of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: illustrative case. 动脉瘤性蛛网膜下腔出血后脑血管痉挛改善后复发:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE25138
Takahiro Tsuchiya, Tsukasa Koike, Makoto Sakamoto, Atsumi Takenobu, Akira Teraoka
{"title":"Recurrence after improvement of cerebral vasospasm following aneurysmal subarachnoid hemorrhage: illustrative case.","authors":"Takahiro Tsuchiya, Tsukasa Koike, Makoto Sakamoto, Atsumi Takenobu, Akira Teraoka","doi":"10.3171/CASE25138","DOIUrl":"https://doi.org/10.3171/CASE25138","url":null,"abstract":"<p><strong>Background: </strong>Cerebral vasospasm (CVS) following aneurysmal subarachnoid hemorrhage (SAH) typically occurs 3-5 days after the onset of SAH, reaching its peak at day 7, and persists for 2-3 weeks. Generally, once the period of CVS is over and radiological improvement has been observed, recurrence is rare.</p><p><strong>Observations: </strong>The authors present the case of a 92-year-old female with a complaint of unconsciousness. CT showed diffuse SAH and CT angiography revealed a 9-mm right internal carotid-ophthalmic artery aneurysm. On day 1, they performed balloon-assisted coil embolization. On day 8, MR angiography (MRA) showed severe CVS in both distal middle cerebral arteries. On day 15, MRA showed complete improvement of CVS. However, on day 21, MRA showed recurrence of diffuse CVSs, particularly in the right middle cerebral artery, right vertebral artery, and basilar artery, and CVS persisted for approximately 1 week. On day 29, an improvement in the CSV was observed on MRA, and subsequent monitoring revealed no further occurrence of CVS.</p><p><strong>Lessons: </strong>Here, a novel case of recurrence after complete improvement of CVS following aneurysmal SAH is presented. Even after the period of CVS is over and radiological improvement has been observed, regular imaging follow-up remains crucial. https://thejns.org/doi/10.3171/CASE25138.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent intracranial myoepithelioma: clinical course and long-term follow-up. Illustrative case. 复发性颅内肌上皮瘤:临床病程及长期随访。说明情况。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE25136
Matthew Wierzbicki, India Shelley, Aria Mahtabfar, Kevin D Judy
{"title":"Recurrent intracranial myoepithelioma: clinical course and long-term follow-up. Illustrative case.","authors":"Matthew Wierzbicki, India Shelley, Aria Mahtabfar, Kevin D Judy","doi":"10.3171/CASE25136","DOIUrl":"https://doi.org/10.3171/CASE25136","url":null,"abstract":"<p><strong>Background: </strong>Intracranial myoepithelial carcinomas are exceedingly rare tumors associated with a poor prognosis. A review of the literature revealed only 6 published cases, none of which include follow-up longer than 2 years.</p><p><strong>Observations: </strong>A 26-year-old female presented with headaches, fatigue, and vision changes. She was found to have a rare intracranial myoepithelioma in the parafalcine region. Over the next 7 years, she experienced multiple recurrences managed with surgery and radiation therapy. The patient eventually became pregnant, and a new lesion was identified in her first trimester. Following close observation and a cesarean section, the rapidly growing lesion wasresected, and consistent with prior myoepithelioma.</p><p><strong>Lessons: </strong>The authors present the seventh case of primary, intracranial malignant myoepithelioma and the only such case with follow-up longer than 2.5 years. With aggressive management, patients navigating intracranial myoepithelial carcinoma can experience robust survival with conserved quality of life. https://thejns.org/doi/10.3171/CASE25136.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paired molecular profiling of malignant transformation of an epidermoid cyst for potential genetic drivers: illustrative case. 潜在遗传驱动的表皮样囊肿恶性转化的配对分子谱:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE24849
Paul M Harary, Yusuke S Hori, Rodas Kassu, Amit R L Persad, Armine Tayag, Louisa Ustrzynski, Sara C Emrich, Iris C Gibbs, David J Park, Steven D Chang, Juan C Fernandez-Miranda
