BMC Urology最新文献

{"title":"Comparison of the effectiveness of single-dose levofloxacin with single-dose fosfomycin pre-urodynamic study related to the incidence of urinary tract infection: a randomized controlled trial.","authors":"Harrina Erlianti Rahardjo, Fina Widia, Cindy Wijaya, Kevin Leonardo, Alfred Tanjung, Muhammad Hanif Arfiananda, Fatimah Nuwwaaridya Fitriani, Rahmat Aidil Fajar Siregar, Andika Afriansyah","doi":"10.1186/s12894-025-01839-y","DOIUrl":"10.1186/s12894-025-01839-y","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"172"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of Pan-Immune inflammation value and systemic Immune-Inflammation index as potential biomarkers in predicting infectious complications following retrograde intrarenal surgery.","authors":"Bedreddin Kalyenci, Ferhat Çoban, Hasan Sulhan, Mehmet Özgür Yücel, Can Benlioğlu, Gazi Kaz, Tayfun Şahinkanat, Ali Çift","doi":"10.1186/s12894-025-01859-8","DOIUrl":"10.1186/s12894-025-01859-8","url":null,"abstract":"<p><strong>Background: </strong>To predict postoperative infectious complications by utilizing hemogram parameters and derived inflammation indices and to analyze patient-related risk factors to propose a nomogram.</p><p><strong>Methods: </strong>The data of patients who underwent retrograde intrarenal surgery were reviewed. The patients were categorized into two groups: those without infectious complications (Group A) and those with infectious complications (Group B). Infectious complications were defined as fever persisting above 38 °C for 48 h and the presence of two or more systemic inflammatory response syndrome (SIRS) criteria. Hemogram parameters and inflammation indices were examined to predict infectious complications. The study utilized neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR), along with the pan-immune-inflammation value (PIV) and systemic immune-inflammation index (SII).</p><p><strong>Results: </strong>The data of 658 cases were evaluated. No infectious complications were observed in 610 cases (92.7%), while 33 cases (5.0%) developed fever, and 15 cases (2.3%) met the criteria for SIRS. The optimal cut-off values for distinguishing between groups were determined as follows: >2.66 for NLR, > 122.5 for PLR, < 2.81 for LMR, > 619.4 for SII, and > 500.2 for PIV. Patients with PIV > 500.2 exhibited a 13.737-fold increase (95% confidence interval [CI]: 7.260-25.994) in infectious complications compared to those with PIV ≤ 500.2, making PIV the strongest predictor. The most significant factors in differentiating between the groups were, in order of importance, Charlson comorbidity index, stone volume, preoperative serum creatinine level, and preoperative double-J stent placement. These factors were analyzed using multivariate logistic regression alongside PIV and SII, and two models were constructed. The predictive power of Model 1 was determined as Cox & Snell R² = 0.269 and Nagelkerke R² = 0.661, while Model 2 had a Cox & Snell R² value of 0.264 and a Nagelkerke R² value of 0.648.</p><p><strong>Conclusion: </strong>PIV and SII, derived from hemogram parameters, serve as predictive inflammatory indices for postoperative infectious complications. They provide valuable preoperative insight into the patient's immune and systemic inflammatory responses. When combined with other risk factors, these indices allow for the prediction of postoperative infectious complications.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"168"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical experience and outcomes of post chemotherapy midline extraperitoneal approach to retroperitoneal lymph node dissection.","authors":"Basil Razi, James Kovacic, Ankur Dhar, Andrew Shepherd, Venu Chalasani, Matthew Winter","doi":"10.1186/s12894-025-01853-0","DOIUrl":"10.1186/s12894-025-01853-0","url":null,"abstract":"<p><strong>Background: </strong>To detail the outcomes of an open midline extraperitoneal (midline EP) approach to post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) for metastatic testicular cancer.</p><p><strong>Methods: </strong>We analysed our prospectively maintained operative database from April 2020 to February 2023 for cases of midline EP approach to PC-RPLND, identifying a total of 11 patients across two hospitals in Sydney, Australia. Demographic and perioperative data was obtained from electronic medical records, including preoperative factors such as cancer staging and preoperative treatment.