Bio-medical materials and engineering最新文献

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Rapidly degradable konjac glucomannan hydrogels cross-linked with olsalazine for colonic drug release. 与奥萨拉嗪交联的可快速降解魔芋葡甘露聚糖水凝胶用于结肠药物释放。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-230066
Qiao Zhang, Huili Fu, Yunfei Zhang, Liang Li, Guoping Yan
{"title":"Rapidly degradable konjac glucomannan hydrogels cross-linked with olsalazine for colonic drug release.","authors":"Qiao Zhang, Huili Fu, Yunfei Zhang, Liang Li, Guoping Yan","doi":"10.3233/BME-230066","DOIUrl":"10.3233/BME-230066","url":null,"abstract":"<p><strong>Background: </strong>Polysaccharide hydrogel is one of the most important materials for the colon target drug release system. However, the degradation time of polysaccharide hydrogel is much longer than the retention time in the colon. The drugs are expelled from the body before being released.</p><p><strong>Objective: </strong>In order to match the degradation of drug carriers and their retention time in the colon, a rapidly degradable konjac glucomannan (KGM) hydrogel was designed for colon target drug release.</p><p><strong>Methods: </strong>A crosslinker containing azo bond, olsalazine, was used to prepare the rapidly degradable KGM hydrogel. The degradation and drug release of the hydrogels with different crosslinking densities in the normal buffer and the human fecal medium were studied to evaluate the efficiency of colon drug release.</p><p><strong>Results: </strong>More than 50% of the KGM hydrogel by weight was degraded and more than 60% of the 5-fluorouracil (5-Fu) was released within 48 h in 5% w/v human fecal medium.</p><p><strong>Conclusion: </strong>The drug was released more rapidly in a simulated colon environment than in a normal buffer. Furthermore, the drug release was controlled by the degradation of the hydrogel. The KGM hydrogel containing azo crosslinker has great potential for colon drug release.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"125-137"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10651986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatial preference behavior of robo-pigeons induced by electrical stimulus targeting fear nuclei. 以恐惧核为目标的电刺激诱发机器人鸽的空间偏好行为
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-240048
Yanna Ping, Huanhuan Peng, Yongjun Zhu, Yuhao Feng, Yexin Zhang, Xiaomin Qi, Xinyu Liu
{"title":"Spatial preference behavior of robo-pigeons induced by electrical stimulus targeting fear nuclei.","authors":"Yanna Ping, Huanhuan Peng, Yongjun Zhu, Yuhao Feng, Yexin Zhang, Xiaomin Qi, Xinyu Liu","doi":"10.3233/BME-240048","DOIUrl":"10.3233/BME-240048","url":null,"abstract":"<p><strong>Background: </strong>Numerous studies have confirmed that stimulating the mid-brain motor nuclei can regulate movement forcibly for robo-pigeons, but research on behavior modulation using non-motor nuclei is scarce.</p><p><strong>Objective: </strong>In this study, we constructed a spatial preference behavior by stimulating the stratum griseum periventriculare (SGP), a nucleus correlated with fear and escape, for robo-pigeons.</p><p><strong>Methods: </strong>The study was carried out in a square-enclosed experimental field, with a designated box serving as the 'safe' area for the robo-pigeons. If the robo-pigeon exits this area, the SGP will be stimulated. After a brief training period, the robo-pigeons will have a clear spatial preference for the box.</p><p><strong>Results: </strong>The result from five pigeons has shown that, after simple training, the animals develop a spatial preference for the box. They can quickly return to the box in any situation when the SGP is stimulated, with a success rate exceeding 80% (89.0 ± 6.5%). Moreover, this behavior is highly stable and remains consistent, unaffected by changes in the location of the box or the interference box.</p><p><strong>Conclusion: </strong>The results prove that using the electrical stimulus could enable animals to accomplish more complex tasks. It may offer a novel approach to regulating pigeon behavior and further advance the study of cyborg animals.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"465-474"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141598397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aloe vera mucilage loaded gelatin electrospun fibers contained in polylactic acid coaxial system and polylactic acid and poly(e-caprolactone) tri-layer membranes for tissue engineering. 用于组织工程的聚乳酸同轴系统和聚乳酸与聚(e-己内酯)三层膜所含的芦荟粘液负载明胶电纺纤维。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-240050