{"title":"Paired molecular profiling of malignant transformation of an epidermoid cyst for potential genetic drivers: illustrative case.","authors":"Paul M Harary, Yusuke S Hori, Rodas Kassu, Amit R L Persad, Armine Tayag, Louisa Ustrzynski, Sara C Emrich, Iris C Gibbs, David J Park, Steven D Chang, Juan C Fernandez-Miranda","doi":"10.3171/CASE24849","DOIUrl":"https://doi.org/10.3171/CASE24849","url":null,"abstract":"<p><strong>Background: </strong>Malignant transformation of an intracranial epidermoid cyst (EC) into squamous cell carcinoma (SCC) is an exceedingly rare occurrence that is typically diagnosed on postoperative histology. The mechanisms underlying transformation remain poorly understood, with limited characterization of genetic changes associated with progression.</p><p><strong>Observations: </strong>A 55-year-old female presented with a large cerebellopontine angle EC with an enhancing nodule in the left tectum, for which she underwent resection. Three months following surgery, rapid enlargement of the residual tectal component required reoperation, with pathology showing SCC. Paired next-generation sequencing of the EC and SCC revealed multiple shared variants, including a pathogenic TP53 mutation. Additionally, the SCC contained a pathogenic PTEN variant absent in the EC, suggesting a second driver mutation contributing to malignant transformation of an EC (MTEC). Her SCC was resistant to volumetric modulated arc therapy, requiring subsequent chemotherapy and pembrolizumab combined with stereotactic radiosurgery. Despite a favorable initial response, she died 26 months following MTEC diagnosis.</p><p><strong>Lessons: </strong>To the authors' knowledge, this represents the first use of paired molecular profiling to link intracranial SCC to an EC precursor, enhancing precision of this rare diagnosis. Additionally, this case identifies specific genetic alterations associated with transformation, providing insight into the largely unknown mechanisms underlying MTEC. https://thejns.org/doi/10.3171/CASE24849.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Venous sinus stenting for patients with encephaloceles: illustrative cases. 脑膨出患者静脉窦支架置入术:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE24855
Jeremy A Yarden, Patrick J Codd, Ralph Abi Hachem, Erik F Hauck
{"title":"Venous sinus stenting for patients with encephaloceles: illustrative cases.","authors":"Jeremy A Yarden, Patrick J Codd, Ralph Abi Hachem, Erik F Hauck","doi":"10.3171/CASE24855","DOIUrl":"https://doi.org/10.3171/CASE24855","url":null,"abstract":"<p><strong>Background: </strong>Idiopathic intracranial hypertension (IIH) and venous sinus stenosis have recently been implicated in the pathogenesis of encephaloceles.</p><p><strong>Observations: </strong>Here, the authors present 2 cases in which venous sinus stenting was crucial for symptom management either after surgical repair of an encephalocele or as a stand-alone treatment.</p><p><strong>Lessons: </strong>Venous sinus stenting is emerging as a novel treatment option in the management of encephaloceles associated with IIH. https://thejns.org/doi/10.3171/CASE24855.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of cutaneous scalp complications in deep brain stimulation: illustrative cases. 脑深部刺激术中皮头皮并发症的处理:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE24833
Gabrielle A Magnant, Olivier Darbin, Kelsey McKee, Anthony Martino
{"title":"Management of cutaneous scalp complications in deep brain stimulation: illustrative cases.","authors":"Gabrielle A Magnant, Olivier Darbin, Kelsey McKee, Anthony Martino","doi":"10.3171/CASE24833","DOIUrl":"https://doi.org/10.3171/CASE24833","url":null,"abstract":"<p><strong>Background: </strong>Scalp complications following deep brain stimulation (DBS) procedures can lead to hardware removal, posing significant clinical and economic challenges. This report describes 3 cases managed with adjacent tissue rearrangement flap and full-thickness skin graft procedures, along with antibiotic therapy.</p><p><strong>Observations: </strong>Among the 3 cases, 2 patients presented with local infections on initial evaluation. Six months postreconstruction, scalp complications had resolved in 2 patients without interruption to neuromodulation therapy. Of these 2 patients, one had an active infection at the initial presentation.</p><p><strong>Lessons: </strong>Contrary to the prevailing assumption that DBS hardware should be removed in the presence of scalp complications associated with active infection, the authors' findings suggest that hardware can sometimes be preserved. With comprehensive management, including empirical antibiotic therapy, the authors observed that alternative approaches to hardware removal could be valuable for patients at risk of losing DBS therapeutic benefits. https://thejns.org/doi/10.3171/CASE24833.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reclassification of pineal tumor as high-grade astrocytoma with piloid features through methylation profiling: illustrative case. 通过甲基化分析将松果体肿瘤重新分类为具有核样特征的高级别星形细胞瘤:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE24778
