Multi-scale topology optimisation design and mechanical property analysis of porous interbody fusion cage.

Abstract

BackgroundTitanium (Ti) and polyether ether ketone (PEEK) interbody fusion cages cause postoperative stress shielding problems. The porous cage design is one of the solutions advanced to mitigate this problem.ObjectiveExploring the mitigation of stress shielding with a porous interbody fusion cage after surgery for idiopathic scoliosis.MethodsThe porous interbody fusion cage was constructed based on the multiscale topology optimisation method, and the postoperative lumbar spine models implanted with it. The porous Ti and PEEK fusion cages were evaluated under physiological conditions to investigate their mechanical properties.ResultsThe volume of the porous fusion cage was reduced by 52.57%, and the stress was increased by 242.76% and 252.46% compared with the Ti and PEEK fusion cage; the modulus of elasticity of the porous fusion cage was reduced by 76.85%, and the strain was increased by 131.40%∼686.51% compared with the Ti cage; the porous fusion cage increased L3 cortical bone stress by 13.36% and 13.52% and cancellous bone by 82.93% and 76.72%, respectively, compared with the original interbody fusion cages.ConclusionThe porous interbody fusion cage has a much more lightweight design which facilitates growth of bone tissue. However, a frame structure should be constructed to minimize issues with stress peaks and localised stress concentrations. It also has a significantly lower stiffness which helps alleviate vertebral stress shielding, further fostering bone growth. The porous fusion cage thus meets the clinical requirements for better fusion outcomes.