{"title":"Diagnostic performance of advanced large language models in cystoscopy: evidence from a retrospective study and clinical cases.","authors":"Linfa Guo, Yingtong Zuo, Zuhaer Yisha, Jiuling Liu, Aodun Gu, Refate Yushan, Guiyong Liu, Sheng Li, Tongzu Liu, Xiaolong Wang","doi":"10.1186/s12894-025-01740-8","DOIUrl":"https://doi.org/10.1186/s12894-025-01740-8","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic capabilities of advanced large language models (LLMs) in interpreting cystoscopy images for the identification of common urological conditions.</p><p><strong>Materials and methods: </strong>A retrospective analysis was conducted on 603 cystoscopy images obtained from 101 procedures. Two advanced LLMs, both at the forefront of artificial intelligence technology, were employed to interpret these images. The diagnostic interpretations generated by these LLMs were systematically compared against standard clinical diagnostic assessments. The study's primary outcome measure was the overall diagnostic accuracy of the LLMs. Secondary outcomes focused on evaluating condition-specific accuracies across various urological conditions.</p><p><strong>Results: </strong>The combined diagnostic accuracy of both LLMs was 89.2%, with ChatGPT-4 V and Claude 3.5 Sonnet achieving accuracies of 82.8% and 79.8%, respectively. Condition-specific accuracies varied considerably, for specific urological disorders: bladder tumors (ChatGPT-4 V: 92.2%, Claude 3.5 Sonnet: 80.9%), BPH (35.3%, 32.4%), cystitis (94.5%, 98.9%), bladder diverticula (92.3%, 53.8%), and bladder trabeculae (55.8%, 59.6%). As for normal anatomical structures: ureteral orifice (ChatGPT-4 V: 48.8%, Claude 3.5 Sonnet: 61.0%), bladder neck (97.9%, 93.8%), and prostatic urethra (64.3%,57.1%).</p><p><strong>Conclusions: </strong>Advanced language models demonstrated varying levels of diagnostic accuracy in cystoscopy image interpretation, excelling in cystitis detection while showing lower accuracy for other conditions, notably benign prostatic hyperplasia. These findings suggest promising potential for LLMs as supportive tools in urological diagnosis, particularly for urologists in training or early career stages. This study underscores the need for continued research and development to optimize these AI-driven tools, with the ultimate goal of improving diagnostic accuracy and efficiency in urological practice.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"64"},"PeriodicalIF":1.7,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC UrologyPub Date : 2025-03-28DOI: 10.1186/s12894-025-01755-1
Felix Grases, Antonia Costa-Bauzá, Francesca Julià, Bernat Isern, Jordi Guimerà, José Luis Bauzá-Quetglas, Valentí Tubau, Enrique Pieras
{"title":"Evidence of bacterial imprints in different types of non-struvite kidney stones.","authors":"Felix Grases, Antonia Costa-Bauzá, Francesca Julià, Bernat Isern, Jordi Guimerà, José Luis Bauzá-Quetglas, Valentí Tubau, Enrique Pieras","doi":"10.1186/s12894-025-01755-1","DOIUrl":"https://doi.org/10.1186/s12894-025-01755-1","url":null,"abstract":"<p><strong>Background: </strong>Recent studies of renal lithiasis identified bacterial imprints in apatite phosphate stones and mixed calcium oxalate/apatite phosphate stones, neither of which contained struvite.</p><p><strong>Methods: </strong>This cross-sectional observational study examined 903 stones that were collected from 844 patients during the course of 1 year. All stones were initially examined by stereoscopic microscopy. Stone fragments were then examined by scanning electron microscopy + microanalysis by X-ray dispersive energy and by Fourier-transform infrared spectroscopy. When bacterial imprints were detected, biochemical and bacteriological analysis of the patient's urine was performed.</p><p><strong>Results: </strong>We found 8 renal stones that had bacterial imprints but no struvite. All 8 stones contained hydroxyapatite, and the imprints were located in this region. Five stones contained hydroxyapatite as the major component, two stones were mixed hydroxyapatite/calcium oxalate dihydrate stones, one was a papillary calcium oxalate monohydrate stone in which bacterial imprints were located at Randall's plaque and the other was a cavity calcium oxalate monohydrate stone that contained hydroxyapatite in the central core with bacterial imprints.</p><p><strong>Conclusion: </strong>We identified bacterial imprints in different types of renal stones that lacked struvite, including papillary stones, and these imprints were always present in a hydroxyapatite matrix. Notably, a urinary pH above 6.0 favors the formation of apatite phosphates and the growth of bacteria. Our findings point to the importance of controlling urinary pH to prevent bacteria-mediated calculogenic processes.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"63"},"PeriodicalIF":1.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC UrologyPub Date : 2025-03-28DOI: 10.1186/s12894-025-01744-4