Alper Dincer, Miri Kim, Zeynep Hüseyinoglu, Miguel Millares Chavez, Declan McGuone, Jennifer Moliterno
{"title":"Reclassification of pineal tumor as high-grade astrocytoma with piloid features through methylation profiling: illustrative case.","authors":"Alper Dincer, Miri Kim, Zeynep Hüseyinoglu, Miguel Millares Chavez, Declan McGuone, Jennifer Moliterno","doi":"10.3171/CASE24778","DOIUrl":"https://doi.org/10.3171/CASE24778","url":null,"abstract":"<p><strong>Background: </strong>The recent WHO 2021 CNS classification system defines new tumor types and subtypes based on molecular features. Among them, high-grade astrocytoma with piloid features (HGAP) is a glioma subtype whose classification depends on its DNA methylation profiling signature. These tumors can have a varied histological appearance and are often misclassified.</p><p><strong>Observations: </strong>A 41-year-old male presented with right-sided weakness and headache. MRI detected a heterogeneously enhancing mass in the pineal region. The patient underwent an endoscopic third ventriculostomy, and a biopsy sample was obtained. The pathology was initially consistent with a high-grade neuroepithelial tumor. Repeat imaging 3 weeks postoperatively demonstrated an interval increase in tumor size. He underwent a suboccipital craniectomy for gross-total resection. DNA methylation profiling was performed and was consistent with the diagnosis of HGAP. The patient was given chemoradiotherapy due to the high-grade pathology.</p><p><strong>Lessons: </strong>Integration of molecular pathology has led to crucial and clinically relevant changes in CNS tumor classification. Utilizing these advanced diagnostic techniques to classify tumors could lead to changes in management, targeted therapeutics, and enrollment in clinical trials. https://thejns.org/doi/10.3171/CASE24778.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Five aneurysms in the posterior circulation associated with moyamoya disease: illustrative case. 后循环动脉瘤与烟雾病相关的5例:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE24848
Yao Anhui, Liyun Jia, Wei Huang, Yu Fu, Fuqiang Cao, Zhennan Hou, Benhan Wang, Xiaodong Guo
{"title":"Five aneurysms in the posterior circulation associated with moyamoya disease: illustrative case.","authors":"Yao Anhui, Liyun Jia, Wei Huang, Yu Fu, Fuqiang Cao, Zhennan Hou, Benhan Wang, Xiaodong Guo","doi":"10.3171/CASE24848","DOIUrl":"https://doi.org/10.3171/CASE24848","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of aneurysm formation in adults with moyamoya disease (MMD) is higher than that in the general population. The treatment strategy is often individualized based on the patient's disease characteristics.</p><p><strong>Observations: </strong>The authors report the case of a man who presented with an intraparenchymal hemorrhage. Cerebral angiography showed a typical MMD pattern characterized by occlusion and severe stenosis at the terminal portions of the bilateral internal carotid arteries, accompanied by moyamoya-like vasodilation. The bilateral posterior cerebral arteries (PCAs) had collateral blood supply to the anterior circulation, and 5 aneurysms were observed, which is rare. Considering that revascularization through bypass surgery could alter the hemodynamic stresses associated with MMD, the authors performed bilateral extracranial-intracranial bypass surgeries to reconstruct the anterior circulation and reduce the blood flow burden on the vertebrobasilar system. Follow-up imaging demonstrated improved cerebral perfusion in both hemispheres. Importantly, 3 of the 5 aneurysms remained stable, 1 aneurysm had shrunk, and the other had completely resolved.</p><p><strong>Lessons: </strong>For stable patients with cerebral hemorrhage, CT angiography is recommended before treatment. In surgery of patients with MMD-associated hemorrhage, avoid using artificial dura mater as it can hinder external carotid circulation and complicate future bypass procedures. https://thejns.org/doi/10.3171/CASE24848.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric cerebral arteriovenous malformation diagnosed 11 years after neonatal thalamic hemorrhage: illustrative case. 小儿脑动静脉畸形诊断后11年新生儿丘脑出血:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE25124