</p><p><strong>Results: </strong>Eleven patients were included in this study. The median age was 37 years with a median ASA grade of 3. There were a total of six left-sided and five right-sided cases. A modified template was used in eight cases, and a bilateral template was used in three. Tumour staging ranged from Stage IIA- IIIB, with a median maximal retroperitoneal tumour size post chemotherapy of 4.2 cm. Preoperative histology identified 4 cases of seminoma and 7 cases of nonseminomatous germ cell tumours (NSGCT). The median length of the procedure was 300 min, blood loss was 300mL, length of stay was 5 days, and post-operative days until bowel opening was 2 days. The median lymph node yield was 18, with active malignancy identified in five cases. There were four early complications and no late complications. 91% of the patients had preserved ejaculatory function.</p><p><strong>Conclusions: </strong>The open midline EP approach to PC-RPLND has demonstrated acceptable perioperative outcomes compared to other open surgical approaches, enabling surgeons to complete complex cases. Therefore, the midline EP approach should be considered when performing PC-RPLND.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"171"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive and continuous nursing strategies in perioperative management of upper urinary tract stones treated with holmium laser lithotripsy.","authors":"Ying Qiu, Weiying Huang, Li Ouyang","doi":"10.1186/s12894-025-01850-3","DOIUrl":"10.1186/s12894-025-01850-3","url":null,"abstract":"<p><strong>Objective: </strong>This research aims to analyze the effects of total, continuous nursing interventions as a perioperative care system for patients undergoing percutaneous nephrolithotripsy (PCNL) with upper urinary tract stones on postoperative: inflammatory response, oxidative stress, and stress hormones.</p><p><strong>Methods: </strong>In the study, 150 patients with upper urinary tract stones (renal and proximal upper urinary tract stones) underwent PCNL from January 2023 to December 2024. The patients were then randomly assigned into two groups; the control group (75 patients) received conventional nursing care interventions, and the study group (75 patients) received comprehensive and continuous nursing interventions. Postoperative levels of inflammatory markers (CRP, IL-10), oxidative stress indicators (MDA, SOD), and stress hormones (COR, ACTH, NE) were compared between the two groups. Additionally, the incidence of postoperative complications and length of hospital stay were recorded.</p><p><strong>Results: </strong>The study group exhibited significantly lower levels of postoperative inflammatory markers compared to the control group (p < 0.05). Improvements in oxidative stress indicators were notable, with a significant reduction in MDA levels and a marked increase in SOD levels (p < 0.05). Furthermore, stress hormone levels (COR, ACTH, NE) in the study group were significantly lower than those in the control group (p < 0.05). The incidence of postoperative complications in the study group (5.56%) was significantly lower than that in the control group (20.83%), with a reduced length of hospital stay and increased patient satisfaction (p < 0.05).</p><p><strong>Conclusion: </strong>The collaborative and continuous nursing strategy almost completely avoids postoperative inflammatory responses, reduces oxidative stress, and regulates the secretion of stress-related hormones, greatly improving recovery outcomes for upper urinary tract stone patients undergoing PCNL.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"170"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microwave ablation versus combined microwave ablation and transarterial chemoembolization for T1a renal cell carcinoma: a Single-Center retrospective study.","authors":"Çağrı Erdim, Sıla Solak, Mehmet Hamza Türkcanoğlu, Mustafa Fatih Arslan, Özgür Kılıçkesmez","doi":"10.1186/s12894-025-01858-9","DOIUrl":"10.1186/s12894-025-01858-9","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"167"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic high-flow priapism: a case of bilateral cavernous pseudoaneurysm irrigated by the right internal pudendal artery.","authors":"Yuhong Fan, Xinyan Zhao, Jingqin Fang, Dong Han, Jiayin Hu","doi":"10.1186/s12894-025-01860-1","DOIUrl":"10.1186/s12894-025-01860-1","url":null,"abstract":"<p><strong>Background: </strong>High-flow priapism is uncommon, and its association with bilateral cavernous pseudoaneurysms has seldom been reported.