Joseph Rajasekaran, Rajan Thakore, Rohaid Ali, Hael Abdulrazeq, Carlin Chuck, Deus Cielo, Clark C Chen, Prakash Sampath
{"title":"Robot-assisted trigeminal nerve rhizotomy with radiofrequency ablation using Globus ExcelsiusGPS: illustrative case.","authors":"Joseph Rajasekaran, Rajan Thakore, Rohaid Ali, Hael Abdulrazeq, Carlin Chuck, Deus Cielo, Clark C Chen, Prakash Sampath","doi":"10.3171/CASE2510","DOIUrl":"10.3171/CASE2510","url":null,"abstract":"<p><strong>Background: </strong>Trigeminal neuralgia (TN) is a disorder of chronic facial pain and can be treated by radiofrequency ablation (RFA) rhizotomy of the trigeminal nerve. The use of robotic systems like the Globus ExcelsiusGPS may enhance precision and safety in intracranial procedures.</p><p><strong>Observations: </strong>A 58-year-old male with a history of TN unresponsive to multiple treatments, including microvascular decompression (MVD) and Gamma Knife radiosurgery, underwent robot-assisted RFA rhizotomy. The Globus ExcelsiusGPS robot was used to guide a needle precisely to the gasserian ganglion through the foramen ovale. The needle's trajectory was confirmed via intraoperative CT, and RFA was performed at 70°C for 90 seconds. The procedure was well tolerated with no complications. The patient reported immediate improvement in left-sided facial pain postoperatively and was discharged the following day. At the 2-week follow-up, the patient showed resolution of preoperative symptoms. The successful implementation of robot-assisted RFA rhizotomy using the Globus ExcelsiusGPS robot for TN resulted in significant pain relief and minimal complications.</p><p><strong>Lessons: </strong>This report demonstrates the potential of robot-assisted RFA in improving surgical precision, control, and patient outcomes in TN treatment. Further investigation into the long-term efficacy and safety of this innovative approach is warranted to fully understand its benefits and accuracy. https://thejns.org/doi/10.3171/CASE2510.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Belal Neyazi, Vanessa Magdalena Swiatek, Roland Schwab, Christian Mawrin, Klaus-Peter Stein, Ali Rashidi, Daniel Behme, I Erol Sandalcioglu
{"title":"When an aneurysm pretends to be a tumor: thrombosed posterior inferior cerebellar artery aneurysm mimicking a neoplasm in a pediatric patient. Illustrative case.","authors":"Belal Neyazi, Vanessa Magdalena Swiatek, Roland Schwab, Christian Mawrin, Klaus-Peter Stein, Ali Rashidi, Daniel Behme, I Erol Sandalcioglu","doi":"10.3171/CASE2592","DOIUrl":"10.3171/CASE2592","url":null,"abstract":"<p><strong>Background: </strong>Thrombosed intracranial aneurysms are rare in pediatric populations and pose significant diagnostic challenges due to their atypical imaging features, which often mimic neoplasms. These lesions can present with mass effect, contrast enhancement, and calcifications, leading to potential misdiagnosis and inappropriate management. Accurate differentiation through advanced imaging is essential to prevent surgical complications and ensure optimal outcomes.</p><p><strong>Observations: </strong>The authors describe the case of a 15-year-old boy with severe acute headaches and an MRI finding of a contrast-enhancing lesion in the left cerebellar tonsil abutting the medulla oblongata, suggestive of a neoplasm. Neurological examination was normal, and there was no significant medical history. Despite negative angiographic findings, the unclear etiology warranted surgical intervention. A median suboccipital craniotomy revealed a capsule-like lesion with arterial feeders from the posterior inferior cerebellar artery. Complete resection was achieved, and histopathology confirmed a thrombosed aneurysm. Postoperative recovery was uneventful, and 1-year follow-up showed full symptom resolution without recurrence.</p><p><strong>Lessons: </strong>This case highlights the importance of considering thrombosed aneurysms in pediatric patients with atypical intracranial lesions. Multidisciplinary collaboration and advanced imaging are crucial for accurate diagnosis and effective management. Documenting such cases enhances understanding, refines diagnostic strategies, and improves patient care. https://thejns.org/doi/10.3171/CASE2592.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marc Fischer, Kim Harnisch, Elisabeth Rushing, Javier Fandino, Attill Saemann