María Mónica Castillo Ortega, Jesús Manuel Quiroz Castillo, Teresa Del Castillo Castro, Dora Evelia Rodriguez Felix, Hisila Del Carmen Santacruz Ortega, Octavio Manero, Karla Alejandra Lopez Gastelum, Lerma Hanaiy Chan Chan, Diego Hernandez Martinez, Jose Agustin Tapia Hernández, Damian Francisco Plascencia Martínez
{"title":"Aloe vera mucilage loaded gelatin electrospun fibers contained in polylactic acid coaxial system and polylactic acid and poly(e-caprolactone) tri-layer membranes for tissue engineering.","authors":"María Mónica Castillo Ortega, Jesús Manuel Quiroz Castillo, Teresa Del Castillo Castro, Dora Evelia Rodriguez Felix, Hisila Del Carmen Santacruz Ortega, Octavio Manero, Karla Alejandra Lopez Gastelum, Lerma Hanaiy Chan Chan, Diego Hernandez Martinez, Jose Agustin Tapia Hernández, Damian Francisco Plascencia Martínez","doi":"10.3233/BME-240050","DOIUrl":"10.3233/BME-240050","url":null,"abstract":"<p><strong>Background: </strong>Polymeric electrospun mats have been used as scaffolds in tissue engineering for the development of novel materials due to its characteristics. The usage of synthetic materials has gone in decline due to environmental problems associated with their synthesis and waste disposal. Biomaterials such as biopolymers have been used recently due to good compatibility on biological applications and sustainability.</p><p><strong>Objective: </strong>The purpose of this work is to obtain novel materials based on synthetic and natural polymers for applications on tissue engineering.</p><p><strong>Methods: </strong>Aloe vera mucilage was obtained, chemically characterized, and used as an active compound contained in electrospun mats. Polymeric scaffolds were obtained in single, coaxial and tri-layer structures, characterized and evaluated in cell culture.</p><p><strong>Results: </strong>Mucilage loaded electrospun fibers showed good compatibility due to formation of hydrogen bonds between polymers and biomolecules from its structure, evidenced by FTIR spectra and thermal properties. Cell viability test showed that most of the obtained mats result on viability higher than 75%, resulting in nontoxic materials, ready to be used on scaffolding applications.</p><p><strong>Conclusion: </strong>Mucilage containing fibers resulted on materials with potential use on scaffolding applications due to their mechanical performance and cell viability results.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"387-399"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141537501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced mechanic properties of calcium phosphate cements via mussel-inspired adhesive as bone substitute: Highlights of their interactions. 通过贻贝启发粘合剂作为骨替代物增强磷酸钙水门汀的力学性能:它们之间相互作用的亮点。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-230017
Rupan Yuan, Sijie Zhou, Xiong Xiong, Dan Yang, Donghu Lin, Taiyi Li, Bin He, Guihua Wei, Shuxin Qu
{"title":"Enhanced mechanic properties of calcium phosphate cements via mussel-inspired adhesive as bone substitute: Highlights of their interactions.","authors":"Rupan Yuan, Sijie Zhou, Xiong Xiong, Dan Yang, Donghu Lin, Taiyi Li, Bin He, Guihua Wei, Shuxin Qu","doi":"10.3233/BME-230017","DOIUrl":"10.3233/BME-230017","url":null,"abstract":"<p><strong>Background: </strong>Inspired by natural bones, many organic components were added to Calcium Phosphate Cements (CPCs) to improve their mechanical strength. However, the strength of these composite CPCs is limited by the low strength of organic components itself and the weak interaction between organic components and CPCs.</p><p><strong>Objective: </strong>Firstly, a composite CPC containing mussel-inspired adhesive, Poly-(Dopamine Methacrylamide-co-2-methoxy Ethylacrylate) (pDM) was developed. Secondly, the interactions between pDM and CPC and their effect on mechanical properties were investigated.</p><p><strong>Methods: </strong>The interactions between pDM and CPC were performed by Nuclear Magnetic Resonance, Laser Raman, X-ray Photoelectron Spectroscopy, Fourier Transform-Infrared Spectroscopy and X-ray Diffraction Analysis.</p><p><strong>Results: </strong>The toughness and compressive strength of pDM-CPC scaffold were both significantly enhanced, because of the enhanced interface binding strength among CPC and pDM due to their interaction and the improved mechanical strength of pDM owing to its self-oxidation cross-linking. The toughness of pDM-CPC scaffolds increased with the increased contents of pDM, while pDM-CPC scaffold containing 35 wt.% pDM had the highest compressive strength of all, which the latter was more than five times compared to that of CPC.</p><p><strong>Conclusion: </strong>The mechanically strong pDM-CPC scaffolds has potential application in bone regeneration as well as in craniofacial and orthopedic repair.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"13-26"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10031624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the efficacy of the punch-out technique in systemic-to-pulmonary shunts: A computational fluid dynamics approach. 评估全身-肺分流术中打孔技术的功效:计算流体动力学方法。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-240022
