BMC Urology最新文献

{"title":"Correction: Evaluation of the changes in hydrogel spacer volume in patients treated with proton therapy for prostate cancer.","authors":"Kuniaki Inoue, Masatake Shinohara, Toshihisa Saka, Yoshihiko Hirao, Yasuhiro Shinohara, Tatsuyuki Higashikawa, Michinori Yamamoto","doi":"10.1186/s12894-025-01942-0","DOIUrl":"10.1186/s12894-025-01942-0","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"228"},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The outcome of stenting and its duration after pyeloplasty in children with ureteropelvic junction obstruction (UPJO): a systematic review and meta-analysis.","authors":"Made Kresna Yudhistira Wiratma, Tanaya Ghinorawa, Prahara Yuri","doi":"10.1186/s12894-025-01841-4","DOIUrl":"10.1186/s12894-025-01841-4","url":null,"abstract":"<p><strong>Background: </strong>The complication related to the use of stent and its duration are still considered in the treatment option of UPJO despite the high success rates of several pyeloplasty techniques.</p><p><strong>Methods: </strong>A systematic search was performed using PubMed/MEDLINE, ScienceDirect, and Cochrane databases, selecting cohort and controlled trial studies until April 2023. The following medical subject headings (MeSH) were included in the search: stent, ureteropelvic junction obstruction, pyeloplasty and children. Complication and success rate related to the stent placement after pyeloplasty were recorded.</p><p><strong>Results: </strong>Eleven studies including 1072 patients were included. Eight studies compared stented versus non-stented pyeloplasty. Three studies compared 4-week stenting vs ≤ 2-week stenting. The total complication risk is decreased in stented group compared to non-stented group (OR 0.81, 95% CI 0.59-1.13). According to subgroup analysis, urinary leakage (OR 0.21 95% CI 0.10-0.47) and obstruction (OR 0.69 95% CI 0.32-1.47) are decreased in stented group. The total risk of complication is increased in 4-week stenting period (OR 5.11, 95% CI 2.43- 10.74) compared to ≤ 2-week stenting period, with the OR of each subgroup analysis is 4.64, 95% CI 1.8-11.97; 4.36, 95% CI 0.5-38.3 and 6.78, 95% CI 1.65-27.92 for fever, stent migration, and irritative symptom, respectively. There were no differences of success rate among the groups (OR 0.48, 95% CI 0.04-5.62).</p><p><strong>Conclusion: </strong>The use of stent can reduce the risk of urinary leakage after pyeloplasty in children. Stenting duration ≤ 2 weeks carries a smaller risk of complications with the same post operative success rate as stents with a longer duration.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"227"},"PeriodicalIF":1.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of flexible and navigable suction ureteral access sheath combined with single-use flexible ureteroscopes and percutaneous nephrolithotomy in the treatment of kidney stones > 2.5 cm: a single-center retrospective study.","authors":"Guoqing Liu, Xin Zhang, Zhaorong Xu, Xiao Li","doi":"10.1186/s12894-025-01930-4","DOIUrl":"10.1186/s12894-025-01930-4","url":null,"abstract":"<p><strong>Background and objective: </strong>When performing retrograde intrarenal surgery (RIRS), compared with conventional ureteral access sheaths (UAS), flexible and navigable suction ureteral access sheaths (FANs) can reduce the number of lithotripsy sessions and increase the stone-free rate (SFR). They have been widely applied in flexible ureteroscopic lithotripsy (FURL). Currently, ureteroscopic flexible ureteroscopes equipped with FANs are also showing remarkable outcomes in the treatment of large kidney stones. Therefore, the objective of this study was to explore the efficacy of single-use flexible ureteroscopes (su-fURS) combined with FANs in the treatment of kidney stones larger than 2.5 cm and to compare it with percutaneous nephrolithotomy (PCNL).</p><p><strong>Methods: </strong>Data of patients who underwent treatment of 2.5-3.8 cm kidney stones in the First Affiliated Hospital of Shandong Second Medical University from January 2024 to December 2024 were included in the study. According to the different surgical methods, they were divided into PCNL group and FANs group. The general data, intraoperative and postoperative related data of the patients in the two groups were collected and compared, where P < 0.05 represents statistical significance.