Jianda Dong, Lailai Fan, Qiaolin Wu, Zhouci Zheng
{"title":"Retinoid X receptor γ predicts the prognosis and is associated with immune infiltration in kidney renal clear cell carcinoma: a qRT-PCR, TCGA and in silico research.","authors":"Jianda Dong, Lailai Fan, Qiaolin Wu, Zhouci Zheng","doi":"10.1186/s12894-025-01744-4","DOIUrl":"https://doi.org/10.1186/s12894-025-01744-4","url":null,"abstract":"<p><strong>Background: </strong>Kidney clear cell carcinoma (KIRC) stands as one of the most prevalent primary malignant tumors, showcasing significant heterogeneity within the urological system. However, the precise molecular mechanisms underpinning tumorigenesis in KIRC remain elusive. While Retinoid X receptor γ (RXRG) has been implicated in various diseases and human cancers, its specific role in KIRC remains undetermined. This research aimed to investigate the involvement of RXRG in KIRC pathogenesis.</p><p><strong>Methods: </strong>Quantitative real-time polymerase chain reaction was performed to evaluate the expression levels of RXRG in KIRC. Utilizing RNA-seq data and corresponding clinicopathological information from The Cancer Genome Atlas (TCGA) database, we embarked on an analysis to ascertain the prognostic significance of RXRG in KIRC. Furthermore, bioinformatics analyses were employed to delineate the preliminary molecular mechanisms through which RXRG operates in KIRC tumorigenesis.</p><p><strong>Results: </strong>Our findings revealed a significant downregulation of RXRG in KIRC tumor tissues compared to normal kidney tissues, as evidenced in local and TCGA cohorts. Diminished RXRG expression correlated with adverse clinicopathological characteristics, including larger tumor size, higher clinical stage, and advanced histologic grade. Cox regression analyses unveiled that reduced RXRG expression was associated with poorer overall survival (OS) and disease-free survival (DFS) rates in KIRC patients. Bioinformatics analyses indicated that the RXRG-related differentially expressed genes (DEGs) were involved in tumorigenesis and metabolism by regulating a series of signaling pathways. Using ssGSEA, we found that RXRG expression was significantly associated with NK cells and macrophages.</p><p><strong>Conclusion: </strong>Our study provides new insights and evidence that RXRG is involved in the tumorigenesis of KIRC and may be a suitable target for immunotherapy in KIRC.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"62"},"PeriodicalIF":1.7,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC UrologyPub Date : 2025-03-27DOI: 10.1186/s12894-024-01648-9
Nilüfer Acar Tek, Tevfik Koçak, Süleyman Yeşil, Tevfik Sinan Sözen
{"title":"A novel equation synthesis for estimating resting energy expenditure in prostate cancer patients.","authors":"Nilüfer Acar Tek, Tevfik Koçak, Süleyman Yeşil, Tevfik Sinan Sözen","doi":"10.1186/s12894-024-01648-9","DOIUrl":"10.1186/s12894-024-01648-9","url":null,"abstract":"<p><strong>Background: </strong>An accurate calculation of energy expenditure (REE) is necessary for estimating energy needs in malign prostate cancer. The purpose of this research was to evaluate the accuracy of the established novel equation for predicting REE in malign and benign prostate patients versus the accuracy of the previously used predictive equations based on REE measured by indirect calorimetry.</p><p><strong>Methods: </strong>The study was conducted as a cross-sectional case-control study and between December 2020 and May 2021 with 40 individuals over the age of 40 who applied to the Urology Clinic of Gazi University Faculty of Medicine. Subjects with 41 malign prostate and 42 benign prostate patients were both over the age of 40 (65.3 ± 6.30 years) and recruited for the study. Cosmed-FitMate GS Indirect Calorimetry with Canopyhood (Rome, Italy) was used to measure REE. A full body composition analysis and anthropometric measurements were taken.</p><p><strong>Clinical trial number: </strong>Not applicable.