Shiho Yamazaki, Ryosuke Kowatari, Tetsuya Yano, Hanae Sasaki, Kazuyuki Daitoku, Masahito Minakawa
{"title":"Evaluating the efficacy of the punch-out technique in systemic-to-pulmonary shunts: A computational fluid dynamics approach.","authors":"Shiho Yamazaki, Ryosuke Kowatari, Tetsuya Yano, Hanae Sasaki, Kazuyuki Daitoku, Masahito Minakawa","doi":"10.3233/BME-240022","DOIUrl":"10.3233/BME-240022","url":null,"abstract":"<p><strong>Background: </strong>Systemic-to-pulmonary shunt is a palliative procedure used to decrease pulmonary blood flow in congenital heart diseases. Shunt stenosis or occlusion has been reported to be associated with mortality; therefore, the management of thrombotic complications remains a challenge for most congenital cardiovascular surgeons. Despite its importance, the optimal method for shunt anastomosis remains unclear.</p><p><strong>Objective: </strong>The study investigates the clinical benefits of the punch-out technique over conventional methods in the anastomosis process of Systemic-to-pulmonary shunt, focusing on its potential to reduce shunt-related complications.</p><p><strong>Methods: </strong>Anastomotic models were created by two different surgeons employing both traditional slit and innovative punch-out techniques. Computational tomography was performed to construct three-dimensional models for computational fluid dynamics (CFD) analysis. We assessed the flow pattern, helicity, magnitude of wall shear stress, and its gradient.</p><p><strong>Results: </strong>The anastomotic flow area was larger in the model using the punch-out technique than in the slit model. In CFD simulation, we found that using the punch-out technique decreases the likelihood of establishing a high wall shear stress distribution around the anastomosis line in the model.</p><p><strong>Conclusion: </strong>The punch-out technique emerges as a promising method in SPS anastomosis, offering a reproducible and less skill-dependent alternative that potentially diminishes the risk of shunt occlusion, thereby enhancing patient outcomes.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"425-437"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141909753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous tissue reaction to a novel nano zinc oxide eugenol dental cement. 新型纳米氧化锌丁香酚牙水泥的皮下组织反应。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-230118
Rohmat Nursin, Masitah Hayati Harun, Dasmawati Mohamad, Siti Khadijah Mohd Bakhori, Shahrom Mahmud
{"title":"Subcutaneous tissue reaction to a novel nano zinc oxide eugenol dental cement.","authors":"Rohmat Nursin, Masitah Hayati Harun, Dasmawati Mohamad, Siti Khadijah Mohd Bakhori, Shahrom Mahmud","doi":"10.3233/BME-230118","DOIUrl":"10.3233/BME-230118","url":null,"abstract":"<p><strong>Background: </strong>Zinc oxide eugenol (ZOE) cement is a popular dental material due mainly to its analgesic, antibacterial and anti-inflammatory effects. The formulation of ZOE cement from nano particle-sized zinc oxide (ZnO) has the potential to increase these properties as well as reduce its adverse effects to the surrounding tissues.</p><p><strong>Objective: </strong>This study evaluated the subcutaneous tissue response towards nano ZOE cements (ZOE-A and ZOE-B) in comparison to conventional ZOE (ZOE-K).</p><p><strong>Methods: </strong>Test materials were implanted into 15 New Zealand white rabbits. Tissue samples were obtained after 7, 14, and 30 days (n = 5 per period) for histopathological evaluation of inflammatory cell infiltrate, fibrous tissue condensation, and abscess formation.</p><p><strong>Results: </strong>ZOE-A showed the lowest score for the variable macrophage and lymphocyte at day 7. Both ZOE-A and ZOE-B presented lower fibrous tissue condensation and abscess formation compared to conventional ZOE-K. By day 30, ZOE-A exhibited less lymphocytic and neutrophilic infiltrate compared to the other materials, while ZOE-B had the lowest score for macrophages. ZOE-K exerted higher inflammatory cell response at almost all of the experimental periods. All of the materials resulted in thin fiber condensation after 30 days.</p><p><strong>Conclusions: </strong>Rabbit tissue implanted with ZOE-A and ZOE-B showed better response compared to ZOE-K.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"139-151"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138440236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Varus/valgus stability in imageless robotic-assisted total knee arthroplasty applying three-dimensional assessment of varus/valgus stress X-rays. 应用内翻/外翻应力x射线三维评估在无图像机器人辅助全膝关节置换术中的内翻/外翻稳定性。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-230146