</p><p><strong>Results: </strong>A total of 76 patients (41 PCNL, 35 FANs) were included in this study, and both groups achieved a very favorable SFR (85%, 93% vs. 80%, 91% P = 0.536, 0.840), and the difference was not statistically significant. The PCNL group had a shorter mean operative time (99.39 vs. 135.49 min P < 0.001) and a lower mean hospitalization cost (22, 865.60 vs. 26,031.91 ¥ P < 0.001). The FANs had a lower level of postoperative hemoglobin (Hb) drop (6.31 vs. 11.05 g/L P = 0.010) and a less severe level of postoperative pain (1.97 vs. 3.41 points P < 0.001), faster postoperative recovery (3.29 vs. 6.54d P < 0.001).</p><p><strong>Conclusions: </strong>FANs combined with su-FURS for the treatment of kidney stones larger than 2.5 cm have a high SFR, with less pain and quicker recovery for patients, making it a method worth promoting and applying in the clinic.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"226"},"PeriodicalIF":1.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined robot-assisted surgery of upper and lower genitourinary tract with excellent early functional and oncological outcome - a case report of a concomitant nerve-sparing radical prostatectomy, diverticulectomy and ureterectomy.","authors":"Jan Lüdecke, Mirjam Naomi Mohr, Till Rasmus Schneider, Joost Wilhelm Voß, Arne Strauß, Lutz Trojan, Mathias Reichert","doi":"10.1186/s12894-025-01901-9","DOIUrl":"10.1186/s12894-025-01901-9","url":null,"abstract":"<p><p>INTRODUCTION AND IMPORTANCE: \"Congenital anomalies of the kidney and urinary tract\" (CAKUT) represent a heterogeneous and rare group of disorders affecting the urinary tract. Despite the widespread availability of ultrasound, the diagnosis of congenital urinary tract malformations is often made in adulthood. As a result, CAKUT are typically incidental findings during imaging investigations. This case report represents the first description of a simultaneous surgical therapy of CAKUT and nerve-sparing-prostatectomy, demonstrating that concomitant surgery does not present disadvantages and that a successful nerve-sparing radical prostatectomy can still be performed under NeuroSAFE control. CASE PRESENTATION: In this report, we describe a patient with prostate adenocarcinoma who had an incidental finding of left-sided CAKUT, including kidney aplasia, ureterocele, and bladder diverticulum. The patient underwent a simultaneous nerve-sparing radical prostatectomy, ureterectomy, and diverticulectomy. After catheter removal on day 10 after surgery, the patient demonstrated adequate continence (6gr in 24 h pad test, 450 ml voiding volume, no residual urine). The pathological examination revealed a pT2c pN0 (0/5) R0, GS 3 + 4 = 7a adenocarcinoma of the prostate. The patient expressed high satisfaction with the surgery and its outcomes. CONCLUSION: This case demonstrates for the first time that a combined approach to complex surgeries of both the upper and lower genitourinary tracts, addressing oncological considerations, can be performed safely without compromising early functional or early oncological outcomes.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"225"},"PeriodicalIF":1.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel protocol for the characterization of ureteral stent echogenicity.","authors":"Clifford Jiajun He, Tyler Sheetz, Jonathan Katz, Vivek Pendem, Kevin Ho, Nicholas Trujillo, Sujit Tunuguntla, Robert Sah, Seth K Bechis, Roger L Sur, Manoj Monga","doi":"10.1186/s12894-025-01931-3","DOIUrl":"10.1186/s12894-025-01931-3","url":null,"abstract":"<p><strong>Background: </strong>Decreasing radiation exposure in renal colic management involves revisiting diagnostic, intraoperative, and postoperative practices. One approach is a shift in procedural standards from intraoperative fluoroscopy to ultrasonography. Despite the increased implementation of ultrasound in urology, the ultrasound visibility or echogenicity of various stents is not well-studied. Silicone stents, traditionally considered less radiopaque, pose challenges during placement under fluoroscopy due to their reduced visibility. However, a shift to ultrasound-based guidance can levels the playing field, as silicone stents demonstrate comparable echogenicity to stents made from other materials. This study aims to evaluate and quantify the echogenicity of different ureteral stents on the market, with a focus on silicone stents, which traditionally have been considered less radiopaque yet potentially advantageous for less patient discomfort.