</p><p><strong>Results: </strong>Malign prostate group PSA Total and measured REE values (4.93 ± 5.44 ng/ml, 1722.9 ± 272.69 kcal/d, respectively) were statistically significantly higher than benign group (1.76 ± 0.73 ng/ml, 1670.5 ± 266.76 kcal/d, respectively) (p = 0.022). Malign prostate group (MPG) and benign prostate group (BPG) have the highest percentage of the accurate prediction value of Eq. 80.9% (novel equation MPG) and 64.2% (novel equation BPG). The bias of the equations varied from - 36.5% (Barcellos II Equation) to 19.2% (Mifflin-St. Jeor equation) for the malign prostate group and varied from - 41.1% (Barcellos II Equation) to 17.7% (Mifflin-St. Jeor equation) in the benign prostate group. The smallest root mean squared error (RMSE) values in the malign and benign prostate groups were novel equation MPG (149 kcal/d) and novel equation BPG (202 kcal/d). The new specific equation for malign prostate cancer: REE = 3192,258+ (208,326* body weight (WT)) - (20,285* height (HT)) - (187,549* fat free mass (FFM)) - (203,214* fat mass (FM)) + (4,194* prostate specific antigen total (PSAT)). The new specific equation for the benign prostate group is REE = 615,922+ (13,094*WT). Bland-Altman plots reveal an equally random distribution of novel equations in the malign and benign prostate groups.</p><p><strong>Conclusions: </strong>Previously established prediction equations for REE may be inconsistent. Utilising the PSAT parameter, we formulated novel energy prediction equations specific to prostate cancer. In any case, the novel predictive equations enable clinicians to estimate REE in people with malign and benign prostate groups with sufficient and most acceptable accuracy.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"61"},"PeriodicalIF":1.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC UrologyPub Date : 2025-03-27DOI: 10.1186/s12894-025-01748-0
Samet Senel, Ilker Teke, Rifat Burak Ergul, Resat Aydin, Ahmet Halil Sevinc, Murat Dursun, Ates Kadioglu
{"title":"Long-term results of modified Nesbit corporoplasty with medial neurovascular bundle dissection approach for ventral congenital penile curvature from a high-volume center.","authors":"Samet Senel, Ilker Teke, Rifat Burak Ergul, Resat Aydin, Ahmet Halil Sevinc, Murat Dursun, Ates Kadioglu","doi":"10.1186/s12894-025-01748-0","DOIUrl":"10.1186/s12894-025-01748-0","url":null,"abstract":"<p><strong>Background: </strong>Modified Nesbit corporoplasty with medial or lateral neurovascular bundle (NVB) dissection approach is one of the surgical methods aiming to correct the deformity of congenital penile curvature (CPC). We aimed to present the postoperative outcome and complications of patients undergoing modified Nesbit corporoplasty with medial NVB dissection approach for ventral CPC.</p><p><strong>Methods: </strong>One hundred five patients who underwent modified Nesbit corporoplasty procedure with medial NVB dissection for ventral CPC between 2007 and 2024 were included in the study. Preoperative (age, curvature type and degree) and postoperative (follow-up period, anatomical success, penile length loss, curvature recurrence, bothersome bumps and/or knots, penile and/or glans sensory loss, de-novo erectile dysfunction) data of all patients were recorded.</p><p><strong>Results: </strong>The mean age of patients was 23.8 ± 5.2 years. The mean degree of curvature was 54.8 ± 13.1°. Median penile length loss was two (IQR:1-3) cm. Anatomical success was achieved in ninety-five (91.5%) patients. The mean postoperative follow up period was 9.8 ± 4.5 (IQR:45-60) years. Recurrence rate and presence of bothersome bumps and/or knots were 4.8% and 6.7%, respectively. None of the patients reported penile and/or glans sensory loss and four (3.8%) patients had de-novo erectile dysfunction during the follow-up period.</p><p><strong>Conclusion: </strong>The present study has a large series demonstrating that Modified Nesbit corporoplasty with medial dissection could be an alternative approach in correcting ventral CPC with high anatomic and functional success rate and low recurrence rate.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"60"},"PeriodicalIF":1.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948824/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of prostate volume on Retzius-sparing robot-assisted laparoscopic radical prostatectomy with retrograde release of the neurovascular bundle.","authors":"Yang Liu, Zihao Liu, Zhun Wang, Yuan Shao, Zhen Yang, Hua Huang, Zeyuan Wang, Zhinan Fu, Simeng Wen, Yuanjie Niu, Yong Wang","doi":"10.1186/s12894-025-01745-3","DOIUrl":"10.1186/s12894-025-01745-3","url":null,"abstract":"<p><strong>Objective: </strong>Robot-assisted radical prostatectomy (RARP) has emerged as a primary treatment modality for localized prostate cancer. In this context, we report a novel surgical technique termed Retzius-sparing robot-assisted laparoscopic radical prostatectomy with retrograde release of the neurovascular bundle (RNRS-RARP). This study aims to assess the perioperative, oncological, and functional outcomes of RNRS-RARP across varying prostate volumes.