单中心回顾性研究：柔性导流输尿管导管套联合一次性柔性输尿管镜及经皮肾镜取石治疗> 2.5 cm肾结石的比较研究。

IF 1.9 3区医学 Q3 UROLOGY & NEPHROLOGY

BMC Urology Pub Date : 2025-09-02 DOI:10.1186/s12894-025-01930-4

Guoqing Liu, Xin Zhang, Zhaorong Xu, Xiao Li

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引用次数: 0

摘要

背景与目的：在行逆行肾内手术（RIRS）时，与传统输尿管导管鞘（UAS）相比，柔性可导航的吸力输尿管导管鞘（FANs）可减少碎石次数，提高结石清除率（SFR）。它们在输尿管镜碎石术中得到了广泛的应用。目前，输尿管镜柔性输尿管镜在治疗大肾结石方面也显示出显著的效果。因此，本研究的目的是探讨一次性柔性输尿管镜（su-fURS）联合FANs治疗大于2.5 cm肾结石的疗效，并与经皮肾镜取石术（PCNL）进行比较。方法：选取山东第二医科大学第一附属医院2024年1月至2024年12月接受2.5 ~ 3.8 cm肾结石治疗的患者资料。根据手术方式不同分为PCNL组和FANs组。收集两组患者的一般资料、术中及术后相关资料进行比较，P结果：本研究共纳入76例患者（PCNL 41例，FANs 35例），两组均获得了非常好的SFR (85%, 93% vs. 80%, 91% P = 0.536, 0.840)，差异无统计学意义。PCNL组平均手术时间较短（99.39 vs. 135.49 min） P结论：fan联合su-FURS治疗大于2.5 cm肾结石的SFR高，患者疼痛少，恢复快，值得临床推广应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

A comparative study of flexible and navigable suction ureteral access sheath combined with single-use flexible ureteroscopes and percutaneous nephrolithotomy in the treatment of kidney stones > 2.5 cm: a single-center retrospective study.

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Background and objective: When performing retrograde intrarenal surgery (RIRS), compared with conventional ureteral access sheaths (UAS), flexible and navigable suction ureteral access sheaths (FANs) can reduce the number of lithotripsy sessions and increase the stone-free rate (SFR). They have been widely applied in flexible ureteroscopic lithotripsy (FURL). Currently, ureteroscopic flexible ureteroscopes equipped with FANs are also showing remarkable outcomes in the treatment of large kidney stones. Therefore, the objective of this study was to explore the efficacy of single-use flexible ureteroscopes (su-fURS) combined with FANs in the treatment of kidney stones larger than 2.5 cm and to compare it with percutaneous nephrolithotomy (PCNL).

Methods: Data of patients who underwent treatment of 2.5-3.8 cm kidney stones in the First Affiliated Hospital of Shandong Second Medical University from January 2024 to December 2024 were included in the study. According to the different surgical methods, they were divided into PCNL group and FANs group. The general data, intraoperative and postoperative related data of the patients in the two groups were collected and compared, where P < 0.05 represents statistical significance.

Results: A total of 76 patients (41 PCNL, 35 FANs) were included in this study, and both groups achieved a very favorable SFR (85%, 93% vs. 80%, 91% P = 0.536, 0.840), and the difference was not statistically significant. The PCNL group had a shorter mean operative time (99.39 vs. 135.49 min P < 0.001) and a lower mean hospitalization cost (22, 865.60 vs. 26,031.91 ¥ P < 0.001). The FANs had a lower level of postoperative hemoglobin (Hb) drop (6.31 vs. 11.05 g/L P = 0.010) and a less severe level of postoperative pain (1.97 vs. 3.41 points P < 0.001), faster postoperative recovery (3.29 vs. 6.54d P < 0.001).

Conclusions: FANs combined with su-FURS for the treatment of kidney stones larger than 2.5 cm have a high SFR, with less pain and quicker recovery for patients, making it a method worth promoting and applying in the clinic.

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来源期刊

BMC Urology UROLOGY & NEPHROLOGY-

CiteScore

3.20

自引率

0.00%

发文量

177

审稿时长

>12 weeks

期刊介绍： BMC Urology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of urological disorders, as well as related molecular genetics, pathophysiology, and epidemiology. The journal considers manuscripts in the following broad subject-specific sections of urology: Endourology and technology Epidemiology and health outcomes Pediatric urology Pre-clinical and basic research Reconstructive urology Sexual function and fertility Urological imaging Urological oncology Voiding dysfunction Case reports.