BMC Urology最新文献

{"title":"A case of artificial urinary sphincter implantation in a patient who underwent both urethroplasty and ileal neobladder construction.","authors":"Hibiki Hirose, Tadashi Tabei, Yushi Araki, Hideki Ouchi, Takuma Nirei, Kazuki Kobayashi","doi":"10.1186/s12894-025-01871-y","DOIUrl":"10.1186/s12894-025-01871-y","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"176"},"PeriodicalIF":1.7,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12273492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior conduit fixation with retroperitonealization of uretero-ileal anastomosis after open radical cystectomy reduces the postoperative complication rate: a retrospective, matched-paired single-center analysis.","authors":"Vukovic Marko, Kavaric Petar, Magdelinic Aleksandar, Albijanic Marko, Rebronja Almir, Sabovic Eldin","doi":"10.1186/s12894-025-01869-6","DOIUrl":"10.1186/s12894-025-01869-6","url":null,"abstract":"<p><strong>Background: </strong>Our study aimed to assess the efficacy of posterior conduit fixation with retroperitoneal ureteroileal anastomosis (UIA) in reducing perioperative complications after radical cystectomy (RC) with ileal conduit (IC) urinary diversion.</p><p><strong>Methods: </strong>We conducted a retrospective case-control study, including 150 patients who underwent either modified IC technique (extraperitonealized anastomosis with posterior conduit fixation; n = 79) or the conventional IC technique (n = 71). The primary endpoints were the incidence of clinical parastomal hernia (PSH) and ileus. Secondary endpoints included operative time, postoperative complication rates, and length of hospital stay (LOS). Multivariate logistic regression was performed to identify predictors of early and late stoma- related complications.</p><p><strong>Results: </strong>The modified group showed significantly lower incidence of both early and late postoperative complications, including ileus and PSH, compared to the conventional group (8.86% vs. 28.1%, p = 0.01 and 7.6% vs. 17%, p = 0.03, respectively) after a median follow-up of 34 months. Corresponding hazard ratios were 0.312 (95% CI: 0.047-0.798, p = 0.01) for early complications and 0.267 (95% CI: 0.105-0.611, p = 0.03) for late complications.</p><p><strong>Conclusion: </strong>The results support our hypothesis that extraperitoneal ureteroileal anastomosis combined with posterior conduit fixation effectively reduces the risk of both early and late postoperative complications, including parastomal hernia and ileus.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"173"},"PeriodicalIF":1.7,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic alterations of prostate cancer: in localized and metastatic prostate cancer.","authors":"Chang Eil Yoon, San Kang, Seung Ah Rhew, Hyeok Jae Kwon, Dongho Shin, Hyong Woo Moon, Mee Young Kim, Ji Youl Lee","doi":"10.1186/s12894-025-01840-5","DOIUrl":"10.1186/s12894-025-01840-5","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"166"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radical nephrectomy with inferior vena caval thrombectomy for level I to IV tumor thrombus: long-term single-center experience.","authors":"Pavel Navratil, Jiri Chalupnik, Miroslav Louda, Petr Habal, Pavel Zacek, Milos Brodak, Jaroslav Pacovsky","doi":"10.1186/s12894-025-01854-z","DOIUrl":"10.1186/s12894-025-01854-z","url":null,"abstract":"<p><strong>Background: </strong>Renal cell carcinoma (RCC) is a prevalent kidney malignancy known for its aggressive nature and potential to extend into the renal vein or inferior vena cava (IVC), affecting patient prognosis and treatment strategies.</p><p><strong>Objective: </strong>To assess the long-term outcomes and effectiveness of radical nephrectomy with IVC thrombectomy in patients with RCC presenting with level I-IV IVC thrombus.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 164 adult patients treated for RCC with IVC thrombectomy at a tertiary care center from January 2004 to December 2023. Data including demographics, clinical characteristics, tumor specifics, surgical details, complications, and survival rates were meticulously reviewed.</p><p><strong>Results: </strong>Among the patients, the mean age was 63.7 years, predominantly male (69.5%). The histological profile showed a majority of clear cell carcinoma (95.7%), with most tumors located on the right side (71.3%). Thrombus levels were distributed across I-IV, with 41 (25%) patients presenting with level I, 33 (20.1%) with level II, 55 (33.5%) with level III, and 35 (21.4%) with level IV thrombi. The mean operation time and blood loss increased with thrombus level. Perioperative complications were recorded in 57.3% of patients, and over half of the patients experienced disease recurrence (54.9%). The overall 5-year survival rate stood at 42.1%, with notably better survival in patients with level I thrombi.</p><p><strong>Conclusion: </strong>Radical nephrectomy with IVC thrombectomy provides a potential for long-term control in patients with RCC and IVC thrombus, although it is associated with significant morbidity. Multidisciplinary care and expert surgical intervention are crucial for improving patient outcomes. The variability in survival rates across thrombus levels underscores the need for individualized treatment approaches.