</p><p><strong>Methods: </strong>We conducted a simulation study using five different brands of ureteral stents in an ex-vivo porcine bladder model. We measured the mean grey intensity to quantify echogenicity of each stent. After comparing the echogenicity of individual stents, we grouped stents based on materials and diameters and performed T-tests.</p><p><strong>Results: </strong>We established that ureteral stents can demonstrate good visibility inside porcine bladder under ultrasound. Upon further investigation, we found that diameter is the most important variable in determining the measured echogenicity of ureteral stents. 8 Fr ureteral stents have higher measured echogenicity than the Sensor wire and 6 Fr stents. Stent materials also play a role in the measured echogenicity of ureteral stents. With the same diameter, silicone is measurably more echogenic than polyurethane.</p><p><strong>Conclusion: </strong>This study describes a novel quantitative assessment of ureteral stent echogenicity, which can guide the development of novel echogenic stents and provide a benchmark for existing stents. In addition, it suggests that ultrasonography may facilitate the placement of silicone stents, which historically have been more difficult to visualize with fluoroscopy.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"223"},"PeriodicalIF":1.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic floor rehabilitation before radical prostatectomy: a systematic review.","authors":"Oscar Aguila-Gimeno, Alba Jareño-Vicens, Clàudia Triñaque Recasens","doi":"10.1186/s12894-025-01932-2","DOIUrl":"10.1186/s12894-025-01932-2","url":null,"abstract":"<p><strong>Objective: </strong>To review the effectiveness of pelvic floor muscle strengthening before radical prostatectomy.</p><p><strong>Methodology: </strong>A search of publications was conducted in the following databases: PubMed, Scopus, Cochrane and Enfispo for articles published from 2019 to September 2024. A total of 199 articles were reviewed, of which 6 were selected and peer-reviewed using the CASPe questionnaire to assess methodological quality, resulting in the inclusion of 5 studies with a total of 642 participants.</p><p><strong>Results: </strong>Pelvic floor prehabilitation in patients undergoing radical prostatectomy aims to improve urinary continence, sexual function and quality of life. The studies analyzed show significant methodological variability, adding difficulty in comparing the results. Treatments that combine pelvic floor exercises with aerobic and resistance training show better functional recovery and continence outcomes. Less intensive programs do not show significant differences between groups. Studies with longer durations demonstrate clearer benefits, while shorter follow-up periods limit the evaluation of long-term efficacy. Additionally, few studies address erectile dysfunction, despite its impact on quality of life.</p><p><strong>Conclusion: </strong>Pelvic floor prehabilitation may help improve urinary continence following radical prostatectomy; however, there is a paucity of studies evaluating its application prior to surgery, and considerable variability exists in treatment protocols. No standardized clinical protocol exists, which hinders result comparisons. Although prehabilitation shows promising potential, current studies present heterogeneous results. Clinical trials are needed to standardize interventions, expand sample sizes, and conduct long-term follow-ups to consolidate evidence and improve patient care.</p><p><strong>Prospero register: </strong>Prospero Register: CRD42024619694.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"224"},"PeriodicalIF":1.