</p><p><strong>Case description: </strong>This paper presents an exceedingly rare case of high-flow priapism resulting from bilateral cavernous pseudoaneurysms that developed following a straddle injury. The diagnosis was established through blood gas analysis of cavernosal aspirate, ultrasound, and magnetic resonance imaging (MRI). Digital subtraction angiography (DSA) revealed that both cavernous pseudoaneurysms were irrigated by the right internal pudendal artery. Following three months of conservative treatment, the priapism resolved; however, voluntary erectile function was not restored.</p><p><strong>Conclusions: </strong>To the best of our knowledge, there have been no reported cases of bilateral cavernous pseudoaneurysms irrigated by the same side of internal pudendal artery. Through this case presentation, we aim to draw clinicians' attention to this unique presentation of bilateral cavernous pseudoaneurysms perfused by a single internal pudendal artery and its potential implications for treatment approach and prognosis.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"165"},"PeriodicalIF":1.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ureteral endometriosis post-hysterectomy for adenomyosis: a case report and literature review.","authors":"Yujuan Lu, Yu Wang","doi":"10.1186/s12894-025-01866-9","DOIUrl":"10.1186/s12894-025-01866-9","url":null,"abstract":"<p><strong>Objective: </strong>To explore the necessity of long-term pharmacological management following total hysterectomy for adenomyosis.</p><p><strong>Methods: </strong>A case of ureteral endometriosis identified over one year after laparoscopic total hysterectomy and bilateral salpingectomy for adenomyosis was retrospectively analyzed. Clinical data were reviewed, and related literature was summarized for discussion.</p><p><strong>Results: </strong>The patient underwent laparoscopic total hysterectomy and bilateral salpingectomy at our hospital more than one year prior because of adenomyosis. No pharmacological treatment was provided postsurgery. One year later, the patient presented with right lumbar discomfort. Imaging revealed hydronephrosis of the right kidney and dilation of the right ureter, leading to a diagnosis of right ureteral endometriosis. Laparoscopic excision of the ureteral endometriotic lesion was performed. Pathology confirmed right ureteral endometriosis with glandular cystic expansion. Postsurgery, the patient was treated with gonadotropin-releasing hormone agonist (GnRH-a) therapy (3.6 mg of goserelin via subcutaneous injection every 28 days for a total of six cycles). Treatment is ongoing. Follow-up ultrasound revealed no abnormalities in the kidneys or ureters, and no recurrence was observed during the five months of follow-up.</p><p><strong>Conclusion: </strong>Adenomyosis is often associated with deep endometriosis. Even if no evident deep pelvic endometriosis is identified during total hysterectomy, long-term pharmacological management postsurgery may still be necessary. This approach can reduce the incidence of deep endometriosis in organs such as the bladder, ureters, and intestines.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"164"},"PeriodicalIF":1.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative CRP is a predictive factor for prolonged hospital stay after radical cystectomy for bladder cancer.","authors":"Takuji Hayashi, Atsunari Kawashima, Takeshi Ujike, Tetsuya Takao, Mototaka Sato, Koji Yazawa, Hiromu Horitani, Hitoshi Takayama, Hiromu Noi, Kensaku Nishimura, Hidefumi Kishikawa, Makoto Matsushita, Kenichi Kakimoto, Akira Nagahara, Yu Iashizuya, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Norio Nonomura","doi":"10.1186/s12894-025-01847-y","DOIUrl":"10.1186/s12894-025-01847-y","url":null,"abstract":"<p><strong>Purpose: </strong>Radical cystectomy (RC) is a curative treatment for localized bladder cancer. We retrospectively investigated the predictive factors for prolonged hospital stay after RC, including patient characteristics, preoperative laboratory data, surgery-related factors, and postoperative complications.</p><p><strong>Methods: </strong>We retrospectively analyzed data from 1,257 bladder cancer patients who underwent RC between 2010 and 2024: 516 open RC (ORC), 206 laparoscopic RC (LRC), and 535 robot-assisted RC (RARC). The cumulative rate of postoperative discharge (living) was calculated based on postoperative hospital stay using the Kaplan-Meier method. Multivariate analyses of factors associated with postoperative hospital stay were performed using Cox regression analysis.