Hiroki Hijikata, Tomoharu Mochizuki, Keisuku Maeda, Osamu Tanifuji, Go Omori, Noriaki Yamamoto, Hiroyuki Kawashima
{"title":"Varus/valgus stability in imageless robotic-assisted total knee arthroplasty applying three-dimensional assessment of varus/valgus stress X-rays.","authors":"Hiroki Hijikata, Tomoharu Mochizuki, Keisuku Maeda, Osamu Tanifuji, Go Omori, Noriaki Yamamoto, Hiroyuki Kawashima","doi":"10.3233/BME-230146","DOIUrl":"10.3233/BME-230146","url":null,"abstract":"<p><strong>Background: </strong>The postoperative varus/valgus stability assessment in stress X-rays has been established as an evaluation index. However, it is performed by the two-dimensional (2D) method rather than the three-dimensional (3D) method.</p><p><strong>Objective: </strong>This study aimed to identify the precision and reproducibility of measuring varus/valgus stress X-rays three-dimensionally and to examine varus/valgus stability under anesthesia in imageless robotic assisted total knee arthroplasty (rTKA).</p><p><strong>Methods: </strong>This prospective study analyzed 52 consecutive rTKAs (five males, 67 ± 5.3 years; 47 females, 74 ± 5.9 years). Postoperative varus/valgus stress X-rays in knee extension under anesthesia at manual maximum stress were three-dimensionally assessed by 2D-3D image matching technique using the 3D bone and component models. Varus/valgus angle between components (VV angle) in no stress, valgus stress, varus stress, medial joint opening (MJO), and lateral joint opening (LJO) were evaluated, clarifying this method's precision and reproducibility and valgus/varus stability.</p><p><strong>Results: </strong>All parameters' precision and reproducibility had <1° mean differences and high intra- and inter-class correlation coefficients. Bland-Altman plots showed no fixed and proportional bias. Non-stress VV angle, valgus VV angle, varus VV angle, MJO, and LJO were 3.6 ± 1.2°, 1.0 ± 1.4°, 7.1 ± 1.9°, 1.5 ± 1.0 mm, and 2.8 ± 2.7 mm, respectively.</p><p><strong>Conclusion: </strong>This prospective study demonstrated that (1) the three-dimensional measurement method provided sufficient precision and reproducibility, and (2) the rTKAs could achieve good postoperative varus/valgus stability with a small standard deviation.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"179-189"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138476781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surface hardening of Ti-Al-V superalloy spinal implant by using the boronization method. 使用硼化方法对 Ti-Al-V 超合金脊柱植入物进行表面硬化。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-230033
Mehdi Hekimoğlu, Hıdır Özer, Kamil Kiraz, Ceylan Onursal, Ferit Siyahcan, Ali Fahir Özer
{"title":"Surface hardening of Ti-Al-V superalloy spinal implant by using the boronization method.","authors":"Mehdi Hekimoğlu, Hıdır Özer, Kamil Kiraz, Ceylan Onursal, Ferit Siyahcan, Ali Fahir Özer","doi":"10.3233/BME-230033","DOIUrl":"10.3233/BME-230033","url":null,"abstract":"<p><strong>Background: </strong>We compared the raw Ti-Al-V super alloy transpedicular implant screws with boronized and surface-hardened transpedicular implant screws.</p><p><strong>Objective: </strong>To improve patients' postoperative prognosis with the production of harder and less fragile screws.</p><p><strong>Methods: </strong>Surface hardening was achieved by applying green-body encapsulation of the specimen with elemental boron paste which is sintered at elevated temperatures to ensure the boron-metal diffusion. Boron transported into the Ti-Al-V super alloy matrix gradually while suppressing aluminum and a homogeneously boronized surface with a thickness of ∼15 microns was obtained. The uniform external shell was enriched with TiB2, which is one of the hardest ceramics. The Ti-Al-V core material, where boron penetration diminishes, shows cohesive transition and ensures intact core-surface structure.</p><p><strong>Results: </strong>Scanning electron microscope images confirmed a complete homogeneous, uniform and non-laminating surface formation. Energy-dispersive X-ray monitored the elemental structural mapping and proved the replacement of the aluminum sites on the surface with boron ending up the TiB2. The procedure was 8.6 fold improved the hardness and the mechanical resistance of the tools.</p><p><strong>Conclusions: </strong>Surface-hardened, boronized pedicular screws can positively affect the prognosis. In vivo studies are needed to prove the safety of use.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"39-52"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10319309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental characterization of motion resistance of the sacroiliac joint. 骶髂关节运动阻力的实验特征。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-230041