Yoshiki Mochizuki, Takuma Maeda, Hidetoshi Ooigawa, Masahito Kobayashi, Hiroki Kurita
{"title":"Pediatric cerebral arteriovenous malformation diagnosed 11 years after neonatal thalamic hemorrhage: illustrative case.","authors":"Yoshiki Mochizuki, Takuma Maeda, Hidetoshi Ooigawa, Masahito Kobayashi, Hiroki Kurita","doi":"10.3171/CASE25124","DOIUrl":"https://doi.org/10.3171/CASE25124","url":null,"abstract":"<p><strong>Background: </strong>Arteriovenous malformations (AVMs) are known as congenital vascular disorders. However, ruptured AVMs in neonates are extremely rare. A hypothesis suggests that micro-AVM or de novo AVMs enlarge during childhood, eventually acquiring the pathological features of adult AVMs. The authors describe a case of a pediatric AVM diagnosed 11 years after neonatal intracerebral hemorrhage.</p><p><strong>Observations: </strong>A 16-day-old neonate presented with sudden vomiting and convulsions. CT revealed a left thalamic hemorrhage extending into the left lateral ventricle. MRI showed no bleeding sources, including AVMs. By the age of 3 years, the patient developed West syndrome and was administered multiple antiseizure medication. At 5 years of age, the patient experienced convulsive status epilepticus, primarily on the right side of his body. A focal impaired awareness seizure due to the previous hemorrhage was considered. The patient remained seizure free until 11 years of age, when generalized seizures developed. MRI revealed a left thalamic AVM classified as Spetzler-Martin grade IV. The patient has been scheduled to undergo stereotactic radiosurgery.</p><p><strong>Lessons: </strong>Pediatric AVMs can undergo dynamic changes, including enlargement and de novo formation, acquiring the pathological features of adult AVMs. AVMs should be considered as a potential source of neonatal intracranial hemorrhage, necessitating long-term follow-up. https://thejns.org/doi/10.3171/CASE25124.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamic vertebral artery recanalization as a cause for recurrent posterior circulation thromboembolic stroke: illustrative case. 动态椎动脉再通作为复发性后循环血栓栓塞性中风的原因:说明性病例。
Journal of neurosurgery. Case lessons Pub Date : 2025-05-05 DOI: 10.3171/CASE25133
Hussein A Zeineddine, Gabriel Galan Castro, Antonio Dono, William W Wroe, Salvatore A D'Amato, Duncan Trimble, Nimer Adeeb, Andrew Barreto, Spiros L Blackburn
{"title":"Dynamic vertebral artery recanalization as a cause for recurrent posterior circulation thromboembolic stroke: illustrative case.","authors":"Hussein A Zeineddine, Gabriel Galan Castro, Antonio Dono, William W Wroe, Salvatore A D'Amato, Duncan Trimble, Nimer Adeeb, Andrew Barreto, Spiros L Blackburn","doi":"10.3171/CASE25133","DOIUrl":"https://doi.org/10.3171/CASE25133","url":null,"abstract":"<p><strong>Background: </strong>Posterior circulation strokes comprise one-fourth of ischemic strokes and can arise from many causes. One rare etiology is transient occlusion of the vertebral artery (VA) with head rotation due to an osteophyte, termed bow hunter's syndrome. The authors present the case of recurrent thromboembolic posterior strokes secondary to transient reopening of an osteophyte-occluded VA.</p><p><strong>Observations: </strong>A 71-year-old man presented with dizziness and visual changes with a history of prior cervical fusion and myocardial ischemia, controlled with Plavix and aspirin. CT angiography of the neck revealed osteophyte occlusion of the right VA at C4, and MRI revealed a right posterior cerebral artery (PCA) infarct. The patient was discharged on Plavix and aspirin but returned 5 months later with worsening dizziness and visual changes. MRI revealed a new left PCA infarct, leading to repeat angiography. Movement of the head during the procedure recanalized the occluded VA from before. This prompted a diagnosis of thromboembolic stroke resulting from the reopening of the occluded VA with various head movements.</p><p><strong>Lessons: </strong>This case demonstrates the utility of dynamic cerebral angiography due to the ability to manipulate head position while visualizing blood flow. Despite the invasive nature of the procedure, it helped improve diagnostic accuracy and identify a rare vascular lesion. https://thejns.org/doi/10.3171/CASE25133.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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