{"title":"A schwannoma look-alike: solitary fibrous tumor of the cauda equina. Illustrative case.","authors":"Marc Fischer, Kim Harnisch, Elisabeth Rushing, Javier Fandino, Attill Saemann","doi":"10.3171/CASE2585","DOIUrl":"10.3171/CASE2585","url":null,"abstract":"<p><strong>Background: </strong>Solitary fibrous tumors (SFTs) and schwannomas are two types of spinal neoplasms that pose significant challenges in differentiation when utilizing the preferred diagnostic modality for suspected spinal lesions, MRI. While schwannomas are generally subject to observation, particularly when presenting with asymptomatic or oligosymptomatic manifestation. SFTs require more immediate therapeutic intervention, due to their potentially aggressive characteristics and associated risk of patient harm if they are not thoroughly resected and addressed early.</p><p><strong>Observations: </strong>A 79-year-old patient was referred to the authors' clinic after receiving a diagnosis of schwannoma of the cauda equina 3 years earlier. Because of the oligosymptomatic presentation, the attending physician then implemented a watch-and-wait approach. A gross-total resection (GTR) was undertaken following progressive enlargement observed on successive MR images. The definitive pathological diagnosis revealed a grade 1 SFT.</p><p><strong>Lessons: </strong>Spinal SFT should be regarded as a potentially aggressive neoplasm characterized by an invasive propensity toward adjacent structures as well as distal metastases. The adoption of conservative management for ambiguous lesions may increase the risk of an adverse outcome. Therefore, in the context of uncertain spinal lesions with inconclusive MRI findings, it may be advisable to proceed with GTR in conjunction with confirmation of the definitive pathological diagnosis. https://thejns.org/doi/10.3171/CASE2585.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco Call-Orellana, Romulo Augusto Andrade de Almeida, Esteban Ramirez-Ferrer, Juan P Zuluaga-Garcia, Maria A Gubbiotti, Robert Y North
{"title":"Malignant mimic: pulmonary actinomycosis with contiguous vertebral involvement and spinal cord compression. Illustrative case.","authors":"Francisco Call-Orellana, Romulo Augusto Andrade de Almeida, Esteban Ramirez-Ferrer, Juan P Zuluaga-Garcia, Maria A Gubbiotti, Robert Y North","doi":"10.3171/CASE25175","DOIUrl":"10.3171/CASE25175","url":null,"abstract":"<p><strong>Background: </strong>Actinomycosis is a rare, globally distributed disease with an annual incidence of 1 case per 300,000 persons. It classically manifests as a cervicofacial disease with sinus tract formation and purulent discharge with or without sulfur granules. Spinal compromise occurs in less than 5% of cases; however, it causes significant morbidity associated with neurological impairment.</p><p><strong>Observations: </strong>This case report presents a patient with thoracic actinomycosis invading the spinal column who presented with symptoms and imaging findings mimicking malignancy. Surgery was performed, and frozen section suggested infectious etiology. Diagnostic workup and targeted management improved the clinical status of the patient at the 3-month follow-up.</p><p><strong>Lessons: </strong>The differential diagnosis when dealing with spinal column lesions should include infectious etiologies. Intraoperative frozen section and Gram stain can be critical for a timely diagnosis and to avoid jeopardizing the clinical status of patients. Surgical management can be necessary when vertebral body destruction with neural compression is present. https://thejns.org/doi/10.3171/CASE25175.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faith S Kim, Christopher Hurtado, Jennifer S Nelson, Teerin Meckmongkol, Andrea G Scherer, Sofia E Salazar, Tamarah Westmoreland
{"title":"Management of a pediatric neuroenteric cyst with persistent double dorsal aortae and anterior meningocele: illustrative case.","authors":"Faith S Kim, Christopher Hurtado, Jennifer S Nelson, Teerin Meckmongkol, Andrea G Scherer, Sofia E Salazar, Tamarah Westmoreland","doi":"10.3171/CASE24894","DOIUrl":"10.3171/CASE24894","url":null,"abstract":"<p><strong>Background: </strong>Neuroenteric cysts are exceedingly rare congenital anomalies. Although the exact pathogenesis is incompletely understood, neuroenteric cysts can arise when foregut duplication cysts extend into the spinal canal. This process is likely related to failure of endodermal cell separation from ectodermal counterparts during week 3 of development, and symptoms depend on location and degree of encroachment on surrounding structures. Complete resection remains the treatment of choice with the lowest incidence of recurrence, but the optimal surgical approach is debated. Associated congenital anomalies can add surgical complexity.