Ryota Toyohara, Niels Hammer, Toshiro Ohashi
{"title":"Experimental characterization of motion resistance of the sacroiliac joint.","authors":"Ryota Toyohara, Niels Hammer, Toshiro Ohashi","doi":"10.3233/BME-230041","DOIUrl":"10.3233/BME-230041","url":null,"abstract":"<p><strong>Background: </strong>The human sacroiliac joint (SIJ) in vivo is exposed to compressive and shearing stress environment, given the joint lines are almost parallel to the direction of gravity. The SIJ supports efficient bipedal walking. Unexpected or unphysiological, repeated impacts are believed to cause joint misalignment and result in SIJ pain. In the anterior compartment of the SIJ being synovial, the articular surface presents fine irregularities, potentially restricting the motion of the joints.</p><p><strong>Objective: </strong>To clarify how the SIJ articular surface affects the resistance of the motion under physiological loading.</p><p><strong>Methods: </strong>SIJ surface models were created based on computed tomography data of three patients and subsequently 3D printed. Shear resistance was measured in four directions and three combined positions using a customized setup. In addition, repositionability of SIJs was investigated by unloading a shear force.</p><p><strong>Results: </strong>Shear resistance of the SIJ was the highest in the inferior direction. It changed depending on the direction of the shear and the alignment position of the articular surface.</p><p><strong>Conclusion: </strong>SIJ articular surface morphology is likely designed to accommodate upright bipedal walking. Joint misalignment may in consequence increase the risk of subluxation.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"53-63"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10302838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability and validity of estimated angles information assessed using inertial measurement unit-based motion sensors. 使用基于惯性测量单元的运动传感器评估估计角度信息的可靠性和有效性。
IF 1 4区 医学
Bio-medical materials and engineering Pub Date : 2024-01-01 DOI: 10.3233/BME-240031
Taiki Morikawa, Nariyuki Mura, Toshiaki Sato, Hiroshi Katoh
{"title":"Reliability and validity of estimated angles information assessed using inertial measurement unit-based motion sensors.","authors":"Taiki Morikawa, Nariyuki Mura, Toshiaki Sato, Hiroshi Katoh","doi":"10.3233/BME-240031","DOIUrl":"10.3233/BME-240031","url":null,"abstract":"<p><strong>Background: </strong>Inertial measurement unit (IMU)-based motion sensors are affordable, and their use is appropriate for rehabilitation. However, regarding the accuracy of estimated angle information obtained from this sensor, it is reported that it is likely affected by velocity.</p><p><strong>Objective: </strong>The present study investigated the reliability and validity of the angle information obtained using IMU-based sensors compared with a three-dimensional (3D) motion analyzer.</p><p><strong>Methods: </strong>The Euler angle obtained using the 3D motion analyzer and the angle obtained using the IMU-based sensor (IMU angle) were compared. Reliability was assessed by comparing the Bland-Altman analysis, intra-class correlation coefficient (ICC) (1,1), and cross-correlation function. The root mean square (RMS) error, ICC (2,1), and cross-correlation function were used to compare data on the Euler and IMU angles to evaluate the validity.</p><p><strong>Results: </strong>Regarding reliability, the Bland-Atman analysis indicated no fixed or proportional bias in the angle measurements. The measurement errors ranged from 0.2° to 3.2°. In the validity, the RMS error ranged from 0.3° to 2.2°. The ICCs (2,1) were 0.9. The cross-correlation functions were >0.9, which indicated a high degree of agreement.</p><p><strong>Conclusion: </strong>The IMU-based sensor had a high reliability and validity. The IMU angle may be used in rehabilitation.</p>","PeriodicalId":9109,"journal":{"name":"Bio-medical materials and engineering","volume":" ","pages":"439-450"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141730999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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