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12403351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stem cell therapy for erectile dysfunction: promise or reality? - a systematic review and meta-analysis of clinical trials.","authors":"Samet Senel, Ahmet Halil Sevinc, Huseyin Gultekin, Abduvaliyev Jaxongir Ravshanbekovich, Huseyin Besiroglu, Murat Dursun, Ates Kadioglu","doi":"10.1186/s12894-025-01913-5","DOIUrl":"https://doi.org/10.1186/s12894-025-01913-5","url":null,"abstract":"<p><strong>Background: </strong>The outcomes of clinical trials on stem cell therapy (SCT) on erectile dysfunction (ED) treatment are promising but there is still no conclusive evidence regarding its efficacy. The aim of this meta-analysis is to compile studies that assess the effectiveness of SCT on ED to reach a more reliable conclusion.</p><p><strong>Methods: </strong>The meta-analysis was registered to PROSPERO (CRD42024540511). We utilized the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline to report the outcomes. Articles published from January 2000 to May 2024 were included for systematic review. We performed a systematic search using keywords: \"stem cell\" AND (\"erectile dysfunction\" OR \"erectile function\" OR \"erection\" OR \"impotence\").</p><p><strong>Results: </strong>We initially identified 2,013 studies in full publications or abstracts using the search terms. Eleven studies were included in systematic review and six of them were included in meta-analysis. Most studies included in systematic review reported improvements in erectile function following intracavernosal SCT. The meta-analysis revealed significant improvements at six months in international index of erectile function-5 (IIEF-5), international index of erectile function-erectile function domain) IIEF-EF, erectile hardness score (EHS), and peak systolic velocity (PSV) (p < 0.05). End-diastolic velocity (EDV) increased significantly at 3 months (p = 0.031) but not at six months (p = 0.868). Heterogeneity ranged from low to high (I² = 0-71.2%). No significant publication bias was detected (Egger's test p > 0.05).</p><p><strong>Conclusion: </strong>Intracavernosal SCT may increase scores on the questionnaires evaluated compared to baseline at six months which currently represent the longest reported follow-up duration but comparative trials with longer follow-up periods are needed to draw more definitive conclusions and reveal long-term effect.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"222"},"PeriodicalIF":1.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inflammation-based prognostic markers in renal cell carcinoma: insights from a 15-year experience.","authors":"Volkan Sen, Muhammed Selcuk Ozer, Alper Ege Sarıkaya, Bora Irer, Ozan Bozkurt","doi":"10.1186/s12894-025-01915-3","DOIUrl":"https://doi.org/10.1186/s12894-025-01915-3","url":null,"abstract":"<p><strong>Introduction: </strong>Renal cell carcinoma (RCC) represents nearly 90% of kidney cancers. With improvements in treatment and longer survival, reliable prognostic markers are increasingly important. This study investigated the prognostic value of systemic inflammatory markers and clinicopathological features in RCC patients undergoing nephrectomy.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed 418 patients who underwent radical or partial nephrectomy for RCC between 2009 and 2024. Preoperative hematologic markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), systemic inflammatory response index (SIRI), and systemic immune-inflammation index (SII), were evaluated. Their associations with overall survival (OS) and recurrence-free survival (RFS) were assessed using survival analyses and multivariate Cox regression.</p><p><strong>Results: </strong>The cohort had a median age of 60.5 years and a median follow-up of 72.3 months. Elevated NLR, PLR, SIRI, SII, and reduced LMR were associated with worse OS and RFS. On multivariate analysis, age > 64.5 years, higher tumor grade, NLR ≥ 2.93, and LMR < 3.67 independently predicted poorer OS.</p><p><strong>Conclusions: </strong>Simple, routinely available preoperative inflammatory markers, particularly NLR and LMR, may serve as useful predictors of survival in RCC patients.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"220"},"PeriodicalIF":1.9,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382283/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ipsilateral polyorchidism with cryptorchidism in a pediatric patient: a rare case report from a resource-limited setting.","authors":"Ashagre Gebremichael Ganta, Wintana Tesfaye Desta","doi":"10.1186/s12894-025-01916-2","DOIUrl":"https://doi.org/10.1186/s12894-025-01916-2","url":null,"abstract":"<p><strong>Background: </strong>Polyorchidism with cryptorchidism is an extremely rare congenital anomaly, particularly in children. Diagnosis and management are significantly more complex in low-middle-income countries (LMICs) due to resource limitations, including absent laparoscopy, increasing risks of torsion, malignancy, and infertility.