</p><p><strong>Observations: </strong>The authors present the case of a 7-week-old infant diagnosed with a large mediastinal extradural neuroenteric cyst, along with multiple other congenital anomalies. A combined thoracic and laparoscopic abdominal approach was required for complete resection.</p><p><strong>Lessons: </strong>This case illustrates the importance of multispecialty collaboration, advanced imaging for preoperative planning, and thoughtful timing of intervention. A combined thoracoscopic/thoracotomy and laparoscopic approach, while surgically demanding, was safe and provided excellent visibility for complete resection of the large neuroenteric cyst. https://thejns.org/doi/10.3171/CASE24894.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metastatic choriocarcinoma after a rupture of neoplastic cerebral aneurysm with dural and brain parenchymal lesions: illustrative case.","authors":"Sho Tamai, Masashi Kinoshita, Junpei Iwadare, Kouichi Misaki, Mitsutoshi Nakada","doi":"10.3171/CASE2564","DOIUrl":"10.3171/CASE2564","url":null,"abstract":"<p><strong>Background: </strong>Although choriocarcinoma can metastasize to the brain, it is extremely rare for it to present with multiple types of metastatic lesions simultaneously.</p><p><strong>Observations: </strong>A 32-year-old primiparous woman presented with acute left-sided hemiparesis. Imaging revealed multiple intracranial and systemic lesions, including a hemorrhagic lesion with spindle-shaped vasodilatation, a dural mass, a brain parenchymal lesion, and a lung tumor. Craniotomy was performed on the dural lesion and dilated cerebral vessels, leading to the diagnosis of dural metastasis and a neoplastic cerebral aneurysm (NCA) secondary to choriocarcinoma. The patient underwent multidrug chemotherapy, which resulted in the complete resolution of all lesions. Pathological analysis confirmed that both the dural metastasis and the NCA were characterized by tumor cell invasion of vascular structures.</p><p><strong>Lessons: </strong>Choriocarcinoma can present with various types of brain metastases. In this case, both dural metastasis and NCA arose from tumor cell thrombosis, with variations in pathology likely influenced by differences in vascular structures. https://thejns.org/doi/10.3171/CASE2564.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Breanna L Sheldon, Jerry M Brown, Hasan Ozgur, Richard V Chua
{"title":"Symptomatic cerebral spinal fluid leak (or intracranial hypotension) due to sacral extradural cyst rupture after sacral fracture: illustrative case.","authors":"Breanna L Sheldon, Jerry M Brown, Hasan Ozgur, Richard V Chua","doi":"10.3171/CASE2555","DOIUrl":"10.3171/CASE2555","url":null,"abstract":"<p><strong>Background: </strong>Intracranial hypotension due to a CSF leak has many possible etiologies including traumatic dural tears, CSF-venous fistulas, iatrogenic causes, and elevated intracranial pressure. An example of traumatic rupture of a preexisting congenital spinal cyst (SC) in the sacrum causing a symptomatic CSF leak has not been described in the literature; therefore, the authors present the case of a 13-year-old female with a previously undiagnosed SC (Nabor type IB, sacral meningocele) found to have symptomatic intracranial hypotension following a ground-level fall.</p><p><strong>Observations: </strong>Traumatic rupture of SCs may cause a dural tear, resulting in stigmata of intracranial hypotension.</p><p><strong>Lessons: </strong>SCs are rare entities that are often asymptomatic but should be carefully considered in the differential diagnoses for intracranial hypotension, even following low-impact trauma. Symptoms resolve with definitive treatment of dural tear, and recurrence rates are low. https://thejns.org/doi/10.3171/CASE2555.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua M Venegas, Noah L A Nawabi, Aaron Miller, Tiffany Baker, Scott Lindhorst, Alicia Zukas, Charlotte Rivers, William Vandergrift, Ben A Strickland