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"169"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effectiveness of single-dose levofloxacin with single-dose fosfomycin pre-urodynamic study related to the incidence of urinary tract infection: a randomized controlled trial.","authors":"Harrina Erlianti Rahardjo, Fina Widia, Cindy Wijaya, Kevin Leonardo, Alfred Tanjung, Muhammad Hanif Arfiananda, Fatimah Nuwwaaridya Fitriani, Rahmat Aidil Fajar Siregar, Andika Afriansyah","doi":"10.1186/s12894-025-01839-y","DOIUrl":"10.1186/s12894-025-01839-y","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"172"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of Pan-Immune inflammation value and systemic Immune-Inflammation index as potential biomarkers in predicting infectious complications following retrograde intrarenal surgery.","authors":"Bedreddin Kalyenci, Ferhat Çoban, Hasan Sulhan, Mehmet Özgür Yücel, Can Benlioğlu, Gazi Kaz, Tayfun Şahinkanat, Ali Çift","doi":"10.1186/s12894-025-01859-8","DOIUrl":"10.1186/s12894-025-01859-8","url":null,"abstract":"<p><strong>Background: </strong>To predict postoperative infectious complications by utilizing hemogram parameters and derived inflammation indices and to analyze patient-related risk factors to propose a nomogram.</p><p><strong>Methods: </strong>The data of patients who underwent retrograde intrarenal surgery were reviewed. The patients were categorized into two groups: those without infectious complications (Group A) and those with infectious complications (Group B). Infectious complications were defined as fever persisting above 38 °C for 48 h and the presence of two or more systemic inflammatory response syndrome (SIRS) criteria. Hemogram parameters and inflammation indices were examined to predict infectious complications. The study utilized neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR), along with the pan-immune-inflammation value (PIV) and systemic immune-inflammation index (SII).</p><p><strong>Results: </strong>The data of 658 cases were evaluated. No infectious complications were observed in 610 cases (92.7%), while 33 cases (5.0%) developed fever, and 15 cases (2.3%) met the criteria for SIRS. The optimal cut-off values for distinguishing between groups were determined as follows: >2.66 for NLR, > 122.5 for PLR, < 2.81 for LMR, > 619.4 for SII, and > 500.2 for PIV. Patients with PIV > 500.2 exhibited a 13.737-fold increase (95% confidence interval [CI]: 7.260-25.994) in infectious complications compared to those with PIV ≤ 500.2, making PIV the strongest predictor. The most significant factors in differentiating between the groups were, in order of importance, Charlson comorbidity index, stone volume, preoperative serum creatinine level, and preoperative double-J stent placement. These factors were analyzed using multivariate logistic regression alongside PIV and SII, and two models were constructed. The predictive power of Model 1 was determined as Cox & Snell R² = 0.269 and Nagelkerke R² = 0.661, while Model 2 had a Cox & Snell R² value of 0.264 and a Nagelkerke R² value of 0.648.</p><p><strong>Conclusion: </strong>PIV and SII, derived from hemogram parameters, serve as predictive inflammatory indices for postoperative infectious complications. They provide valuable preoperative insight into the patient's immune and systemic inflammatory responses. When combined with other risk factors, these indices allow for the prediction of postoperative infectious complications.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"168"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical experience and outcomes of post chemotherapy midline extraperitoneal approach to retroperitoneal lymph node dissection.","authors":"Basil Razi, James Kovacic, Ankur Dhar, Andrew Shepherd, Venu Chalasani, Matthew Winter","doi":"10.1186/s12894-025-01853-0","DOIUrl":"10.1186/s12894-025-01853-0","url":null,"abstract":"<p><strong>Background: </strong>To detail the outcomes of an open midline extraperitoneal (midline EP) approach to post-chemotherapy retroperitoneal lymph node dissection (PC-RPLND) for metastatic testicular cancer.</p><p><strong>Methods: </strong>We analysed our prospectively maintained operative database from April 2020 to February 2023 for cases of midline EP approach to PC-RPLND, identifying a total of 11 patients across two hospitals in Sydney, Australia. Demographic and perioperative data was obtained from electronic medical records, including preoperative factors such as cancer staging and preoperative treatment.</p><p><strong>Results: </strong>Eleven patients were included in this study. The median age was 37 years with a median ASA grade of 3. There were a total of six left-sided and five right-sided cases. A modified template was used in eight cases, and a bilateral template was used in three. Tumour staging ranged from Stage IIA- IIIB, with a median maximal retroperitoneal tumour size post chemotherapy of 4.2 cm. Preoperative histology identified 4 cases of seminoma and 7 cases of nonseminomatous germ cell tumours (NSGCT). The median length of the procedure was 300 min, blood loss was 300mL, length of stay was 5 days, and post-operative days until bowel opening was 2 days. The median lymph node yield was 18, with active malignancy identified in five cases. There were four early complications and no late complications. 