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on clinical data retrieved from 298 patients who underwent RNRS-RARP from October 2021 to September 2023. Patients were stratified into three groups based on pathological prostate weight: ≤ 30 g, 30-50 g, and ≥ 50 g. Comparative analyses were performed on perioperative and postoperative oncological and functional outcomes among the three groups to discern variations. Separate analyses were performed for patients who received neoadjuvant therapy and those who did not. Additionally, independent predictors of immediate continence following RNRS-RARP were investigated.</p><p><strong>Results: </strong>Patients with larger prostate volumes were significantly older and have higher body mass index and prostate-specific antigen (PSA) (all p < 0.05). Larger prostate volumes exhibited prolonged median console time (65 vs. 70 vs. 90 min, p < 0.01) and increased median estimated blood loss (95 vs. 90 vs. 100 ml). There were no significant differences in duration of catheterization, length of stay, postoperative complications, positive surgical margin, PSA recurrence after 6 months, 1 month and 3 months continence. Immediate continence worsened with increasing prostate volume (80.0% vs. 77.5% vs. 64.2%, p = 0.04). Prostate volume (OR = 0.98; 95% Cl: 0.97-0.99; p = 0.03), age (OR = 0.90; 95% Cl: 0.86-0.95; p < 0.01), and clinical T stage (OR = 0.31; 95% Cl: 0.13-0.74; p = 0.01) were independent risk factors for immediate continence, with an area under the curve of 0.75 in the predictive model.</p><p><strong>Conclusion: </strong>RNRS-RARP can be safely performed regardless of prostate volume. As prostate volume increases, both console time and estimated blood loss tend to rise. However, the oncological outcomes and complication rates remained similar. Immediate continence was significantly lower with larger prostate volume, which also emerged as an independent predictor.</p><p><strong>Clinical trial registration: </strong>The clinical trial registration number is ChiCTR2200066350 (December1, 2022).</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"59"},"PeriodicalIF":1.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Redo laparoscopic pyeloplasty for recurrent ureteropelvic junction obstruction: a single center experience and a review of the literature.","authors":"Dimitrios Diamantidis, Stavros Lailisidis, Nikolaos Panagiotopoulos, Stavros Giannopoulos, Chrysostomos Georgellis, Georgios Tsakaldimis, Christos Kalaitzis, Stilianos Giannakopoulos","doi":"10.1186/s12894-025-01746-2","DOIUrl":"10.1186/s12894-025-01746-2","url":null,"abstract":"<p><strong>Backround: </strong>To describe and analyze our experience with secondary (redo) laparoscopic pyeloplasty (rLP) in managing recurrent ureteropelvic junction obstruction (UPJO) following primary pyeloplasty, and to compare our outcomes with those reported in the existing literature.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients who underwent rLP for recurrent UPJO. Baseline characteristics, detailed histories of previous pyeloplasties, operative profiles, and follow-up data were collected and analyzed. Furthermore, a comprehensive literature review was performed using PubMed.</p><p><strong>Results: </strong>The study included eight patients (four men, four women) with a mean age of 27 years who underwent rLP. Among them, three had left-side and five had right-side involvement. Three patients had undergone open pyeloplasty, three laparoscopic pyeloplasty, one robot-assisted pyeloplasty, and one laparoscopic pyeloplasty and failed salvage endopyelotomy. Recurrent UPJO etiologies were recurrent stenosis (five cases), fibrosis and adhesions (two cases), and a combination of fibrosis, adhesions, and high insertion (one case). No crossing vessels were involved. Seven patients were treated using the dismembered technique, and one with Y-V plasty. The mean operation time was 185 min (range 150-240), and all procedures were completed laparoscopically. No blood transfusions were required intra- or postoperatively. The mean hospital stay was 2.8 days (range 2-4). Two patients (25%) experienced postoperative complications (one Clavien grade II and one Clavien grade IIIa). The mean follow-up period was 39 months (range 18-78), with a success rate of 87.5%.</p><p><strong>Conclusions: </strong>This study contributes additional evidence that rLP is an effective and reliable treatment for secondary UPJO, achieving high success rates despite its technical challenges.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"58"},"PeriodicalIF":1.7,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11948842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC UrologyPub Date : 2025-03-20DOI: 10.1186/s12894-024-01684-5