{"title":"Leptomeningeal hemangioblastoma: illustrative case.","authors":"Joshua M Venegas, Noah L A Nawabi, Aaron Miller, Tiffany Baker, Scott Lindhorst, Alicia Zukas, Charlotte Rivers, William Vandergrift, Ben A Strickland","doi":"10.3171/CASE25204","DOIUrl":"10.3171/CASE25204","url":null,"abstract":"<p><strong>Background: </strong>Hemangioblastoma is a slow-growing vascular tumor commonly found in the posterior fossa. It is associated with von Hippel-Lindau disease, yet most cases arise sporadically. Resection and belzutifan are highly effective in the treatment of hemangioblastoma. Rarely, leptomeningeal dissemination may occur months to years after resection.</p><p><strong>Observations: </strong>A 56-year-old female with cerebellar hemangioblastoma resected in 2016 presented 8 years later with left hemiparesis. Updated neuroimaging revealed new leptomeningeal disease, confirmed via tissue from a right cerebellopontine angle mass. The authors conducted a review of 33 patients diagnosed with leptomeningeal disease; two-thirds were male with a median age of 48 years. Thirty-two patients presented initially with a solitary mass, and 96% of these underwent resection. The mean time from initial lesion resection to dissemination was 94 months.</p><p><strong>Lessons: </strong>After resection, hemangioblastoma recurrence with leptomeningeal spread is a rare but dangerous possible complication. Management is complex, yet a combination of pan-CNS radiation therapy, targeted resection, and belzutifan (a small-molecule inhibitor that selectively targets and blocks the function of HIF-2α) may represent an effective treatment combination. https://thejns.org/doi/10.3171/CASE25204.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intramedullary schwannoma mimicking ependymoma: illustrative case.","authors":"Takayasu Ando, Hisaaki Uchikado, Natsuko Miyahara, Satoshi Nagase, Takehiro Makizono, Jin Kikuchi, Gohsuke Hattori, Motohiro Morioka","doi":"10.3171/CASE25127","DOIUrl":"10.3171/CASE25127","url":null,"abstract":"<p><strong>Background: </strong>Most intramedullary spinal cord tumors are gliomas such as astrocytoma and ependymoma. Intramedullary schwannoma is rare.</p><p><strong>Observations: </strong>A 73-year-old woman presented with slowly progressive leg numbness and disturbed gait. A T10-11 intramedullary ependymoma was diagnosed by contrast-enhanced MRI. Tumor resection was performed via the posterior median sulcus approach under electrophysiological monitoring. Tumor pathology was schwannoma. After surgery, the patient's modified McCormick Scale grade worsened (grade II to grade III).</p><p><strong>Lessons: </strong>Spinal cord ependymoma should be suspected if the posterior median sulcus is displaced. A posterolateral sulcus approach should be considered in such cases. https://thejns.org/doi/10.3171/CASE25127.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ubong U Ekpene, Ned M Ndafia, Enono E Uduehe, Nsese Udeme, Uyi Usoro, Ernest J Barthélemy, Timothy E Nottidge
{"title":"Management outcome of a patient with a self-inflicted multiple intracranial nail impalement in a tertiary hospital in Uyo: illustrative case.","authors":"Ubong U Ekpene, Ned M Ndafia, Enono E Uduehe, Nsese Udeme, Uyi Usoro, Ernest J Barthélemy, Timothy E Nottidge","doi":"10.3171/CASE25103","DOIUrl":"10.3171/CASE25103","url":null,"abstract":"<p><strong>Background: </strong>Intracranial nail impalement injury is a rare type of low-energy penetrating brain injury resulting from the forceful entry of a nail into the cranial cavity without exiting it. Clinical outcome depends on the number of impaling nails, the depth of penetration, the extent of the primary brain injury, associated vascular injury, and prompt surgical management to limit secondary injuries. The authors report a case and the management outcome in a low-middle-income country.</p><p><strong>Observations: </strong>A 27-year-old man was reportedly found by his relatives on the floor of his room, having generalized tonic-clonic seizures, and was brought to the University of Uyo Teaching Hospital. He was resuscitated, and an urgent cranial CT scan was performed that showed seven fully implanted, nail-shaped foreign bodies. He underwent emergency craniotomy with extraction of seven 3-inch nails. Brisk bleeding encountered from the injured superior sagittal sinus was controlled effectively. In the postoperative period, he developed nail tracks abscesses that were treated with antibiotics for 6 weeks. He had an excellent recovery with no neurological deficit and was discharged home.</p><p><strong>Lessons: </strong>Multiple intracranial nail impalement injuries, although life-threatening, can be treated with excellent outcome following prompt treatment, meticulous surgical technique, and appropriate duration of antibiotics. https://thejns.org/doi/10.3171/CASE25103.</p>","PeriodicalId":94098,"journal":{"name":"Journal of neurosurgery. Case lessons","volume":"9 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}