91% of the patients had preserved ejaculatory function.</p><p><strong>Conclusions: </strong>The open midline EP approach to PC-RPLND has demonstrated acceptable perioperative outcomes compared to other open surgical approaches, enabling surgeons to complete complex cases. Therefore, the midline EP approach should be considered when performing PC-RPLND.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"171"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive and continuous nursing strategies in perioperative management of upper urinary tract stones treated with holmium laser lithotripsy.","authors":"Ying Qiu, Weiying Huang, Li Ouyang","doi":"10.1186/s12894-025-01850-3","DOIUrl":"10.1186/s12894-025-01850-3","url":null,"abstract":"<p><strong>Objective: </strong>This research aims to analyze the effects of total, continuous nursing interventions as a perioperative care system for patients undergoing percutaneous nephrolithotripsy (PCNL) with upper urinary tract stones on postoperative: inflammatory response, oxidative stress, and stress hormones.</p><p><strong>Methods: </strong>In the study, 150 patients with upper urinary tract stones (renal and proximal upper urinary tract stones) underwent PCNL from January 2023 to December 2024. The patients were then randomly assigned into two groups; the control group (75 patients) received conventional nursing care interventions, and the study group (75 patients) received comprehensive and continuous nursing interventions. Postoperative levels of inflammatory markers (CRP, IL-10), oxidative stress indicators (MDA, SOD), and stress hormones (COR, ACTH, NE) were compared between the two groups. Additionally, the incidence of postoperative complications and length of hospital stay were recorded.</p><p><strong>Results: </strong>The study group exhibited significantly lower levels of postoperative inflammatory markers compared to the control group (p < 0.05). Improvements in oxidative stress indicators were notable, with a significant reduction in MDA levels and a marked increase in SOD levels (p < 0.05). Furthermore, stress hormone levels (COR, ACTH, NE) in the study group were significantly lower than those in the control group (p < 0.05). The incidence of postoperative complications in the study group (5.56%) was significantly lower than that in the control group (20.83%), with a reduced length of hospital stay and increased patient satisfaction (p < 0.05).</p><p><strong>Conclusion: </strong>The collaborative and continuous nursing strategy almost completely avoids postoperative inflammatory responses, reduces oxidative stress, and regulates the secretion of stress-related hormones, greatly improving recovery outcomes for upper urinary tract stone patients undergoing PCNL.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"170"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microwave ablation versus combined microwave ablation and transarterial chemoembolization for T1a renal cell carcinoma: a Single-Center retrospective study.","authors":"Çağrı Erdim, Sıla Solak, Mehmet Hamza Türkcanoğlu, Mustafa Fatih Arslan, Özgür Kılıçkesmez","doi":"10.1186/s12894-025-01858-9","DOIUrl":"10.1186/s12894-025-01858-9","url":null,"abstract":"","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"167"},"PeriodicalIF":1.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic high-flow priapism: a case of bilateral cavernous pseudoaneurysm irrigated by the right internal pudendal artery.","authors":"Yuhong Fan, Xinyan Zhao, Jingqin Fang, Dong Han, Jiayin Hu","doi":"10.1186/s12894-025-01860-1","DOIUrl":"10.1186/s12894-025-01860-1","url":null,"abstract":"<p><strong>Background: </strong>High-flow priapism is uncommon, and its association with bilateral cavernous pseudoaneurysms has seldom been reported.</p><p><strong>Case description: </strong>This paper presents an exceedingly rare case of high-flow priapism resulting from bilateral cavernous pseudoaneurysms that developed following a straddle injury. The diagnosis was established through blood gas analysis of cavernosal aspirate, ultrasound, and magnetic resonance imaging (MRI). Digital subtraction angiography (DSA) revealed that both cavernous pseudoaneurysms were irrigated by the right internal pudendal artery. Following three months of conservative treatment, the priapism resolved; however, voluntary erectile function was not restored.</p><p><strong>Conclusions: </strong>To the best of our knowledge, there have been no reported cases of bilateral cavernous pseudoaneurysms irrigated by the same side of internal pudendal artery. Through this case presentation, we aim to draw clinicians' attention to this unique presentation of bilateral cavernous pseudoaneurysms perfused by a single internal pudendal artery and its potential implications for treatment approach and prognosis.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"165"},"PeriodicalIF":1.7,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}