Yixuan Mou, Yeqing Mao, Zhenghong Liu, Pu Zhang, Yunkai Yang, Xiaolong Qi, Dahong Zhang, Qijun Wo
{"title":"Robot-assisted radical cystectomy with the clinical application of \"Y-shaped\" end-to-side ureteral anastomosis in elderly and obese patients.","authors":"Yixuan Mou, Yeqing Mao, Zhenghong Liu, Pu Zhang, Yunkai Yang, Xiaolong Qi, Dahong Zhang, Qijun Wo","doi":"10.1186/s12894-024-01684-5","DOIUrl":"10.1186/s12894-024-01684-5","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical effect and safety of \"Y-shaped\" end-to-side ureteral anastomosis with robotic endoscopic technique in radical cystectomy (RC) and urinary diversion (UD) in elderly and obese patients with bladder cancer.</p><p><strong>Materials and methods: </strong>We retrospectively reviewed the records of 10 patients with bladder cancer who underwent robot-assisted laparoscopic radical cystectomy and \"Y-shaped\" end-to-side ureteral anastomosis under general anesthesia at Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China, 310014) from October 2018 to January 2021. Demographic and clinical data are summarized. The incidence of postoperative complications such as papillary retraction, ureteral stricture, anastomotic stenosis, anastomotic fistula and ureteral calculi were observed and analyzed.</p><p><strong>Results: </strong>A total of 10 elderly and obese patients successfully underwent RC with \"Y-shaped\" end-to-side ureteral anastomosis in this research. Median age was (80.6 ± 5.7) y and BMI was (25.12 ± 3.83) kg/m<sup>2</sup>. The operation time was (95 ± 26) min and the estimated intraoperative blood loss was (100.5 ± 35.6) ml, with no perioperative blood transfusion and no readmission 30 days after operation. No serious complications above Clavien-Dindo grade 4 occurred in the early (≤ 30 d) and late (> 30 d) after surgery. 1 patient developed fever three days after operation and was cured by strengthening anti-infection. 1 patient had a small amount of urine leakage at the anastomotic site after operation, and recovered after strengthening nutrition and maintaining the patency of abdominal drainage tube and single J tube. Postoperatively, the patients replaced the single J tube regularly and were followed up for 3-28 months (average 15 months) until April 10, 2021. In two cases, the ureterostomy nipple was slightly retracted and collapsed without special treatment. one case formed ureteral calculi and was treated conservatively. No ureteral stenosis, necrosis, anastomotic stenosis or severe anastomotic fistula, hernia around the stoma occurred. No visceral metastases or new lesions of urothelial carcinoma were observed. All patients were satisfied with the postoperative quality of life.</p><p><strong>Conclusions: </strong>The robot-assisted \"Y-shaped\" end-to-side ureteral anastomosis technique performed intracorporeally seems to be a straightforward, secure, and viable approach. It is considered suitable for radical resection of bladder cancer and urinary diversion in elderly and obese patients.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"56"},"PeriodicalIF":1.7,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BMC UrologyPub Date : 2025-03-20DOI: 10.1186/s12894-025-01741-7
Wang Zhize, Jiayidaer Dannier, Ma Nieying, Xiang Jianjian, Ying Shihong, Yu Jianjun
{"title":"A case report of urethral corpus cavernosum pseudoaneurysm formation after ultrasound-guided transperineal prostate biopsy.","authors":"Wang Zhize, Jiayidaer Dannier, Ma Nieying, Xiang Jianjian, Ying Shihong, Yu Jianjun","doi":"10.1186/s12894-025-01741-7","DOIUrl":"10.1186/s12894-025-01741-7","url":null,"abstract":"<p><strong>Background: </strong>Prostate biopsy is a critical procedure for diagnosing prostate cancer, with severe complications being relatively uncommon. This report presents a complex case of an elderly patient who developed urethral cavernous pseudoaneurysm, persistent bleeding, and disseminated intravascular coagulation (DIC) following ultrasound-guided transperineal prostate biopsy. The patient was managed through timely diagnosis and intervention by a multidisciplinary team, ultimately achieving bleeding control and clinical stabilization.</p><p><strong>Conclusion: </strong>Prompt imaging evaluation, an individualized treatment plan, and effective multidisciplinary collaboration are essential for managing such complex cases.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"25 1","pages":"57"},"PeriodicalIF":1.7,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11924697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}