</p><p><strong>Case presentation: </strong>An 8-year-old male from an LMIC presented with a non-palpable left testis. Preoperative ultrasonography detected an atrophic left intra-abdominal testis but missed a supernumerary testis. Mandatory open exploration (laparoscopy unavailable) revealed two left testes: one severely atrophic/hypoplastic (removed via orchiectomy) and a smaller viable cryptorchid testis (preserved via orchiopexy). Histopathology confirmed benign atrophy.</p><p><strong>Discussion: </strong>In LMICs, reliance on open surgery increases diagnostic/therapeutic challenges. Intraoperative discovery of the supernumerary testis underscores the need for meticulous surgical exploration despite inconclusive imaging. Orchiectomy of the atrophic testis highlights balancing endocrine preservation against malignancy risk. Embryologically, this may result from incomplete transverse division of the genital ridge or aberrant regression. Long-term endocrine follow-up and germinal surveillance are critical, especially amidst resource constraints.</p><p><strong>Conclusion: </strong>Managing concurrent polyorchidism and cryptorchidism in LMICs requires adapted strategies when advanced techniques are inaccessible. Open surgery remains vital diagnostically and therapeutically, necessitating vigilance for supernumerary testes. This case exemplifies balancing orchiectomy for non-viable tissue with orchiopexy for functional preservation, advocating context-sensitive surgical approaches in resource-limited pediatric urology.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"219"},"PeriodicalIF":1.9,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrograde intrarenal surgery with intelligent pressure control: experience from a primary hospital in China.","authors":"Xin Liu, Wangsheng Huo, Yanjun Wang, Hui Chai, Libin Chen, Hui Meng, Zhihong Gong, Hongze Zhang, Jian Lang, Zhantian An, Wei Wei","doi":"10.1186/s12894-025-01910-8","DOIUrl":"https://doi.org/10.1186/s12894-025-01910-8","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the clinical outcomes of conventional retrograde intrarenal surgery (RIRS) and RIRS with intelligent pressure control, as well as to identify factors influencing the stone-free rate (SFR).</p><p><strong>Materials and methods: </strong>We conducted a retrospective review of 101 patients treated with either conventional RIRS or RIRS with intelligent pressure control from September 2023 to September 2024. Clinical and stone-related parameters were collected for comparison between the two methods, and factors affecting SFR were examined using univariate and multivariate logistic regression analyses.</p><p><strong>Results: </strong>The SFR was significantly higher in the intelligent pressure control group compared to the conventional RIRS group (89.8% vs. 73.1%, p = 0.032). No statistically significant differences were found between the two groups regarding operative time or post-operative hospital stays. The incidence of post-operative fever was lower in the intelligent pressure control group than in the conventional RIRS group (2.0% vs. 9.8%), although this difference did not reach statistical significance (p = 0.205). Univariate analysis identified stone size, stone density, number, location, and surgical method as factors associated with SFR. Multivariate analysis further confirmed that stone size, density, and surgical method significantly impacted SFR.</p><p><strong>Conclusion: </strong>RIRS with intelligent pressure control significantly improves the stone-free rate compared to conventional RIRS, without increasing complications, hospitalization duration, or operative time. Additionally, stone size and density were influential factors for SFR.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"218"},"PeriodicalIF":1.9,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12379481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144943820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}