</p><p><strong>Results: </strong>The median age of the cohort was 72.8 years, with 954 patients (75.9%) being male. The median preoperative C-reactive protein (CRP) level was 0.16 mg/dL (range, 0.0-28.3), and 196 patients (15.6%) had a CRP level ≥ 1.0 mg/dL. Multivariate analysis revealed that surgical procedure (RARC vs. ORC, p < 0.001; RARC vs. LRC, p < 0.001), urinary diversion type (ileal conduit vs. neobladder, p = 0.029), and preoperative CRP level (< 1.0 vs. ≥ 1.0 mg/dL, p < 0.001) were significantly associated with postoperative hospital stay. Notably, a preoperative CRP level ≥ 1.0 mg/dL remained significantly associated with postoperative hospital stay, even after adjusting for the surgical period and postoperative complications.</p><p><strong>Conclusion: </strong>A preoperative CRP level ≥ 1.0 mg/dL was an independent predictive factor for prolonged hospital stay after RC for bladder cancer, irrespective of the surgical period, surgical procedures, and postoperative complications.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"162"},"PeriodicalIF":1.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous nephroscopy combined with flexible ureteroscopy for treating calyceal outlet occlusion after partial nephrectomy: a case report.","authors":"Haiwen Huang, Yunfei Fan, Gang Zhang, Jianxing Li","doi":"10.1186/s12894-025-01864-x","DOIUrl":"10.1186/s12894-025-01864-x","url":null,"abstract":"<p><p>Tumors located near the renal collecting system often led to collecting system injuries during partial nephrectomy, with urinary leakage caused by collecting system rupture being a common complication. We report a rare case of another type of collecting system injury: intraoperative suturing caused occlusion of the upper calyceal outlet of the right kidney, resulting in hydronephrosis of the upper calyx and persistent urinary leakage postoperatively. Using a combination of percutaneous nephroscopic and ureteroscopic approaches, we located the occluded calyceal outlet and successfully restored urine drainage from the obstructed calyx by performing laser incision and balloon dilation to open and enlarge the calyceal outlet. Our case demonstrates that for iatrogenic occlusion of renal calyceal outlets caused by partial nephrectomy, combining percutaneous nephroscopic and ureteroscopic endoscopic surgery can effectively resolve calyceal obstruction.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"163"},"PeriodicalIF":1.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the changes in hydrogel spacer volume in patients treated with proton therapy for prostate cancer.","authors":"Kuniaki Inoue, Masatake Shinohara, Toshihisa Saka, Yoshihiko Hirao, Yasuhiro Shinohara, Tatsuyuki Higashikawa, Michinori Yamamoto","doi":"10.1186/s12894-025-01845-0","DOIUrl":"10.1186/s12894-025-01845-0","url":null,"abstract":"<p><strong>Background: </strong>Rectal bleeding is a recognized late complication of radiation therapy in the treatment of prostate cancer, and hydrogel spacers have been used to prevent this adverse effect. Previous reports have indicated that the volume of hydrogel spacers remains stable for at least 3 months after implantation [1]; however, no cases of early resolution have been reported. Therefore, this study aimed to investigate the hydrogel spacer volume changes over time.</p><p><strong>Methods: </strong>We included 103 patients implanted with hydrogel spacers who underwent proton therapy at our hospital between April 2020 and November 2022. Two patients were excluded due to improper hydrogel spacer placement beyond the prostatic side of Denonvilliers' fascia. To examine the volume of Space OAR, we measured the spacer volume using magnetic resonance imaging at the time of dosimetry treatment planning and again at 7 and 21 fractions in the remaining 101 patients.</p><p><strong>Results: </strong>Among the 101 patients, four exhibited a significant reduction in spacer volume at 21 fractions, and one of these patients experienced rectal bleeding.</p><p><strong>Conclusion: </strong>Unexpected early changes in the hydrogel spacer volume may increase rectal exposure from the time of radiation planning.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"160"},"PeriodicalIF":1.7,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}